Result of FASTA (omim) for
pFN21AE1673
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1673, 189 aa
1>>>pF1KE1673 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2969+/-0.000388; mu= 12.9919+/- 0.024
mean_var=67.0043+/-13.076, 0's: 0 Z-trim(112.6): 17 B-trim: 0 in 0/51
Lambda= 0.156683
statistics sampled from 21512 (21529) to 21512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.252), width: 16
Scan time: 5.650
The best scores are: opt bits E(85289)
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1233 287.4 9e-78
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1177 274.8 5.8e-74
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1176 274.6 6.8e-74
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1140 266.4 1.9e-71
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1125 263.0 2e-70
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1081 253.1 2e-67
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1072 251.1 8.1e-67
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1058 247.9 7.3e-66
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1005 235.9 2.9e-62
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 991 232.7 2.6e-61
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 990 232.5 3.1e-61
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 988 232.1 4.2e-61
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 985 231.4 6.8e-61
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 725 172.6 3.4e-43
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 361 90.4 2.1e-18
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 325 82.2 5.5e-16
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 163 45.6 6.3e-05
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1233 init1: 1233 opt: 1233 Z-score: 1517.2 bits: 287.4 E(85289): 9e-78
Smith-Waterman score: 1233; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
:::::::::
NP_002 LQKRLRRKD
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1177 init1: 1177 opt: 1177 Z-score: 1448.8 bits: 274.8 E(85289): 5.8e-74
Smith-Waterman score: 1177; 95.8% identity (98.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
:::::::::::::::::::::::::::::::::::::::::.:::::: ::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:.:::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::::::::::::::::::: :.:::::::::::::::::::::::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
:::::::::
NP_066 LQKRLRRKD
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1176 init1: 1176 opt: 1176 Z-score: 1447.6 bits: 274.6 E(85289): 6.8e-74
Smith-Waterman score: 1176; 95.2% identity (98.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
:::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.::::::::::::.:::::::::::::::::::::::::::::::::::::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
::::::::.::::::::::::::::::::::::: :.:::::::::::::::::::::::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
::: :::::
NP_067 LQKILRRKD
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1140 init1: 1140 opt: 1140 Z-score: 1403.6 bits: 266.4 E(85289): 1.9e-71
Smith-Waterman score: 1140; 92.1% identity (97.9% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
:: ::::::.:::::::::::::::::::::: ::::::::.:::::::::::::::.::
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:.:::::.::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::: :::::::::::::::.:.:::::::::::::::::.:::::
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
:.: :::::
NP_066 LKKGLRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1162 init1: 1125 opt: 1125 Z-score: 1385.3 bits: 263.0 E(85289): 2e-70
Smith-Waterman score: 1125; 91.0% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
:::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.::::::::::::::::::::::::::::::::.::::.::::::::::::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::: ::::::.:::::::::: :.:::::::::::::::::.:.:
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
.:.:::::.
NP_002 FQERLRRKE
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1081 init1: 1081 opt: 1081 Z-score: 1331.6 bits: 253.1 E(85289): 2e-67
Smith-Waterman score: 1081; 87.3% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
:::::::::::::::::::::::::::::::::::::::::.:::::: :::::::.::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.::: :::::::::::::..:::::::::::::.::::::...::.:: ::.:::::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
::: ::::::: :::::::::::::::::::::. .:::::::::::::::::.:::::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
::: :::::
NP_002 LQKGLRRKD
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1072 init1: 1072 opt: 1072 Z-score: 1320.6 bits: 251.1 E(85289): 8.1e-67
Smith-Waterman score: 1072; 84.1% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
::: :.:.::..::: :: :::::.: :::::.:::.:.:..:: ::::::::::::::.
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.::::::::::::::::::::::.:::::::::..:::::...::::: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::::::::.::::::::::.:.:::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
:::::::::
NP_002 LQKRLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1073 init1: 1058 opt: 1058 Z-score: 1303.5 bits: 247.9 E(85289): 7.3e-66
Smith-Waterman score: 1058; 82.5% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
::: : ::::..::. ::::::::::::::::.:::.:....:::::::::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.::::::::::::::::::::::::::::::::.::::.:...::.:: :::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
::..::::::.::::: ::::.:::::::::::: :.:::::::::::::::::.:.:.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
::.:::::.
NP_002 LQERLRRKE
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1020 init1: 1005 opt: 1005 Z-score: 1238.7 bits: 235.9 E(85289): 2.9e-62
Smith-Waterman score: 1005; 81.0% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
::: :.::::..::: :: ::: ::::::::::.::...::.:: ::: :::::::::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:::::::::::::.:::::::.::::::::::.:::.::.. ::.:. :::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
:::.::: : ::::::::::::::::::::::: :.:::::::::::::::::.: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
::.:::::.
NP_066 LQERLRRKE
>>NP_002161 (OMIM: 147568) interferon alpha-8 precursor (189 aa)
initn: 1012 init1: 991 opt: 991 Z-score: 1221.6 bits: 232.7 E(85289): 2.6e-61
Smith-Waterman score: 991; 80.4% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
:::.: ::.:..::::::. :::::::::::::::::::::.:: ::::::::::::::.
NP_002 MALTFYLLVALVVLSYKSFSSLGCDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:::::: .::::::::::::::::::::::::.::::: ...::..: :: :::::::
NP_002 FPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
.::.::::: :.::: :::::::::::::::::: :.::: :::::::::::::.:.: :
NP_002 SCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSIN
130 140 150 160 170 180
pF1KE1 LQKRLRRKD
:::::. :.
NP_002 LQKRLKSKE
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:50:34 2016 done: Sun Nov 6 05:50:35 2016
Total Scan time: 5.650 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]