Result of FASTA (omim) for
pFN21AE1619
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1619, 132 aa
1>>>pF1KE1619 132 - 132 aa - 132 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0786+/-0.000262; mu= 14.0941+/- 0.016
mean_var=83.5908+/-16.222, 0's: 0 Z-trim(122.1): 5 B-trim: 130 in 2/54
Lambda= 0.140280
statistics sampled from 39693 (39698) to 39693 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.465), width: 16
Scan time: 5.430
The best scores are: opt bits E(85289)
NP_001129 (OMIM: 601665,602311) agouti-related pro ( 132) 918 193.9 6.2e-50
XP_011527122 (OMIM: 600201,611742) PREDICTED: agou ( 132) 178 44.2 7.5e-05
NP_001663 (OMIM: 600201,611742) agouti-signaling p ( 132) 178 44.2 7.5e-05
XP_011527123 (OMIM: 600201,611742) PREDICTED: agou ( 132) 178 44.2 7.5e-05
XP_005260469 (OMIM: 600201,611742) PREDICTED: agou ( 136) 178 44.2 7.6e-05
>>NP_001129 (OMIM: 601665,602311) agouti-related protein (132 aa)
initn: 918 init1: 918 opt: 918 Z-score: 1017.5 bits: 193.9 E(85289): 6.2e-50
Smith-Waterman score: 918; 100.0% identity (100.0% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KE1 MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCR
70 80 90 100 110 120
130
pF1KE1 KLGTAMNPCSRT
::::::::::::
NP_001 KLGTAMNPCSRT
130
>>XP_011527122 (OMIM: 600201,611742) PREDICTED: agouti-s (132 aa)
initn: 184 init1: 164 opt: 178 Z-score: 208.1 bits: 44.2 E(85289): 7.5e-05
Smith-Waterman score: 178; 32.5% identity (54.5% similar) in 123 aa overlap (10-122:9-128)
10 20 30 40 50
pF1KE1 MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQAL-------LPELPGLGLRAPLKK
: ::.. :. : : : .: :..: : ..:.... : ::
XP_011 MDVTRLLLATLLVFLCFFTANSHLPPEEKLR-DDRSLRSNSSVNLLDVPSVSIVALNKK
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TTA---EQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYC
. . ::. .. .: . . .. : : :. :: ..:: ::::::.: :
XP_011 SKQIGRKAAEKKRSSKKEASMKKV-VRPRTPLSAP-CVATRNSCKPPAPACCDPCASCQC
60 70 80 90 100 110
120 130
pF1KE1 RFFNAFCYCRKLGTAMNPCSRT
::: . : :: :
XP_011 RFFRSACSCRVLSLNC
120 130
>>NP_001663 (OMIM: 600201,611742) agouti-signaling prote (132 aa)
initn: 184 init1: 164 opt: 178 Z-score: 208.1 bits: 44.2 E(85289): 7.5e-05
Smith-Waterman score: 178; 32.5% identity (54.5% similar) in 123 aa overlap (10-122:9-128)
10 20 30 40 50
pF1KE1 MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQAL-------LPELPGLGLRAPLKK
: ::.. :. : : : .: :..: : ..:.... : ::
NP_001 MDVTRLLLATLLVFLCFFTANSHLPPEEKLR-DDRSLRSNSSVNLLDVPSVSIVALNKK
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TTA---EQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYC
. . ::. .. .: . . .. : : :. :: ..:: ::::::.: :
NP_001 SKQIGRKAAEKKRSSKKEASMKKV-VRPRTPLSAP-CVATRNSCKPPAPACCDPCASCQC
60 70 80 90 100 110
120 130
pF1KE1 RFFNAFCYCRKLGTAMNPCSRT
::: . : :: :
NP_001 RFFRSACSCRVLSLNC
120 130
>>XP_011527123 (OMIM: 600201,611742) PREDICTED: agouti-s (132 aa)
initn: 184 init1: 164 opt: 178 Z-score: 208.1 bits: 44.2 E(85289): 7.5e-05
Smith-Waterman score: 178; 32.5% identity (54.5% similar) in 123 aa overlap (10-122:9-128)
10 20 30 40 50
pF1KE1 MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQAL-------LPELPGLGLRAPLKK
: ::.. :. : : : .: :..: : ..:.... : ::
XP_011 MDVTRLLLATLLVFLCFFTANSHLPPEEKLR-DDRSLRSNSSVNLLDVPSVSIVALNKK
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TTA---EQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYC
. . ::. .. .: . . .. : : :. :: ..:: ::::::.: :
XP_011 SKQIGRKAAEKKRSSKKEASMKKV-VRPRTPLSAP-CVATRNSCKPPAPACCDPCASCQC
60 70 80 90 100 110
120 130
pF1KE1 RFFNAFCYCRKLGTAMNPCSRT
::: . : :: :
XP_011 RFFRSACSCRVLSLNC
120 130
>>XP_005260469 (OMIM: 600201,611742) PREDICTED: agouti-s (136 aa)
initn: 184 init1: 164 opt: 178 Z-score: 207.9 bits: 44.2 E(85289): 7.6e-05
Smith-Waterman score: 178; 32.5% identity (54.5% similar) in 123 aa overlap (10-122:13-132)
10 20 30 40 50
pF1KE1 MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQAL-------LPELPGLGLRAP
: ::.. :. : : : .: :..: : ..:.... :
XP_005 MPPGMDVTRLLLATLLVFLCFFTANSHLPPEEKLR-DDRSLRSNSSVNLLDVPSVSIVAL
10 20 30 40 50
60 70 80 90 100
pF1KE1 LKKTTA---EQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCAT
::. . ::. .. .: . . .. : : :. :: ..:: ::::::.
XP_005 NKKSKQIGRKAAEKKRSSKKEASMKKV-VRPRTPLSAP-CVATRNSCKPPAPACCDPCAS
60 70 80 90 100 110
110 120 130
pF1KE1 CYCRFFNAFCYCRKLGTAMNPCSRT
: :::: . : :: :
XP_005 CQCRFFRSACSCRVLSLNC
120 130
132 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:50:37 2016 done: Sun Nov 6 09:50:38 2016
Total Scan time: 5.430 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]