Result of FASTA (omim) for
pFN21AE1647
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1647, 163 aa
1>>>pF1KE1647 163 - 163 aa - 163 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2973+/-0.000289; mu= 12.3214+/- 0.018
mean_var=64.4879+/-12.741, 0's: 0 Z-trim(118.2): 16 B-trim: 816 in 1/54
Lambda= 0.159711
statistics sampled from 30955 (30971) to 30955 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.363), width: 16
Scan time: 4.870
The best scores are: opt bits E(85289)
XP_011512578 (OMIM: 606496,613956) PREDICTED: inte ( 163) 1102 261.9 3.4e-70
NP_443104 (OMIM: 606496,613956) interleukin-17F pr ( 163) 1102 261.9 3.4e-70
NP_002181 (OMIM: 603149) interleukin-17A precursor ( 155) 431 107.2 1.1e-23
NP_612141 (OMIM: 607587) interleukin-17D precursor ( 202) 216 57.8 1.2e-08
XP_005266478 (OMIM: 607587) PREDICTED: interleukin ( 209) 216 57.8 1.2e-08
XP_016864836 (OMIM: 604627) PREDICTED: interleukin ( 128) 199 53.7 1.2e-07
XP_011535924 (OMIM: 604627) PREDICTED: interleukin ( 128) 199 53.7 1.2e-07
NP_001304916 (OMIM: 604627) interleukin-17B isofor ( 128) 199 53.7 1.2e-07
XP_016864837 (OMIM: 604627) PREDICTED: interleukin ( 128) 199 53.7 1.2e-07
NP_055258 (OMIM: 604627) interleukin-17B isoform 1 ( 180) 199 53.8 1.6e-07
XP_016864835 (OMIM: 604627) PREDICTED: interleukin ( 245) 199 53.9 2.1e-07
NP_037410 (OMIM: 604628) interleukin-17C precursor ( 197) 183 50.1 2.2e-06
XP_005266479 (OMIM: 607587) PREDICTED: interleukin ( 114) 168 46.6 1.5e-05
NP_758525 (OMIM: 605658) interleukin-25 isoform 2 ( 161) 159 44.6 8.6e-05
NP_073626 (OMIM: 605658) interleukin-25 isoform 1 ( 177) 159 44.6 9.3e-05
>>XP_011512578 (OMIM: 606496,613956) PREDICTED: interleu (163 aa)
initn: 1102 init1: 1102 opt: 1102 Z-score: 1381.2 bits: 261.9 E(85289): 3.4e-70
Smith-Waterman score: 1102; 100.0% identity (100.0% similar) in 163 aa overlap (1-163:1-163)
10 20 30 40 50 60
pF1KE1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS
70 80 90 100 110 120
130 140 150 160
pF1KE1 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
:::::::::::::::::::::::::::::::::::::::::::
XP_011 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
130 140 150 160
>>NP_443104 (OMIM: 606496,613956) interleukin-17F precur (163 aa)
initn: 1102 init1: 1102 opt: 1102 Z-score: 1381.2 bits: 261.9 E(85289): 3.4e-70
Smith-Waterman score: 1102; 100.0% identity (100.0% similar) in 163 aa overlap (1-163:1-163)
10 20 30 40 50 60
pF1KE1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS
70 80 90 100 110 120
130 140 150 160
pF1KE1 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
:::::::::::::::::::::::::::::::::::::::::::
NP_443 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
130 140 150 160
>>NP_002181 (OMIM: 603149) interleukin-17A precursor [Ho (155 aa)
initn: 411 init1: 411 opt: 431 Z-score: 546.0 bits: 107.2 E(85289): 1.1e-23
Smith-Waterman score: 431; 49.0% identity (68.2% similar) in 151 aa overlap (18-162:7-154)
10 20 30 40 50
pF1KE1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPP-----VPGGSM
:...: .: : : :.: :. ..: .:: : :
NP_002 MTPGKTSLVSLLLLLSLEA--IVKAGITIPRNP-GCPNSEDKNFPRTVM
10 20 30 40
60 70 80 90 100 110
pF1KE1 -KLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKE
.:.: : : . : . .::::::: . ::.:::: . .:.::.::::::.:.
NP_002 VNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNV
50 60 70 80 90 100
120 130 140 150 160
pF1KE1 DISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
: ::::::::: ::.::. : ::.:::.::.::::::::..:::
NP_002 DYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
110 120 130 140 150
>>NP_612141 (OMIM: 607587) interleukin-17D precursor [Ho (202 aa)
initn: 237 init1: 127 opt: 216 Z-score: 276.5 bits: 57.8 E(85289): 1.2e-08
Smith-Waterman score: 216; 39.0% identity (62.2% similar) in 82 aa overlap (77-155:89-170)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
::.::: : ...:: ::: . .: : :
NP_612 QLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 CINAQ-GKEDISMNSVPIQQETLVVRRKHQ--GCSVSFQLEKVLVTVGCTCVTPVIHHVQ
:... :.::. . :.:. . :.:.:: : . : . ::::::
NP_612 CLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDAD
120 130 140 150 160 170
NP_612 SINSSIDKQGAKLLLGPNDAPAGP
180 190 200
>>XP_005266478 (OMIM: 607587) PREDICTED: interleukin-17D (209 aa)
initn: 237 init1: 127 opt: 216 Z-score: 276.3 bits: 57.8 E(85289): 1.2e-08
Smith-Waterman score: 216; 39.0% identity (62.2% similar) in 82 aa overlap (77-155:96-177)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
::.::: : ...:: ::: . .: : :
XP_005 QLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 CINAQ-GKEDISMNSVPIQQETLVVRRKHQ--GCSVSFQLEKVLVTVGCTCVTPVIHHVQ
:... :.::. . :.:. . :.:.:: : . : . ::::::
XP_005 CLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDAD
130 140 150 160 170 180
XP_005 SINSSIDKQGAKLLLGPNDAPAGP
190 200
>>XP_016864836 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 225 init1: 138 opt: 199 Z-score: 258.4 bits: 53.7 E(85289): 1.2e-07
Smith-Waterman score: 199; 38.4% identity (61.6% similar) in 86 aa overlap (77-155:44-127)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
:: :::.:... ::.: : .. .:.: ::
XP_016 IEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLG
20 30 40 50 60 70
110 120 130 140 150
pF1KE1 CINA-QGKEDISMNSVPIQQETLVVRR------KHQGCSVSFQLEKVLVTVGCTCVTPVI
:.: .:: :: :::. ... : :: . : .: ..:::::.
XP_016 CVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMET--IAVGCTCIF
80 90 100 110 120
160
pF1KE1 HHVQ
>>XP_011535924 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 225 init1: 138 opt: 199 Z-score: 258.4 bits: 53.7 E(85289): 1.2e-07
Smith-Waterman score: 199; 38.4% identity (61.6% similar) in 86 aa overlap (77-155:44-127)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
:: :::.:... ::.: : .. .:.: ::
XP_011 IEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLG
20 30 40 50 60 70
110 120 130 140 150
pF1KE1 CINA-QGKEDISMNSVPIQQETLVVRR------KHQGCSVSFQLEKVLVTVGCTCVTPVI
:.: .:: :: :::. ... : :: . : .: ..:::::.
XP_011 CVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMET--IAVGCTCIF
80 90 100 110 120
160
pF1KE1 HHVQ
>>NP_001304916 (OMIM: 604627) interleukin-17B isoform 2 (128 aa)
initn: 225 init1: 138 opt: 199 Z-score: 258.4 bits: 53.7 E(85289): 1.2e-07
Smith-Waterman score: 199; 38.4% identity (61.6% similar) in 86 aa overlap (77-155:44-127)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
:: :::.:... ::.: : .. .:.: ::
NP_001 IEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLG
20 30 40 50 60 70
110 120 130 140 150
pF1KE1 CINA-QGKEDISMNSVPIQQETLVVRR------KHQGCSVSFQLEKVLVTVGCTCVTPVI
:.: .:: :: :::. ... : :: . : .: ..:::::.
NP_001 CVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMET--IAVGCTCIF
80 90 100 110 120
160
pF1KE1 HHVQ
>>XP_016864837 (OMIM: 604627) PREDICTED: interleukin-17B (128 aa)
initn: 225 init1: 138 opt: 199 Z-score: 258.4 bits: 53.7 E(85289): 1.2e-07
Smith-Waterman score: 199; 38.4% identity (61.6% similar) in 86 aa overlap (77-155:44-127)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
:: :::.:... ::.: : .. .:.: ::
XP_016 IEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLG
20 30 40 50 60 70
110 120 130 140 150
pF1KE1 CINA-QGKEDISMNSVPIQQETLVVRR------KHQGCSVSFQLEKVLVTVGCTCVTPVI
:.: .:: :: :::. ... : :: . : .: ..:::::.
XP_016 CVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMET--IAVGCTCIF
80 90 100 110 120
160
pF1KE1 HHVQ
>>NP_055258 (OMIM: 604627) interleukin-17B isoform 1 pre (180 aa)
initn: 213 init1: 138 opt: 199 Z-score: 256.1 bits: 53.8 E(85289): 1.6e-07
Smith-Waterman score: 199; 38.4% identity (61.6% similar) in 86 aa overlap (77-155:96-179)
50 60 70 80 90 100
pF1KE1 CPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG
:: :::.:... ::.: : .. .:.: ::
NP_055 IEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLG
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 CINA-QGKEDISMNSVPIQQETLVVRR------KHQGCSVSFQLEKVLVTVGCTCVTPVI
:.: .:: :: :::. ... : :: . : .: ..:::::.
NP_055 CVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMET--IAVGCTCIF
130 140 150 160 170 180
160
pF1KE1 HHVQ
163 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:47:59 2016 done: Sun Nov 6 16:48:00 2016
Total Scan time: 4.870 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]