Result of FASTA (omim) for
pFN21AE1674
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1674, 189 aa
1>>>pF1KE1674 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0699+/-0.000392; mu= 14.3805+/- 0.024
mean_var=65.3920+/-12.929, 0's: 0 Z-trim(112.3): 17 B-trim: 208 in 1/49
Lambda= 0.158603
statistics sampled from 21171 (21188) to 21171 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.248), width: 16
Scan time: 4.880
The best scores are: opt bits E(85289)
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1230 290.0 1.5e-78
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1135 268.3 5.2e-72
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1125 266.0 2.5e-71
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1125 266.0 2.5e-71
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1100 260.3 1.3e-69
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1079 255.5 3.8e-68
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1053 249.5 2.3e-66
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1026 243.4 1.7e-64
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 1006 238.8 4e-63
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 1001 237.6 8.9e-63
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1000 237.4 1e-62
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 996 236.5 2e-62
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 994 236.0 2.7e-62
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 692 166.9 1.7e-41
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 342 86.9 2.4e-17
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 310 79.5 3.5e-15
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 164 46.1 4.3e-05
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1230 init1: 1230 opt: 1230 Z-score: 1531.3 bits: 290.0 E(85289): 1.5e-78
Smith-Waterman score: 1230; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE1 FQERLRRKE
:::::::::
NP_002 FQERLRRKE
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1164 init1: 1135 opt: 1135 Z-score: 1413.8 bits: 268.3 E(85289): 5.2e-72
Smith-Waterman score: 1135; 92.1% identity (97.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
::.:::::.::::::::::::::::::::::::.::::.::::::::::::: :::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
:::::::::::::::: ::::::.::::::::::::::::::::::::::::::.:.:
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.:.:::::.
NP_066 LQKRLRRKD
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1170 init1: 1125 opt: 1125 Z-score: 1401.4 bits: 266.0 E(85289): 2.5e-71
Smith-Waterman score: 1125; 91.0% identity (97.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
.::::::::::::.:::::::::::::::::::.::::.::::::::::::: ::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
::::::::.::::::: ::::::.::::::::::::::::::::::::::::::.:.:
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.:. ::::.
NP_067 LQKILRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1154 init1: 1125 opt: 1125 Z-score: 1401.4 bits: 266.0 E(85289): 2.5e-71
Smith-Waterman score: 1125; 91.0% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
.::::::::::::::::::::::::::::::::.::::.::::::::::::: :::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
:::::::::::::::: ::::::.:::::::::: :.:::::::::::::::::.:.:
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.:.:::::.
NP_002 LQKRLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1100 init1: 1100 opt: 1100 Z-score: 1370.5 bits: 260.3 E(85289): 1.3e-69
Smith-Waterman score: 1100; 86.8% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:...:::::::::::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
::::::::::::::::::::::::::::::::::::::::...::.:: ::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
::..::::::.::::::::::.:.::::::::::::::::::::::::::::::::::
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.::::::::
NP_002 LQERLRRKE
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1113 init1: 1079 opt: 1079 Z-score: 1344.5 bits: 255.5 E(85289): 3.8e-68
Smith-Waterman score: 1079; 87.8% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:: ::::::.:::::::::::::::::::::: ::::::::::::::::::::::::.:
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
::.:::::.::::.:::::::::::::::::::.::::.::::::::::::: :::::::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
:::::::::::::::: : ::::.:::::::::: :::::::::::::::::::::.:
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
... ::::.
NP_066 LKKGLRRKD
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1074 init1: 1053 opt: 1053 Z-score: 1312.4 bits: 249.5 E(85289): 2.3e-66
Smith-Waterman score: 1053; 85.7% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::.:::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
:::: :::::::::::::..::::::::::::::::::.:...::.:: :: :::::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
::: ::::::: ::: ::::::.:::::::::: ::::::::::::::::::::.:
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.:. ::::.
NP_002 LQKGLRRKD
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1046 init1: 1026 opt: 1026 Z-score: 1279.0 bits: 243.4 E(85289): 1.7e-64
Smith-Waterman score: 1026; 82.0% identity (93.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::::::::::::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
:::::::::::::::::::::::.::::::::::.:::.:...::::: :: ::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
:::::::::::::::: ::::::::::::::::: :::::::::::::::::::.:.:
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.:.:::::.
NP_002 LQKRLRRKD
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1006 init1: 1006 opt: 1006 Z-score: 1254.2 bits: 238.8 E(85289): 4e-63
Smith-Waterman score: 1006; 81.5% identity (91.5% similar) in 189 aa overlap (1-189:2-190)
10 20 30 40 50
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDF
:: :.::::..::: :: ::::::::.:::: :::.:.:::::.:::: ::: :::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDL
::::::::::::::: :::::::.::: ::::.::::::.:...::.:: ::: ::::::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSK
::::.:: : ::::::.::::::::::.::::::::::::::::::::::::::.:::
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KE1 IFQERLRRKE
.::::::::
NP_008 NLQERLRRKE
190
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 1001 init1: 1001 opt: 1001 Z-score: 1248.1 bits: 237.6 E(85289): 8.9e-63
Smith-Waterman score: 1001; 81.0% identity (91.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.:::: ::: ::::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
:::::::::::::: :::::::.::: ::::.::::::.:...::.:: ::: :::::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
:::.:: : ::::::.::::::::::.::::::::::::::::::::::::::.:::
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
pF1KE1 FQERLRRKE
.::::::::
NP_076 LQERLRRKE
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:50:17 2016 done: Sun Nov 6 15:50:17 2016
Total Scan time: 4.880 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]