Result of FASTA (omim) for
pFN21AE1672
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1672, 189 aa
1>>>pF1KE1672 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9868+/-0.000367; mu= 14.5991+/- 0.023
mean_var=60.1565+/-11.900, 0's: 0 Z-trim(113.3): 35 B-trim: 96 in 1/51
Lambda= 0.165361
statistics sampled from 22586 (22613) to 22586 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.265), width: 16
Scan time: 5.590
The best scores are: opt bits E(85289)
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1258 308.3 4.8e-84
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1074 264.4 7.9e-71
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1052 259.1 3e-69
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 1043 257.0 1.3e-68
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 1042 256.7 1.6e-68
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 1037 255.5 3.6e-68
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1007 248.4 5.1e-66
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1005 247.9 7.2e-66
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1000 246.7 1.6e-65
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 984 242.9 2.3e-64
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 975 240.8 1e-63
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 964 238.1 6.3e-63
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 959 236.9 1.4e-62
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 683 171.1 9.8e-43
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 345 90.5 1.9e-18
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 308 81.6 8.1e-16
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 159 46.1 4.4e-05
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1258 init1: 1258 opt: 1258 Z-score: 1629.8 bits: 308.3 E(85289): 4.8e-84
Smith-Waterman score: 1258; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
:::::::::
NP_066 LQERLRRKE
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1074 init1: 1074 opt: 1074 Z-score: 1392.5 bits: 264.4 E(85289): 7.9e-71
Smith-Waterman score: 1074; 86.2% identity (93.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
:::::.::::::::.::: ::: :::::::::..:::.:..::: ::: ::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
::::::::::::::.:::::::.::::::::::::::..::: ::::.::::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
::.:::: : ::::: ::::.:::::::::::::::::::::::::::::::::: : :
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
:::::::::
NP_002 LQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1104 init1: 1052 opt: 1052 Z-score: 1364.2 bits: 259.1 E(85289): 3e-69
Smith-Waterman score: 1052; 83.1% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
:::::::.:::::::::::::: :.: :::::..:::.::.::::::: ::::::::::.
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
::::::::::::::.:::::::..::::::::::.::.:::: ::.:.: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::.::: : ::::::::::::.:::::::::: :::::::::::::::::::.: : :
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::.:::::.
NP_002 LQKRLRRKD
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 1041 init1: 660 opt: 1043 Z-score: 1352.6 bits: 257.0 E(85289): 1.3e-68
Smith-Waterman score: 1043; 85.7% identity (91.0% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
::: ::::.::.:::::::::. :::::::::: :::.:::::::::::::::::::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
:::::: ::::::::.: ::::.::: ::::::::::.:::: ::::.::::::::::::
NP_000 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::.: : : ::::.:::::::::::::::::: ::::::::::::::::::::: : :
NP_000 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
120 130 140 150 160 170
pF1KE1 LQERLRRKE
::: :: ::
NP_000 LQESLRSKE
180
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1042 init1: 1042 opt: 1042 Z-score: 1351.3 bits: 256.7 E(85289): 1.6e-68
Smith-Waterman score: 1042; 85.2% identity (90.5% similar) in 189 aa overlap (1-189:2-190)
10 20 30 40 50
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDF
:: ::::::::::::::::::: ::::.:::: .:::.:::::: ::: ::: :::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 RFPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDL
:::::::::::::: :::::::.::: ::::.:::::.:::: ::::. ::::::::::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSR
::::::: :: ::::: ::::::.:::.::::::::::::::::::::::::::.: :
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KE1 NLQERLRRKE
::::::::::
NP_008 NLQERLRRKE
190
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 1037 init1: 1037 opt: 1037 Z-score: 1344.8 bits: 255.5 E(85289): 3.6e-68
Smith-Waterman score: 1037; 84.7% identity (90.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
:: ::::::.:::::::::::: ::::.:::: .:::.:::::: ::: ::: :::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
:::::::::::::: :::::::.::: ::::.:::::.:::: ::::. :::::::::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::::: :: ::::: ::::::.:::.::::::::::::::::::::::::::.: : :
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
:::::::::
NP_076 LQERLRRKE
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1022 init1: 1007 opt: 1007 Z-score: 1306.2 bits: 248.4 E(85289): 5.1e-66
Smith-Waterman score: 1007; 81.5% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
::: :.::::..::: :: ::: ::::::::::.::...::::: ::: ::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
::.:::::.:::::.:::::::.::::::::::.:::.::.. ::.:. :::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::.::: : :::::::::::::::::::::::::::::::::::::::::::.: : :
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::.:::::.
NP_066 LQKRLRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1020 init1: 1005 opt: 1005 Z-score: 1303.6 bits: 247.9 E(85289): 7.2e-66
Smith-Waterman score: 1005; 81.0% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
::: :.::::..::: :: ::: ::::::::::.::...::.:: ::: :::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
.:::::::::::::.:::::::.::::::::::.:::.::.. ::.:. :::::::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::.::: : ::::::::::::::::::::::: :.:::::::::::::::::.: : :
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::.:::::.
NP_002 LQKRLRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1000 init1: 1000 opt: 1000 Z-score: 1297.1 bits: 246.7 E(85289): 1.6e-65
Smith-Waterman score: 1000; 81.5% identity (91.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
::: :.::::..::: :: ::: ::::::::::.::...::::: ::: ::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
::::::::::::::.:::::::.::::::::::::::..:.. ::.:. ::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::.::: : ::::: ::::::.:::::::::::::::::::::::::::::::: :.
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE1 LQERLRRKE
.::::::::
NP_002 FQERLRRKE
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 999 init1: 984 opt: 984 Z-score: 1276.5 bits: 242.9 E(85289): 2.3e-64
Smith-Waterman score: 984; 79.9% identity (92.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
::: :.::::..::: :: ::: ::::::::::.::...::::: ::: ::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
.::::::::::::..:::::::.::::::::::.:::.::.. ::.:. ::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
:::.::: . :::::::::::::::::::::::::::::::::::::::::::.: : :
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::. ::::.
NP_067 LQKILRRKD
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:49:20 2016 done: Sun Nov 6 15:49:21 2016
Total Scan time: 5.590 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]