Result of FASTA (omim) for
pFN21AE1629
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1629, 146 aa
1>>>pF1KE1629 146 - 146 aa - 146 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2783+/-0.000412; mu= 12.9316+/- 0.026
mean_var=126.9074+/-24.289, 0's: 0 Z-trim(116.9): 225 B-trim: 809 in 2/53
Lambda= 0.113849
statistics sampled from 28056 (28417) to 28056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.333), width: 16
Scan time: 4.430
The best scores are: opt bits E(85289)
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146) 931 163.3 1.3e-40
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 494 91.5 5.3e-19
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 494 91.5 5.3e-19
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 494 91.5 5.3e-19
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 494 91.5 5.3e-19
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 487 90.4 1.2e-18
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 487 90.5 1.4e-18
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 465 86.7 1.4e-17
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 371 71.1 5.4e-13
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 371 71.1 5.4e-13
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 371 71.1 5.4e-13
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 371 71.1 5.4e-13
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 371 71.1 5.4e-13
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 371 71.1 5.4e-13
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 371 71.1 5.4e-13
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 373 71.7 5.5e-13
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 352 68.3 6e-12
XP_016873514 (OMIM: 608965,610427) PREDICTED: calc ( 170) 338 66.0 3e-11
NP_001287824 (OMIM: 608965,610427) calcium-binding ( 170) 338 66.0 3e-11
XP_011543485 (OMIM: 608965,610427) PREDICTED: calc ( 170) 338 66.0 3e-11
NP_001287825 (OMIM: 608965,610427) calcium-binding ( 170) 338 66.0 3e-11
NP_660201 (OMIM: 608965,610427) calcium-binding pr ( 275) 338 66.2 3.9e-11
XP_011543483 (OMIM: 608965,610427) PREDICTED: calc ( 295) 338 66.3 4.1e-11
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 328 64.3 8.9e-11
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 322 63.2 1.7e-10
NP_004267 (OMIM: 605563) calcium-binding protein 1 ( 167) 321 63.2 2e-10
NP_112482 (OMIM: 605563) calcium-binding protein 1 ( 227) 321 63.3 2.4e-10
NP_001028849 (OMIM: 605563) calcium-binding protei ( 370) 321 63.6 3.3e-10
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 314 62.2 5.3e-10
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226) 314 62.2 5.4e-10
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 309 61.2 7.8e-10
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 305 60.5 1.3e-09
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 292 58.4 5.8e-09
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 292 58.5 6.2e-09
XP_016875728 (OMIM: 605563) PREDICTED: calcium-bin ( 202) 290 58.2 7.7e-09
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 288 57.7 8.6e-09
XP_016875727 (OMIM: 605563) PREDICTED: calcium-bin ( 262) 290 58.3 9.1e-09
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 286 57.4 1.1e-08
XP_016875724 (OMIM: 605563) PREDICTED: calcium-bin ( 405) 290 58.6 1.2e-08
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 286 57.7 1.5e-08
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191) 277 56.0 3.3e-08
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 264 53.8 1.4e-07
NP_524144 (OMIM: 160780) myosin light chain 1/3, s ( 194) 260 53.2 2.3e-07
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 257 52.7 3e-07
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 257 52.7 3e-07
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 257 52.7 3e-07
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 252 51.8 4.9e-07
NP_524146 (OMIM: 160780) myosin light chain 1/3, s ( 150) 251 51.6 5.5e-07
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 245 50.6 1.1e-06
XP_011543484 (OMIM: 608965,610427) PREDICTED: calc ( 247) 247 51.2 1.2e-06
>>NP_059118 (OMIM: 605183) calmodulin-like protein 5 [Ho (146 aa)
initn: 931 init1: 931 opt: 931 Z-score: 850.2 bits: 163.3 E(85289): 1.3e-40
Smith-Waterman score: 931; 100.0% identity (100.0% similar) in 146 aa overlap (1-146:1-146)
10 20 30 40 50 60
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 DGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELD
70 80 90 100 110 120
130 140
pF1KE1 AMIREADVDQDGRVNYEEFARMLAQE
::::::::::::::::::::::::::
NP_059 AMIREADVDQDGRVNYEEFARMLAQE
130 140
>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo (149 aa)
initn: 489 init1: 253 opt: 494 Z-score: 462.2 bits: 91.5 E(85289): 5.3e-19
Smith-Waterman score: 494; 51.4% identity (83.6% similar) in 146 aa overlap (1-143:1-146)
10 20 30 40 50 60
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
:: .:: :. :..:.::: : ::.:::...:::..... :.: .::.:. .:.:::.::
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DGEISFQEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE
.: :.: :::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .:
NP_001 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
120 130 140
pF1KE1 ELDAMIREADVDQDGRVNYEEFARMLAQE
:.: ::::::.: ::.::::::..:.
NP_001 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [ (149 aa)
initn: 489 init1: 253 opt: 494 Z-score: 462.2 bits: 91.5 E(85289): 5.3e-19
Smith-Waterman score: 494; 51.4% identity (83.6% similar) in 146 aa overlap (1-143:1-146)
10 20 30 40 50 60
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
:: .:: :. :..:.::: : ::.:::...:::..... :.: .::.:. .:.:::.::
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DGEISFQEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE
.: :.: :::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .:
NP_001 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
120 130 140
pF1KE1 ELDAMIREADVDQDGRVNYEEFARMLAQE
:.: ::::::.: ::.::::::..:.
NP_001 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom (149 aa)
initn: 489 init1: 253 opt: 494 Z-score: 462.2 bits: 91.5 E(85289): 5.3e-19
Smith-Waterman score: 494; 51.4% identity (83.6% similar) in 146 aa overlap (1-143:1-146)
10 20 30 40 50 60
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
:: .:: :. :..:.::: : ::.:::...:::..... :.: .::.:. .:.:::.::
NP_008 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DGEISFQEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE
.: :.: :::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .:
NP_008 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
120 130 140
pF1KE1 ELDAMIREADVDQDGRVNYEEFARMLAQE
:.: ::::::.: ::.::::::..:.
NP_008 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa (149 aa)
initn: 489 init1: 253 opt: 494 Z-score: 462.2 bits: 91.5 E(85289): 5.3e-19
Smith-Waterman score: 494; 51.4% identity (83.6% similar) in 146 aa overlap (1-143:1-146)
10 20 30 40 50 60
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
:: .:: :. :..:.::: : ::.:::...:::..... :.: .::.:. .:.:::.::
NP_005 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DGEISFQEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE
.: :.: :::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .:
NP_005 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
120 130 140
pF1KE1 ELDAMIREADVDQDGRVNYEEFARMLAQE
:.: ::::::.: ::.::::::..:.
NP_005 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c (150 aa)
initn: 482 init1: 250 opt: 487 Z-score: 455.9 bits: 90.4 E(85289): 1.2e-18
Smith-Waterman score: 487; 51.0% identity (83.4% similar) in 145 aa overlap (2-143:3-147)
10 20 30 40 50
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSD
: .:: :. :..:.::: : ::.:::...:::..... :.: .::.:. .:.:::.:
XP_006 MQADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GDGEISFQEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQ
:.: :.: :::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .
XP_006 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD
70 80 90 100 110 120
120 130 140
pF1KE1 EELDAMIREADVDQDGRVNYEEFARMLAQE
::.: ::::::.: ::.::::::..:.
XP_006 EEVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140 150
>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform (197 aa)
initn: 517 init1: 250 opt: 487 Z-score: 454.6 bits: 90.5 E(85289): 1.4e-18
Smith-Waterman score: 487; 51.0% identity (83.4% similar) in 145 aa overlap (2-143:50-194)
10 20 30
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQ
: .:: :. :..:.::: : ::.:::...
NP_001 GCVVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTK
20 30 40 50 60 70
40 50 60 70 80
pF1KE1 ELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTA-AKKARA--GLEDLQVAFR
:::..... :.: .::.:. .:.:::.::.: :.: :::: :.: . . :... :::
NP_001 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFR
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 AFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQE
.::.::.:.:.. :::..:..::. : .::.: ::::::.: ::.::::::..:.
NP_001 VFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
140 150 160 170 180 190
>>NP_005176 (OMIM: 114184) calmodulin-like protein 3 [Ho (149 aa)
initn: 531 init1: 240 opt: 465 Z-score: 436.4 bits: 86.7 E(85289): 1.4e-17
Smith-Waterman score: 465; 47.0% identity (79.9% similar) in 149 aa overlap (1-146:1-149)
10 20 30 40 50 60
pF1KE1 MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG
:: .:: :. ...:.::: : ::.: :...:::..... :.: .::.:: ..::.: ::
NP_005 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DGEISFQEFL-TAAKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE
.: ..: ::: :.: . . :... :::.::.::.: ... :::..:. ::. : .:
NP_005 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
70 80 90 100 110 120
120 130 140
pF1KE1 ELDAMIREADVDQDGRVNYEEFARMLAQE
:.: ::: ::.: ::.::::::.:.:...
NP_005 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
130 140
>>NP_001316852 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa)
initn: 431 init1: 250 opt: 371 Z-score: 354.3 bits: 71.1 E(85289): 5.4e-13
Smith-Waterman score: 371; 50.9% identity (83.6% similar) in 110 aa overlap (37-143:1-110)
10 20 30 40 50 60
pF1KE1 PEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISF
... :.: .::.:. .:.:::.::.: :.:
NP_001 MRSLGQNPTEAELQDMINEVDADGNGTIDF
10 20 30
70 80 90 100 110 120
pF1KE1 QEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMI
:::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .::.: ::
NP_001 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI
40 50 60 70 80 90
130 140
pF1KE1 READVDQDGRVNYEEFARMLAQE
::::.: ::.::::::..:.
NP_001 READIDGDGQVNYEEFVQMMTAK
100 110
>>NP_001316853 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa)
initn: 431 init1: 250 opt: 371 Z-score: 354.3 bits: 71.1 E(85289): 5.4e-13
Smith-Waterman score: 371; 50.9% identity (83.6% similar) in 110 aa overlap (37-143:1-110)
10 20 30 40 50 60
pF1KE1 PEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISF
... :.: .::.:. .:.:::.::.: :.:
NP_001 MRSLGQNPTEAELQDMINEVDADGNGTIDF
10 20 30
70 80 90 100 110 120
pF1KE1 QEFLTA-AKKARA--GLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMI
:::: :.: . . :... :::.::.::.:.:.. :::..:..::. : .::.: ::
NP_001 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI
40 50 60 70 80 90
130 140
pF1KE1 READVDQDGRVNYEEFARMLAQE
::::.: ::.::::::..:.
NP_001 READIDGDGQVNYEEFVQMMTAK
100 110
146 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:35:52 2016 done: Sun Nov 6 15:35:52 2016
Total Scan time: 4.430 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]