Result of FASTA (omim) for
pFN21AE1660
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1660, 177 aa
1>>>pF1KE1660 177 - 177 aa - 177 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7251+/-0.000255; mu= 11.6656+/- 0.016
mean_var=83.7404+/-16.459, 0's: 0 Z-trim(121.7): 15 B-trim: 0 in 0/58
Lambda= 0.140154
statistics sampled from 38615 (38635) to 38615 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.453), width: 16
Scan time: 5.660
The best scores are: opt bits E(85289)
NP_073626 (OMIM: 605658) interleukin-25 isoform 1 ( 177) 1285 268.4 4.3e-72
NP_758525 (OMIM: 605658) interleukin-25 isoform 2 ( 161) 1171 245.3 3.5e-65
NP_037410 (OMIM: 604628) interleukin-17C precursor ( 197) 223 53.7 2.1e-07
NP_612141 (OMIM: 607587) interleukin-17D precursor ( 202) 181 45.2 7.6e-05
XP_005266478 (OMIM: 607587) PREDICTED: interleukin ( 209) 181 45.2 7.8e-05
XP_016864837 (OMIM: 604627) PREDICTED: interleukin ( 128) 177 44.3 9.2e-05
XP_011535924 (OMIM: 604627) PREDICTED: interleukin ( 128) 177 44.3 9.2e-05
NP_001304916 (OMIM: 604627) interleukin-17B isofor ( 128) 177 44.3 9.2e-05
XP_016864836 (OMIM: 604627) PREDICTED: interleukin ( 128) 177 44.3 9.2e-05
NP_055258 (OMIM: 604627) interleukin-17B isoform 1 ( 180) 177 44.4 0.00012
XP_016864835 (OMIM: 604627) PREDICTED: interleukin ( 245) 177 44.4 0.00015
XP_011512578 (OMIM: 606496,613956) PREDICTED: inte ( 163) 159 40.7 0.0014
NP_443104 (OMIM: 606496,613956) interleukin-17F pr ( 163) 159 40.7 0.0014
>>NP_073626 (OMIM: 605658) interleukin-25 isoform 1 prec (177 aa)
initn: 1285 init1: 1285 opt: 1285 Z-score: 1415.3 bits: 268.4 E(85289): 4.3e-72
Smith-Waterman score: 1285; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)
10 20 30 40 50 60
pF1KE1 MRERPRLGEDSSLISLFLQVVAFLAMVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MRERPRLGEDSSLISLFLQVVAFLAMVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQT
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 GSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG
130 140 150 160 170
>>NP_758525 (OMIM: 605658) interleukin-25 isoform 2 prec (161 aa)
initn: 1171 init1: 1171 opt: 1171 Z-score: 1291.3 bits: 245.3 E(85289): 3.5e-65
Smith-Waterman score: 1171; 100.0% identity (100.0% similar) in 159 aa overlap (19-177:3-161)
10 20 30 40 50 60
pF1KE1 MRERPRLGEDSSLISLFLQVVAFLAMVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVP
::::::::::::::::::::::::::::::::::::::::::
NP_758 MYQVVAFLAMVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVP
10 20 30 40
70 80 90 100 110 120
pF1KE1 PLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 PLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQT
50 60 70 80 90 100
130 140 150 160 170
pF1KE1 GSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 GSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG
110 120 130 140 150 160
>>NP_037410 (OMIM: 604628) interleukin-17C precursor [Ho (197 aa)
initn: 199 init1: 159 opt: 223 Z-score: 254.1 bits: 53.7 E(85289): 2.1e-07
Smith-Waterman score: 230; 32.9% identity (54.7% similar) in 170 aa overlap (31-174:27-195)
10 20 30 40 50
pF1KE1 MRERPRLGEDSSLISLFLQVVAFLAMVMGTHTYSHW-PSCCPSK----GQDTSEELLR--
: .:: : : .. :: . : :
NP_037 MTLLPGLLFLTWLHTCLAHHDPSLRGHPHSHGTPHCYSAEELPLGQAPPHLLARGA
10 20 30 40 50
60 70 80 90
pF1KE1 -WS-TVPVP---PLEPARP-NRH--PES---C---RASE--DGPLNSRAISPWRYELDRD
:. ..:: :: : .:: : . : : : .. ..:.::::::..: :
NP_037 KWGQALPVALVSSLEAASHRGRHERPSATTQCPVLRPEEVLEADTHQRSISPWRYRVDTD
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE1 LNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKG---THKG
.: :: : :.::: :.. .:: . :: : .. :. :::: . . : .
NP_037 EDRYPQKLAFAECLCRGCIDARTGRETAAL-NSVRLLQSLLVLRRRPCSRDGSGLPTPGA
120 130 140 150 160 170
160 170
pF1KE1 YCLERRLYRVSLACVCVRPRVMG
. .. .. .: ..:.:: ::
NP_037 FAFHTEFIHVPVGCTCVLPRSV
180 190
>>NP_612141 (OMIM: 607587) interleukin-17D precursor [Ho (202 aa)
initn: 134 init1: 116 opt: 181 Z-score: 208.0 bits: 45.2 E(85289): 7.6e-05
Smith-Waterman score: 181; 30.0% identity (52.5% similar) in 120 aa overlap (56-171:57-170)
30 40 50 60 70 80
pF1KE1 MVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVPPLEPARPNRHPESCRASED---GPL
:. . : : :: : . : .. :
NP_612 RPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQLGPREQARNASCPAGGRPADRRFRPPT
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE1 NSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYR
: :..::: :... : : :. : .: ::: :.. : . : : : .: .:. :
NP_612 NLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEE-DVRFRSAPVYMPTVVLRR
90 100 110 120 130 140
150 160 170
pF1KE1 RP-CHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG
: : : .... . . ..:.::
NP_612 TPACAGGRSVYT-----EAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPA
150 160 170 180 190 200
>>XP_005266478 (OMIM: 607587) PREDICTED: interleukin-17D (209 aa)
initn: 134 init1: 116 opt: 181 Z-score: 207.8 bits: 45.2 E(85289): 7.8e-05
Smith-Waterman score: 181; 30.0% identity (52.5% similar) in 120 aa overlap (56-171:64-177)
30 40 50 60 70 80
pF1KE1 MVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVPPLEPARPNRHPESCRASED---GPL
:. . : : :: : . : .. :
XP_005 RPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQLGPREQARNASCPAGGRPADRRFRPPT
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE1 NSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYR
: :..::: :... : : :. : .: ::: :.. : . : : : .: .:. :
XP_005 NLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEE-DVRFRSAPVYMPTVVLRR
100 110 120 130 140 150
150 160 170
pF1KE1 RP-CHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG
: : : .... . . ..:.::
XP_005 TPACAGGRSVYT-----EAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPA
160 170 180 190 200
>>XP_016864837 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 125 init1: 125 opt: 177 Z-score: 206.5 bits: 44.3 E(85289): 9.2e-05
Smith-Waterman score: 177; 33.3% identity (62.2% similar) in 90 aa overlap (83-171:42-127)
60 70 80 90 100 110
pF1KE1 RWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLC
:.:..::: : ...: .:.: :: .:::::
XP_016 RNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLC
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 PHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYR-VSLACVCV
::. : .. :. . .:. :: : : : : .: ... ....:.:.
XP_016 LGCVNPFT--MQEDRSMVSVPVFSQVPVRRRLCPPPPRT--GPCRQRAVMETIAVGCTCI
80 90 100 110 120
pF1KE1 RPRVMG
XP_016 F
>>XP_011535924 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 125 init1: 125 opt: 177 Z-score: 206.5 bits: 44.3 E(85289): 9.2e-05
Smith-Waterman score: 177; 33.3% identity (62.2% similar) in 90 aa overlap (83-171:42-127)
60 70 80 90 100 110
pF1KE1 RWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLC
:.:..::: : ...: .:.: :: .:::::
XP_011 RNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLC
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 PHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYR-VSLACVCV
::. : .. :. . .:. :: : : : : .: ... ....:.:.
XP_011 LGCVNPFT--MQEDRSMVSVPVFSQVPVRRRLCPPPPRT--GPCRQRAVMETIAVGCTCI
80 90 100 110 120
pF1KE1 RPRVMG
XP_011 F
>>NP_001304916 (OMIM: 604627) interleukin-17B isoform 2 (128 aa)
initn: 125 init1: 125 opt: 177 Z-score: 206.5 bits: 44.3 E(85289): 9.2e-05
Smith-Waterman score: 177; 33.3% identity (62.2% similar) in 90 aa overlap (83-171:42-127)
60 70 80 90 100 110
pF1KE1 RWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLC
:.:..::: : ...: .:.: :: .:::::
NP_001 RNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLC
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 PHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYR-VSLACVCV
::. : .. :. . .:. :: : : : : .: ... ....:.:.
NP_001 LGCVNPFT--MQEDRSMVSVPVFSQVPVRRRLCPPPPRT--GPCRQRAVMETIAVGCTCI
80 90 100 110 120
pF1KE1 RPRVMG
NP_001 F
>>XP_016864836 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 125 init1: 125 opt: 177 Z-score: 206.5 bits: 44.3 E(85289): 9.2e-05
Smith-Waterman score: 177; 33.3% identity (62.2% similar) in 90 aa overlap (83-171:42-127)
60 70 80 90 100 110
pF1KE1 RWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLC
:.:..::: : ...: .:.: :: .:::::
XP_016 RNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLC
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 PHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYR-VSLACVCV
::. : .. :. . .:. :: : : : : .: ... ....:.:.
XP_016 LGCVNPFT--MQEDRSMVSVPVFSQVPVRRRLCPPPPRT--GPCRQRAVMETIAVGCTCI
80 90 100 110 120
pF1KE1 RPRVMG
XP_016 F
>>NP_055258 (OMIM: 604627) interleukin-17B isoform 1 pre (180 aa)
initn: 125 init1: 125 opt: 177 Z-score: 204.4 bits: 44.4 E(85289): 0.00012
Smith-Waterman score: 177; 33.3% identity (62.2% similar) in 90 aa overlap (83-171:94-179)
60 70 80 90 100 110
pF1KE1 RWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLC
:.:..::: : ...: .:.: :: .:::::
NP_055 RNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 PHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYR-VSLACVCV
::. : .. :. . .:. :: : : : : .: ... ....:.:.
NP_055 LGCVNPFT--MQEDRSMVSVPVFSQVPVRRRLCPPPPRT--GPCRQRAVMETIAVGCTCI
130 140 150 160 170
pF1KE1 RPRVMG
NP_055 F
180
177 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:30:20 2016 done: Sun Nov 6 14:30:21 2016
Total Scan time: 5.660 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]