Result of FASTA (omim) for
pFN21AE1626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1626, 142 aa
1>>>pF1KE1626 142 - 142 aa - 142 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1492+/-0.000357; mu= 11.9093+/- 0.022
mean_var=56.3837+/-11.644, 0's: 0 Z-trim(113.4): 36 B-trim: 0 in 0/53
Lambda= 0.170804
statistics sampled from 22725 (22758) to 22725 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.267), width: 16
Scan time: 4.710
The best scores are: opt bits E(85289)
NP_002280 (OMIM: 149750) alpha-lactalbumin precurs ( 142) 979 249.1 1.8e-66
XP_006719458 (OMIM: 149750) PREDICTED: alpha-lacta ( 149) 979 249.1 1.9e-66
NP_000230 (OMIM: 105200,153450) lysozyme C precurs ( 148) 337 90.9 7.9e-19
NP_898881 (OMIM: 612748) lysozyme-like protein 2 [ ( 194) 323 87.5 1.1e-17
NP_776246 (OMIM: 612749) sperm acrosome membrane-a ( 215) 321 87.0 1.7e-17
XP_016885001 (OMIM: 300593) PREDICTED: sperm acros ( 159) 294 80.3 1.3e-15
NP_995328 (OMIM: 300593) sperm acrosome-associated ( 159) 294 80.3 1.3e-15
NP_065159 (OMIM: 612751) lysozyme-like protein 6 p ( 148) 284 77.8 6.8e-15
NP_001186880 (OMIM: 612751) lysozyme-like protein ( 148) 284 77.8 6.8e-15
NP_001304154 (OMIM: 612749) sperm acrosome membran ( 123) 235 65.7 2.5e-11
NP_001304155 (OMIM: 612749) sperm acrosome membran ( 112) 231 64.7 4.5e-11
XP_016861195 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 227 63.8 1.1e-10
NP_653235 (OMIM: 612750) lysozyme-like protein 4 p ( 146) 227 63.8 1.1e-10
XP_016861194 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 227 63.8 1.1e-10
NP_001291315 (OMIM: 612750) lysozyme-like protein ( 146) 227 63.8 1.1e-10
XP_011517609 (OMIM: 612748) PREDICTED: lysozyme-li ( 163) 208 59.1 3.2e-09
XP_011517608 (OMIM: 612748) PREDICTED: lysozyme-li ( 181) 207 58.9 4.2e-09
XP_011531657 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 202 57.6 8.1e-09
>>NP_002280 (OMIM: 149750) alpha-lactalbumin precursor [ (142 aa)
initn: 979 init1: 979 opt: 979 Z-score: 1314.2 bits: 249.1 E(85289): 1.8e-66
Smith-Waterman score: 979; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLKDIDGYGGIALPELICTMFHTSGYDTQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRFFVPLFLVGILFPAILAKQFTKCELSQLLKDIDGYGGIALPELICTMFHTSGYDTQAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VENNESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILDIKGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VENNESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILDIKGI
70 80 90 100 110 120
130 140
pF1KE1 DYWLAHKALCTEKLEQWLCEKL
::::::::::::::::::::::
NP_002 DYWLAHKALCTEKLEQWLCEKL
130 140
>>XP_006719458 (OMIM: 149750) PREDICTED: alpha-lactalbum (149 aa)
initn: 979 init1: 979 opt: 979 Z-score: 1313.9 bits: 249.1 E(85289): 1.9e-66
Smith-Waterman score: 979; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:8-149)
10 20 30 40 50
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLKDIDGYGGIALPELICTMFHTS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFLGVAKMRFFVPLFLVGILFPAILAKQFTKCELSQLLKDIDGYGGIALPELICTMFHTS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GYDTQAIVENNESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GYDTQAIVENNESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKK
70 80 90 100 110 120
120 130 140
pF1KE1 ILDIKGIDYWLAHKALCTEKLEQWLCEKL
:::::::::::::::::::::::::::::
XP_006 ILDIKGIDYWLAHKALCTEKLEQWLCEKL
130 140
>>NP_000230 (OMIM: 105200,153450) lysozyme C precursor [ (148 aa)
initn: 288 init1: 189 opt: 337 Z-score: 459.0 bits: 90.9 E(85289): 7.9e-19
Smith-Waterman score: 337; 37.7% identity (69.6% similar) in 138 aa overlap (1-133:1-137)
10 20 30 40 50
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQ
:. .. : :: .: .. .: : .:::.. :: .::: ::.: . .: :::.:.
NP_000 MKALIVLGLV-LLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTR
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AIVEN--NESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKIL-
: : ..::.::.:::... ::.....: . : : .::. .:.:.:.: . :::...
NP_000 ATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVR
60 70 80 90 100 110
120 130 140
pF1KE1 DIKGIDYWLAHKALCTEKLEQWLCEKL
: .:: :.: . : ..
NP_000 DPQGIRAWVAWRNRCQNRDVRQYVQGCGV
120 130 140
>>NP_898881 (OMIM: 612748) lysozyme-like protein 2 [Homo (194 aa)
initn: 129 init1: 116 opt: 323 Z-score: 438.5 bits: 87.5 E(85289): 1.1e-17
Smith-Waterman score: 323; 35.5% identity (68.1% similar) in 141 aa overlap (7-140:53-192)
10 20 30
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DI
: :.: : . .: .:.:.:..... .
NP_898 TEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKIFSRAGL
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 DGYGGIALPELICTMFHTSGYDTQA-IVENNESTEYGLFQISNKLWCKSSQVPQSRNICD
:.: :..: . :: .. :::.: : : .. : .::.:::.. ::. ... .. : :
NP_898 DNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKLKEN-NHCH
90 100 110 120 130 140
100 110 120 130 140
pF1KE1 ISCDKFLDDDITDDIMCAKKIL-DIKGIDYWLAHKALCTEK-LEQWL--CEKL
..:. .. ::.:: :.:::::. . .:..:: . : : . : .: ::
NP_898 VACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
150 160 170 180 190
>>NP_776246 (OMIM: 612749) sperm acrosome membrane-assoc (215 aa)
initn: 189 init1: 149 opt: 321 Z-score: 435.1 bits: 87.0 E(85289): 1.7e-17
Smith-Waterman score: 321; 35.3% identity (66.9% similar) in 139 aa overlap (9-140:77-214)
10 20 30
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLKD--IDG
:.. :.:. :: . .:::...:.: .::
NP_776 STSAAGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDG
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE1 YGGIALPELICTMFHTSGYDTQAI-VENNESTEYGLFQISNKLWCKSSQVPQSRNICDIS
: : .: . .: . :::... :. : . ::. :.:::... :: :. .:. :.: .
NP_776 YRGYSLADWVCLAYFTSGFNAAALDYEADGSTNNGIFQINSRRWC-SNLTPNVPNVCRMY
110 120 130 140 150 160
100 110 120 130 140
pF1KE1 CDKFLDDDITDDIMCAKKIL-DIKGIDYWLAHKALCTEK-LEQWL--CEKL
:. .:. .. : ..:: :: . .:. :: : . : : : .:. :.
NP_776 CSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF
170 180 190 200 210
>>XP_016885001 (OMIM: 300593) PREDICTED: sperm acrosome- (159 aa)
initn: 260 init1: 160 opt: 294 Z-score: 401.2 bits: 80.3 E(85289): 1.3e-15
Smith-Waterman score: 294; 32.6% identity (66.0% similar) in 144 aa overlap (5-140:7-148)
10 20 30 40 50
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYD
: . :. .. .. :: . .:::. :. ..:: : .. . .: . ::.:
XP_016 MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 TQAIVENNE--STEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKI
: :.:..: :.:::.::... :: .. .: ..:.: ..: .:. : ::: :::.:
XP_016 T-AFVDHNPDGSSEYGIFQLNSAWWCDNGITP-TKNLCHMDCHDLLNRHILDDIRCAKQI
70 80 90 100 110
120 130 140
pF1KE1 LDIK-GIDYWLAHKALCT-EKLEQWL--CEKL
.. . :.. : . . :. . : .:: :.
XP_016 VSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP
120 130 140 150
>>NP_995328 (OMIM: 300593) sperm acrosome-associated pro (159 aa)
initn: 260 init1: 160 opt: 294 Z-score: 401.2 bits: 80.3 E(85289): 1.3e-15
Smith-Waterman score: 294; 32.6% identity (66.0% similar) in 144 aa overlap (5-140:7-148)
10 20 30 40 50
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYD
: . :. .. .. :: . .:::. :. ..:: : .. . .: . ::.:
NP_995 MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 TQAIVENNE--STEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKI
: :.:..: :.:::.::... :: .. .: ..:.: ..: .:. : ::: :::.:
NP_995 T-AFVDHNPDGSSEYGIFQLNSAWWCDNGITP-TKNLCHMDCHDLLNRHILDDIRCAKQI
70 80 90 100 110
120 130 140
pF1KE1 LDIK-GIDYWLAHKALCT-EKLEQWL--CEKL
.. . :.. : . . :. . : .:: :.
NP_995 VSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP
120 130 140 150
>>NP_065159 (OMIM: 612751) lysozyme-like protein 6 precu (148 aa)
initn: 108 init1: 75 opt: 284 Z-score: 388.4 bits: 77.8 E(85289): 6.8e-15
Smith-Waterman score: 284; 31.4% identity (66.4% similar) in 137 aa overlap (7-138:7-142)
10 20 30 40 50
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQ
..::. .. :. ...:.:.:.:. :.::. : .: . .: : : .. .
NP_065 MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNIS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 AIVENNE-STEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILD-
: :: . : .::::::... ::.. . :.:.: ..:. .:. .. : :::.:..
NP_065 KINENADGSFDYGLFQINSHYWCNDYK-SYSENLCHVDCQDLLNPNLLAGIHCAKRIVSG
70 80 90 100 110
120 130 140
pF1KE1 IKGIDYWLAHKALCTEK-LEQWLCEKL
.:.. :. . :. . : ::
NP_065 ARGMNNWVEWRLHCSGRPLFYWLTGCRLR
120 130 140
>>NP_001186880 (OMIM: 612751) lysozyme-like protein 6 pr (148 aa)
initn: 108 init1: 75 opt: 284 Z-score: 388.4 bits: 77.8 E(85289): 6.8e-15
Smith-Waterman score: 284; 31.4% identity (66.4% similar) in 137 aa overlap (7-138:7-142)
10 20 30 40 50
pF1KE1 MRFFVPLFLVGILFPAILAKQFTKCELSQLLK--DIDGYGGIALPELICTMFHTSGYDTQ
..::. .. :. ...:.:.:.:. :.::. : .: . .: : : .. .
NP_001 MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNIS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 AIVENNE-STEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILD-
: :: . : .::::::... ::.. . :.:.: ..:. .:. .. : :::.:..
NP_001 KINENADGSFDYGLFQINSHYWCNDYK-SYSENLCHVDCQDLLNPNLLAGIHCAKRIVSG
70 80 90 100 110
120 130 140
pF1KE1 IKGIDYWLAHKALCTEK-LEQWLCEKL
.:.. :. . :. . : ::
NP_001 ARGMNNWVEWRLHCSGRPLFYWLTGCRLR
120 130 140
>>NP_001304154 (OMIM: 612749) sperm acrosome membrane-as (123 aa)
initn: 143 init1: 84 opt: 235 Z-score: 324.4 bits: 65.7 E(85289): 2.5e-11
Smith-Waterman score: 235; 34.9% identity (64.2% similar) in 106 aa overlap (41-140:18-122)
20 30 40 50 60
pF1KE1 GILFPAILAKQFTKCELSQLLKDIDGYGGIALPEL-ICTMFHTSGYDTQAI-VENNESTE
::: .: . :::... :. : . ::.
NP_001 MTSGWTDTGDTAWLTAYALPYAGVCLAYFTSGFNAAALDYEADGSTN
10 20 30 40
70 80 90 100 110 120
pF1KE1 YGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKIL-DIKGIDYWLAHK
:.:::... :: :. .:. :.: . :. .:. .. : ..:: :: . .:. :: : .
NP_001 NGIFQINSRRWC-SNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWR
50 60 70 80 90 100
130 140
pF1KE1 ALCTEK-LEQWL--CEKL
: : : .:. :.
NP_001 HHCQGKDLTEWVDGCDF
110 120
142 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:52:32 2016 done: Sun Nov 6 14:52:33 2016
Total Scan time: 4.710 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]