Result of FASTA (omim) for
pFN21AE1637
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1637, 152 aa
1>>>pF1KE1637 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8111+/-0.000335; mu= 13.9498+/- 0.021
mean_var=54.6513+/-11.007, 0's: 0 Z-trim(115.4): 15 B-trim: 790 in 2/53
Lambda= 0.173490
statistics sampled from 25829 (25844) to 25829 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.303), width: 16
Scan time: 4.510
The best scores are: opt bits E(85289)
NP_004869 (OMIM: 605172) prostaglandin E synthase ( 152) 1031 265.6 2.3e-71
XP_011517512 (OMIM: 605172) PREDICTED: prostagland ( 180) 1031 265.6 2.6e-71
NP_064696 (OMIM: 138330) microsomal glutathione S- ( 155) 342 93.1 1.9e-19
NP_665735 (OMIM: 138330) microsomal glutathione S- ( 155) 342 93.1 1.9e-19
NP_665707 (OMIM: 138330) microsomal glutathione S- ( 155) 342 93.1 1.9e-19
NP_665734 (OMIM: 138330) microsomal glutathione S- ( 155) 342 93.1 1.9e-19
NP_001247440 (OMIM: 138330) microsomal glutathione ( 155) 342 93.1 1.9e-19
XP_006719142 (OMIM: 138330) PREDICTED: microsomal ( 124) 135 41.3 0.00061
XP_011518976 (OMIM: 138330) PREDICTED: microsomal ( 134) 135 41.3 0.00066
XP_011518975 (OMIM: 138330) PREDICTED: microsomal ( 148) 135 41.3 0.00071
NP_001247441 (OMIM: 138330) microsomal glutathione ( 106) 133 40.7 0.00076
NP_001254527 (OMIM: 138330) microsomal glutathione ( 87) 129 39.7 0.0013
>>NP_004869 (OMIM: 605172) prostaglandin E synthase [Hom (152 aa)
initn: 1031 init1: 1031 opt: 1031 Z-score: 1402.4 bits: 265.6 E(85289): 2.3e-71
Smith-Waterman score: 1031; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
70 80 90 100 110 120
130 140 150
pF1KE1 LRAPIRSVTYTLAQLPCASMALQILWEAARHL
::::::::::::::::::::::::::::::::
NP_004 LRAPIRSVTYTLAQLPCASMALQILWEAARHL
130 140 150
>>XP_011517512 (OMIM: 605172) PREDICTED: prostaglandin E (180 aa)
initn: 1031 init1: 1031 opt: 1031 Z-score: 1401.3 bits: 265.6 E(85289): 2.6e-71
Smith-Waterman score: 1031; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:29-180)
10 20 30
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAI
::::::::::::::::::::::::::::::::
XP_011 MSSGRGAWGRGCSSVELITPTVELRWPEMPAHSLVMSSPALPAFLLCSTLLVIKMYVVAI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 ITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 GPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
130 140 150 160 170 180
>>NP_064696 (OMIM: 138330) microsomal glutathione S-tran (155 aa)
initn: 325 init1: 234 opt: 342 Z-score: 470.2 bits: 93.1 E(85289): 1.9e-19
Smith-Waterman score: 342; 39.9% identity (68.5% similar) in 143 aa overlap (7-145:7-149)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
NP_064 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::: ::.:.: ::: .:..::. ::.: .: .:: .:. .:. ::.:
NP_064 KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA
70 80 90 100 110 120
120 130 140 150
pF1KE1 YLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
:: : : :.... .. ::: ..:
NP_064 YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
130 140 150
>>NP_665735 (OMIM: 138330) microsomal glutathione S-tran (155 aa)
initn: 325 init1: 234 opt: 342 Z-score: 470.2 bits: 93.1 E(85289): 1.9e-19
Smith-Waterman score: 342; 39.9% identity (68.5% similar) in 143 aa overlap (7-145:7-149)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
NP_665 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::: ::.:.: ::: .:..::. ::.: .: .:: .:. .:. ::.:
NP_665 KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA
70 80 90 100 110 120
120 130 140 150
pF1KE1 YLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
:: : : :.... .. ::: ..:
NP_665 YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
130 140 150
>>NP_665707 (OMIM: 138330) microsomal glutathione S-tran (155 aa)
initn: 325 init1: 234 opt: 342 Z-score: 470.2 bits: 93.1 E(85289): 1.9e-19
Smith-Waterman score: 342; 39.9% identity (68.5% similar) in 143 aa overlap (7-145:7-149)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
NP_665 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::: ::.:.: ::: .:..::. ::.: .: .:: .:. .:. ::.:
NP_665 KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA
70 80 90 100 110 120
120 130 140 150
pF1KE1 YLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
:: : : :.... .. ::: ..:
NP_665 YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
130 140 150
>>NP_665734 (OMIM: 138330) microsomal glutathione S-tran (155 aa)
initn: 325 init1: 234 opt: 342 Z-score: 470.2 bits: 93.1 E(85289): 1.9e-19
Smith-Waterman score: 342; 39.9% identity (68.5% similar) in 143 aa overlap (7-145:7-149)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
NP_665 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::: ::.:.: ::: .:..::. ::.: .: .:: .:. .:. ::.:
NP_665 KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA
70 80 90 100 110 120
120 130 140 150
pF1KE1 YLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
:: : : :.... .. ::: ..:
NP_665 YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
130 140 150
>>NP_001247440 (OMIM: 138330) microsomal glutathione S-t (155 aa)
initn: 325 init1: 234 opt: 342 Z-score: 470.2 bits: 93.1 E(85289): 1.9e-19
Smith-Waterman score: 342; 39.9% identity (68.5% similar) in 143 aa overlap (7-145:7-149)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
NP_001 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::: ::.:.: ::: .:..::. ::.: .: .:: .:. .:. ::.:
NP_001 KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA
70 80 90 100 110 120
120 130 140 150
pF1KE1 YLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
:: : : :.... .. ::: ..:
NP_001 YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
130 140 150
>>XP_006719142 (OMIM: 138330) PREDICTED: microsomal glut (124 aa)
initn: 129 init1: 105 opt: 135 Z-score: 191.7 bits: 41.3 E(85289): 0.00061
Smith-Waterman score: 135; 37.1% identity (65.7% similar) in 70 aa overlap (7-72:7-76)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
XP_006 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::.
XP_006 KYLRTDDRVERVRRAQEILGPERQIQKNLHVNETGVEMRMAGNAWKQTCNCLMAWSSKSQ
70 80 90 100 110 120
>>XP_011518976 (OMIM: 138330) PREDICTED: microsomal glut (134 aa)
initn: 118 init1: 105 opt: 135 Z-score: 191.2 bits: 41.3 E(85289): 0.00066
Smith-Waterman score: 135; 37.1% identity (65.7% similar) in 70 aa overlap (7-72:7-76)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
XP_011 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::.
XP_011 KYLRTDDRVERVRRAQEILGPERQIQKNLHVNETGVEMRMAGNAWKQTCNCLMAWSSKSQ
70 80 90 100 110 120
>>XP_011518975 (OMIM: 138330) PREDICTED: microsomal glut (148 aa)
initn: 118 init1: 105 opt: 135 Z-score: 190.5 bits: 41.3 E(85289): 0.00071
Smith-Waterman score: 135; 37.1% identity (65.7% similar) in 70 aa overlap (7-72:7-76)
10 20 30 40 50
pF1KE1 MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHG----GP
::.. .. :: .:... ::.... :. :: .:.:::::: . : .
XP_011 MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVA
.: :.: ::: ::.
XP_011 KYLRTDDRVERVRRAQEILGPERQIQKNLHVNETGVEMRMAGNAWKQTCNCLMAWSSKSQ
70 80 90 100 110 120
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:40:39 2016 done: Sun Nov 6 15:40:39 2016
Total Scan time: 4.510 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]