Result of FASTA (omim) for
pFN21AE1646
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1646, 161 aa
1>>>pF1KE1646 161 - 161 aa - 161 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4149+/-0.00048; mu= 10.6320+/- 0.029
mean_var=54.6114+/-11.417, 0's: 0 Z-trim(108.3): 47 B-trim: 192 in 1/47
Lambda= 0.173553
statistics sampled from 16365 (16396) to 16365 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.56), E-opt: 0.2 (0.192), width: 16
Scan time: 4.860
The best scores are: opt bits E(85289)
NP_001620 (OMIM: 601367,603700) arachidonate 5-lip ( 161) 1046 270.2 1e-72
NP_001191335 (OMIM: 601367,603700) arachidonate 5- ( 218) 1046 270.3 1.3e-72
XP_016876011 (OMIM: 601367,603700) PREDICTED: arac ( 121) 698 183.1 1.3e-46
XP_016863702 (OMIM: 601733) PREDICTED: microsomal ( 147) 276 77.4 1e-14
NP_002404 (OMIM: 601733) microsomal glutathione S- ( 147) 276 77.4 1e-14
XP_016863701 (OMIM: 601733) PREDICTED: microsomal ( 147) 276 77.4 1e-14
XP_016863700 (OMIM: 601733) PREDICTED: microsomal ( 147) 276 77.4 1e-14
NP_001191295 (OMIM: 601733) microsomal glutathione ( 147) 276 77.4 1e-14
NP_665874 (OMIM: 246530,614037) leukotriene C4 syn ( 150) 255 72.2 3.9e-13
>>NP_001620 (OMIM: 601367,603700) arachidonate 5-lipoxyg (161 aa)
initn: 1046 init1: 1046 opt: 1046 Z-score: 1426.7 bits: 270.2 E(85289): 1e-72
Smith-Waterman score: 1046; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
70 80 90 100 110 120
130 140 150 160
pF1KE1 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
:::::::::::::::::::::::::::::::::::::::::
NP_001 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
130 140 150 160
>>NP_001191335 (OMIM: 601367,603700) arachidonate 5-lipo (218 aa)
initn: 1046 init1: 1046 opt: 1046 Z-score: 1424.5 bits: 270.3 E(85289): 1.3e-72
Smith-Waterman score: 1046; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:58-218)
10 20 30
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKV
::::::::::::::::::::::::::::::
NP_001 LGHIGNISHQCWAGCAAGGRAVLSGEPEANMDQETVGNVVLLAIVTLISVVQNGFFAHKV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 EHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMY
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 LFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTI
150 160 170 180 190 200
160
pF1KE1 STTISPLLLIP
:::::::::::
NP_001 STTISPLLLIP
210
>>XP_016876011 (OMIM: 601367,603700) PREDICTED: arachido (121 aa)
initn: 698 init1: 698 opt: 698 Z-score: 957.9 bits: 183.1 E(85289): 1.3e-46
Smith-Waterman score: 698; 98.1% identity (99.1% similar) in 107 aa overlap (55-161:15-121)
30 40 50 60 70 80
pF1KE1 FFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAA
. ::::::::::::::::::::::::::::
XP_016 MRLQEEKNMHLILLSENQNCVDAYPTFLAVLWSAGLLCSQVPAA
10 20 30 40
90 100 110 120 130 140
pF1KE1 FAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFE
50 60 70 80 90 100
150 160
pF1KE1 NYIKTISTTISPLLLIP
:::::::::::::::::
XP_016 NYIKTISTTISPLLLIP
110 120
>>XP_016863702 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 288 init1: 276 opt: 276 Z-score: 385.4 bits: 77.4 E(85289): 1e-14
Smith-Waterman score: 276; 37.2% identity (62.8% similar) in 129 aa overlap (7-135:3-131)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
:: .::: :...:. :...:: .: . . ::. ::::. :.:::
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
:. :: :. .:: :: .:: :. ::.:.. :. :: :: . :. .. :.
XP_016 VEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILA
60 70 80 90 100 110
130 140 150 160
pF1KE1 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
.: :... :: : .:
XP_016 LLTLLGALGIANSFLDEYLDLNIAKKLRRQF
120 130 140
>>NP_002404 (OMIM: 601733) microsomal glutathione S-tran (147 aa)
initn: 288 init1: 276 opt: 276 Z-score: 385.4 bits: 77.4 E(85289): 1e-14
Smith-Waterman score: 276; 37.2% identity (62.8% similar) in 129 aa overlap (7-135:3-131)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
:: .::: :...:. :...:: .: . . ::. ::::. :.:::
NP_002 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
:. :: :. .:: :: .:: :. ::.:.. :. :: :: . :. .. :.
NP_002 VEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILA
60 70 80 90 100 110
130 140 150 160
pF1KE1 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
.: :... :: : .:
NP_002 LLTLLGALGIANSFLDEYLDLNIAKKLRRQF
120 130 140
>>XP_016863701 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 288 init1: 276 opt: 276 Z-score: 385.4 bits: 77.4 E(85289): 1e-14
Smith-Waterman score: 276; 37.2% identity (62.8% similar) in 129 aa overlap (7-135:3-131)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
:: .::: :...:. :...:: .: . . ::. ::::. :.:::
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
:. :: :. .:: :: .:: :. ::.:.. :. :: :: . :. .. :.
XP_016 VEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILA
60 70 80 90 100 110
130 140 150 160
pF1KE1 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
.: :... :: : .:
XP_016 LLTLLGALGIANSFLDEYLDLNIAKKLRRQF
120 130 140
>>XP_016863700 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 288 init1: 276 opt: 276 Z-score: 385.4 bits: 77.4 E(85289): 1e-14
Smith-Waterman score: 276; 37.2% identity (62.8% similar) in 129 aa overlap (7-135:3-131)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
:: .::: :...:. :...:: .: . . ::. ::::. :.:::
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
:. :: :. .:: :: .:: :. ::.:.. :. :: :: . :. .. :.
XP_016 VEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILA
60 70 80 90 100 110
130 140 150 160
pF1KE1 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
.: :... :: : .:
XP_016 LLTLLGALGIANSFLDEYLDLNIAKKLRRQF
120 130 140
>>NP_001191295 (OMIM: 601733) microsomal glutathione S-t (147 aa)
initn: 288 init1: 276 opt: 276 Z-score: 385.4 bits: 77.4 E(85289): 1e-14
Smith-Waterman score: 276; 37.2% identity (62.8% similar) in 129 aa overlap (7-135:3-131)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
:: .::: :...:. :...:: .: . . ::. ::::. :.:::
NP_001 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNC
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
:. :: :. .:: :: .:: :. ::.:.. :. :: :: . :. .. :.
NP_001 VEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILA
60 70 80 90 100 110
130 140 150 160
pF1KE1 FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
.: :... :: : .:
NP_001 LLTLLGALGIANSFLDEYLDLNIAKKLRRQF
120 130 140
>>NP_665874 (OMIM: 246530,614037) leukotriene C4 synthas (150 aa)
initn: 240 init1: 240 opt: 255 Z-score: 356.8 bits: 72.2 E(85289): 3.9e-13
Smith-Waterman score: 255; 36.7% identity (64.1% similar) in 128 aa overlap (9-135:5-131)
10 20 30 40 50 60
pF1KE1 MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
:.::: :::..:. ...:. .: :. :: ::::: :. ::
NP_665 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNC
10 20 30 40 50
70 80 90 100 110
pF1KE1 VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYL-GERTQSTPGYIFGKRII
. .: :::.:: ::.. . ::. ::.:::.: .:: :: . . . .: : . : .
NP_665 SEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYA-SARAL
60 70 80 90 100 110
120 130 140 150 160
pF1KE1 LFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
.: ... :.. ..:
NP_665 WLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
120 130 140 150
161 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:38:35 2016 done: Sun Nov 6 14:38:36 2016
Total Scan time: 4.860 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]