Result of FASTA (ccds) for
pFN21AE1687
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1687, 199 aa
1>>>pF1KE1687 199 - 199 aa - 199 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7288+/-0.000899; mu= 9.9583+/- 0.054
mean_var=59.1395+/-11.841, 0's: 0 Z-trim(104.5): 33 B-trim: 27 in 1/49
Lambda= 0.166777
statistics sampled from 7905 (7931) to 7905 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.244), width: 16
Scan time: 1.590
The best scores are: opt bits E(32554)
CCDS3640.1 HPGDS gene_id:27306|Hs108|chr4 ( 199) 1363 336.4 7e-93
CCDS807.1 GSTM4 gene_id:2948|Hs108|chr1 ( 218) 266 72.5 2.2e-13
CCDS809.1 GSTM1 gene_id:2944|Hs108|chr1 ( 218) 264 72.0 3e-13
CCDS808.1 GSTM2 gene_id:2946|Hs108|chr1 ( 218) 256 70.1 1.2e-12
CCDS806.1 GSTM4 gene_id:2948|Hs108|chr1 ( 195) 255 69.8 1.2e-12
CCDS4944.1 GSTA2 gene_id:2939|Hs108|chr6 ( 222) 253 69.3 1.9e-12
CCDS44192.1 GSTM2 gene_id:2946|Hs108|chr1 ( 191) 245 67.4 6.4e-12
CCDS4947.1 GSTA3 gene_id:2940|Hs108|chr6 ( 222) 245 67.4 7.4e-12
CCDS4945.1 GSTA1 gene_id:2938|Hs108|chr6 ( 222) 242 66.7 1.2e-11
CCDS4946.1 GSTA5 gene_id:221357|Hs108|chr6 ( 222) 241 66.4 1.4e-11
CCDS811.1 GSTM5 gene_id:2949|Hs108|chr1 ( 218) 239 66.0 2e-11
>>CCDS3640.1 HPGDS gene_id:27306|Hs108|chr4 (199 aa)
initn: 1363 init1: 1363 opt: 1363 Z-score: 1781.0 bits: 336.4 E(32554): 7e-93
Smith-Waterman score: 1363; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 LHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK
130 140 150 160 170 180
190
pF1KE1 VQAIPAVANWIKRRPQTKL
:::::::::::::::::::
CCDS36 VQAIPAVANWIKRRPQTKL
190
>>CCDS807.1 GSTM4 gene_id:2948|Hs108|chr1 (218 aa)
initn: 229 init1: 116 opt: 266 Z-score: 353.8 bits: 72.5 E(32554): 2.2e-13
Smith-Waterman score: 266; 27.8% identity (57.6% similar) in 198 aa overlap (6-192:5-199)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
: :...:: :. :: .. : : .::... ..: :. .: : : .
CCDS80 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQ
.: : .:: . :: :: :.... .: :.:: :. .:: . . : . . . .
CCDS80 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD
: :.. : : . : .:: .. .:: : :..:...:..:: .:.:. ::
CCDS80 DF-EKLKPEYLE-ELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
170 180 190
pF1KE1 NHPRLVTLRKKVQAIPAVANWIKRRPQTKL
: : . .. ... .. ..:
CCDS80 AFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
180 190 200 210
>>CCDS809.1 GSTM1 gene_id:2944|Hs108|chr1 (218 aa)
initn: 209 init1: 96 opt: 264 Z-score: 351.2 bits: 72.0 E(32554): 3e-13
Smith-Waterman score: 264; 29.2% identity (57.9% similar) in 209 aa overlap (1-192:1-199)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
:: . : :...:: :. :: .. : : .::... ..: :. .: : : .
CCDS80 MP-MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-P
.: : .:: . :: :: :.... .: :.:: :. .:: . . :.:. :. :. :
CCDS80 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 WAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF
:: .: ....:: :. .. . .:: : :. ::..:..:: .:
CCDS80 EFEK---LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF
120 130 140 150 160 170
170 180 190
pF1KE1 KPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
.: :: : : . .. ... .. ..:
CCDS80 EPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
180 190 200 210
>>CCDS808.1 GSTM2 gene_id:2946|Hs108|chr1 (218 aa)
initn: 202 init1: 90 opt: 256 Z-score: 340.8 bits: 70.1 E(32554): 1.2e-12
Smith-Waterman score: 256; 28.2% identity (58.4% similar) in 209 aa overlap (1-192:1-199)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
:: . : :.:.:: :. :: .. : : .::... ..: :. .: : : .
CCDS80 MP-MTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDT-LDDFMS----CF-P
.: : .:: . :: :: ::.... .: :..: :: . : . . .:. :. :. :
CCDS80 LPYL-IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 WAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF
:: .: .... : :.... . .:: . :..:...:..:: ::
CCDS80 DFEK---LKPEYLQAL-----PEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVF
120 130 140 150 160 170
170 180 190
pF1KE1 KPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
.:. :: : : . .. ... .. ..:
CCDS80 EPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
180 190 200 210
>>CCDS806.1 GSTM4 gene_id:2948|Hs108|chr1 (195 aa)
initn: 229 init1: 116 opt: 255 Z-score: 340.4 bits: 69.8 E(32554): 1.2e-12
Smith-Waterman score: 255; 30.0% identity (57.2% similar) in 180 aa overlap (6-174:5-181)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
: :...:: :. :: .. : : .::... ..: :. .: : : .
CCDS80 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQ
.: : .:: . :: :: :.... .: :.:: :. .:: . . : . . . .
CCDS80 LPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD
: :.. : : . : .:: .. .:: : :..:...:..:: .:.:. ::
CCDS80 DF-EKLKPEYLE-ELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
170 180 190
pF1KE1 NHPRLVTLRKKVQAIPAVANWIKRRPQTKL
: :
CCDS80 AFPNLKDFISRFEVSCGIM
180 190
>>CCDS4944.1 GSTA2 gene_id:2939|Hs108|chr6 (222 aa)
initn: 124 init1: 69 opt: 253 Z-score: 336.8 bits: 69.3 E(32554): 1.9e-12
Smith-Waterman score: 255; 26.5% identity (63.7% similar) in 204 aa overlap (5-195:6-206)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEV
:: : :.::: : ::...: ...:.. :..: : .... : : ..:..:.
CCDS49 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF---MSCFPWAE-KKQDVK
::. : :. :: :.... .: :. :. .: .. . :. . .:... ..::.:
CCDS49 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EQMFNELLTYNA--PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN
...: : : : . . : .. :...:.::... ::.. . . .:...
CCDS49 LALIQEK-TKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISS
130 140 150 160 170
180 190
pF1KE1 HPRLVTLRKKVQAIPAVANWIK----RRPQTKL
: : .:. ... .:.: .... :.:
CCDS49 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
180 190 200 210 220
>>CCDS44192.1 GSTM2 gene_id:2946|Hs108|chr1 (191 aa)
initn: 202 init1: 90 opt: 245 Z-score: 327.5 bits: 67.4 E(32554): 6.4e-12
Smith-Waterman score: 245; 30.4% identity (58.1% similar) in 191 aa overlap (1-174:1-181)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK
:: . : :.:.:: :. :: .. : : .::... ..: :. .: : : .
CCDS44 MP-MTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100
pF1KE1 IPILEVDGL-TLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDT-LDDFMS----CF-P
.: : .:: . :: :: ::.... .: :..: :: . : . . .:. :. :. :
CCDS44 LPYL-IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 WAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF
:: .: .... : :.... . .:: . :..:...:..:: ::
CCDS44 DFEK---LKPEYLQAL-----PEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVF
120 130 140 150 160 170
170 180 190
pF1KE1 KPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
.:. :: : :
CCDS44 EPSCLDAFPNLKDFISRFEHS
180 190
>>CCDS4947.1 GSTA3 gene_id:2940|Hs108|chr6 (222 aa)
initn: 150 init1: 75 opt: 245 Z-score: 326.4 bits: 67.4 E(32554): 7.4e-12
Smith-Waterman score: 247; 27.1% identity (60.5% similar) in 210 aa overlap (5-195:6-206)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEV
:: ::: ::: : ::...: ...:.. : .: : .... .: : ..:..:.
CCDS49 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMS-------CFPWAEKKQ
::. : :. :: :.... .: :. :. .: .. . :. : : ...
CCDS49 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP---EEK
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DVKEQMFNELL-TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDL-
:.: ...: . : . . :... :...:.::... :: : . :: . .:
CCDS49 DAKIALIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRAD----ISLVELLYYVEELD
120 130 140 150 160 170
170 180 190
pF1KE1 ---LDNHPRLVTLRKKVQAIPAVANWIK----RRPQTKL
..: : : .:. ... .:.: .... :.:
CCDS49 SSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
180 190 200 210 220
>>CCDS4945.1 GSTA1 gene_id:2938|Hs108|chr6 (222 aa)
initn: 126 init1: 71 opt: 242 Z-score: 322.5 bits: 66.7 E(32554): 1.2e-11
Smith-Waterman score: 245; 25.9% identity (60.0% similar) in 205 aa overlap (5-195:6-206)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEV
:: ::: ::: : :...: ...:.. :..: : .... : : ..:..:.
CCDS49 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF------MSCFPWAEKKQD
::. : :. :: :.... .: :. :. .: .. . :. . : :: :
CCDS49 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEK--D
70 80 90 100 110
120 130 140 150 160
pF1KE1 VKEQMFNELLTYNA-PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD
.: ...: . : . . : .. :...:.::... ::.. . . .:..
CCDS49 AKLALIKEKIKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLIS
120 130 140 150 160 170
170 180 190
pF1KE1 NHPRLVTLRKKVQAIPAVANWIK----RRPQTKL
. : : .:. ... .:.: .... :.:
CCDS49 SFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
180 190 200 210 220
>>CCDS4946.1 GSTA5 gene_id:221357|Hs108|chr6 (222 aa)
initn: 131 init1: 58 opt: 241 Z-score: 321.2 bits: 66.4 E(32554): 1.4e-11
Smith-Waterman score: 241; 25.2% identity (60.4% similar) in 202 aa overlap (5-198:6-205)
10 20 30 40 50
pF1KE1 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEV
:: : : :: : ::...: .. :.. .:.: : .... .: : ..:..:.
CCDS49 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVD----AIVDTLDDFMSCFPWAEKKQDVK
::. : :. :: :.... .: :. :. .: .::: . .. . ...:.:
CCDS49 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EQMFNELLTYNA-PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNH
. .: . : . . : .. ...:.::...:::.. . . .:...
CCDS49 TALVKEKIKNRYFPAFEKVLKSHR--QDYLVGNKLSWADIHLVELFYYVEELDSSLISSF
130 140 150 160 170
180 190
pF1KE1 PRLVTLRKKVQAIPAVANWIKRRPQTKL
: : .:. ... .:.: .... : :
CCDS49 PLLKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
180 190 200 210 220
199 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:23:43 2016 done: Sun Nov 6 17:23:43 2016
Total Scan time: 1.590 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]