FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1522, 592 aa
  1>>>pF1KE1522 592 - 592 aa - 592 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4975+/-0.00048; mu= 18.0318+/- 0.030
 mean_var=71.2121+/-14.074, 0's: 0 Z-trim(108.7): 19  B-trim: 256 in 2/50
 Lambda= 0.151984
 statistics sampled from 16765 (16767) to 16765 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.197), width:  16
 Scan time: 10.290

The best scores are:                                      opt bits E(85289)
NP_004035 (OMIM: 601731,608688) bifunctional purin ( 592) 3834 850.6       0
XP_016859676 (OMIM: 601731,608688) PREDICTED: bifu ( 557) 3583 795.6       0


>>NP_004035 (OMIM: 601731,608688) bifunctional purine bi  (592 aa)
 initn: 3834 init1: 3834 opt: 3834  Z-score: 4543.1  bits: 850.6 E(85289):    0
Smith-Waterman score: 3834; 100.0% identity (100.0% similar) in 592 aa overlap (1-592:1-592)

               10        20        30        40        50        60
pF1KE1 MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
              490       500       510       520       530       540

              550       560       570       580       590  
pF1KE1 FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
              550       560       570       580       590  

>>XP_016859676 (OMIM: 601731,608688) PREDICTED: bifuncti  (557 aa)
 initn: 3583 init1: 3583 opt: 3583  Z-score: 4246.0  bits: 795.6 E(85289):    0
Smith-Waterman score: 3583; 100.0% identity (100.0% similar) in 553 aa overlap (1-553:1-553)

               10        20        30        40        50        60
pF1KE1 MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
              490       500       510       520       530       540

              550       560       570       580       590  
pF1KE1 FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
       :::::::::::::                                       
XP_016 FFPFRDNVDRAKRISRL                                   
              550                                          




592 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 02:05:50 2016 done: Mon Nov  7 02:05:52 2016
 Total Scan time: 10.290 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]