Result of FASTA (omim) for
pFN21AE1555
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1555, 153 aa
1>>>pF1KE1555 153 - 153 aa - 153 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7106+/-0.000321; mu= 15.3995+/- 0.020
mean_var=59.0766+/-12.226, 0's: 0 Z-trim(115.7): 52 B-trim: 1586 in 1/48
Lambda= 0.166866
statistics sampled from 26342 (26395) to 26342 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.309), width: 16
Scan time: 4.140
The best scores are: opt bits E(85289)
NP_005425 (OMIM: 602022) MAL-like protein [Homo sa ( 153) 1003 249.1 2.1e-66
XP_011510111 (OMIM: 602022) PREDICTED: MAL-like pr ( 149) 771 193.2 1.3e-49
NP_002362 (OMIM: 188860) myelin and lymphocyte pro ( 153) 396 103.0 2e-22
NP_443118 (OMIM: 609684) protein MAL2 [Homo sapien ( 176) 293 78.2 6.6e-15
NP_071883 (OMIM: 188860) myelin and lymphocyte pro ( 111) 248 67.2 8.4e-12
NP_849199 (OMIM: 607891) CKLF-like MARVEL transmem ( 173) 232 63.5 1.7e-10
XP_011531718 (OMIM: 607891) PREDICTED: CKLF-like M ( 196) 217 59.9 2.3e-09
XP_016861268 (OMIM: 607891) PREDICTED: CKLF-like M ( 130) 212 58.6 3.8e-09
NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens ( 182) 201 56.1 3.1e-08
NP_071884 (OMIM: 188860) myelin and lymphocyte pro ( 97) 158 45.5 2.5e-05
XP_016861269 (OMIM: 607891) PREDICTED: CKLF-like M ( 100) 139 41.0 0.00061
>>NP_005425 (OMIM: 602022) MAL-like protein [Homo sapien (153 aa)
initn: 1003 init1: 1003 opt: 1003 Z-score: 1313.2 bits: 249.1 E(85289): 2.1e-66
Smith-Waterman score: 1003; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153)
10 20 30 40 50 60
pF1KE1 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL
70 80 90 100 110 120
130 140 150
pF1KE1 LDPRIYYINSAASFFAFIATLLYILHAFSIYYH
:::::::::::::::::::::::::::::::::
NP_005 LDPRIYYINSAASFFAFIATLLYILHAFSIYYH
130 140 150
>>XP_011510111 (OMIM: 602022) PREDICTED: MAL-like protei (149 aa)
initn: 771 init1: 771 opt: 771 Z-score: 1011.5 bits: 193.2 E(85289): 1.3e-49
Smith-Waterman score: 771; 100.0% identity (100.0% similar) in 119 aa overlap (35-153:31-149)
10 20 30 40 50 60
pF1KE1 DPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVMYVSL
::::::::::::::::::::::::::::::
XP_011 MEKLTEDSRKKKKGAGIFGKETRIQNTTKLLIFGFLVWTMVAATHIVYPLLQGWVMYVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKLLDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKLLDPR
70 80 90 100 110 120
130 140 150
pF1KE1 IYYINSAASFFAFIATLLYILHAFSIYYH
:::::::::::::::::::::::::::::
XP_011 IYYINSAASFFAFIATLLYILHAFSIYYH
130 140
>>NP_002362 (OMIM: 188860) myelin and lymphocyte protein (153 aa)
initn: 393 init1: 393 opt: 396 Z-score: 523.5 bits: 103.0 E(85289): 2e-22
Smith-Waterman score: 396; 42.8% identity (73.8% similar) in 145 aa overlap (7-150:3-147)
10 20 30 40 50 60
pF1KE1 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVM
::.. . : .::: ..: :.: .:. :.::: ::: .::.. . .::.:::::
NP_002 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVM
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL
.::. :. . ... :..: . :: .::. :: :....:.::.::.. :::. .
NP_002 FVSVFCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDG
60 70 80 90 100 110
130 140 150
pF1KE1 LDPRIYYINSAASFFAFIATLLYILHA-FSIYYH
. : :. : :: :..::::::..:: ::.
NP_002 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
120 130 140 150
>>NP_443118 (OMIM: 609684) protein MAL2 [Homo sapiens] (176 aa)
initn: 262 init1: 197 opt: 293 Z-score: 388.6 bits: 78.2 E(85289): 6.6e-15
Smith-Waterman score: 337; 40.5% identity (66.0% similar) in 153 aa overlap (4-143:11-163)
10 20 30 40 50
pF1KE1 MASPDPPATSYAPSDV--PSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIV
: ::.:. : : :.: .. : :: :..:: ::: .::....
NP_443 MSAGGASVPPPPNPAVSFPPPRVTLPAGPDILRTYSGAFVCLEILFGGLVWILVASSNVP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 YPLLQGWVMYVSLTSFLISLMFLLSYLFGFYKRFES-WRVLDSLYHGTTGILYMSAAVLQ
::::::::.::.:.:..::.:: .: :. .... : :: :: :. ..:..: .:.
NP_443 LPLLQGWVMFVSVTAFFFSLLFLGMFLSGMVAQIDANWNFLDFAYHFTVFVFYFGAFLLE
70 80 90 100 110 120
120 130 140 150
pF1KE1 VHAT----------IVSEKLLDPRIYYINSAASFFAFIATLLYILHAFSIYYH
. :: :... ::. : :: :::.:::..: :
NP_443 AAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTACYGCSLGLALRRWRP
130 140 150 160 170
>>NP_071883 (OMIM: 188860) myelin and lymphocyte protein (111 aa)
initn: 291 init1: 239 opt: 248 Z-score: 332.9 bits: 67.2 E(85289): 8.4e-12
Smith-Waterman score: 248; 38.1% identity (69.5% similar) in 105 aa overlap (7-111:3-105)
10 20 30 40 50 60
pF1KE1 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVM
::.. . : .::: ..: :.: .:. :.::: ::: .::.. . .::.:::::
NP_071 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVM
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL
.::. :. . ... :..: . :: .: : .: .::. ::...
NP_071 FVSVFCFVATTTLIILYIIGAHGGETSWVTLVFSYIAT--LLYVVHAVFSLIRWKSS
60 70 80 90 100 110
130 140 150
pF1KE1 LDPRIYYINSAASFFAFIATLLYILHAFSIYYH
>>NP_849199 (OMIM: 607891) CKLF-like MARVEL transmembran (173 aa)
initn: 190 init1: 132 opt: 232 Z-score: 309.4 bits: 63.5 E(85289): 1.7e-10
Smith-Waterman score: 232; 34.7% identity (68.5% similar) in 124 aa overlap (23-143:36-156)
10 20 30 40 50
pF1KE1 MASPDPPATSYAPSDVPSGVALFL-TIPFAFFLPELIFGFLVWTMVAATHIV
:: :.: ... :...:.::::..:.:.
NP_849 RARSHTVTTTASSFAENFSTSSSSFAYDREFLRTLPGFLIVAEIVLGLLVWTLIAGTEYF
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 YPLLQGWVMYVSLTSFLISLMFLLSYLFGFYKRFES--WRVLDSLYHGTTGILYMSAAVL
::::.:.. ......::. :. : :. . : .. ..:.. .::.::::
NP_849 RVPAFGWVMFVAVFYWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYLSAAV-
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 QVHATIVSEKLLDPRIYYINSAASFFAFIATLLYILHAFSIYYH
: :. :: . : . . .:.:::::..:. :
NP_849 -VDASSVSPER-DSHNFNSWAASSFFAFLVTICYAGNTYFSFIAWRSRTIQ
130 140 150 160 170
>>XP_011531718 (OMIM: 607891) PREDICTED: CKLF-like MARVE (196 aa)
initn: 186 init1: 128 opt: 217 Z-score: 289.1 bits: 59.9 E(85289): 2.3e-09
Smith-Waterman score: 217; 35.1% identity (68.5% similar) in 111 aa overlap (35-143:72-179)
10 20 30 40 50 60
pF1KE1 DPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVMYVSL
:..:.::::..:.:. ::::.:..
XP_011 GFLIVAEILISLPITDPLHRSALSTTARDILVLGLLVWTLIAGTEYFRVPAFGWVMFVAV
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE1 TSFLISLMFLLSYLFGFYKRFES--WRVLDSLYHGTTGILYMSAAVLQVHATIVSEKLLD
......::. :. : :. . : .. ..:.. .::.:::: : :. :: . :
XP_011 FYWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYLSAAV--VDASSVSPER-D
110 120 130 140 150
130 140 150
pF1KE1 PRIYYINSAASFFAFIATLLYILHAFSIYYH
. . .:.:::::..:. :
XP_011 SHNFNSWAASSFFAFLVTICYAGNTYFSFIAWRSRTIQ
160 170 180 190
>>XP_016861268 (OMIM: 607891) PREDICTED: CKLF-like MARVE (130 aa)
initn: 181 init1: 123 opt: 212 Z-score: 285.1 bits: 58.6 E(85289): 3.8e-09
Smith-Waterman score: 212; 34.5% identity (68.2% similar) in 110 aa overlap (36-143:7-113)
10 20 30 40 50 60
pF1KE1 PPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAATHIVYPLLQGWVMYVSLT
..:.::::..:.:. ::::.:..
XP_016 MFRRIQVLGLLVWTLIAGTEYFRVPAFGWVMFVAVF
10 20 30
70 80 90 100 110 120
pF1KE1 SFLISLMFLLSYLFGFYKRFES--WRVLDSLYHGTTGILYMSAAVLQVHATIVSEKLLDP
......::. :. : :. . : .. ..:.. .::.:::: : :. :: . :
XP_016 YWVLTVFFLIIYITMTYTRIPQVPWTTVGLCFNGSAFVLYLSAAV--VDASSVSPER-DS
40 50 60 70 80 90
130 140 150
pF1KE1 RIYYINSAASFFAFIATLLYILHAFSIYYH
. . .:.:::::..:. :
XP_016 HNFNSWAASSFFAFLVTICYAGNTYFSFIAWRSRTIQ
100 110 120 130
>>NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens] (182 aa)
initn: 164 init1: 125 opt: 201 Z-score: 268.7 bits: 56.1 E(85289): 3.1e-08
Smith-Waterman score: 201; 30.2% identity (65.1% similar) in 126 aa overlap (29-151:39-162)
10 20 30 40 50
pF1KE1 MASPDPPATSYAPSDVPSGVALFLTIPFAFFLPELIFGFLVWTMVAAT-HIVYPLLQG
:..: .:..:.:::...: : . .:: :
NP_057 STRTSSPAQGAEASVSALRPDLGFVRSRLGALMLLQLVLGLLVWALIADTPYHLYPAY-G
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 WVMYVSLTSFLISLMFLLSYLFGFYKRFE--SWRVLDSLYHGTTGILYMSAAVLQVHATI
:::.:.. .:...... ::: .. .. : .. ... .. .::..: . :..
NP_057 WVMFVAVFLWLVTIVLFNLYLFQLHMKLYMVPWPLVLMIFNISATVLYITAFI-ACSAAV
70 80 90 100 110 120
120 130 140 150
pF1KE1 VSEKLLDPRIYYINSAASFFAFIATLLYILHAFSIYYH
.: : : .:::::: .. . : . :: :
NP_057 DLTSLRGTRPYNQRAAASFFACLVMIAYGVSAFFSYQAWRGVGSNAATSQMAGGYA
130 140 150 160 170 180
>>NP_071884 (OMIM: 188860) myelin and lymphocyte protein (97 aa)
initn: 216 init1: 155 opt: 158 Z-score: 216.6 bits: 45.5 E(85289): 2.5e-05
Smith-Waterman score: 158; 45.9% identity (77.0% similar) in 61 aa overlap (91-150:31-91)
70 80 90 100 110 120
pF1KE1 YVSLTSFLISLMFLLSYLFGFYKRFESWRVLDSLYHGTTGILYMSAAVLQVHATIVSEKL
.:. :: :....:.::.::.. :::. .
NP_071 MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFDAAYHCTAALFYLSASVLEALATITMQDG
10 20 30 40 50 60
130 140 150
pF1KE1 LDPRIYYINSAASFFAFIATLLYILHA-FSIYYH
. : :. : :: :..::::::..:: ::.
NP_071 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
70 80 90
153 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:32:13 2016 done: Mon Nov 7 02:32:14 2016
Total Scan time: 4.140 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]