Result of FASTA (omim) for
pFN21AE1519
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1519, 464 aa
1>>>pF1KE1519 464 - 464 aa - 464 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.1645+/-0.000578; mu= -33.8158+/- 0.036
mean_var=1044.3263+/-219.469, 0's: 0 Z-trim(125.1): 223 B-trim: 934 in 1/61
Lambda= 0.039688
statistics sampled from 47923 (48199) to 47923 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.565), width: 16
Scan time: 9.930
The best scores are: opt bits E(85289)
NP_009096 (OMIM: 600796) splicing factor 3A subuni ( 464) 3479 214.5 5e-55
XP_016857330 (OMIM: 606373,616193) PREDICTED: form (1102) 636 52.1 9.1e-06
XP_016857329 (OMIM: 606373,616193) PREDICTED: form (1102) 636 52.1 9.1e-06
XP_016857328 (OMIM: 606373,616193) PREDICTED: form (1159) 636 52.1 9.4e-06
XP_011542539 (OMIM: 606373,616193) PREDICTED: form (1360) 636 52.2 1.1e-05
XP_016857327 (OMIM: 606373,616193) PREDICTED: form (1384) 636 52.2 1.1e-05
XP_016857326 (OMIM: 606373,616193) PREDICTED: form (1417) 636 52.2 1.1e-05
NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 (1722) 636 52.3 1.2e-05
NP_001292353 (OMIM: 606373,616193) formin-2 isofor (1726) 636 52.3 1.2e-05
NP_005030 (OMIM: 180989) basic salivary proline-ri ( 331) 518 44.8 0.00043
NP_006239 (OMIM: 168810) basic salivary proline-ri ( 416) 513 44.6 0.00062
NP_061939 (OMIM: 176270,605283,615547) MAGE-like p (1249) 524 45.7 0.00085
NP_006240 (OMIM: 168840) basic salivary proline-ri ( 309) 495 43.4 0.001
NP_000928 (OMIM: 180660) DNA-directed RNA polymera (1970) 495 44.3 0.0036
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 491 44.1 0.0044
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 491 44.1 0.0044
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 491 44.1 0.0044
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 491 44.1 0.0044
NP_008938 (OMIM: 604979) cleavage and polyadenylat ( 551) 456 41.5 0.0072
XP_005268647 (OMIM: 604979) PREDICTED: cleavage an ( 552) 456 41.5 0.0072
NP_001092872 (OMIM: 603544) cyclin-K [Homo sapiens ( 580) 450 41.1 0.0095
XP_005268211 (OMIM: 603544) PREDICTED: cyclin-K is ( 580) 450 41.1 0.0095
XP_011535577 (OMIM: 603544) PREDICTED: cyclin-K is ( 580) 450 41.1 0.0095
>>NP_009096 (OMIM: 600796) splicing factor 3A subunit 2 (464 aa)
initn: 3479 init1: 3479 opt: 3479 Z-score: 1108.9 bits: 214.5 E(85289): 5e-55
Smith-Waterman score: 3479; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)
10 20 30 40 50 60
pF1KE1 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPEKVKVEVKKFVKIGRPGYKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPEKVKVEVKKFVKIGRPGYKVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KQRDSEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KQRDSEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 APGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 APGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPG
370 380 390 400 410 420
430 440 450 460
pF1KE1 VHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN
::::::::::::::::::::::::::::::::::::::::::::
NP_009 VHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN
430 440 450 460
>>XP_016857330 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 627 init1: 321 opt: 636 Z-score: 224.5 bits: 52.1 E(85289): 9.1e-06
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:257-591)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
XP_016 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
230 240 250 260 270 280
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
XP_016 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
290 300 310 320 330 340
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
XP_016 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
350 360 370 380 390 400
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
XP_016 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
410 420 430 440 450 460
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
XP_016 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
470 480 490 500 510 520
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
XP_016 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
530 540 550 560 570 580
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
XP_016 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
590 600 610 620 630 640
>>XP_016857329 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 627 init1: 321 opt: 636 Z-score: 224.5 bits: 52.1 E(85289): 9.1e-06
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:257-591)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
XP_016 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
230 240 250 260 270 280
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
XP_016 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
290 300 310 320 330 340
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
XP_016 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
350 360 370 380 390 400
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
XP_016 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
410 420 430 440 450 460
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
XP_016 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
470 480 490 500 510 520
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
XP_016 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
530 540 550 560 570 580
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
XP_016 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
590 600 610 620 630 640
>>XP_016857328 (OMIM: 606373,616193) PREDICTED: formin-2 (1159 aa)
initn: 627 init1: 321 opt: 636 Z-score: 224.2 bits: 52.1 E(85289): 9.4e-06
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:314-648)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
XP_016 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
290 300 310 320 330 340
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
XP_016 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
350 360 370 380 390 400
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
XP_016 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
410 420 430 440 450 460
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
XP_016 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
470 480 490 500 510 520
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
XP_016 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
530 540 550 560 570
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
XP_016 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
580 590 600 610 620 630
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
XP_016 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
640 650 660 670 680 690
>>XP_011542539 (OMIM: 606373,616193) PREDICTED: formin-2 (1360 aa)
initn: 627 init1: 321 opt: 636 Z-score: 223.4 bits: 52.2 E(85289): 1.1e-05
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:881-1215)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
XP_011 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
860 870 880 890 900 910
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
XP_011 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
920 930 940 950 960 970
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
XP_011 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
980 990 1000 1010 1020
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
XP_011 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
1030 1040 1050 1060 1070 1080
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
XP_011 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
1090 1100 1110 1120 1130 1140
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
XP_011 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
1150 1160 1170 1180 1190 1200
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
XP_011 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
1210 1220 1230 1240 1250 1260
>>XP_016857327 (OMIM: 606373,616193) PREDICTED: formin-2 (1384 aa)
initn: 627 init1: 321 opt: 636 Z-score: 223.3 bits: 52.2 E(85289): 1.1e-05
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:881-1215)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
XP_016 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
860 870 880 890 900 910
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
XP_016 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
920 930 940 950 960 970
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
XP_016 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
980 990 1000 1010 1020
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
XP_016 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
1030 1040 1050 1060 1070 1080
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
XP_016 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
1090 1100 1110 1120 1130 1140
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
XP_016 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
1150 1160 1170 1180 1190 1200
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
XP_016 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
1210 1220 1230 1240 1250 1260
>>XP_016857326 (OMIM: 606373,616193) PREDICTED: formin-2 (1417 aa)
initn: 627 init1: 321 opt: 636 Z-score: 223.2 bits: 52.2 E(85289): 1.1e-05
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:881-1215)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
XP_016 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
860 870 880 890 900 910
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
XP_016 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
920 930 940 950 960 970
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
XP_016 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
980 990 1000 1010 1020
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
XP_016 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
1030 1040 1050 1060 1070 1080
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
XP_016 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
1090 1100 1110 1120 1130 1140
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
XP_016 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
1150 1160 1170 1180 1190 1200
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
XP_016 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
1210 1220 1230 1240 1250 1260
>>NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 [Ho (1722 aa)
initn: 627 init1: 321 opt: 636 Z-score: 222.1 bits: 52.3 E(85289): 1.2e-05
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:877-1211)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
NP_064 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
850 860 870 880 890 900
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
NP_064 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
910 920 930 940 950 960
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
NP_064 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
970 980 990 1000 1010 1020
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
NP_064 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
1030 1040 1050 1060 1070 1080
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
NP_064 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
1090 1100 1110 1120 1130 1140
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
NP_064 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
1150 1160 1170 1180 1190 1200
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
NP_064 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
1210 1220 1230 1240 1250 1260
>>NP_001292353 (OMIM: 606373,616193) formin-2 isoform 1 (1726 aa)
initn: 627 init1: 321 opt: 636 Z-score: 222.1 bits: 52.3 E(85289): 1.2e-05
Smith-Waterman score: 695; 38.8% identity (49.7% similar) in 340 aa overlap (217-462:881-1215)
190 200 210 220 230 240
pF1KE1 EIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAG--P--PGVKRPPPPLMNGL-
:: :: ::. : :.. : :: ..:
NP_001 SAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE
860 870 880 890 900 910
250 260 270 280
pF1KE1 ---PPRPPLP-ESLPPPPP----GGLPLPPMP-----PTGPAPSG--PPGPP------QL
:: :::: ..::::: : :::::.: : : :.. :: :: :
NP_001 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL
920 930 940 950 960 970
290 300 310 320
pF1KE1 PPPAPG--VHPPAPVVHPPASGVHPPAP----GVHPPAP----GVHPPAP----GVHPPT
::: :: . :: :. :..:. :: : :. :: : :. :: : :. ::
NP_001 PPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP
980 990 1000 1010 1020
330 340 350 360
pF1KE1 ----SGVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----GVHPPAP----
.:. :: : :. :: : :. :: : :. :: : :. :: :
NP_001 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA
1030 1040 1050 1060 1070 1080
370 380 390 400
pF1KE1 GVHPPP---SAGVHPQAP--GVHPAAPAVHPQAPGVHPPAP----GMHPQAP----GVHP
:. ::: .::. : : :: : : : :. :: : :. : : :. :
NP_001 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPP
1090 1100 1110 1120 1130 1140
410 420 430 440 450
pF1KE1 QPP----GVHPSAP----GVHPQPP----GVHPSNP----GVHPPTPMPPM-LRPPLPSE
:: :. : : :. : :: :. : : :. :: :.: . . :: :
NP_001 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP
1150 1160 1170 1180 1190 1200
460
pF1KE1 GPGNIPPPPPTN
: : ::::::
NP_001 GAG-IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG
1210 1220 1230 1240 1250 1260
>>NP_005030 (OMIM: 180989) basic salivary proline-rich p (331 aa)
initn: 532 init1: 321 opt: 518 Z-score: 194.4 bits: 44.8 E(85289): 0.00043
Smith-Waterman score: 532; 37.8% identity (52.0% similar) in 275 aa overlap (213-462:46-298)
190 200 210 220 230
pF1KE1 VPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPP--GVKRP--PPPLM
: . :: ::. : ::: : ..: :::
NP_005 AQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP--
20 30 40 50 60 70
240 250 260 270 280 290
pF1KE1 NGLPPRPPLPE---SLPPPPPGGLPLPPMPPTGPAPSGPPGPP---QLPPPAPGVHPPAP
: : :: :. : : : : : : : : :.::: :: : ::: : .: .:
NP_005 PGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP
80 90 100 110 120 130
300 310 320 330 340 350
pF1KE1 VVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHP
::.. :: : . .: : : :: .: .: .: :: :: .: .: :
NP_005 --PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---PPPPG-KPQGP---P
140 150 160 170 180
360 370 380 390 400
pF1KE1 PAPGVHPPAPGVHPPPSA--GVHPQAPGVHPA-APAVHPQAPGVHPPAPGMHPQAPGVHP
: : .: .: :::. : ::. . . .: .::.: :: : .::.: :
NP_005 PQGGKKPQGP---PPPGKPQGPPPQGDKSRSSQSPPGKPQGP---PPQGGNQPQGP---P
190 200 210 220 230
410 420 430 440 450
pF1KE1 QPPGVHPSAP----GVHPQ--PPGVHPSNPGVHPPTPMPPMLRPPLPSEGP----GNIP-
::: .:..: : .:: :: .:..: .. . :: .:: :: :
NP_005 PPPG-KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ
240 250 260 270 280 290
460
pF1KE1 -PPPPTN
::::
NP_005 GPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ
300 310 320 330
464 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:26:12 2016 done: Mon Nov 7 02:26:13 2016
Total Scan time: 9.930 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]