Result of FASTA (omim) for
pFN21AE1591
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1591, 462 aa
1>>>pF1KE1591 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6386+/-0.000273; mu= 9.8483+/- 0.017
mean_var=171.1966+/-34.447, 0's: 0 Z-trim(123.6): 401 B-trim: 0 in 0/60
Lambda= 0.098023
statistics sampled from 43393 (43812) to 43393 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.514), width: 16
Scan time: 8.380
The best scores are: opt bits E(85289)
XP_005257611 (OMIM: 180240,612376) PREDICTED: reti ( 462) 3167 459.3 9.6e-129
NP_000955 (OMIM: 180240,612376) retinoic acid rece ( 462) 3167 459.3 9.6e-129
XP_005257610 (OMIM: 180240,612376) PREDICTED: reti ( 462) 3167 459.3 9.6e-129
NP_001138773 (OMIM: 180240,612376) retinoic acid r ( 462) 3167 459.3 9.6e-129
XP_011523397 (OMIM: 180240,612376) PREDICTED: reti ( 462) 3167 459.3 9.6e-129
NP_001019980 (OMIM: 180240,612376) retinoic acid r ( 457) 2754 400.9 3.6e-111
XP_005257609 (OMIM: 180240,612376) PREDICTED: reti ( 478) 2749 400.2 6.2e-111
XP_011523398 (OMIM: 180240,612376) PREDICTED: reti ( 404) 2735 398.2 2.1e-110
NP_001277145 (OMIM: 180220,615524) retinoic acid r ( 455) 2426 354.5 3.3e-97
XP_016880409 (OMIM: 180240,612376) PREDICTED: reti ( 343) 2308 337.8 2.9e-92
NP_001277229 (OMIM: 180220,615524) retinoic acid r ( 405) 2228 326.5 8.2e-89
NP_000956 (OMIM: 180220,615524) retinoic acid rece ( 448) 2227 326.4 9.8e-89
NP_001277195 (OMIM: 180220,615524) retinoic acid r ( 399) 2225 326.1 1.1e-88
NP_000957 (OMIM: 180190) retinoic acid receptor ga ( 454) 2167 317.9 3.5e-86
NP_001036193 (OMIM: 180190) retinoic acid receptor ( 443) 2134 313.2 8.8e-85
NP_001230659 (OMIM: 180190) retinoic acid receptor ( 382) 2068 303.9 5.1e-82
NP_001138774 (OMIM: 180240,612376) retinoic acid r ( 365) 2035 299.2 1.3e-80
NP_001230661 (OMIM: 180190) retinoic acid receptor ( 432) 1831 270.4 6.9e-72
NP_001277205 (OMIM: 180220,615524) retinoic acid r ( 336) 1828 269.9 7.6e-72
NP_001277146 (OMIM: 180220,615524) retinoic acid r ( 336) 1828 269.9 7.6e-72
NP_057236 (OMIM: 180220,615524) retinoic acid rece ( 336) 1828 269.9 7.6e-72
NP_001230660 (OMIM: 180190) retinoic acid receptor ( 333) 1731 256.2 1e-67
NP_001277206 (OMIM: 180220,615524) retinoic acid r ( 402) 1270 191.0 5e-48
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 724 113.9 1.1e-24
XP_005246679 (OMIM: 168600,601828) PREDICTED: nucl ( 535) 723 113.8 1.2e-24
NP_006177 (OMIM: 168600,601828) nuclear receptor s ( 598) 723 113.8 1.3e-24
XP_016859708 (OMIM: 168600,601828) PREDICTED: nucl ( 598) 723 113.8 1.3e-24
XP_005246678 (OMIM: 168600,601828) PREDICTED: nucl ( 609) 723 113.8 1.3e-24
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 713 112.3 2.7e-24
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 713 112.3 2.8e-24
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 712 112.1 2.9e-24
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 712 112.2 3.5e-24
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 701 110.5 7.7e-24
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 682 107.9 5.7e-23
NP_008912 (OMIM: 600542,612237) nuclear receptor s ( 626) 684 108.3 6.1e-23
XP_016870651 (OMIM: 600542,612237) PREDICTED: nucl ( 626) 684 108.3 6.1e-23
NP_775292 (OMIM: 600542,612237) nuclear receptor s ( 637) 684 108.3 6.2e-23
XP_006719426 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 674 106.9 1.6e-22
XP_006719427 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 674 106.9 1.6e-22
NP_002126 (OMIM: 139139) nuclear receptor subfamil ( 598) 674 106.9 1.6e-22
XP_005268881 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 674 106.9 1.6e-22
NP_775180 (OMIM: 139139) nuclear receptor subfamil ( 598) 674 106.9 1.6e-22
XP_016874736 (OMIM: 139139) PREDICTED: nuclear rec ( 602) 674 106.9 1.6e-22
NP_001189162 (OMIM: 139139) nuclear receptor subfa ( 611) 674 106.9 1.6e-22
NP_001189163 (OMIM: 139139) nuclear receptor subfa ( 652) 674 106.9 1.7e-22
XP_005268879 (OMIM: 139139) PREDICTED: nuclear rec ( 670) 674 106.9 1.7e-22
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 663 105.1 3.1e-22
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 663 105.2 3.5e-22
XP_016856131 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 645 102.7 2.1e-21
XP_016856135 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 645 102.7 2.1e-21
>>XP_005257611 (OMIM: 180240,612376) PREDICTED: retinoic (462 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 2432.3 bits: 459.3 E(85289): 9.6e-129
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
370 380 390 400 410 420
430 440 450 460
pF1KE1 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
::::::::::::::::::::::::::::::::::::::::::
XP_005 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
430 440 450 460
>>NP_000955 (OMIM: 180240,612376) retinoic acid receptor (462 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 2432.3 bits: 459.3 E(85289): 9.6e-129
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
370 380 390 400 410 420
430 440 450 460
pF1KE1 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
::::::::::::::::::::::::::::::::::::::::::
NP_000 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
430 440 450 460
>>XP_005257610 (OMIM: 180240,612376) PREDICTED: retinoic (462 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 2432.3 bits: 459.3 E(85289): 9.6e-129
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
370 380 390 400 410 420
430 440 450 460
pF1KE1 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
::::::::::::::::::::::::::::::::::::::::::
XP_005 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
430 440 450 460
>>NP_001138773 (OMIM: 180240,612376) retinoic acid recep (462 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 2432.3 bits: 459.3 E(85289): 9.6e-129
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
370 380 390 400 410 420
430 440 450 460
pF1KE1 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
::::::::::::::::::::::::::::::::::::::::::
NP_001 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
430 440 450 460
>>XP_011523397 (OMIM: 180240,612376) PREDICTED: retinoic (462 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 2432.3 bits: 459.3 E(85289): 9.6e-129
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
370 380 390 400 410 420
430 440 450 460
pF1KE1 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
::::::::::::::::::::::::::::::::::::::::::
XP_011 DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
430 440 450 460
>>NP_001019980 (OMIM: 180240,612376) retinoic acid recep (457 aa)
initn: 2738 init1: 2738 opt: 2754 Z-score: 2116.7 bits: 400.9 E(85289): 3.6e-111
Smith-Waterman score: 2754; 91.4% identity (93.6% similar) in 454 aa overlap (9-462:10-457)
10 20 30 40 50
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPA
:::. . . : ..: :: :: .: . :. . :. :
NP_001 MYESVEVGGPTPNPFLVVDFYNQNRACLLPE--KGLPAPGPYST-PLRTPLWNGSNHS--
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 MVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 LTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 VEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 AGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEAL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 KVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEG
360 370 380 390 400 410
420 430 440 450 460
pF1KE1 LDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 LDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
420 430 440 450
>>XP_005257609 (OMIM: 180240,612376) PREDICTED: retinoic (478 aa)
initn: 2736 init1: 2736 opt: 2749 Z-score: 2112.7 bits: 400.2 E(85289): 6.2e-111
Smith-Waterman score: 2749; 93.0% identity (94.8% similar) in 443 aa overlap (23-462:36-478)
10 20 30 40 50
pF1KE1 MASNSSSCPTPGGGHLNGYPVPPYAFFF-PPMLGGLSPPGALTTLQHQLPVS
::: : : : : .: . : .
XP_005 MTQAGVSFRHSVRAAQCHTRVPNTWPRATRPYASCRRSPRLRGRWPGSAGQGAGGRAPRA
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 GYSTP--SPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCK
:. . . ..:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GWRAGDVTGSAIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 GFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 PKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 ELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE1 LTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE1 MLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE1 IQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
430 440 450 460 470
>>XP_011523398 (OMIM: 180240,612376) PREDICTED: retinoic (404 aa)
initn: 2735 init1: 2735 opt: 2735 Z-score: 2102.9 bits: 398.2 E(85289): 2.1e-110
Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 402 aa overlap (61-462:3-404)
40 50 60 70 80 90
pF1KE1 MLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFV
::::::::::::::::::::::::::::::
XP_011 MPIETQSSSSEEIVPSPPSPPPLPRIYKPCFV
10 20 30
100 110 120 130 140 150
pF1KE1 CQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 VGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 NNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE1 LRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE1 AICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAK
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE1 GAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSP
340 350 360 370 380 390
460
pF1KE1 SSNRSSPATHSP
::::::::::::
XP_011 SSNRSSPATHSP
400
>>NP_001277145 (OMIM: 180220,615524) retinoic acid recep (455 aa)
initn: 2459 init1: 2282 opt: 2426 Z-score: 1866.1 bits: 354.5 E(85289): 3.3e-97
Smith-Waterman score: 2452; 78.0% identity (90.1% similar) in 464 aa overlap (1-462:1-452)
10 20 30 40 50
pF1KE1 MASNSSSCPTPG-GGHLNGYPVPPYAFFFPPMLGGLS-PPGALTTLQHQLPVSGYSTPSP
:.... .::.:. .::.. ::. :: ..:::..:::: :: : :. . : :: :::::
NP_001 MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPP--LHGLHGHPPPSGCSTPSP
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 ATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQK
:::::::.::::.::::::: : ::.::::::::::::::::::::::::::::::::::
NP_001 ATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESY
::.:::::::::.:::::::::::::::::::::::::::::::::::::. : ::.:::
NP_001 NMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 TLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIK
.: :. .: ::.:::::::::.::::::::::.:...:: ::. ::::::::.::::::
NP_001 EMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 TVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMH
:::::.::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 NAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEA
::::::::::::.::::::::::::.:::::::::::::::::::.: .:: ::::::::
NP_001 NAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 LKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE
::.:.::::::.::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 LKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE
360 370 380 390 400 410
420 430 440 450 460
pF1KE1 GLDTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
: . :. :...: . :::.:::: ..: ...::
NP_001 GHEPLT--PSSSGNTA--------EHSPSISPSSVENSGVSQSPLVQ
420 430 440 450
>>XP_016880409 (OMIM: 180240,612376) PREDICTED: retinoic (343 aa)
initn: 2308 init1: 2308 opt: 2308 Z-score: 1777.5 bits: 337.8 E(85289): 2.9e-92
Smith-Waterman score: 2308; 100.0% identity (100.0% similar) in 343 aa overlap (120-462:1-343)
90 100 110 120 130 140
pF1KE1 VCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCF
::::::::::::::::::::::::::::::
XP_016 MVYTCHRDKNCIINKVTRNRCQYCRLQKCF
10 20 30
150 160 170 180 190 200
pF1KE1 EVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYT
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 TNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDIL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE1 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE1 SAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISA
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE1 KGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQPGGGGRDGGGLAPPPGSCSPSLS
280 290 300 310 320 330
450 460
pF1KE1 PSSNRSSPATHSP
:::::::::::::
XP_016 PSSNRSSPATHSP
340
462 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:10:29 2016 done: Sun Nov 6 23:10:30 2016
Total Scan time: 8.380 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]