Result of FASTA (omim) for
pFN21AE1508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1508, 142 aa
1>>>pF1KE1508 142 - 142 aa - 142 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3427+/-0.00037; mu= 10.6498+/- 0.023
mean_var=54.3260+/-10.701, 0's: 0 Z-trim(112.8): 21 B-trim: 989 in 2/52
Lambda= 0.174009
statistics sampled from 21828 (21848) to 21828 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.256), width: 16
Scan time: 5.000
The best scores are: opt bits E(85289)
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 909 236.0 1.6e-62
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 909 236.0 1.6e-62
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 909 236.0 1.7e-62
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 563 149.1 2.2e-36
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 563 149.1 2.2e-36
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 485 129.5 1.7e-30
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 436 117.2 8.8e-27
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 362 98.7 3.6e-21
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 362 98.7 3.6e-21
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 357 97.4 8.5e-21
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 330 90.6 9.3e-19
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 321 88.4 4.5e-18
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 230 65.5 3.5e-11
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 230 65.5 3.5e-11
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 230 65.5 3.5e-11
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 230 65.5 3.5e-11
NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 186 54.5 9e-08
XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 186 54.5 9.6e-08
XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 183 53.7 1.1e-07
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 909 init1: 909 opt: 909 Z-score: 1243.5 bits: 236.0 E(85289): 1.6e-62
Smith-Waterman score: 909; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
70 80 90 100 110 120
130 140
pF1KE1 EAHAAWDKFLSVVSSVLTEKYR
::::::::::::::::::::::
XP_005 EAHAAWDKFLSVVSSVLTEKYR
130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 909 init1: 909 opt: 909 Z-score: 1243.5 bits: 236.0 E(85289): 1.6e-62
Smith-Waterman score: 909; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
70 80 90 100 110 120
130 140
pF1KE1 EAHAAWDKFLSVVSSVLTEKYR
::::::::::::::::::::::
NP_005 EAHAAWDKFLSVVSSVLTEKYR
130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 909 init1: 909 opt: 909 Z-score: 1242.9 bits: 236.0 E(85289): 1.7e-62
Smith-Waterman score: 909; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:13-154)
10 20 30 40
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFD
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLV
70 80 90 100 110 120
110 120 130 140
pF1KE1 TLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
::::::::::::::::::::::::::::::::::
XP_005 TLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
130 140 150
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 563 init1: 563 opt: 563 Z-score: 774.1 bits: 149.1 E(85289): 2.2e-36
Smith-Waterman score: 563; 59.9% identity (83.1% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
: :. ...: . . :.:....: :.:.:::.::: : :::::::::: ::::...::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
.::. :. .:: .::. .::: ::.:::. :::::::::::::::::::::..::.::
NP_000 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
70 80 90 100 110 120
130 140
pF1KE1 EAHAAWDKFLSVVSSVLTEKYR
.::. ::::. ::.::: :::
NP_000 AVHASLDKFLASVSTVLTSKYR
130 140
>>NP_000508 (OMIM: 140700,141850,604131,613978) hemoglob (142 aa)
initn: 563 init1: 563 opt: 563 Z-score: 774.1 bits: 149.1 E(85289): 2.2e-36
Smith-Waterman score: 563; 59.9% identity (83.1% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
: :. ...: . . :.:....: :.:.:::.::: : :::::::::: ::::...::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
.::. :. .:: .::. .::: ::.:::. :::::::::::::::::::::..::.::
NP_000 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
70 80 90 100 110 120
130 140
pF1KE1 EAHAAWDKFLSVVSSVLTEKYR
.::. ::::. ::.::: :::
NP_000 AVHASLDKFLASVSTVLTSKYR
130 140
>>NP_005322 (OMIM: 142240) hemoglobin subunit theta-1 [H (142 aa)
initn: 485 init1: 485 opt: 485 Z-score: 668.3 bits: 129.5 E(85289): 1.7e-30
Smith-Waterman score: 485; 52.1% identity (80.3% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
:.:. .:... ..: :..... . ::.::: ::. : ::::: :.:: :::.:.::::
NP_005 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
.::. :.. ::. .::. ::: ::.::: :::::..:.::.:::::::: ..:.::.
NP_005 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
70 80 90 100 110 120
130 140
pF1KE1 EAHAAWDKFLSVVSSVLTEKYR
.:. ::::: : :.:. .::
NP_005 ALQASLDKFLSHVISALVSEYR
130 140
>>NP_001003938 (OMIM: 609639) hemoglobin subunit mu [Hom (141 aa)
initn: 436 init1: 436 opt: 436 Z-score: 601.8 bits: 117.2 E(85289): 8.8e-27
Smith-Waterman score: 436; 47.9% identity (77.9% similar) in 140 aa overlap (3-142:2-141)
10 20 30 40 50 60
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
:. ::. :...: :. . .:.: : ::: .:.::.::::.. ..:: .::
NP_001 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLLSHG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
....:::: ::. .:.. .::: :..::: .:::::.:: :: .:. :.::... .::.
NP_001 QRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASHLQDEFTV
60 70 80 90 100 110
130 140
pF1KE1 EAHAAWDKFLSVVSSVLTEKYR
. .:::::::. :. :::::::
NP_001 QMQAAWDKFLTGVAVVLTEKYR
120 130 140
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 324 init1: 272 opt: 362 Z-score: 501.1 bits: 98.7 E(85289): 3.6e-21
Smith-Waterman score: 362; 40.0% identity (77.2% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLHPGSA----
.:. ... :.:.:.:.... : ::: ::.. .: :. .: : .: .::
NP_000 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 -QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
...:::.::....:::.: .::. :....::::: :.::: :::::.. :...:: .
NP_000 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
60 70 80 90 100 110
120 130 140
pF1KE1 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
: .:: :..:.:.:....:.:.:. .:
NP_000 FGKEFTPEVQASWQKMVTAVASALSSRYH
120 130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 324 init1: 272 opt: 362 Z-score: 501.1 bits: 98.7 E(85289): 3.6e-21
Smith-Waterman score: 362; 40.0% identity (76.6% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLHPGSA----
.:. ... :.:.:.:.... : ::: ::.. .: :. .: : .: .::
NP_000 MGHFTEEDKATITSLWGKVNVE--DAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 -QLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
...:::.::....:::.: .::. :....::::: :.::: :::::.. :...:: .
NP_000 PKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
60 70 80 90 100 110
120 130 140
pF1KE1 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
: .:: :..:.:.:... :.:.:. .:
NP_000 FGKEFTPEVQASWQKMVTGVASALSSRYH
120 130 140
>>NP_005321 (OMIM: 142100) hemoglobin subunit epsilon [H (147 aa)
initn: 287 init1: 287 opt: 357 Z-score: 494.4 bits: 97.4 E(85289): 8.5e-21
Smith-Waterman score: 357; 40.0% identity (75.9% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE1 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
.: :.. ..:.:.:.... : :.: ::.. .: :. .: : .: : :.
NP_005 MVHFTAEEKAAVTSLWSKMNVE--EAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
...:::.::... :::.:..:.. :..:::::: :.::: :::::.. ... ::..
NP_005 PKVKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATH
60 70 80 90 100 110
120 130 140
pF1KE1 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
: .:: :..:::.:..:.:. .:..::
NP_005 FGKEFTPEVQAAWQKLVSAVAIALAHKYH
120 130 140
142 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:35:22 2016 done: Sun Nov 6 22:35:23 2016
Total Scan time: 5.000 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]