Result of FASTA (omim) for
pFN21AE1563
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1563, 458 aa
1>>>pF1KE1563 458 - 458 aa - 458 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2497+/-0.000339; mu= 18.1821+/- 0.021
mean_var=67.1326+/-13.468, 0's: 0 Z-trim(114.4): 44 B-trim: 10 in 1/56
Lambda= 0.156534
statistics sampled from 24199 (24243) to 24199 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.284), width: 16
Scan time: 8.700
The best scores are: opt bits E(85289)
NP_001299 (OMIM: 212070,603103) carboxypeptidase N ( 458) 3154 721.2 1.4e-207
NP_001864 (OMIM: 114855) carboxypeptidase E prepro ( 476) 1411 327.6 4.4e-89
NP_001014448 (OMIM: 603105) carboxypeptidase Z iso ( 515) 1318 306.6 1e-82
NP_003643 (OMIM: 603105) carboxypeptidase Z isofor ( 641) 1318 306.7 1.2e-82
NP_001014447 (OMIM: 603105) carboxypeptidase Z iso ( 652) 1318 306.7 1.2e-82
NP_062555 (OMIM: 609555) probable carboxypeptidase ( 734) 834 197.4 1.1e-49
NP_001171628 (OMIM: 609555) probable carboxypeptid ( 660) 760 180.7 1e-44
XP_011513464 (OMIM: 602981) PREDICTED: adipocyte e (1132) 685 163.9 2.1e-39
NP_001120 (OMIM: 602981) adipocyte enhancer-bindin (1158) 685 163.9 2.1e-39
NP_001005502 (OMIM: 114860) carboxypeptidase M pre ( 443) 678 162.1 2.8e-39
NP_938079 (OMIM: 114860) carboxypeptidase M precur ( 443) 678 162.1 2.8e-39
NP_001865 (OMIM: 114860) carboxypeptidase M precur ( 443) 678 162.1 2.8e-39
NP_001186704 (OMIM: 603102) carboxypeptidase D iso (1133) 572 138.4 9.9e-32
NP_001295 (OMIM: 603102) carboxypeptidase D isofor (1380) 572 138.4 1.2e-31
NP_057436 (OMIM: 607635) carboxypeptidase A4 isofo ( 421) 193 52.5 2.5e-06
NP_001156918 (OMIM: 607635) carboxypeptidase A4 is ( 388) 183 50.2 1.1e-05
NP_065094 (OMIM: 609562,614417,614418) carboxypept ( 437) 166 46.4 0.00018
XP_011515872 (OMIM: 609562,614417,614418) PREDICTE ( 289) 157 44.3 0.00052
XP_016869135 (OMIM: 609562,614417,614418) PREDICTE ( 289) 157 44.3 0.00052
NP_001861 (OMIM: 114851) mast cell carboxypeptidas ( 417) 148 42.4 0.0029
XP_011515006 (OMIM: 609561) PREDICTED: carboxypept ( 403) 147 42.1 0.0033
NP_001120914 (OMIM: 609561) carboxypeptidase A5 is ( 403) 147 42.1 0.0033
XP_011515005 (OMIM: 609561) PREDICTED: carboxypept ( 436) 147 42.1 0.0035
NP_001120913 (OMIM: 609561) carboxypeptidase A5 is ( 436) 147 42.1 0.0035
XP_011515004 (OMIM: 609561) PREDICTED: carboxypept ( 436) 147 42.1 0.0035
NP_525124 (OMIM: 609561) carboxypeptidase A5 isofo ( 436) 147 42.1 0.0035
XP_011515000 (OMIM: 609561) PREDICTED: carboxypept ( 436) 147 42.1 0.0035
XP_005250769 (OMIM: 609561) PREDICTED: carboxypept ( 436) 147 42.1 0.0035
NP_001305152 (OMIM: 609561) carboxypeptidase A5 is ( 436) 147 42.1 0.0035
XP_011515003 (OMIM: 609561) PREDICTED: carboxypept ( 436) 147 42.1 0.0035
XP_005250767 (OMIM: 609561) PREDICTED: carboxypept ( 436) 147 42.1 0.0035
NP_001860 (OMIM: 600688) carboxypeptidase A2 precu ( 419) 144 41.5 0.0054
>>NP_001299 (OMIM: 212070,603103) carboxypeptidase N cat (458 aa)
initn: 3154 init1: 3154 opt: 3154 Z-score: 3847.8 bits: 721.2 E(85289): 1.4e-207
Smith-Waterman score: 3154; 100.0% identity (100.0% similar) in 458 aa overlap (1-458:1-458)
10 20 30 40 50 60
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
370 380 390 400 410 420
430 440 450
pF1KE1 QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
::::::::::::::::::::::::::::::::::::::
NP_001 QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
430 440 450
>>NP_001864 (OMIM: 114855) carboxypeptidase E preproprot (476 aa)
initn: 1441 init1: 694 opt: 1411 Z-score: 1720.2 bits: 327.6 E(85289): 4.4e-89
Smith-Waterman score: 1411; 53.1% identity (77.5% similar) in 409 aa overlap (21-416:49-450)
10 20 30 40 50
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYS
..:..::: .: ..: .: .: .:.:.:.
NP_001 CGWLLGAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYT
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 IGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNR
.::: :::.: :.:.::.::.::: ::: ::.::::::::.::::.. :...::.:...
NP_001 VGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKG
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 NQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYI
:. ::.::..:::::.::.::::.: ::.: . ..:::.::.:.:::::::::. .
NP_001 NETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIV
140 150 160 170 180 190
180 190 200 210 220
pF1KE1 YYNEKYGGPNHHLPLPDNWK-----SQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYP
: ::: ::::.:: : . : ... :::.:::.:. .. :::::::::: .:::::
NP_001 YVNEKEGGPNNHL-LKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYP
200 210 220 230 240 250
230 240 250 260 270
pF1KE1 YDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQG------WNCGDY-FPDG
:: : : .... .:. ::: .::.::..:: . : . : : : ::
NP_001 YD---ETRSGSAHEYSSS--PDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFVDG
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE1 ITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQV
:::..:::. :::::::: .::::::.::::.:::::: :. : :...::..:::.
NP_001 TTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQI
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE1 HQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPET
:.:.::.: : . : .:::.::: ::.:::::. :::.:::.:: : ..:.:::: :
NP_001 HRGVKGFVRDLQGNPIANATISVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAIT
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE1 VTVTVGPAEPTL-VNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGP
:.: : :. :.:.:.
NP_001 KKVAV-PYSPAAGVDFELESFSERKEEEKEELMEWWKMMSETLNF
440 450 460 470
>>NP_001014448 (OMIM: 603105) carboxypeptidase Z isoform (515 aa)
initn: 1182 init1: 608 opt: 1318 Z-score: 1606.2 bits: 306.6 E(85289): 1e-82
Smith-Waterman score: 1318; 50.3% identity (77.0% similar) in 392 aa overlap (21-406:46-432)
10 20 30 40 50
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYS
. : :: : ..::.: .. ..: ..:.::
NP_001 EDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVLRRTASRCAHVARTYS
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 IGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNR
:::: .::.: :.:::..:: :: .::::: .::.::::. :::... :...:: :.
NP_001 IGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLG
80 90 100 110 120 130
120 130 140 150 160
pF1KE1 NQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNT-Y
: :: .:.. ::::.::::::::::::::.: . :. ::.::...:::::::::.. :
NP_001 NPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEY
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 IYYNEKYGGPNHHLPLPDN-WKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDK
: :. . :.:.:.. : ..: :::.:...::... :::::.:::: .:..::.:
NP_001 YRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDF
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 SFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMF-QGWN-CG-DYFPDG-ITNGAS
: .: .. .::::.:.:. :...:. .: :. .. : :: ... : : :::.
NP_001 S-KH---PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGAD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 WYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKG
:::.. ::.:::::::::::::.::.: :::::: : : :.:.:..:.: ::.::::
NP_001 WYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKG
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE1 MVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG
.: :. . . :: :::.:: ::.:.. :::.::: :::. : : :::: ... ..
NP_001 VVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGY-AKVIKKVII
380 390 400 410 420 430
410 420 430 440 450
pF1KE1 PAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
::
NP_001 PARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPDPLRARRQPSA
440 450 460 470 480 490
>>NP_003643 (OMIM: 603105) carboxypeptidase Z isoform 2 (641 aa)
initn: 1182 init1: 608 opt: 1318 Z-score: 1604.8 bits: 306.7 E(85289): 1.2e-82
Smith-Waterman score: 1318; 50.3% identity (77.0% similar) in 392 aa overlap (21-406:172-558)
10 20 30 40 50
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYS
. : :: : ..::.: .. ..: ..:.::
NP_003 EDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVLRRTASRCAHVARTYS
150 160 170 180 190 200
60 70 80 90 100 110
pF1KE1 IGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNR
:::: .::.: :.:::..:: :: .::::: .::.::::. :::... :...:: :.
NP_003 IGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLG
210 220 230 240 250 260
120 130 140 150 160
pF1KE1 NQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNT-Y
: :: .:.. ::::.::::::::::::::.: . :. ::.::...:::::::::.. :
NP_003 NPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEY
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE1 IYYNEKYGGPNHHLPLPDN-WKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDK
: :. . :.:.:.. : ..: :::.:...::... :::::.:::: .:..::.:
NP_003 YRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDF
330 340 350 360 370 380
230 240 250 260 270 280
pF1KE1 SFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMF-QGWN-CG-DYFPDG-ITNGAS
: .: .. .::::.:.:. :...:. .: :. .. : :: ... : : :::.
NP_003 S-KH---PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGAD
390 400 410 420 430
290 300 310 320 330 340
pF1KE1 WYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKG
:::.. ::.:::::::::::::.::.: :::::: : : :.:.:..:.: ::.::::
NP_003 WYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKG
440 450 460 470 480 490
350 360 370 380 390 400
pF1KE1 MVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG
.: :. . . :: :::.:: ::.:.. :::.::: :::. : : :::: ... ..
NP_003 VVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGY-AKVIKKVII
500 510 520 530 540 550
410 420 430 440 450
pF1KE1 PAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
::
NP_003 PARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPDPLRARRQPSA
560 570 580 590 600 610
>>NP_001014447 (OMIM: 603105) carboxypeptidase Z isoform (652 aa)
initn: 1182 init1: 608 opt: 1318 Z-score: 1604.7 bits: 306.7 E(85289): 1.2e-82
Smith-Waterman score: 1318; 50.3% identity (77.0% similar) in 392 aa overlap (21-406:183-569)
10 20 30 40 50
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYS
. : :: : ..::.: .. ..: ..:.::
NP_001 EDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVLRRTASRCAHVARTYS
160 170 180 190 200 210
60 70 80 90 100 110
pF1KE1 IGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNR
:::: .::.: :.:::..:: :: .::::: .::.::::. :::... :...:: :.
NP_001 IGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLG
220 230 240 250 260 270
120 130 140 150 160
pF1KE1 NQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNT-Y
: :: .:.. ::::.::::::::::::::.: . :. ::.::...:::::::::.. :
NP_001 NPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEY
280 290 300 310 320 330
170 180 190 200 210 220
pF1KE1 IYYNEKYGGPNHHLPLPDN-WKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDK
: :. . :.:.:.. : ..: :::.:...::... :::::.:::: .:..::.:
NP_001 YRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDF
340 350 360 370 380 390
230 240 250 260 270 280
pF1KE1 SFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMF-QGWN-CG-DYFPDG-ITNGAS
: .: .. .::::.:.:. :...:. .: :. .. : :: ... : : :::.
NP_001 S-KH---PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGAD
400 410 420 430 440
290 300 310 320 330 340
pF1KE1 WYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKG
:::.. ::.:::::::::::::.::.: :::::: : : :.:.:..:.: ::.::::
NP_001 WYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKG
450 460 470 480 490 500
350 360 370 380 390 400
pF1KE1 MVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG
.: :. . . :: :::.:: ::.:.. :::.::: :::. : : :::: ... ..
NP_001 VVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGY-AKVIKKVII
510 520 530 540 550 560
410 420 430 440 450
pF1KE1 PAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
::
NP_001 PARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPDPLRARRQPSA
570 580 590 600 610 620
>>NP_062555 (OMIM: 609555) probable carboxypeptidase X1 (734 aa)
initn: 1269 init1: 599 opt: 834 Z-score: 1013.2 bits: 197.4 E(85289): 1.1e-49
Smith-Waterman score: 1299; 48.2% identity (71.7% similar) in 448 aa overlap (20-451:294-730)
10 20 30 40
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVY
:. :.:: : . . . .::..::.:::.:
NP_062 APCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIY
270 280 290 300 310 320
50 60 70 80 90 100
pF1KE1 SIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRN
:::.: .: .:::.:.::.:: :: ::::.::..:::::::::::.: : .:::.::
NP_062 SIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLR
330 340 350 360 370 380
110 120 130 140 150 160
pF1KE1 RNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTY
: :...:... :::.::::::::::.: .: . :. :: : ...:::.:: ::::
NP_062 GNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTP
390 400 410 420 430 440
170 180 190 200 210 220
pF1KE1 IYYNEKYGG-----PNHHLPLPDNW---KSQVEPETRAVIRWMHSFNFVLSANLHGGAVV
.. . : :::::::: . .. : :::::::.::. . :::::::::: .:
NP_062 LWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELV
450 460 470 480 490 500
230 240 250 260 270
pF1KE1 ANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWN---CG--DYFP
..::.: . :. . : :::::: .:. :. ::. .. : : . : :.
NP_062 VSYPFDMT---RTPWAAREL-TPTPDDAVFRWLSTVYAGSNLAM-QDTSRRPCHSQDFSV
510 520 530 540 550
280 290 300 310 320 330
pF1KE1 DG-ITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFL
: : :::.:... .:.::.::::::::.:.:::::::: :.:: .:: .:..::. .:
NP_062 HGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYL
560 570 580 590 600 610
340 350 360 370 380 390
pF1KE1 EQVHQGIKGMVLDENYN-NLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGY
:::..:: :.: :.. . ..:.:::.:.:::::::.. :::.::: :: : :.:.: ::
NP_062 EQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGY
620 630 640 650 660 670
400 410 420 430 440 450
pF1KE1 DPETVTVTVGPAE-PTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQL
: . : : : :: : .. : .: . .. ::: :. :.. ..:
NP_062 HSVTRNCRVTFEEGPFPCNFVLTKT-----PKQRL-RELLAAGAKVPPDLRRRLERLRGQ
680 690 700 710 720 730
pF1KE1 QRGPA
NP_062 KD
>>NP_001171628 (OMIM: 609555) probable carboxypeptidase (660 aa)
initn: 1046 init1: 567 opt: 760 Z-score: 923.6 bits: 180.7 E(85289): 1e-44
Smith-Waterman score: 1047; 43.0% identity (62.2% similar) in 442 aa overlap (20-451:294-656)
10 20 30 40
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVY
:. :.:: : . . . .::..::.:::.:
NP_001 APCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIY
270 280 290 300 310 320
50 60 70 80 90 100
pF1KE1 SIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRN
:::.: .: .:::.:.::.:: :: ::::.::..:::::::::::.: : .:::.::
NP_001 SIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLR
330 340 350 360 370 380
110 120 130 140 150 160
pF1KE1 RNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTY
: :...:... :::.::::::::::.: .: . :. :: : ...:::.:: ::::
NP_001 GNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTP
390 400 410 420 430 440
170 180 190 200 210 220
pF1KE1 IYYNEKYGG-----PNHHLPLPDNW---KSQVEPETRAVIRWMHSFNFVLSANLHGGAVV
.. . : :::::::: . .. : :::::::.::. . ::::::::::
NP_001 LWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGG---
450 460 470 480 490 500
230 240 250 260 270 280
pF1KE1 ANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITN
NP_001 ------------------------------------------------------------
290 300 310 320 330 340
pF1KE1 GASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQG
:.::.::::::::.:.:::::::: :.:: .:: .:..::. .::::..:
NP_001 ----------MNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMG
510 520 530 540 550
350 360 370 380 390 400
pF1KE1 IKGMVLDENYN-NLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVT
: :.: :.. . ..:.:::.:.:::::::.. :::.::: :: : :.:.: :: : .
NP_001 IAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRN
560 570 580 590 600 610
410 420 430 440 450
pF1KE1 VTVGPAE-PTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
: : : :: : .. : .: . .. ::: :. :.. ..:
NP_001 CRVTFEEGPFPCNFVLTKT-----PKQRL-RELLAAGAKVPPDLRRRLERLRGQKD
620 630 640 650 660
>>XP_011513464 (OMIM: 602981) PREDICTED: adipocyte enhan (1132 aa)
initn: 1160 init1: 540 opt: 685 Z-score: 828.6 bits: 163.9 E(85289): 2.1e-39
Smith-Waterman score: 1168; 43.4% identity (66.7% similar) in 468 aa overlap (23-444:536-1002)
10 20 30 40 50
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNE-CPGITRVYSI
:::: : :. : :.:: :: :: :::.::.
XP_011 CMRLEVLGCSVAPVYSYYAQNEVVATDDLDFRHHSYKDM-RQLMKVVNEECPTITRTYSL
510 520 530 540 550 560
60 70 80 90 100 110
pF1KE1 GRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRN
:.: .: ..:..:.::.:: :: ::: .:....::::.:::::.: : ..::.:.:. :
XP_011 GKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGN
570 580 590 600 610 620
120 130 140 150 160 170
pF1KE1 QRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIY
:. .:.::::::..::.::::::::: .: . .. .: . .: :. ..:::::. ..
XP_011 PRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLW
630 640 650 660 670 680
180 190 200 210 220
pF1KE1 YNEK-----YGGPNHHLPLPDNWKSQ---VEPETRAVIRWMHSFNFVLSANLHGGAVVAN
:. : ::..::.:. . : : :.::.: ::.. :::.:::.:: ...
XP_011 GAEERKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVS
690 700 710 720 730 740
230 240 250 260
pF1KE1 YPYDKSFEHR-----------VRGVRR---TASTPTPDDKLFQKLAKVYSYAHGWMFQGW
:::: . .:: . . . ::: .:. :: .. :: . . .
XP_011 YPYDMARTPTQEQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPY
750 760 770 780 790 800
270 280 290 300 310 320
pF1KE1 NCG----DYFPD-GITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREW
: :: ::.:::.: . ..::.::::::.:... :.::::: : :: :::
XP_011 RGGCQAQDYTGGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREW
810 820 830 840 850 860
330 340 350 360 370 380
pF1KE1 LGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGI
.:.:::. :.::::.::::.: ::. .:::.:::::::: : ... :::.:.: ::
XP_011 ENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGE
870 880 890 900 910 920
390 400 410 420
pF1KE1 YTVSATAPGYDPETVTVTVG-PAEPTLVNFHLKRS----------------IPQVSPVR-
: :.: : :: : . : .: : :: : :: ::...: :
XP_011 YRVTAHAEGYTPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRP
930 940 950 960 970 980
430 440 450
pF1KE1 RAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
.:..:. . ..: . :
XP_011 MTPQQRRLQQRRLQHRLRLRAQMRLRRLNATTTLGPHTVPPTLPPAPATTLSTTIEPWGL
990 1000 1010 1020 1030 1040
>>NP_001120 (OMIM: 602981) adipocyte enhancer-binding pr (1158 aa)
initn: 1160 init1: 540 opt: 685 Z-score: 828.5 bits: 163.9 E(85289): 2.1e-39
Smith-Waterman score: 1168; 43.4% identity (66.7% similar) in 468 aa overlap (23-444:562-1028)
10 20 30 40 50
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNE-CPGITRVYSI
:::: : :. : :.:: :: :: :::.::.
NP_001 CMRLEVLGCSVAPVYSYYAQNEVVATDDLDFRHHSYKDM-RQLMKVVNEECPTITRTYSL
540 550 560 570 580 590
60 70 80 90 100 110
pF1KE1 GRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRN
:.: .: ..:..:.::.:: :: ::: .:....::::.:::::.: : ..::.:.:. :
NP_001 GKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGN
600 610 620 630 640 650
120 130 140 150 160 170
pF1KE1 QRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIY
:. .:.::::::..::.::::::::: .: . .. .: . .: :. ..:::::. ..
NP_001 PRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLW
660 670 680 690 700 710
180 190 200 210 220
pF1KE1 YNEK-----YGGPNHHLPLPDNWKSQ---VEPETRAVIRWMHSFNFVLSANLHGGAVVAN
:. : ::..::.:. . : : :.::.: ::.. :::.:::.:: ...
NP_001 GAEERKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVS
720 730 740 750 760 770
230 240 250 260
pF1KE1 YPYDKSFEHR-----------VRGVRR---TASTPTPDDKLFQKLAKVYSYAHGWMFQGW
:::: . .:: . . . ::: .:. :: .. :: . . .
NP_001 YPYDMARTPTQEQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPY
780 790 800 810 820 830
270 280 290 300 310 320
pF1KE1 NCG----DYFPD-GITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREW
: :: ::.:::.: . ..::.::::::.:... :.::::: : :: :::
NP_001 RGGCQAQDYTGGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREW
840 850 860 870 880 890
330 340 350 360 370 380
pF1KE1 LGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGI
.:.:::. :.::::.::::.: ::. .:::.:::::::: : ... :::.:.: ::
NP_001 ENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGE
900 910 920 930 940 950
390 400 410 420
pF1KE1 YTVSATAPGYDPETVTVTVG-PAEPTLVNFHLKRS----------------IPQVSPVR-
: :.: : :: : . : .: : :: : :: ::...: :
NP_001 YRVTAHAEGYTPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRP
960 970 980 990 1000 1010
430 440 450
pF1KE1 RAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
.:..:. . ..: . :
NP_001 MTPQQRRLQQRRLQHRLRLRAQMRLRRLNATTTLGPHTVPPTLPPAPATTLSTTIEPWGL
1020 1030 1040 1050 1060 1070
>>NP_001005502 (OMIM: 114860) carboxypeptidase M precurs (443 aa)
initn: 1047 init1: 364 opt: 678 Z-score: 826.1 bits: 162.1 E(85289): 2.8e-39
Smith-Waterman score: 1049; 43.5% identity (69.5% similar) in 416 aa overlap (9-419:6-392)
10 20 30 40 50 60
pF1KE1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
: : ::. ::: . : .:: . . : : .. ..:...:::.::.::.:
NP_001 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNL
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
.:: . : :. :: :::.::::.:..::::.:.: ..: ... .:..::..
NP_001 WVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
:::::.:::::::.: :.. :. : .::.: : :::::::: :
NP_001 TRIHIMPSMNPDGFE--AVKKPDCY-YSIGRENYNQYDLNRNFPDAFEY-----------
120 130 140 150 160
190 200 210 220 230 240
pF1KE1 HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
.: . : ::: ::..:... .:::::::::::.::.::.:.. . . :. .
NP_001 ------NNVSRQ--PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ--ATGALYS
170 180 190 200 210
250 260 270 280 290
pF1KE1 ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYL
: :::: .:: ::..:. . : .: .: . ::.:.::: ::: :. ::::.::.
NP_001 RSL-TPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYI
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 HTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAV
..:::::::::: :.: ::.: : .:. .::....::: :.::.:.:.: : : :..
NP_001 WAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVI
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 ISVSGINH--DVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFH-L
. :. .: .. .:.:. ::::: : ...:.::.::. .: .. : . :: :
NP_001 VEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPH-ITKVIIPEKSQ--NFSAL
340 350 360 370 380
420 430 440 450
pF1KE1 KRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
:..:
NP_001 KKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSLLHIFFK
390 400 410 420 430 440
458 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:32:43 2016 done: Mon Nov 7 15:32:44 2016
Total Scan time: 8.700 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]