Result of FASTA (omim) for
pFN21AE1662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1662, 180 aa
1>>>pF1KE1662 180 - 180 aa - 180 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7940+/-0.000235; mu= 12.6906+/- 0.015
mean_var=90.1615+/-17.927, 0's: 0 Z-trim(124.3): 15 B-trim: 0 in 0/61
Lambda= 0.135072
statistics sampled from 45818 (45833) to 45818 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.848), E-opt: 0.2 (0.537), width: 16
Scan time: 6.150
The best scores are: opt bits E(85289)
NP_055258 (OMIM: 604627) interleukin-17B isoform 1 ( 180) 1283 258.4 4.6e-69
XP_016864835 (OMIM: 604627) PREDICTED: interleukin ( 245) 1221 246.4 2.5e-65
XP_011535924 (OMIM: 604627) PREDICTED: interleukin ( 128) 912 186.0 2e-47
XP_016864836 (OMIM: 604627) PREDICTED: interleukin ( 128) 912 186.0 2e-47
NP_001304916 (OMIM: 604627) interleukin-17B isofor ( 128) 912 186.0 2e-47
XP_016864837 (OMIM: 604627) PREDICTED: interleukin ( 128) 912 186.0 2e-47
XP_005266478 (OMIM: 607587) PREDICTED: interleukin ( 209) 256 58.3 9e-09
NP_612141 (OMIM: 607587) interleukin-17D precursor ( 202) 254 57.9 1.1e-08
NP_037410 (OMIM: 604628) interleukin-17C precursor ( 197) 201 47.6 1.4e-05
NP_443104 (OMIM: 606496,613956) interleukin-17F pr ( 163) 199 47.1 1.6e-05
XP_011512578 (OMIM: 606496,613956) PREDICTED: inte ( 163) 199 47.1 1.6e-05
NP_002181 (OMIM: 603149) interleukin-17A precursor ( 155) 198 46.9 1.8e-05
XP_005266479 (OMIM: 607587) PREDICTED: interleukin ( 114) 187 44.7 6.2e-05
NP_758525 (OMIM: 605658) interleukin-25 isoform 2 ( 161) 177 42.8 0.00032
NP_073626 (OMIM: 605658) interleukin-25 isoform 1 ( 177) 177 42.9 0.00034
>>NP_055258 (OMIM: 604627) interleukin-17B isoform 1 pre (180 aa)
initn: 1283 init1: 1283 opt: 1283 Z-score: 1361.0 bits: 258.4 E(85289): 4.6e-69
Smith-Waterman score: 1283; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KE1 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
130 140 150 160 170 180
>>XP_016864835 (OMIM: 604627) PREDICTED: interleukin-17B (245 aa)
initn: 1221 init1: 1221 opt: 1221 Z-score: 1293.8 bits: 246.4 E(85289): 2.5e-65
Smith-Waterman score: 1221; 100.0% identity (100.0% similar) in 173 aa overlap (8-180:73-245)
10 20 30
pF1KE1 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGP
::::::::::::::::::::::::::::::
XP_016 VKLTCSHTVSESGDHPRRESAVSGRPGQSALFLLTISIFLGLGQPRSPKSKRKGQGRPGP
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE1 LAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRS
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE1 LSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPP
170 180 190 200 210 220
160 170 180
pF1KE1 PRTGPCRQRAVMETIAVGCTCIF
:::::::::::::::::::::::
XP_016 PRTGPCRQRAVMETIAVGCTCIF
230 240
>>XP_011535924 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 912 init1: 912 opt: 912 Z-score: 972.3 bits: 186.0 E(85289): 2e-47
Smith-Waterman score: 912; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KE1 RSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQR
::::::::::::::::::::::::::::::
XP_011 MKPYARMEEYERNIEEMVAQLRNSSELAQR
10 20 30
90 100 110 120 130 140
pF1KE1 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
40 50 60 70 80 90
150 160 170 180
pF1KE1 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
::::::::::::::::::::::::::::::::::::::
XP_011 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
100 110 120
>>XP_016864836 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 912 init1: 912 opt: 912 Z-score: 972.3 bits: 186.0 E(85289): 2e-47
Smith-Waterman score: 912; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KE1 RSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQR
::::::::::::::::::::::::::::::
XP_016 MKPYARMEEYERNIEEMVAQLRNSSELAQR
10 20 30
90 100 110 120 130 140
pF1KE1 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
40 50 60 70 80 90
150 160 170 180
pF1KE1 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
::::::::::::::::::::::::::::::::::::::
XP_016 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
100 110 120
>>NP_001304916 (OMIM: 604627) interleukin-17B isoform 2 (128 aa)
initn: 912 init1: 912 opt: 912 Z-score: 972.3 bits: 186.0 E(85289): 2e-47
Smith-Waterman score: 912; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KE1 RSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQR
::::::::::::::::::::::::::::::
NP_001 MKPYARMEEYERNIEEMVAQLRNSSELAQR
10 20 30
90 100 110 120 130 140
pF1KE1 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
40 50 60 70 80 90
150 160 170 180
pF1KE1 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
::::::::::::::::::::::::::::::::::::::
NP_001 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
100 110 120
>>XP_016864837 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 912 init1: 912 opt: 912 Z-score: 972.3 bits: 186.0 E(85289): 2e-47
Smith-Waterman score: 912; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KE1 RSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQR
::::::::::::::::::::::::::::::
XP_016 MKPYARMEEYERNIEEMVAQLRNSSELAQR
10 20 30
90 100 110 120 130 140
pF1KE1 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVP
40 50 60 70 80 90
150 160 170 180
pF1KE1 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
::::::::::::::::::::::::::::::::::::::
XP_016 VFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
100 110 120
>>XP_005266478 (OMIM: 607587) PREDICTED: interleukin-17D (209 aa)
initn: 275 init1: 205 opt: 256 Z-score: 278.5 bits: 58.3 E(85289): 9e-09
Smith-Waterman score: 256; 31.6% identity (58.2% similar) in 177 aa overlap (7-179:5-177)
10 20 30 40 50
pF1KE1 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQ--GRPGPLAPGPHQVPLDLVSRMKPYAR
:...:. ...:.: . . : :. .:: : :... .: .:. .
XP_005 MLGALVWMLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQLYGRLAA-GV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 MEEYERNIEEMV-AQLRNSSELAQ-RKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDL
. ...... : ::.: : : . .. .: ::.:::.: :..::.: : :
XP_005 LSAFHHTLQLGPREQARNASCPAGGRPADRRFRP-PTNLRSVSPWAYRISYDPARYPRYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 PEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGC
::: ::: ::.. . .:: . :.::. . : :: : : .. :: :::
XP_005 PEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRR--TPACAGGRSVYTEAYVTIPVGC
120 130 140 150 160 170
180
pF1KE1 TCIF
::.
XP_005 TCVPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP
180 190 200
>>NP_612141 (OMIM: 607587) interleukin-17D precursor [Ho (202 aa)
initn: 275 init1: 205 opt: 254 Z-score: 276.6 bits: 57.9 E(85289): 1.1e-08
Smith-Waterman score: 254; 32.9% identity (57.2% similar) in 173 aa overlap (9-179:6-170)
10 20 30 40 50 60
pF1KE1 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARME
:::.. . : ::. ..: . :: : :... .: .:. . .
NP_612 MLVAGFLLALPPSWAAGAPRA--GRRPA--RPRGCADRPEELLEQLYGRLAAGV-LS
10 20 30 40 50
70 80 90 100 110
pF1KE1 EYERNIEEMV-AQLRNSSELAQ-RKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPE
...... : ::.: : : . .. .: ::.:::.: :..::.: : :::
NP_612 AFHHTLQLGPREQARNASCPAGGRPADRRFRP-PTNLRSVSPWAYRISYDPARYPRYLPE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 ARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTC
: ::: ::.. . .:: . :.::. . : :: : : .. :: :::::
NP_612 AYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRR--TPACAGGRSVYTEAYVTIPVGCTC
120 130 140 150 160
180
pF1KE1 IF
.
NP_612 VPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP
170 180 190 200
>>NP_037410 (OMIM: 604628) interleukin-17C precursor [Ho (197 aa)
initn: 197 init1: 162 opt: 201 Z-score: 220.9 bits: 47.6 E(85289): 1.4e-05
Smith-Waterman score: 205; 30.2% identity (54.1% similar) in 159 aa overlap (31-180:45-193)
10 20 30 40 50
pF1KE1 MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGP---HQVPLDLVSRMKPYA
::. : :: : . .:. ::: .. .
NP_037 TCLAHHDPSLRGHPHSHGTPHCYSAEELPLGQAPPHLLARGAKWGQALPVALVSSLEAAS
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 RMEEYER-NIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDL
. ..:: . . :: : :.. ...::.::: : .. : .: : :
NP_037 HRGRHERPSATTQCPVLRPEEVL-----EAD-----THQRSISPWRYRVDTDEDRYPQKL
80 90 100 110 120
120 130 140 150 160 170
pF1KE1 PEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPV-RRRLCPPP----PRTGPCRQRAVMET
:.::: ::.. : .: .. :: ..... : ::: : : : .. .
NP_037 AFAECLCRGCIDARTGRETAALNSVRLLQSLLVLRRRPCSRDGSGLPTPGAFAFHTEFIH
130 140 150 160 170 180
180
pF1KE1 IAVGCTCIF
. :::::..
NP_037 VPVGCTCVLPRSV
190
>>NP_443104 (OMIM: 606496,613956) interleukin-17F precur (163 aa)
initn: 213 init1: 138 opt: 199 Z-score: 220.0 bits: 47.1 E(85289): 1.6e-05
Smith-Waterman score: 199; 38.4% identity (61.6% similar) in 86 aa overlap (96-179:77-155)
70 80 90 100 110 120
pF1KE1 IEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLG
:: :::.:... ::.: : .. .:.: ::
NP_443 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 CVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETI--AVGCTCIF
:.: .:: :: :::. ... : :: . : .: . .:::::.
NP_443 CINA-QGKEDISMNSVPIQQETLVVRR------KHQGCSVSFQLEKVLVTVGCTCVTPVI
110 120 130 140 150
NP_443 HHVQ
160
180 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:04:55 2016 done: Sun Nov 6 17:04:56 2016
Total Scan time: 6.150 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]