FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1692, 200 aa
  1>>>pF1KE1692 200 - 200 aa - 200 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9411+/-0.000284; mu= 16.3861+/- 0.018
 mean_var=72.3257+/-14.343, 0's: 0 Z-trim(119.8): 5  B-trim: 404 in 1/53
 Lambda= 0.150809
 statistics sampled from 34151 (34156) to 34151 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.4), width:  16
 Scan time:  5.990

The best scores are:                                      opt bits E(85289)
NP_742152 (OMIM: 607403) interferon lambda-1 precu ( 200) 1337 299.1 3.2e-81
NP_742151 (OMIM: 607402,609532) interferon lambda- ( 196)  899 203.8 1.5e-52
XP_005258822 (OMIM: 607402,609532) PREDICTED: inte ( 200)  899 203.8 1.5e-52
NP_742150 (OMIM: 607401) interferon lambda-2 [Homo ( 200)  884 200.5 1.5e-51
NP_001263183 (OMIM: 615090) interferon lambda-4 pr ( 179)  138 38.2  0.0099


>>NP_742152 (OMIM: 607403) interferon lambda-1 precursor  (200 aa)
 initn: 1337 init1: 1337 opt: 1337  Z-score: 1579.2  bits: 299.1 E(85289): 3.2e-81
Smith-Waterman score: 1337; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200)

               10        20        30        40        50        60
pF1KE1 MAAAWTVVLVTLVLGLAVAGPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MAAAWTVVLVTLVLGLAVAGPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 LKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 LHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRD
              130       140       150       160       170       180

              190       200
pF1KE1 LKYVADGNLCLRTSTHPEST
       ::::::::::::::::::::
NP_742 LKYVADGNLCLRTSTHPEST
              190       200

>>NP_742151 (OMIM: 607402,609532) interferon lambda-3 pr  (196 aa)
 initn: 948 init1: 521 opt: 899  Z-score: 1064.3  bits: 203.8 E(85289): 1.5e-52
Smith-Waterman score: 899; 74.1% identity (86.8% similar) in 189 aa overlap (8-191:8-196)

               10        20           30        40        50       
pF1KE1 MAAAWTVVLVTLVLGLAVAGPVPTSK---PTTTGKGCHIGRFKSLSPQELASFKKARDAL
              ::: ..  :.:.: ::...       ..::::..::::::::: .::.:.:::
NP_742 MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDAL
               10        20        30        40        50        60

        60        70        80        90       100         110     
pF1KE1 EESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAG--PALEDVLD
       :::: ::. .: : .:: .:::: :::::::::::::::::::::::.:   ::: ::::
NP_742 EESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLD
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE1 QPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFR
       :::::::::::::.:::::::::::: ::::::::::::::::::: :::::::::::::
NP_742 QPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
              130       140       150       160       170       180

         180       190       200
pF1KE1 LLTRDLKYVADGNLCLRTSTHPEST
       ::::::. ::.:.::.         
NP_742 LLTRDLNCVASGDLCV         
              190               

>>XP_005258822 (OMIM: 607402,609532) PREDICTED: interfer  (200 aa)
 initn: 948 init1: 521 opt: 899  Z-score: 1064.2  bits: 203.8 E(85289): 1.5e-52
Smith-Waterman score: 899; 74.1% identity (86.8% similar) in 189 aa overlap (8-191:12-200)

                   10        20           30        40        50   
pF1KE1     MAAAWTVVLVTLVLGLAVAGPVPTSK---PTTTGKGCHIGRFKSLSPQELASFKKA
                  ::: ..  :.:.: ::...       ..::::..::::::::: .::.:
XP_005 MKLDMTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRA
               10        20        30        40        50        60

            60        70        80        90       100         110 
pF1KE1 RDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAG--PALE
       .::::::: ::. .: : .:: .:::: :::::::::::::::::::::::.:   ::: 
XP_005 KDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALG
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KE1 DVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTF
       :::::::::::::::::.:::::::::::: ::::::::::::::::::: :::::::::
XP_005 DVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTF
              130       140       150       160       170       180

             180       190       200
pF1KE1 NLFRLLTRDLKYVADGNLCLRTSTHPEST
       ::::::::::. ::.:.::.         
XP_005 NLFRLLTRDLNCVASGDLCV         
              190       200         

>>NP_742150 (OMIM: 607401) interferon lambda-2 [Homo sap  (200 aa)
 initn: 930 init1: 509 opt: 884  Z-score: 1046.5  bits: 200.5 E(85289): 1.5e-51
Smith-Waterman score: 884; 72.3% identity (85.9% similar) in 191 aa overlap (6-191:10-200)

                   10        20           30        40        50   
pF1KE1     MAAAWTVVLVTLVLGLAVAGPVPTSK---PTTTGKGCHIGRFKSLSPQELASFKKA
                : ::: ..  :.:.: ::...       ..::::..::::::::: .::.:
NP_742 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
               10        20        30        40        50        60

            60        70        80        90       100         110 
pF1KE1 RDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAG--PALE
       .::::::: ::.  : : .:: .:::: :::::::.:::::::::::::::.:   ::: 
NP_742 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KE1 DVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTF
       ::::::::::::::::..:::::::::::: ::::::::.:::::::::: :::::::::
NP_742 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
              130       140       150       160       170       180

             180       190       200
pF1KE1 NLFRLLTRDLKYVADGNLCLRTSTHPEST
       ::::::::::. ::.:.::.         
NP_742 NLFRLLTRDLNCVASGDLCV         
              190       200         

>>NP_001263183 (OMIM: 615090) interferon lambda-4 precur  (179 aa)
 initn: 177 init1:  98 opt: 138  Z-score: 170.0  bits: 38.2 E(85289): 0.0099
Smith-Waterman score: 165; 29.3% identity (53.9% similar) in 191 aa overlap (8-191:5-179)

               10        20        30        40        50          
pF1KE1 MAAAWTVVLVTLVLGLAVAGPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEE-
              : .... :: :   : .. :    . : .....:: :. ::. :  ::  :: 
NP_001    MRPSVWAAVAAGLWVLCTVIAAAP----RRCLLSHYRSLEPRTLAAAKALRDRYEEE
                  10        20            30        40        50   

      60             70        80        90        100       110   
pF1KE1 SLKLKNWSCS-----SPVFPGNWDLRLLQVRERPVALEAELA-LTLKVLEAAAGPALEDV
       .:.  . .::     .:  :..   :: .: .  .  .: :. :  . :  .::: ::  
NP_001 ALSWGQRNCSFRPRRDPPRPSS-CARLRHVARGIADAQAVLSGLHRSELLPGAGPILE--
            60        70         80        90       100       110  

           120       130       140       150       160       170   
pF1KE1 LDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNL
              :     .. ::..    : :    ..    .: ..  . .:  : .:::.:::
NP_001 ------LLAAAGRDVAACLE---LARPGSSRKVPGAQKRRHKPRRADSPRCRKASVVFNL
                    120          130       140       150       160 

           180       190       200
pF1KE1 FRLLTRDLKYVADGNLCLRTSTHPEST
       .:::: .:. .: .. ::         
NP_001 LRLLTWELRLAAHSGPCL         
             170                  




200 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 05:02:05 2016 done: Sun Nov  6 05:02:06 2016
 Total Scan time:  5.990 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]