Result of FASTA (omim) for
pFN21AE1538
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1538, 117 aa
1>>>pF1KE1538 117 - 117 aa - 117 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4413+/-0.000273; mu= 11.0291+/- 0.017
mean_var=80.8667+/-15.841, 0's: 0 Z-trim(120.7): 26 B-trim: 66 in 1/56
Lambda= 0.142623
statistics sampled from 36328 (36354) to 36328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.426), width: 16
Scan time: 4.820
The best scores are: opt bits E(85289)
NP_002629 (OMIM: 182257) elafin preproprotein [Hom ( 117) 813 175.5 1.7e-44
NP_003055 (OMIM: 107285) antileukoproteinase precu ( 132) 210 51.5 4.3e-07
XP_011526904 (OMIM: 605161) PREDICTED: WAP four-di ( 123) 174 44.0 6.9e-05
NP_663627 (OMIM: 605161) WAP four-disulfide core d ( 123) 174 44.0 6.9e-05
XP_011526903 (OMIM: 605161) PREDICTED: WAP four-di ( 123) 174 44.0 6.9e-05
NP_543145 (OMIM: 609872) WAP four-disulfide core d ( 111) 166 42.3 0.0002
>>NP_002629 (OMIM: 182257) elafin preproprotein [Homo sa (117 aa)
initn: 813 init1: 813 opt: 813 Z-score: 919.6 bits: 175.5 E(85289): 1.7e-44
Smith-Waterman score: 813; 100.0% identity (100.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KE1 MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVK
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 AQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ
70 80 90 100 110
>>NP_003055 (OMIM: 107285) antileukoproteinase precursor (132 aa)
initn: 315 init1: 192 opt: 210 Z-score: 248.4 bits: 51.5 E(85289): 4.3e-07
Smith-Waterman score: 216; 33.8% identity (52.3% similar) in 130 aa overlap (1-116:1-129)
10 20 30 40
pF1KE1 MRASSFLIVVVFLIAGTLVLEAAV-------TGV--PVKGQDTVKGRVPFNGQD---PVK
:..:... .:.: :::. :. .:: : :. . .. . : .: : :
NP_003 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 GQVSVKGQDKVKAQEPVKGPVST--KPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCE
. .: .:: : : :::.::. .: :::::: : : .: :::
NP_003 KRCC-PDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCM
70 80 90 100 110
110
pF1KE1 GSCGMACFVPQ
: :: .: :
NP_003 GMCGKSCVSPVKA
120 130
>>XP_011526904 (OMIM: 605161) PREDICTED: WAP four-disulf (123 aa)
initn: 224 init1: 107 opt: 174 Z-score: 208.8 bits: 44.0 E(85289): 6.9e-05
Smith-Waterman score: 176; 35.4% identity (54.6% similar) in 130 aa overlap (1-116:1-120)
10 20 30 40 50 60
pF1KE1 MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVK
::..:.:.. ..: .:. . :: : ::. . : : .: : .:: :
XP_011 MRTQSLLLLGALLAVGSQL--PAVFGRK-KGEKS-GGCPPDDG--PC--LLSVPDQCVED
10 20 30 40 50
70 80 90 100
pF1KE1 AQEPVKG------------P-VSTKPGSCPIILIRCAMLNPPNR-CLKDTDCPGIKKCCE
.: :. : ::.: :::: .:: :.: :. : ::.:: : :.::.
XP_011 SQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRC--LSPMNHLCHKDSDCSGKKRCCH
60 70 80 90 100 110
110
pF1KE1 GSCGMACFVPQ
..:: : :
XP_011 SACGRDCRDPARG
120
>>NP_663627 (OMIM: 605161) WAP four-disulfide core domai (123 aa)
initn: 224 init1: 107 opt: 174 Z-score: 208.8 bits: 44.0 E(85289): 6.9e-05
Smith-Waterman score: 176; 35.4% identity (54.6% similar) in 130 aa overlap (1-116:1-120)
10 20 30 40 50 60
pF1KE1 MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVK
::..:.:.. ..: .:. . :: : ::. . : : .: : .:: :
NP_663 MRTQSLLLLGALLAVGSQL--PAVFGRK-KGEKS-GGCPPDDG--PC--LLSVPDQCVED
10 20 30 40 50
70 80 90 100
pF1KE1 AQEPVKG------------P-VSTKPGSCPIILIRCAMLNPPNR-CLKDTDCPGIKKCCE
.: :. : ::.: :::: .:: :.: :. : ::.:: : :.::.
NP_663 SQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRC--LSPMNHLCHKDSDCSGKKRCCH
60 70 80 90 100 110
110
pF1KE1 GSCGMACFVPQ
..:: : :
NP_663 SACGRDCRDPARG
120
>>XP_011526903 (OMIM: 605161) PREDICTED: WAP four-disulf (123 aa)
initn: 224 init1: 107 opt: 174 Z-score: 208.8 bits: 44.0 E(85289): 6.9e-05
Smith-Waterman score: 176; 35.4% identity (54.6% similar) in 130 aa overlap (1-116:1-120)
10 20 30 40 50 60
pF1KE1 MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVK
::..:.:.. ..: .:. . :: : ::. . : : .: : .:: :
XP_011 MRTQSLLLLGALLAVGSQL--PAVFGRK-KGEKS-GGCPPDDG--PC--LLSVPDQCVED
10 20 30 40 50
70 80 90 100
pF1KE1 AQEPVKG------------P-VSTKPGSCPIILIRCAMLNPPNR-CLKDTDCPGIKKCCE
.: :. : ::.: :::: .:: :.: :. : ::.:: : :.::.
XP_011 SQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRC--LSPMNHLCHKDSDCSGKKRCCH
60 70 80 90 100 110
110
pF1KE1 GSCGMACFVPQ
..:: : :
XP_011 SACGRDCRDPARG
120
>>NP_543145 (OMIM: 609872) WAP four-disulfide core domai (111 aa)
initn: 216 init1: 95 opt: 166 Z-score: 200.5 bits: 42.3 E(85289): 0.0002
Smith-Waterman score: 166; 42.9% identity (55.4% similar) in 56 aa overlap (61-116:20-73)
40 50 60 70 80 90
pF1KE1 GQDTVKGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAMLNPPN
: : :: . : : :: .:: .::
NP_543 MGSSSFLVLMVSLVLVTLVAVEGVKEGIE-KAGVCPADNVRCFKSDPP-
10 20 30 40
100 110
pF1KE1 RCLKDTDCPGIKKCCEGSCGMACFVPQ
.: : :: : .::: ::. : .:
NP_543 QCHTDQDCLGERKCCYLHCGFKCVIPVKELEEGGNKDEDVSRPYPEPGWEAKCPGSSSTR
50 60 70 80 90 100
117 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:52:52 2016 done: Mon Nov 7 01:52:53 2016
Total Scan time: 4.820 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]