Result of FASTA (ccds) for
pFN21AE1476
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1476, 655 aa
1>>>pF1KE1476 655 - 655 aa - 655 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1774+/-0.000919; mu= 12.1733+/- 0.056
mean_var=141.5507+/-28.223, 0's: 0 Z-trim(110.7): 32 B-trim: 59 in 2/48
Lambda= 0.107800
statistics sampled from 11793 (11822) to 11793 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.363), width: 16
Scan time: 4.150
The best scores are: opt bits E(32554)
CCDS4921.1 TNFRSF21 gene_id:27242|Hs108|chr6 ( 655) 4427 700.4 2.1e-201
CCDS6326.1 TNFRSF11B gene_id:4982|Hs108|chr8 ( 401) 417 76.6 7.6e-14
CCDS13532.1 TNFRSF6B gene_id:8771|Hs108|chr20 ( 300) 412 75.7 1e-13
CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 ( 461) 414 76.1 1.2e-13
>>CCDS4921.1 TNFRSF21 gene_id:27242|Hs108|chr6 (655 aa)
initn: 4427 init1: 4427 opt: 4427 Z-score: 3729.5 bits: 700.4 E(32554): 2.1e-201
Smith-Waterman score: 4427; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
550 560 570 580 590 600
610 620 630 640 650
pF1KE1 DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
610 620 630 640 650
>>CCDS6326.1 TNFRSF11B gene_id:4982|Hs108|chr8 (401 aa)
initn: 475 init1: 378 opt: 417 Z-score: 362.0 bits: 76.6 E(32554): 7.6e-14
Smith-Waterman score: 417; 28.5% identity (50.0% similar) in 288 aa overlap (54-334:28-308)
30 40 50 60 70 80
pF1KE1 TMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNT
: : :. :.. : ::::: :::...:::
CCDS63 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAK
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 SLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNAT
::. :: .: . ..: :: : . : : .: : : : .
CCDS63 WKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEF
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE1 CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPG
: : :: :.:: . :: ... ::.: : ::. :: :. .:.: .:.. . :
CCDS63 CLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKG
120 130 140 150 160 170
210 220 230 240 250
pF1KE1 TKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMN-------STES
. ::.: : .: .. . : . : . ::.. ..:. .. .:.
CCDS63 NATHDNIC----SGNSESTQKCGIDVTLCEEAFFRFAVPTK-FTPNWLSVLVDNLPGTKV
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 NSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSM
:. . : : : :: : . ..: . . .: .. .. .::: . ..
CCDS63 NAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTF
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE1 EATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVLVVIVVCSIRKSSRT
: . : : : : :
CCDS63 EQLRSLMESLP--GKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALK
300 310 320 330 340 350
>>CCDS13532.1 TNFRSF6B gene_id:8771|Hs108|chr20 (300 aa)
initn: 408 init1: 408 opt: 412 Z-score: 359.5 bits: 75.7 E(32554): 1e-13
Smith-Waterman score: 412; 33.2% identity (54.3% similar) in 199 aa overlap (29-226:10-207)
10 20 30 40 50
pF1KE1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGF-LSTTTAQPEQKASNLIGTYRHVDR
::: : . : . : .. :: :
CCDS13 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDA
10 20 30 40
60 70 80 90 100 110
pF1KE1 ATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIE
::. :.: .:: ::.:.. : : .:. :: .:. : .:.:. :. : :
CCDS13 ETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 KLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDV
: : .: : : :.: . : :. :: : :: :: .....:. : ::::
CCDS13 ARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 PSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETH
:: .:. . .: . .:.. ::.. :..: . .: :: ::
CCDS13 SSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTR-VPGAEECERAVIDFVA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 EVPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVN
CCDS13 FQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQAL
230 240 250 260 270 280
>>CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 (461 aa)
initn: 429 init1: 187 opt: 414 Z-score: 358.6 bits: 76.1 E(32554): 1.2e-13
Smith-Waterman score: 445; 30.2% identity (55.4% similar) in 305 aa overlap (65-337:52-349)
40 50 60 70 80 90
pF1KE1 FLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVG
. :.:: : ... ::.:: ::.:: .
CCDS14 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
30 40 50 60 70 80
100 110 120 130 140
pF1KE1 TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHT
:.:. : . .: .:.. : ..: :. .: ::: :: . .. :::
CCDS14 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE1 VCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETD
: :.:: . :::: :: :: :: ::::.. ::. :. . : :.:.: ::. :
CCDS14 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQIC---NVVAI-PGNASMD
150 160 170 180 190
210 220 230 240 250
pF1KE1 NVCGTLPSFSSSTSPSPGTAIFPRP-----EHM----ETHEVPSSTYV-PKGMNSTESNS
:: : : . : .::.. .:.: .: : .::.... : : . .:
CCDS14 AVC---TSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 SAS--------VRPKVLSSIQEGTVPDNTSSARGKEDV----NKTLPNLQV--VNHQQGP
... : .:. . :.: . :. . . .:.: . . :::
CCDS14 TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGP
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 HHRHILKLLPSMEATGGEKSSTPI--KGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVL
...:.: :: ... :.:.. . ..: :..:.
CCDS14 EQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGG
320 330 340 350 360 370
370 380 390 400 410 420
pF1KE1 VVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILKLV
CCDS14 HGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQL
380 390 400 410 420 430
655 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:59:47 2016 done: Mon Nov 7 00:59:47 2016
Total Scan time: 4.150 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]