Result of FASTA (omim) for
pFN21AE1575
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1575, 365 aa
1>>>pF1KE1575 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0478+/-0.000362; mu= 19.0366+/- 0.022
mean_var=82.6570+/-17.081, 0's: 0 Z-trim(115.2): 136 B-trim: 1498 in 2/54
Lambda= 0.141070
statistics sampled from 25339 (25503) to 25339 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.299), width: 16
Scan time: 7.980
The best scores are: opt bits E(85289)
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 2276 472.9 5.1e-133
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 2273 472.3 7.8e-133
XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA ( 362) 2262 470.0 3.6e-132
XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA ( 391) 2257 469.0 7.8e-132
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 2095 436.0 6.2e-122
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 2014 419.6 5.7e-117
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 1997 416.1 6.3e-116
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 1904 397.2 3.3e-110
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 1904 397.2 3.5e-110
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 1904 397.2 3.6e-110
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 1904 397.2 3.6e-110
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 1895 395.3 1.1e-109
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 1870 390.2 3.7e-108
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 1866 389.4 6.3e-108
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 1866 389.4 6.4e-108
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 1842 384.5 1.9e-106
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 1840 384.2 2.9e-106
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 1830 382.1 1.1e-105
XP_011512859 (OMIM: 106300,142830,608579) PREDICTE ( 323) 1795 374.9 1.4e-103
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 1782 372.4 1e-102
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 1782 372.4 1e-102
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 1303 274.8 1.9e-73
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 1294 272.8 5.3e-73
NP_001091948 (OMIM: 143110) HLA class I histocompa ( 254) 1045 222.2 1e-57
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 816 175.7 1.4e-43
XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 795 171.3 2.1e-42
XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 795 171.3 2.1e-42
XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 737 159.6 9.5e-39
NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 737 159.6 9.5e-39
NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 730 158.2 2.5e-38
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 688 149.6 9.1e-36
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 675 147.0 5.4e-35
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 593 130.2 5.1e-30
NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 571 125.7 1.1e-28
NP_001181929 (OMIM: 600764) major histocompatibili ( 249) 543 120.0 5.8e-27
XP_006711349 (OMIM: 600764) PREDICTED: major histo ( 312) 533 118.1 2.8e-26
NP_001181964 (OMIM: 600764) major histocompatibili ( 214) 530 117.3 3.2e-26
NP_001170990 (OMIM: 600169) MHC class I polypeptid ( 332) 514 114.2 4.2e-25
NP_000238 (OMIM: 600169) MHC class I polypeptide-r ( 383) 498 111.0 4.5e-24
NP_005922 (OMIM: 602436) MHC class I polypeptide-r ( 383) 482 107.8 4.3e-23
NP_001276089 (OMIM: 602436) MHC class I polypeptid ( 351) 454 102.0 2.1e-21
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 452 101.6 2.5e-21
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 423 95.8 1.7e-19
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 423 95.8 1.7e-19
NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 380 86.7 4.2e-17
NP_001297142 (OMIM: 600764) major histocompatibili ( 178) 380 86.7 4.4e-17
NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 380 86.9 5.7e-17
NP_001276082 (OMIM: 600169) MHC class I polypeptid ( 235) 374 85.6 1.3e-16
NP_001276081 (OMIM: 600169) MHC class I polypeptid ( 235) 374 85.6 1.3e-16
NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 369 84.6 2.6e-16
>>NP_002107 (OMIM: 142800,608579) HLA class I histocompa (365 aa)
initn: 2276 init1: 2276 opt: 2276 Z-score: 2509.1 bits: 472.9 E(85289): 5.1e-133
Smith-Waterman score: 2276; 91.2% identity (96.2% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
:::::::::.::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_002 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
:::::::::::::::::::::::::..::::::.::::: .: :::::: ::::::
NP_002 DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
::::::: ::::::::.:::::::::::::::::::::::::::::.::::.::::::
NP_002 IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
::::.: :::::::::::::::::::: :::::::: .::::::::::::.:::::::::
NP_002 RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::::::::::.::::::.::::::::::::::::::::::
NP_002 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
:::::::::::::::::.::::.:::::::::::::::::::::.::::::::::::.::
NP_002 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL
310 320 330 340 350 360
pF1KE1 TACKV
:::::
NP_002 TACKV
>>NP_001229687 (OMIM: 142800,608579) HLA class I histoco (365 aa)
initn: 2273 init1: 2273 opt: 2273 Z-score: 2505.8 bits: 472.3 E(85289): 7.8e-133
Smith-Waterman score: 2273; 90.7% identity (96.4% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
:::::::::.::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
:::::::.:::::::::::::::::..:::.:::::::: .: :::::::::::::
NP_001 DSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
::::::::::::::::.:::::::::::::::::::::::::::::.::::..: :::
NP_001 IMYGCDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAVHAAEQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:.:::::::. :::::::::::::::: :::::::: .::::::::::::.:::::::::
NP_001 RVYLEGRCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::::::::::.::::::.::::::::::::::::::::::
NP_001 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
:::::::::::::::::.::::.:::::::::::::::::::::.::::::::::::.::
NP_001 SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL
310 320 330 340 350 360
pF1KE1 TACKV
:::::
NP_001 TACKV
>>XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA clas (362 aa)
initn: 2262 init1: 2262 opt: 2262 Z-score: 2493.8 bits: 470.0 E(85289): 3.6e-132
Smith-Waterman score: 2262; 92.0% identity (95.6% similar) in 362 aa overlap (4-365:1-362)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
:::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 MAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
::::::::::::::::::::::::: .::.::::::: : .: :::::: ::::.:
XP_016 DSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
:::::::: : ::::::.: ::::::::::.:::::::::::::: :..:::.:: :::
XP_016 RMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
XP_016 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
::::::::::::::::::::::.::::::::::::::::::::::::::::::::::.::
XP_016 SSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDVSL
300 310 320 330 340 350
pF1KE1 TACKV
:::::
XP_016 TACKV
360
>>XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA clas (391 aa)
initn: 2257 init1: 2257 opt: 2257 Z-score: 2487.8 bits: 469.0 E(85289): 7.8e-132
Smith-Waterman score: 2257; 92.0% identity (95.6% similar) in 361 aa overlap (4-364:1-361)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
:::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_005 MAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
::::::::::::::::::::::::: .::.::::::: : .: :::::: ::::.:
XP_005 DSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
:::::::: : ::::::.: ::::::::::.:::::::::::::: :..:::.:: :::
XP_005 RMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
XP_005 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
::::::::::::::::::::::.::::::::::::::::::::::::::::::::::.::
XP_005 SSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDVSL
300 310 320 330 340 350
pF1KE1 TACKV
::::
XP_005 TACKGESLEGLMCVGCWAEQWTQLCYGVSFHWMY
360 370 380 390
>>NP_005505 (OMIM: 106300,142830,608579) major histocomp (362 aa)
initn: 2095 init1: 2095 opt: 2095 Z-score: 2310.1 bits: 436.0 E(85289): 6.2e-122
Smith-Waterman score: 2095; 84.5% identity (93.4% similar) in 362 aa overlap (1-362:1-362)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
: ::::::..::::.:::::.::::::::::::::::::::::::::.::::::::::::
NP_005 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
:::::: : :::::::::::::::::::. ::..:::::::: :::::: ::::.:
NP_005 DSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
:::::::::::.:::..: ::::::::::::::::::::: ::::::::::.:.::::
NP_005 SMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
::::::.:::::::::::::. :.:.: ::::.::: .::::::::::::.:::::::::
NP_005 RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::: ::::::.::::::.:::::::::::::::::::::::
NP_005 WQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
::: :.:::::.:::.....:. :::::::: ::::: ::::::::: ::::::::.::
NP_005 SSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSL
310 320 330 340 350 360
pF1KE1 TACKV
::
NP_005 TA
>>NP_001229971 (OMIM: 142840,177900,609423) HLA class I (366 aa)
initn: 1926 init1: 1845 opt: 2014 Z-score: 2220.9 bits: 419.6 E(85289): 5.7e-117
Smith-Waterman score: 2014; 81.4% identity (91.0% similar) in 365 aa overlap (1-364:1-365)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
: :::::.:.:::::.::::.::: ::::::: :.::::::::::::.::::::::::::
NP_001 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
:::::: : ::::::.::::::::::.:.: : ..:.:: ::: :::::::::::.:
NP_001 DSDAASPRGEPRAPWVEQEGPEYWDRETQNYKRQAQADRVSLRNLRGYYNQSEDGSHTLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
::::::.:::::.::::.:.::::::::::::::::::::: :::::::: :.:. :::
NP_001 RMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:::::: ::::::::::::::::::.. ::::.::: .::::::::::::.:::::::::
NP_001 RAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::::::::::.::::::::::::::.::::: .:::: :::
NP_001 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEP
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 SSQPTIPIVGIIAGL-VLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMS
::::::::.::.::: :: .. ::::.:.: ::::: :::: :::: :.:::::: :
NP_001 SSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDES
310 320 330 340 350 360
360
pF1KE1 LTACKV
: .::
NP_001 LITCKA
>>NP_002108 (OMIM: 142840,177900,609423) HLA class I his (366 aa)
initn: 1909 init1: 1828 opt: 1997 Z-score: 2202.2 bits: 416.1 E(85289): 6.3e-116
Smith-Waterman score: 1997; 80.8% identity (90.7% similar) in 365 aa overlap (1-364:1-365)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
: :::::.:.:::::.::::.::: ::::::: :.::::::::::::.::::::::::::
NP_002 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
:::::: : ::::::.::::::::::.:.. : ..:.:: ::: :::::::::::.:
NP_002 DSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
:: :::.:::::.::::.:.::::::::::::::::::::: :::::::: :.:. :::
NP_002 RMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:::::: ::::::::::::::::::.. ::::.::: .::::::::::::.:::::::::
NP_002 RAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
:::::::::::::::::::::::::::::.::::::::::::::.::::: .:::: :::
NP_002 WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEP
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 SSQPTIPIVGIIAGL-VLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMS
::::::::.::.::: :: .. ::::.:.: ::::: :::: :::: :.:::::: :
NP_002 SSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDES
310 320 330 340 350 360
360
pF1KE1 LTACKV
: .::
NP_002 LITCKA
>>XP_016866302 (OMIM: 143110) PREDICTED: HLA class I his (388 aa)
initn: 1932 init1: 1904 opt: 1904 Z-score: 2099.6 bits: 397.2 E(85289): 3.3e-110
Smith-Waterman score: 1904; 76.9% identity (91.3% similar) in 355 aa overlap (4-358:1-355)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
::::.:.::::::::::.:::::::.::: :.::::::::::.::: :::::::.::
XP_016 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRF
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
::::: ::::: ::.:::::.::. .: .::..:::: .:: :: ::::: ::::.:
XP_016 DSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
: :::.:::::.::::.: ::::::::.:::::::::::: .:::::: .:. . ::..
XP_016 GMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:.::::.:.: ::::::::::::::.: ::.:..:: .::::::::::::.:::::::::
XP_016 RTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
::::::.::::::::::::::::::::::.:::: :.::::::::::::::.:: ::::
XP_016 WQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
: :::::::::.::::..:::..::::::::::.:::::. :::::::. . ..:. :
XP_016 SPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGNLMIT
300 310 320 330 340 350
pF1KE1 TACKV
XP_016 WWSSLFLLGVLFQGYLGCLRSHSVLGRRKES
360 370 380
>>XP_016866301 (OMIM: 143110) PREDICTED: HLA class I his (420 aa)
initn: 1932 init1: 1904 opt: 1904 Z-score: 2099.2 bits: 397.2 E(85289): 3.5e-110
Smith-Waterman score: 1904; 76.9% identity (91.3% similar) in 355 aa overlap (4-358:1-355)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
::::.:.::::::::::.:::::::.::: :.::::::::::.::: :::::::.::
XP_016 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRF
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
::::: ::::: ::.:::::.::. .: .::..:::: .:: :: ::::: ::::.:
XP_016 DSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
: :::.:::::.::::.: ::::::::.:::::::::::: .:::::: .:. . ::..
XP_016 GMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:.::::.:.: ::::::::::::::.: ::.:..:: .::::::::::::.:::::::::
XP_016 RTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
::::::.::::::::::::::::::::::.:::: :.::::::::::::::.:: ::::
XP_016 WQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
: :::::::::.::::..:::..::::::::::.:::::. :::::::. . ..:. :
XP_016 SPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGNLMIT
300 310 320 330 340 350
pF1KE1 TACKV
XP_016 WWSSLFLLGVLFQGYLGCLRSHSVLGRRKNGITCFRDEAKYLWNLLHTEFIILFPLMPLT
360 370 380 390 400 410
>>XP_016866299 (OMIM: 143110) PREDICTED: HLA class I his (435 aa)
initn: 1932 init1: 1904 opt: 1904 Z-score: 2099.0 bits: 397.2 E(85289): 3.6e-110
Smith-Waterman score: 1904; 76.9% identity (91.3% similar) in 355 aa overlap (4-358:1-355)
10 20 30 40 50 60
pF1KE1 MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRF
::::.:.::::::::::.:::::::.::: :.::::::::::.::: :::::::.::
XP_016 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRF
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRESLRIALRYYNQSEDGSHTIQ
::::: ::::: ::.:::::.::. .: .::..:::: .:: :: ::::: ::::.:
XP_016 DSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 RMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQW
: :::.:::::.::::.: ::::::::.:::::::::::: .:::::: .:. . ::..
XP_016 GMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 RAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLT
:.::::.:.: ::::::::::::::.: ::.:..:: .::::::::::::.:::::::::
XP_016 RTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 WQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
::::::.::::::::::::::::::::::.:::: :.::::::::::::::.:: ::::
XP_016 WQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSL
: :::::::::.::::..:::..::::::::::.:::::. :::::::. . ..:. :
XP_016 SPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAAYSVVSGNLMIT
300 310 320 330 340 350
pF1KE1 TACKV
XP_016 WWSSLFLLGVLFQGYLGCLRSHSVLGRRKAQLLSVSTSQTSILIQEQFSHQRTLAMSGKM
360 370 380 390 400 410
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:08:15 2016 done: Mon Nov 7 02:08:16 2016
Total Scan time: 7.980 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]