Result of FASTA (omim) for
pFN21AE1476
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1476, 655 aa
1>>>pF1KE1476 655 - 655 aa - 655 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8848+/-0.000349; mu= 8.0292+/- 0.022
mean_var=152.4848+/-30.696, 0's: 0 Z-trim(118.6): 62 B-trim: 525 in 2/57
Lambda= 0.103863
statistics sampled from 31602 (31664) to 31602 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.371), width: 16
Scan time: 12.730
The best scores are: opt bits E(85289)
NP_055267 (OMIM: 605732) tumor necrosis factor rec ( 655) 4427 675.5 1.7e-193
XP_016866233 (OMIM: 605732) PREDICTED: tumor necro ( 444) 2859 440.4 6.6e-123
NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 417 74.5 8.6e-13
NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 412 73.6 1.1e-12
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 414 74.0 1.3e-12
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 414 74.0 1.3e-12
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 414 74.1 1.3e-12
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 414 74.1 1.3e-12
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 414 74.1 1.4e-12
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 414 74.1 1.4e-12
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 344 63.5 1.7e-09
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 337 62.4 2.4e-09
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 337 62.5 3.7e-09
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 332 61.7 6e-09
XP_006710681 (OMIM: 602250) PREDICTED: tumor necro ( 239) 319 59.6 1.5e-08
XP_011539688 (OMIM: 602250) PREDICTED: tumor necro ( 255) 319 59.7 1.6e-08
NP_001552 (OMIM: 602250) tumor necrosis factor rec ( 255) 319 59.7 1.6e-08
NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 305 57.5 6.3e-08
XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 305 57.6 8.1e-08
NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 295 56.1 1.9e-07
NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 295 56.1 2.4e-07
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 290 55.3 3.5e-07
NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 289 55.2 3.8e-07
NP_003830 (OMIM: 174810,602080,603499,612301) tumo ( 616) 295 56.3 3.9e-07
NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 286 54.8 5.5e-07
XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 281 53.9 7.2e-07
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 279 53.6 8.1e-07
NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 281 54.0 8.7e-07
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 277 53.3 9.4e-07
XP_011524546 (OMIM: 174810,602080,603499,612301) P ( 621) 282 54.4 1.5e-06
XP_016881554 (OMIM: 174810,602080,603499,612301) P ( 566) 233 47.0 0.00023
NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 202 42.1 0.0025
NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259) 203 42.3 0.0027
XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 202 42.2 0.0033
>>NP_055267 (OMIM: 605732) tumor necrosis factor recepto (655 aa)
initn: 4427 init1: 4427 opt: 4427 Z-score: 3594.9 bits: 675.5 E(85289): 1.7e-193
Smith-Waterman score: 4427; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
550 560 570 580 590 600
610 620 630 640 650
pF1KE1 DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
610 620 630 640 650
>>XP_016866233 (OMIM: 605732) PREDICTED: tumor necrosis (444 aa)
initn: 2859 init1: 2859 opt: 2859 Z-score: 2327.6 bits: 440.4 E(85289): 6.6e-123
Smith-Waterman score: 2859; 100.0% identity (100.0% similar) in 415 aa overlap (1-415:1-415)
10 20 30 40 50 60
pF1KE1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGPHDEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
XP_016 WGLMERHIQDIYIQRSNQDSERWG
430 440
>>NP_002537 (OMIM: 239000,602643) tumor necrosis factor (401 aa)
initn: 475 init1: 378 opt: 417 Z-score: 350.6 bits: 74.5 E(85289): 8.6e-13
Smith-Waterman score: 417; 28.5% identity (50.0% similar) in 288 aa overlap (54-334:28-308)
30 40 50 60 70 80
pF1KE1 TMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNT
: : :. :.. : ::::: :::...:::
NP_002 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAK
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 SLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNAT
::. :: .: . ..: :: : . : : .: : : : .
NP_002 WKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEF
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE1 CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPG
: : :: :.:: . :: ... ::.: : ::. :: :. .:.: .:.. . :
NP_002 CLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKG
120 130 140 150 160 170
210 220 230 240 250
pF1KE1 TKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMN-------STES
. ::.: : .: .. . : . : . ::.. ..:. .. .:.
NP_002 NATHDNIC----SGNSESTQKCGIDVTLCEEAFFRFAVPTK-FTPNWLSVLVDNLPGTKV
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 NSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSM
:. . : : : :: : . ..: . . .: .. .. .::: . ..
NP_002 NAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTF
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE1 EATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVLVVIVVCSIRKSSRT
: . : : : : :
NP_002 EQLRSLMESLP--GKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALK
300 310 320 330 340 350
>>NP_003814 (OMIM: 603361) tumor necrosis factor recepto (300 aa)
initn: 408 init1: 408 opt: 412 Z-score: 348.4 bits: 73.6 E(85289): 1.1e-12
Smith-Waterman score: 412; 33.2% identity (54.3% similar) in 199 aa overlap (29-226:10-207)
10 20 30 40 50
pF1KE1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGF-LSTTTAQPEQKASNLIGTYRHVDR
::: : . : . : .. :: :
NP_003 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDA
10 20 30 40
60 70 80 90 100 110
pF1KE1 ATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIE
::. :.: .:: ::.:.. : : .:. :: .:. : .:.:. :. : :
NP_003 ETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 KLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDV
: : .: : : :.: . : :. :: : :: :: .....:. : ::::
NP_003 ARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 PSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETH
:: .:. . .: . .:.. ::.. :..: . .: :: ::
NP_003 SSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTR-VPGAEECERAVIDFVA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 EVPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVN
NP_003 FQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQAL
230 240 250 260 270 280
>>XP_016857701 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa)
initn: 421 init1: 187 opt: 414 Z-score: 347.6 bits: 74.0 E(85289): 1.3e-12
Smith-Waterman score: 414; 35.8% identity (59.1% similar) in 193 aa overlap (65-248:1-186)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
10 20 30
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
100 110 120 130 140
210 220 230 240 250 260
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP---EHMETHEVPSSTYVPKGMNSTESNSSASVRPK
:: : : . : .::.. .:.: . ..:. .: . .:
XP_016 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE1 VLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSMEATGGEKSS
XP_016 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVVSVSTALSPSSPGL
210 220 230 240 250 260
>>XP_016857702 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa)
initn: 421 init1: 187 opt: 414 Z-score: 347.6 bits: 74.0 E(85289): 1.3e-12
Smith-Waterman score: 414; 35.8% identity (59.1% similar) in 193 aa overlap (65-248:1-186)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
10 20 30
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
100 110 120 130 140
210 220 230 240 250 260
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP---EHMETHEVPSSTYVPKGMNSTESNSSASVRPK
:: : : . : .::.. .:.: . ..:. .: . .:
XP_016 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE1 VLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSMEATGGEKSS
XP_016 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVVSVSTALSPSSPGL
210 220 230 240 250 260
>>NP_001057 (OMIM: 191191) tumor necrosis factor recepto (461 aa)
initn: 429 init1: 187 opt: 414 Z-score: 347.3 bits: 74.1 E(85289): 1.3e-12
Smith-Waterman score: 445; 30.2% identity (55.4% similar) in 305 aa overlap (65-337:52-349)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
NP_001 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
30 40 50 60 70 80
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
NP_001 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
NP_001 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
150 160 170 180 190
210 220 230 240 250
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP-----EHM----ETHEVPSSTYV-PKGMNSTESNS
:: : : . : .::.. .:.: .: : .::.... : : . .:
NP_001 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 SAS--------VRPKVLSSIQEGTVPDNTSSARGKEDV----NKTLPNLQV--VNHQQGP
... : .:. . :.: . :. . . .:.: . . :::
NP_001 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGP
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 HHRHILKLLPSMEATGGEKSSTPI--KGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVL
...:.: :: ... :.:.. . ..: :..:.
NP_001 EQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGG
320 330 340 350 360 370
370 380 390 400 410 420
pF1KE1 VVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILKLV
NP_001 HGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQL
380 390 400 410 420 430
>>XP_011540365 (OMIM: 191191) PREDICTED: tumor necrosis (462 aa)
initn: 429 init1: 187 opt: 414 Z-score: 347.3 bits: 74.1 E(85289): 1.3e-12
Smith-Waterman score: 445; 30.2% identity (55.4% similar) in 305 aa overlap (65-337:52-349)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
XP_011 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
30 40 50 60 70 80
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
XP_011 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
XP_011 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
150 160 170 180 190
210 220 230 240 250
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP-----EHM----ETHEVPSSTYV-PKGMNSTESNS
:: : : . : .::.. .:.: .: : .::.... : : . .:
XP_011 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 SAS--------VRPKVLSSIQEGTVPDNTSSARGKEDV----NKTLPNLQV--VNHQQGP
... : .:. . :.: . :. . . .:.: . . :::
XP_011 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGP
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 HHRHILKLLPSMEATGGEKSSTPI--KGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVL
...:.: :: ... :.:.. . ..: :..:.
XP_011 EQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSADSSPG
320 330 340 350 360 370
370 380 390 400 410 420
pF1KE1 VVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILKLV
XP_011 GHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQ
380 390 400 410 420 430
>>XP_011540362 (OMIM: 191191) PREDICTED: tumor necrosis (484 aa)
initn: 429 init1: 187 opt: 414 Z-score: 347.0 bits: 74.1 E(85289): 1.4e-12
Smith-Waterman score: 445; 30.2% identity (55.4% similar) in 305 aa overlap (65-337:52-349)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
XP_011 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
30 40 50 60 70 80
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
XP_011 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
XP_011 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
150 160 170 180 190
210 220 230 240 250
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP-----EHM----ETHEVPSSTYV-PKGMNSTESNS
:: : : . : .::.. .:.: .: : .::.... : : . .:
XP_011 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 SAS--------VRPKVLSSIQEGTVPDNTSSARGKEDV----NKTLPNLQV--VNHQQGP
... : .:. . :.: . :. . . .:.: . . :::
XP_011 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGP
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 HHRHILKLLPSMEATGGEKSSTPI--KGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVL
...:.: :: ... :.:.. . ..: :..:.
XP_011 EQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSGLSDCM
320 330 340 350 360 370
370 380 390 400 410 420
pF1KE1 VVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILKLV
XP_011 YRHCLLLSPTPGCGTPADSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSS
380 390 400 410 420 430
>>XP_016857700 (OMIM: 191191) PREDICTED: tumor necrosis (491 aa)
initn: 421 init1: 187 opt: 414 Z-score: 346.9 bits: 74.1 E(85289): 1.4e-12
Smith-Waterman score: 414; 35.8% identity (59.1% similar) in 193 aa overlap (65-248:52-237)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
XP_016 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
30 40 50 60 70 80
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
150 160 170 180 190
210 220 230 240 250 260
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP---EHMETHEVPSSTYVPKGMNSTESNSSASVRPK
:: : : . : .::.. .:.: . ..:. .: . .:
XP_016 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
200 210 220 230 240 250
270 280 290 300 310 320
pF1KE1 VLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSMEATGGEKSS
XP_016 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVVSVSTALSPSSPGL
260 270 280 290 300 310
655 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:59:48 2016 done: Mon Nov 7 00:59:49 2016
Total Scan time: 12.730 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]