Result of FASTA (omim) for
pFN21AE1492
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1492, 846 aa
1>>>pF1KE1492 846 - 846 aa - 846 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6754+/-0.000422; mu= 3.7236+/- 0.026
mean_var=150.6160+/-30.420, 0's: 0 Z-trim(115.2): 40 B-trim: 0 in 0/51
Lambda= 0.104505
statistics sampled from 25495 (25522) to 25495 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.299), width: 16
Scan time: 13.770
The best scores are: opt bits E(85289)
XP_006711903 (OMIM: 606063) PREDICTED: exonuclease ( 846) 5582 854.2 0
XP_011542623 (OMIM: 606063) PREDICTED: exonuclease ( 846) 5582 854.2 0
XP_011542624 (OMIM: 606063) PREDICTED: exonuclease ( 846) 5582 854.2 0
NP_569082 (OMIM: 606063) exonuclease 1 isoform b [ ( 846) 5582 854.2 0
NP_006018 (OMIM: 606063) exonuclease 1 isoform b [ ( 846) 5582 854.2 0
XP_011542625 (OMIM: 606063) PREDICTED: exonuclease ( 845) 5565 851.7 0
NP_001306153 (OMIM: 606063) exonuclease 1 isoform ( 845) 5565 851.7 0
NP_003677 (OMIM: 606063) exonuclease 1 isoform a [ ( 803) 5273 807.6 0
XP_016858282 (OMIM: 606063) PREDICTED: exonuclease ( 806) 4940 757.4 5.7e-218
XP_011542626 (OMIM: 606063) PREDICTED: exonuclease ( 806) 4940 757.4 5.7e-218
XP_011542627 (OMIM: 606063) PREDICTED: exonuclease ( 525) 3280 507.1 8.4e-143
NP_004102 (OMIM: 600393) flap endonuclease 1 [Homo ( 380) 371 68.5 6.7e-11
>>XP_006711903 (OMIM: 606063) PREDICTED: exonuclease 1 i (846 aa)
initn: 5582 init1: 5582 opt: 5582 Z-score: 4557.1 bits: 854.2 E(85289): 0
Smith-Waterman score: 5582; 99.8% identity (99.8% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
790 800 810 820 830 840
pF1KE1 QRAIFQ
::::::
XP_006 QRAIFQ
>>XP_011542623 (OMIM: 606063) PREDICTED: exonuclease 1 i (846 aa)
initn: 5582 init1: 5582 opt: 5582 Z-score: 4557.1 bits: 854.2 E(85289): 0
Smith-Waterman score: 5582; 99.8% identity (99.8% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
790 800 810 820 830 840
pF1KE1 QRAIFQ
::::::
XP_011 QRAIFQ
>>XP_011542624 (OMIM: 606063) PREDICTED: exonuclease 1 i (846 aa)
initn: 5582 init1: 5582 opt: 5582 Z-score: 4557.1 bits: 854.2 E(85289): 0
Smith-Waterman score: 5582; 99.8% identity (99.8% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
790 800 810 820 830 840
pF1KE1 QRAIFQ
::::::
XP_011 QRAIFQ
>>NP_569082 (OMIM: 606063) exonuclease 1 isoform b [Homo (846 aa)
initn: 5582 init1: 5582 opt: 5582 Z-score: 4557.1 bits: 854.2 E(85289): 0
Smith-Waterman score: 5582; 99.8% identity (99.8% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
790 800 810 820 830 840
pF1KE1 QRAIFQ
::::::
NP_569 QRAIFQ
>>NP_006018 (OMIM: 606063) exonuclease 1 isoform b [Homo (846 aa)
initn: 5582 init1: 5582 opt: 5582 Z-score: 4557.1 bits: 854.2 E(85289): 0
Smith-Waterman score: 5582; 99.8% identity (99.8% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
790 800 810 820 830 840
pF1KE1 QRAIFQ
::::::
NP_006 QRAIFQ
>>XP_011542625 (OMIM: 606063) PREDICTED: exonuclease 1 i (845 aa)
initn: 2844 init1: 2814 opt: 5565 Z-score: 4543.2 bits: 851.7 E(85289): 0
Smith-Waterman score: 5565; 99.6% identity (99.6% similar) in 846 aa overlap (1-846:1-845)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RS-ELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
780 790 800 810 820 830
pF1KE1 QRAIFQ
::::::
XP_011 QRAIFQ
840
>>NP_001306153 (OMIM: 606063) exonuclease 1 isoform c [H (845 aa)
initn: 2844 init1: 2814 opt: 5565 Z-score: 4543.2 bits: 851.7 E(85289): 0
Smith-Waterman score: 5565; 99.6% identity (99.6% similar) in 846 aa overlap (1-846:1-845)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RS-ELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
780 790 800 810 820 830
pF1KE1 QRAIFQ
::::::
NP_001 QRAIFQ
840
>>NP_003677 (OMIM: 606063) exonuclease 1 isoform a [Homo (803 aa)
initn: 5273 init1: 5273 opt: 5273 Z-score: 4305.7 bits: 807.6 E(85289): 0
Smith-Waterman score: 5273; 99.8% identity (99.8% similar) in 802 aa overlap (1-802:1-802)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::
NP_003 AENKPGLQIKLNELWKNFGFKKF
790 800
>>XP_016858282 (OMIM: 606063) PREDICTED: exonuclease 1 i (806 aa)
initn: 5294 init1: 4940 opt: 4940 Z-score: 4034.3 bits: 757.4 E(85289): 5.7e-218
Smith-Waterman score: 5218; 95.0% identity (95.0% similar) in 846 aa overlap (1-846:1-806)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDR------
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::
XP_016 ----------------------------------RRQANLLKGKQLLREGKVSEARECFT
60 70 80
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
750 760 770 780 790 800
pF1KE1 QRAIFQ
::::::
XP_016 QRAIFQ
>>XP_011542626 (OMIM: 606063) PREDICTED: exonuclease 1 i (806 aa)
initn: 5294 init1: 4940 opt: 4940 Z-score: 4034.3 bits: 757.4 E(85289): 5.7e-218
Smith-Waterman score: 5218; 95.0% identity (95.0% similar) in 846 aa overlap (1-846:1-806)
10 20 30 40 50 60
pF1KE1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDR------
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
::::::::::::::::::::::::::
XP_011 ----------------------------------RRQANLLKGKQLLREGKVSEARECFT
60 70 80
130 140 150 160 170 180
pF1KE1 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE1 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE1 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE1 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE1 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE1 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE1 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE1 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE1 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE1 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
750 760 770 780 790 800
pF1KE1 QRAIFQ
::::::
XP_011 QRAIFQ
846 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:13:09 2016 done: Mon Nov 7 02:13:11 2016
Total Scan time: 13.770 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]