Result of FASTA (omim) for
pFN21AE1687
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1687, 199 aa
1>>>pF1KE1687 199 - 199 aa - 199 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9776+/-0.000407; mu= 14.7327+/- 0.025
mean_var=62.2736+/-12.558, 0's: 0 Z-trim(111.2): 49 B-trim: 268 in 2/52
Lambda= 0.162526
statistics sampled from 19719 (19765) to 19719 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.232), width: 16
Scan time: 4.480
The best scores are: opt bits E(85289)
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 1363 328.2 5.5e-90
XP_005262989 (OMIM: 602598) PREDICTED: hematopoiet ( 168) 861 210.4 1.3e-54
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 266 71.0 1.6e-12
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 264 70.5 2.2e-12
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 256 68.6 8.1e-12
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 255 68.4 8.7e-12
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 255 68.4 1.1e-11
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 253 67.9 1.3e-11
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 253 67.9 1.3e-11
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 245 66.0 4.3e-11
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 245 66.1 4.9e-11
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 242 65.4 8e-11
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 241 65.1 9.4e-11
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 239 64.6 1.3e-10
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 239 64.6 1.3e-10
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 228 62.1 7.4e-10
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 216 59.3 5.5e-09
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 212 58.3 1e-08
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 212 58.3 1e-08
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 208 57.4 2e-08
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 206 56.9 2.4e-08
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 200 55.4 6.1e-08
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 189 52.9 4.2e-07
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 166 47.5 1.5e-05
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 166 47.5 1.5e-05
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 161 46.3 3.6e-05
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 161 46.3 3.6e-05
NP_001395 (OMIM: 130593) elongation factor 1-gamma ( 437) 145 42.8 0.00097
XP_016856577 (OMIM: 138333) PREDICTED: glutathione ( 150) 130 39.0 0.0047
>>NP_055300 (OMIM: 602598) hematopoietic prostaglandin D (199 aa)
initn: 1363 init1: 1363 opt: 1363 Z-score: 1736.5 bits: 328.2 E(85289): 5.5e-90
Smith-Waterman score: 1363; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
130 140 150 160 170 180
190
pF1KE1 VQAIPAVANWIKRRPQTKL
:::::::::::::::::::
NP_055 VQAIPAVANWIKRRPQTKL
190
>>XP_005262989 (OMIM: 602598) PREDICTED: hematopoietic p (168 aa)
initn: 861 init1: 861 opt: 861 Z-score: 1101.5 bits: 210.4 E(85289): 1.3e-54
Smith-Waterman score: 1091; 83.9% identity (84.4% similar) in 199 aa overlap (1-199:1-168)
10 20 30 40 50 60
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT
::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKS----------------
10 20 30 40
70 80 90 100 110 120
pF1KE1 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
.::::::::::::::::::::::::::::::::::::::::::::
XP_005 ---------------NLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
50 60 70 80
130 140 150 160 170 180
pF1KE1 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
90 100 110 120 130 140
190
pF1KE1 VQAIPAVANWIKRRPQTKL
:::::::::::::::::::
XP_005 VQAIPAVANWIKRRPQTKL
150 160
>>NP_000841 (OMIM: 138333) glutathione S-transferase Mu (218 aa)
initn: 229 init1: 116 opt: 266 Z-score: 345.8 bits: 71.0 E(85289): 1.6e-12
Smith-Waterman score: 266; 27.8% identity (57.6% similar) in 198 aa overlap (6-192:5-199)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
: :...:: :. :: .. : : .::... ..: :. .: : : .
NP_000 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQ
.: : .:: . :: :: :.... .: :.:: :. .:: . . : . . . .
NP_000 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD
: :.. : : . : .:: .. .:: : :..:...:..:: .:.:. ::
NP_000 DF-EKLKPEYLE-ELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
170 180 190
pF1KE1 NHPRLVTLRKKVQAIPAVANWIKRRPQTKL
: : . .. ... .. ..:
NP_000 AFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
180 190 200 210
>>NP_000552 (OMIM: 138350) glutathione S-transferase Mu (218 aa)
initn: 209 init1: 96 opt: 264 Z-score: 343.3 bits: 70.5 E(85289): 2.2e-12
Smith-Waterman score: 264; 29.2% identity (57.9% similar) in 209 aa overlap (1-192:1-199)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
:: . : :...:: :. :: .. : : .::... ..: :. .: : : .
NP_000 MP-MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-P
.: : .:: . :: :: :.... .: :.:: :. .:: . . :.:. :. :. :
NP_000 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 WAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF
:: .: ....:: :. .. . .:: : :. ::..:..:: .:
NP_000 EFEK---LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF
120 130 140 150 160 170
170 180 190
pF1KE1 KPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
.: :: : : . .. ... .. ..:
NP_000 EPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
180 190 200 210
>>NP_000839 (OMIM: 138380) glutathione S-transferase Mu (218 aa)
initn: 202 init1: 90 opt: 256 Z-score: 333.2 bits: 68.6 E(85289): 8.1e-12
Smith-Waterman score: 256; 28.2% identity (58.4% similar) in 209 aa overlap (1-192:1-199)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
:: . : :.:.:: :. :: .. : : .::... ..: :. .: : : .
NP_000 MP-MTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDT-LDDFMS----CF-P
.: : .:: . :: :: ::.... .: :..: :: . : . . .:. :. :. :
NP_000 LPYL-IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 WAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF
:: .: .... : :.... . .:: . :..:...:..:: ::
NP_000 DFEK---LKPEYLQAL-----PEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVF
120 130 140 150 160 170
170 180 190
pF1KE1 KPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
.:. :: : : . .. ... .. ..:
NP_000 EPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
180 190 200 210
>>NP_671489 (OMIM: 138333) glutathione S-transferase Mu (195 aa)
initn: 229 init1: 116 opt: 255 Z-score: 332.6 bits: 68.4 E(85289): 8.7e-12
Smith-Waterman score: 255; 30.0% identity (57.2% similar) in 180 aa overlap (6-174:5-181)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
: :...:: :. :: .. : : .::... ..: :. .: : : .
NP_671 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQ
.: : .:: . :: :: :.... .: :.:: :. .:: . . : . . . .
NP_671 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD
: :.. : : . : .:: .. .:: : :..:...:..:: .:.:. ::
NP_671 DF-EKLKPEYLE-ELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
170 180 190
pF1KE1 NHPRLVTLRKKVQAIPAVANWIKRRPQTKL
: :
NP_671 AFPNLKDFISRFEVSCGIM
180 190
>>XP_016856574 (OMIM: 138333) PREDICTED: glutathione S-t (254 aa)
initn: 229 init1: 116 opt: 255 Z-score: 330.9 bits: 68.4 E(85289): 1.1e-11
Smith-Waterman score: 255; 30.0% identity (57.2% similar) in 180 aa overlap (6-174:5-181)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
: :...:: :. :: .. : : .::... ..: :. .: : : .
XP_016 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQ
.: : .:: . :: :: :.... .: :.:: :. .:: . . : . . . .
XP_016 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD
: :.. : : . : .:: .. .:: : :..:...:..:: .:.:. ::
XP_016 DF-EKLKPEYLE-ELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
170 180 190
pF1KE1 NHPRLVTLRKKVQAIPAVANWIKRRPQTKL
: :
XP_016 AFPNLKDFISRFECSKCSPCEMSSTLILLLFTDLLLCMRQGVRHSGSCIDDCPILEMSAV
180 190 200 210 220 230
>>XP_011512834 (OMIM: 138360) PREDICTED: glutathione S-t (222 aa)
initn: 124 init1: 69 opt: 253 Z-score: 329.3 bits: 67.9 E(85289): 1.3e-11
Smith-Waterman score: 255; 26.5% identity (63.7% similar) in 204 aa overlap (5-195:6-206)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEV
:: : :.::: : ::...: ...:.. :..: : .... : : ..:..:.
XP_011 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF---MSCFPWAE-KKQDVK
::. : :. :: :.... .: :. :. .: .. . :. . .:... ..::.:
XP_011 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EQMFNELLTYNA--PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN
...: : : : . . : .. :...:.::... ::.. . . .:...
XP_011 LALIQEK-TKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISS
130 140 150 160 170
180 190
pF1KE1 HPRLVTLRKKVQAIPAVANWIK----RRPQTKL
: : .:. ... .:.: .... :.:
XP_011 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
180 190 200 210 220
>>NP_000837 (OMIM: 138360) glutathione S-transferase A2 (222 aa)
initn: 124 init1: 69 opt: 253 Z-score: 329.3 bits: 67.9 E(85289): 1.3e-11
Smith-Waterman score: 255; 26.5% identity (63.7% similar) in 204 aa overlap (5-195:6-206)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEV
:: : :.::: : ::...: ...:.. :..: : .... : : ..:..:.
NP_000 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF---MSCFPWAE-KKQDVK
::. : :. :: :.... .: :. :. .: .. . :. . .:... ..::.:
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EQMFNELLTYNA--PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN
...: : : : . . : .. :...:.::... ::.. . . .:...
NP_000 LALIQEK-TKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISS
130 140 150 160 170
180 190
pF1KE1 HPRLVTLRKKVQAIPAVANWIK----RRPQTKL
: : .:. ... .:.: .... :.:
NP_000 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
180 190 200 210 220
>>NP_001135840 (OMIM: 138380) glutathione S-transferase (191 aa)
initn: 202 init1: 90 opt: 245 Z-score: 320.1 bits: 66.0 E(85289): 4.3e-11
Smith-Waterman score: 245; 30.4% identity (58.1% similar) in 191 aa overlap (1-174:1-181)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
:: . : :.:.:: :. :: .. : : .::... ..: :. .: : : .
NP_001 MP-MTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDT-LDDFMS----CF-P
.: : .:: . :: :: ::.... .: :..: :: . : . . .:. :. :. :
NP_001 LPYL-IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 WAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF
:: .: .... : :.... . .:: . :..:...:..:: ::
NP_001 DFEK---LKPEYLQAL-----PEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVF
120 130 140 150 160 170
170 180 190
pF1KE1 KPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
.:. :: : :
NP_001 EPSCLDAFPNLKDFISRFEHS
180 190
199 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:23:43 2016 done: Sun Nov 6 17:23:44 2016
Total Scan time: 4.480 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]