Result of FASTA (omim) for
pFN21AE1484
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1484, 655 aa
1>>>pF1KE1484 655 - 655 aa - 655 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6062+/-0.000468; mu= -3.8205+/- 0.029
mean_var=390.4091+/-79.226, 0's: 0 Z-trim(120.7): 344 B-trim: 85 in 1/56
Lambda= 0.064910
statistics sampled from 35999 (36360) to 35999 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.426), width: 16
Scan time: 13.670
The best scores are: opt bits E(85289)
NP_006779 (OMIM: 605801) ralA-binding protein 1 [H ( 655) 4275 415.0 4.2e-115
NP_001243776 (OMIM: 600365) active breakpoint clus ( 310) 341 46.3 0.0002
NP_067585 (OMIM: 151410,608232,613065) breakpoint (1227) 351 47.8 0.00027
NP_004318 (OMIM: 151410,608232,613065) breakpoint (1271) 351 47.9 0.00028
NP_001269078 (OMIM: 600365) active breakpoint clus ( 641) 341 46.6 0.00033
NP_001309769 (OMIM: 600365) active breakpoint clus ( 813) 341 46.7 0.00039
NP_001153218 (OMIM: 600365) active breakpoint clus ( 813) 341 46.7 0.00039
NP_001083 (OMIM: 600365) active breakpoint cluster ( 822) 341 46.7 0.00039
NP_068781 (OMIM: 600365) active breakpoint cluster ( 859) 341 46.7 0.00041
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397) 332 45.6 0.00043
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432) 332 45.6 0.00045
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 332 45.6 0.00049
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 332 45.6 0.00049
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 332 45.6 0.00049
NP_001309770 (OMIM: 600365) active breakpoint clus (1118) 341 46.9 0.00049
NP_112595 (OMIM: 610586) rho GTPase-activating pro ( 655) 325 45.1 0.00095
NP_859071 (OMIM: 614264) rho GTPase-activating pro ( 890) 327 45.5 0.001
XP_016872443 (OMIM: 610577) PREDICTED: rho GTPase- ( 742) 325 45.2 0.001
NP_001257627 (OMIM: 610577) rho GTPase-activating ( 769) 325 45.2 0.0011
XP_011518063 (OMIM: 610577) PREDICTED: rho GTPase- ( 772) 325 45.2 0.0011
NP_001257628 (OMIM: 610577) rho GTPase-activating ( 794) 325 45.2 0.0011
XP_005252701 (OMIM: 610577) PREDICTED: rho GTPase- ( 794) 325 45.2 0.0011
NP_001257626 (OMIM: 610577) rho GTPase-activating ( 799) 325 45.2 0.0011
XP_016856449 (OMIM: 614264) PREDICTED: rho GTPase- ( 967) 327 45.5 0.0011
NP_001257625 (OMIM: 610577) rho GTPase-activating ( 816) 325 45.2 0.0011
NP_001257624 (OMIM: 610577) rho GTPase-activating ( 841) 325 45.2 0.0011
NP_060757 (OMIM: 610577) rho GTPase-activating pro ( 846) 325 45.2 0.0011
XP_005245127 (OMIM: 614264) PREDICTED: rho GTPase- (1044) 327 45.5 0.0012
NP_001020769 (OMIM: 614264) rho GTPase-activating (1101) 327 45.5 0.0012
XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase- ( 653) 321 44.7 0.0012
NP_001036134 (OMIM: 610586) rho GTPase-activating ( 653) 321 44.7 0.0012
NP_001274734 (OMIM: 610586) rho GTPase-activating ( 663) 321 44.8 0.0012
NP_001020787 (OMIM: 610586) rho GTPase-activating ( 748) 321 44.8 0.0014
XP_016882203 (OMIM: 605277) PREDICTED: rho GTPase- (1499) 325 45.5 0.0017
NP_004482 (OMIM: 605277) rho GTPase-activating pro (1499) 325 45.5 0.0017
XP_011519925 (OMIM: 604875) PREDICTED: unconventio (1737) 325 45.6 0.0019
XP_016877719 (OMIM: 604875) PREDICTED: unconventio (2547) 325 45.7 0.0024
XP_011519924 (OMIM: 604875) PREDICTED: unconventio (2566) 325 45.7 0.0024
XP_016877718 (OMIM: 604875) PREDICTED: unconventio (2566) 325 45.7 0.0024
XP_011519923 (OMIM: 604875) PREDICTED: unconventio (2598) 325 45.7 0.0025
XP_011519922 (OMIM: 604875) PREDICTED: unconventio (2618) 325 45.7 0.0025
XP_011519921 (OMIM: 604875) PREDICTED: unconventio (2619) 325 45.7 0.0025
XP_016877717 (OMIM: 604875) PREDICTED: unconventio (2619) 325 45.7 0.0025
XP_011519919 (OMIM: 604875) PREDICTED: unconventio (2637) 325 45.8 0.0025
XP_011519917 (OMIM: 604875) PREDICTED: unconventio (2638) 325 45.8 0.0025
XP_011519918 (OMIM: 604875) PREDICTED: unconventio (2638) 325 45.8 0.0025
XP_011519916 (OMIM: 604875) PREDICTED: unconventio (2638) 325 45.8 0.0025
XP_011519915 (OMIM: 604875) PREDICTED: unconventio (2638) 325 45.8 0.0025
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 300 42.4 0.0026
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 300 42.4 0.0027
>>NP_006779 (OMIM: 605801) ralA-binding protein 1 [Homo (655 aa)
initn: 4275 init1: 4275 opt: 4275 Z-score: 2187.4 bits: 415.0 E(85289): 4.2e-115
Smith-Waterman score: 4275; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE1 MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK
550 560 570 580 590 600
610 620 630 640 650
pF1KE1 AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI
610 620 630 640 650
>>NP_001243776 (OMIM: 600365) active breakpoint cluster (310 aa)
initn: 267 init1: 180 opt: 341 Z-score: 200.4 bits: 46.3 E(85289): 0.0002
Smith-Waterman score: 341; 31.2% identity (68.2% similar) in 192 aa overlap (189-376:95-282)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .. ...: . ..: . :.:..
NP_001 EMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKR----ERSKVPYIVRQCVE
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST---NLEDYEPNTVASLLKQYLRDLP
::: :.. ::::.::. . .. :::..: ... : :.. :..:. :: :.:.::
NP_001 EVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELP
130 140 150 160 170 180
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: ::: .:.: : :. . . . : . ...::. ::. : . . .:. :. .: :: .
NP_001 EPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPIN
190 200 210 220 230 240
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLY-VFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPET
::...:.. :..::. ..: . .: . ..... :. ::
NP_001 KMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELK
250 260 270 280 290 300
400 410 420 430 440 450
pF1KE1 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK
NP_001 RNTLYFSTDV
310
>>NP_067585 (OMIM: 151410,608232,613065) breakpoint clus (1227 aa)
initn: 318 init1: 183 opt: 351 Z-score: 198.0 bits: 47.8 E(85289): 0.00027
Smith-Waterman score: 351; 34.5% identity (68.5% similar) in 165 aa overlap (189-350:1007-1167)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .: ...: . ..: . :.:..
NP_067 AMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKR----ERSKVPYIVRQCVE
980 990 1000 1010 1020 1030
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYD---REESTNLEDYEPNTVASLLKQYLRDLP
.:. ::. :::::::. . .. ::::.: .. :. . ... :..:. :: :.:.::
NP_067 EIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELP
1040 1050 1060 1070 1080 1090
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: :.: :..: : :. . . . : . . :: ::: : : . .:. :. .: :: .
NP_067 EPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVN
1100 1110 1120 1130 1140 1150
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQ
::...:.. :..::.
NP_067 KMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIP
1160 1170 1180 1190 1200 1210
>>NP_004318 (OMIM: 151410,608232,613065) breakpoint clus (1271 aa)
initn: 318 init1: 183 opt: 351 Z-score: 197.9 bits: 47.9 E(85289): 0.00028
Smith-Waterman score: 351; 34.5% identity (68.5% similar) in 165 aa overlap (189-350:1051-1211)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .: ...: . ..: . :.:..
NP_004 AMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKR----ERSKVPYIVRQCVE
1030 1040 1050 1060 1070
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYD---REESTNLEDYEPNTVASLLKQYLRDLP
.:. ::. :::::::. . .. ::::.: .. :. . ... :..:. :: :.:.::
NP_004 EIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELP
1080 1090 1100 1110 1120 1130
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: :.: :..: : :. . . . : . . :: ::: : : . .:. :. .: :: .
NP_004 EPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVN
1140 1150 1160 1170 1180 1190
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQ
::...:.. :..::.
NP_004 KMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIP
1200 1210 1220 1230 1240 1250
>>NP_001269078 (OMIM: 600365) active breakpoint cluster (641 aa)
initn: 267 init1: 180 opt: 341 Z-score: 196.5 bits: 46.6 E(85289): 0.00033
Smith-Waterman score: 341; 31.2% identity (68.2% similar) in 192 aa overlap (189-376:426-613)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .. ...: . ..: . :.:..
NP_001 EMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKR----ERSKVPYIVRQCVE
400 410 420 430 440 450
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST---NLEDYEPNTVASLLKQYLRDLP
::: :.. ::::.::. . .. :::..: ... : :.. :..:. :: :.:.::
NP_001 EVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELP
460 470 480 490 500 510
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: ::: .:.: : :. . . . : . ...::. ::. : . . .:. :. .: :: .
NP_001 EPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPIN
520 530 540 550 560 570
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLY-VFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPET
::...:.. :..::. ..: . .: . ..... :. ::
NP_001 KMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELK
580 590 600 610 620 630
400 410 420 430 440 450
pF1KE1 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK
NP_001 RNTLYFSTDV
640
>>NP_001309769 (OMIM: 600365) active breakpoint cluster (813 aa)
initn: 267 init1: 180 opt: 341 Z-score: 195.2 bits: 46.7 E(85289): 0.00039
Smith-Waterman score: 341; 31.2% identity (68.2% similar) in 192 aa overlap (189-376:598-785)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .. ...: . ..: . :.:..
NP_001 EMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKR----ERSKVPYIVRQCVE
570 580 590 600 610 620
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST---NLEDYEPNTVASLLKQYLRDLP
::: :.. ::::.::. . .. :::..: ... : :.. :..:. :: :.:.::
NP_001 EVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELP
630 640 650 660 670 680
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: ::: .:.: : :. . . . : . ...::. ::. : . . .:. :. .: :: .
NP_001 EPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPIN
690 700 710 720 730 740
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLY-VFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPET
::...:.. :..::. ..: . .: . ..... :. ::
NP_001 KMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELK
750 760 770 780 790 800
400 410 420 430 440 450
pF1KE1 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK
NP_001 RNTLYFSTDV
810
>>NP_001153218 (OMIM: 600365) active breakpoint cluster (813 aa)
initn: 267 init1: 180 opt: 341 Z-score: 195.2 bits: 46.7 E(85289): 0.00039
Smith-Waterman score: 341; 31.2% identity (68.2% similar) in 192 aa overlap (189-376:598-785)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .. ...: . ..: . :.:..
NP_001 EMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKR----ERSKVPYIVRQCVE
570 580 590 600 610 620
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST---NLEDYEPNTVASLLKQYLRDLP
::: :.. ::::.::. . .. :::..: ... : :.. :..:. :: :.:.::
NP_001 EVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELP
630 640 650 660 670 680
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: ::: .:.: : :. . . . : . ...::. ::. : . . .:. :. .: :: .
NP_001 EPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPIN
690 700 710 720 730 740
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLY-VFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPET
::...:.. :..::. ..: . .: . ..... :. ::
NP_001 KMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELK
750 760 770 780 790 800
400 410 420 430 440 450
pF1KE1 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK
NP_001 RNTLYFSTDV
810
>>NP_001083 (OMIM: 600365) active breakpoint cluster reg (822 aa)
initn: 267 init1: 180 opt: 341 Z-score: 195.1 bits: 46.7 E(85289): 0.00039
Smith-Waterman score: 341; 31.2% identity (68.2% similar) in 192 aa overlap (189-376:607-794)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .. ...: . ..: . :.:..
NP_001 EMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKR----ERSKVPYIVRQCVE
580 590 600 610 620 630
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST---NLEDYEPNTVASLLKQYLRDLP
::: :.. ::::.::. . .. :::..: ... : :.. :..:. :: :.:.::
NP_001 EVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELP
640 650 660 670 680 690
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: ::: .:.: : :. . . . : . ...::. ::. : . . .:. :. .: :: .
NP_001 EPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPIN
700 710 720 730 740 750
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLY-VFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPET
::...:.. :..::. ..: . .: . ..... :. ::
NP_001 KMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELK
760 770 780 790 800 810
400 410 420 430 440 450
pF1KE1 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK
NP_001 RNTLYFSTDV
820
>>NP_068781 (OMIM: 600365) active breakpoint cluster reg (859 aa)
initn: 267 init1: 180 opt: 341 Z-score: 194.9 bits: 46.7 E(85289): 0.00041
Smith-Waterman score: 341; 31.2% identity (68.2% similar) in 192 aa overlap (189-376:644-831)
160 170 180 190 200 210
pF1KE1 VVKQWKEKKKKKKPIQEPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECID
.::. .. ...: . ..: . :.:..
NP_068 EMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKR----ERSKVPYIVRQCVE
620 630 640 650 660
220 230 240 250 260 270
pF1KE1 YVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST---NLEDYEPNTVASLLKQYLRDLP
::: :.. ::::.::. . .. :::..: ... : :.. :..:. :: :.:.::
NP_068 EVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELP
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE1 ENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELET
: ::: .:.: : :. . . . : . ...::. ::. : . . .:. :. .: :: .
NP_068 EPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPIN
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE1 KMNIQNISIVLSPTVQISNRVLY-VFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPET
::...:.. :..::. ..: . .: . ..... :. ::
NP_068 KMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELK
790 800 810 820 830 840
400 410 420 430 440 450
pF1KE1 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK
NP_068 RNTLYFSTDV
850
>>XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase-acti (397 aa)
initn: 276 init1: 156 opt: 332 Z-score: 194.5 bits: 45.6 E(85289): 0.00043
Smith-Waterman score: 332; 28.8% identity (62.8% similar) in 250 aa overlap (113-350:115-360)
90 100 110 120 130 140
pF1KE1 EGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKKKEKDFKIKEKPKEE--KHKEEK
: : ... . :::... . : .: .
XP_011 SGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCPSRNLELFKIQRSSSTELLSHYDSD
90 100 110 120 130 140
150 160 170 180 190
pF1KE1 HKEEKHKEKKSKDL----TAADVVKQWKEKKKKKKPI-QEPEVPQIDVPNL--KPIFGIP
::.: ...:: . .:.:. . . :.. :: : ..: . .. .: :::
XP_011 IKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSH
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE1 LADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDREEST
: . :: .. .: ..::. ::: :. .::::::: . ...:. ..::.
XP_011 LHKVCER----ENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKL
210 220 230 240 250 260
260 270 280 290 300 310
pF1KE1 NLED--YEP-NTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLKEL
::.: .: ..:.. ::...:.::: :. .. .: :: . .. ... . :...:
XP_011 NLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKL
270 280 290 300 310 320
320 330 340 350 360 370
pF1KE1 PECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGN
: : .. :. :. ...:: .. :. :...::..::.
XP_011 PPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQI
330 340 350 360 370 380
380 390 400 410 420 430
pF1KE1 VVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLW
XP_011 AELMLSEYSKIFGSEED
390
655 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:36:01 2016 done: Mon Nov 7 01:36:03 2016
Total Scan time: 13.670 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]