Result of FASTA (omim) for
pFN21AE1470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1470, 181 aa
1>>>pF1KE1470 181 - 181 aa - 181 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0597+/-0.000348; mu= 13.6246+/- 0.022
mean_var=58.6962+/-11.460, 0's: 0 Z-trim(112.9): 85 B-trim: 0 in 0/49
Lambda= 0.167405
statistics sampled from 21845 (21938) to 21845 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.257), width: 16
Scan time: 5.450
The best scores are: opt bits E(85289)
NP_004104 (OMIM: 601513,617166) fibroblast growth ( 181) 1195 296.8 1.3e-80
XP_005247284 (OMIM: 601513,617166) PREDICTED: fibr ( 207) 1171 291.0 8.1e-79
NP_066360 (OMIM: 601513,617166) fibroblast growth ( 243) 1171 291.0 9.3e-79
XP_006713601 (OMIM: 601513,617166) PREDICTED: fibr ( 178) 1166 289.8 1.6e-78
XP_016861368 (OMIM: 601513,617166) PREDICTED: fibr ( 157) 1039 259.1 2.5e-69
NP_001308867 (OMIM: 601515,609307) fibroblast grow ( 187) 928 232.3 3.4e-61
NP_001308869 (OMIM: 601515,609307) fibroblast grow ( 187) 928 232.3 3.4e-61
NP_001308862 (OMIM: 601515,609307) fibroblast grow ( 187) 928 232.3 3.4e-61
NP_004106 (OMIM: 601515,609307) fibroblast growth ( 247) 926 231.9 6.1e-61
NP_001308870 (OMIM: 601515,609307) fibroblast grow ( 185) 922 230.8 9.3e-61
NP_001308876 (OMIM: 601515,609307) fibroblast grow ( 200) 922 230.8 9.9e-61
NP_001308877 (OMIM: 601515,609307) fibroblast grow ( 213) 922 230.9 1e-60
NP_001308874 (OMIM: 601515,609307) fibroblast grow ( 213) 922 230.9 1e-60
NP_787125 (OMIM: 601515,609307) fibroblast growth ( 252) 922 230.9 1.2e-60
NP_001308865 (OMIM: 601515,609307) fibroblast grow ( 184) 920 230.3 1.3e-60
NP_001308861 (OMIM: 601515,609307) fibroblast grow ( 184) 920 230.3 1.3e-60
NP_001308873 (OMIM: 601515,609307) fibroblast grow ( 184) 920 230.3 1.3e-60
NP_001132970 (OMIM: 300070) fibroblast growth fact ( 199) 856 214.9 6.2e-56
NP_001132973 (OMIM: 300070) fibroblast growth fact ( 226) 851 213.7 1.6e-55
NP_001132974 (OMIM: 300070) fibroblast growth fact ( 226) 851 213.7 1.6e-55
NP_001132972 (OMIM: 300070) fibroblast growth fact ( 255) 851 213.8 1.8e-55
XP_005262456 (OMIM: 300070) PREDICTED: fibroblast ( 255) 851 213.8 1.8e-55
NP_378668 (OMIM: 300070) fibroblast growth factor ( 192) 845 212.2 3.8e-55
NP_004105 (OMIM: 300070) fibroblast growth factor ( 245) 845 212.3 4.7e-55
NP_001308871 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308864 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308878 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308875 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308860 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308863 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308872 (OMIM: 601515,609307) fibroblast grow ( 163) 814 204.7 5.9e-53
NP_001308868 (OMIM: 601515,609307) fibroblast grow ( 215) 733 185.2 5.8e-47
NP_001290389 (OMIM: 601514) fibroblast growth fact ( 166) 709 179.4 2.6e-45
NP_004103 (OMIM: 601514) fibroblast growth factor ( 225) 705 178.5 6.6e-45
NP_001308866 (OMIM: 601515,609307) fibroblast grow ( 159) 396 103.8 1.4e-22
NP_002001 (OMIM: 600921,612961) fibroblast growth ( 208) 385 101.2 1.1e-21
NP_062825 (OMIM: 605558,615721) fibroblast growth ( 211) 383 100.7 1.6e-21
NP_003859 (OMIM: 300827,309630) fibroblast growth ( 207) 369 97.3 1.6e-20
XP_005248321 (OMIM: 149730,180920,602115) PREDICTE ( 208) 317 84.7 9.9e-17
NP_004456 (OMIM: 149730,180920,602115) fibroblast ( 208) 317 84.7 9.9e-17
NP_004455 (OMIM: 165190,190330) fibroblast growth ( 268) 314 84.1 2e-16
NP_002000 (OMIM: 148180) fibroblast growth factor ( 194) 298 80.1 2.3e-15
NP_065688 (OMIM: 605831) fibroblast growth factor ( 170) 296 79.6 2.8e-15
NP_066276 (OMIM: 134921) fibroblast growth factor ( 208) 291 78.5 7.7e-15
XP_011533298 (OMIM: 600921,612961) PREDICTED: fibr ( 158) 287 77.4 1.2e-14
NP_001998 (OMIM: 164980) fibroblast growth factor ( 206) 278 75.3 6.8e-14
NP_001244134 (OMIM: 131220) fibroblast growth fact ( 155) 263 71.6 6.5e-13
NP_000791 (OMIM: 131220) fibroblast growth factor ( 155) 263 71.6 6.5e-13
NP_001244136 (OMIM: 131220) fibroblast growth fact ( 155) 263 71.6 6.5e-13
NP_001244139 (OMIM: 131220) fibroblast growth fact ( 155) 263 71.6 6.5e-13
>>NP_004104 (OMIM: 601513,617166) fibroblast growth fact (181 aa)
initn: 1195 init1: 1195 opt: 1195 Z-score: 1568.2 bits: 296.8 E(85289): 1.3e-80
Smith-Waterman score: 1195; 99.4% identity (99.4% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_004 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
130 140 150 160 170 180
pF1KE1 T
:
NP_004 T
>>XP_005247284 (OMIM: 601513,617166) PREDICTED: fibrobla (207 aa)
initn: 1171 init1: 1171 opt: 1171 Z-score: 1536.0 bits: 291.0 E(85289): 8.1e-79
Smith-Waterman score: 1171; 99.4% identity (99.4% similar) in 177 aa overlap (5-181:31-207)
10 20 30
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGT
::::::::::::::::::::::::::::::
XP_005 MKILELSLKKGVHMLQCLCGRSLRSSDSPSEPQLKGIVTRLFSQQGYFLQMHPDGTIDGT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 KDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 VIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 VIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEI
130 140 150 160 170 180
160 170 180
pF1KE1 GEKQGRSRKSSGTPTMNGGKVVNQDST
:::::::::::::::::::::::::::
XP_005 GEKQGRSRKSSGTPTMNGGKVVNQDST
190 200
>>NP_066360 (OMIM: 601513,617166) fibroblast growth fact (243 aa)
initn: 1171 init1: 1171 opt: 1171 Z-score: 1535.0 bits: 291.0 E(85289): 9.3e-79
Smith-Waterman score: 1171; 99.4% identity (99.4% similar) in 177 aa overlap (5-181:67-243)
10 20 30
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGT
::::::::::::::::::::::::::::::
NP_066 GRSLCERHVLGVFSKVRFCSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGT
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 KDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYY
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 VIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_066 VIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEI
160 170 180 190 200 210
160 170 180
pF1KE1 GEKQGRSRKSSGTPTMNGGKVVNQDST
:::::::::::::::::::::::::::
NP_066 GEKQGRSRKSSGTPTMNGGKVVNQDST
220 230 240
>>XP_006713601 (OMIM: 601513,617166) PREDICTED: fibrobla (178 aa)
initn: 1166 init1: 1166 opt: 1166 Z-score: 1530.5 bits: 289.8 E(85289): 1.6e-78
Smith-Waterman score: 1166; 98.9% identity (99.4% similar) in 177 aa overlap (5-181:2-178)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_006 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
120 130 140 150 160 170
pF1KE1 T
:
XP_006 T
>>XP_016861368 (OMIM: 601513,617166) PREDICTED: fibrobla (157 aa)
initn: 1039 init1: 1039 opt: 1039 Z-score: 1365.6 bits: 259.1 E(85289): 2.5e-69
Smith-Waterman score: 1039; 99.4% identity (99.4% similar) in 157 aa overlap (25-181:1-157)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
::::::::::::::::::::::::::::::::::::
XP_016 MHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
10 20 30
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_016 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
100 110 120 130 140 150
pF1KE1 T
:
XP_016 T
>>NP_001308867 (OMIM: 601515,609307) fibroblast growth f (187 aa)
initn: 919 init1: 881 opt: 928 Z-score: 1219.5 bits: 232.3 E(85289): 3.4e-61
Smith-Waterman score: 928; 73.7% identity (89.8% similar) in 186 aa overlap (1-181:1-186)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
: ..::::::::::. .:::.:::::::..:::::.... :::::::::::::::::::
NP_001 MPREDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
..::.::::::::: :..::::::::::::::::::::: ::::::::::::::::::::
NP_001 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGE---KQGR--SRKSSGTPTMNGGKV
:::::::::::..::.:::.:: :::: :::..:: : : :...:.. :::::
NP_001 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
130 140 150 160 170 180
180
pF1KE1 VNQDST
::...:
NP_001 VNKSKTT
>>NP_001308869 (OMIM: 601515,609307) fibroblast growth f (187 aa)
initn: 919 init1: 881 opt: 928 Z-score: 1219.5 bits: 232.3 E(85289): 3.4e-61
Smith-Waterman score: 928; 73.7% identity (89.8% similar) in 186 aa overlap (1-181:1-186)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
: ..::::::::::. .:::.:::::::..:::::.... :::::::::::::::::::
NP_001 MPREDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
..::.::::::::: :..::::::::::::::::::::: ::::::::::::::::::::
NP_001 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGE---KQGR--SRKSSGTPTMNGGKV
:::::::::::..::.:::.:: :::: :::..:: : : :...:.. :::::
NP_001 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
130 140 150 160 170 180
180
pF1KE1 VNQDST
::...:
NP_001 VNKSKTT
>>NP_001308862 (OMIM: 601515,609307) fibroblast growth f (187 aa)
initn: 919 init1: 881 opt: 928 Z-score: 1219.5 bits: 232.3 E(85289): 3.4e-61
Smith-Waterman score: 928; 73.7% identity (89.8% similar) in 186 aa overlap (1-181:1-186)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
: ..::::::::::. .:::.:::::::..:::::.... :::::::::::::::::::
NP_001 MPREDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
..::.::::::::: :..::::::::::::::::::::: ::::::::::::::::::::
NP_001 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGE---KQGR--SRKSSGTPTMNGGKV
:::::::::::..::.:::.:: :::: :::..:: : : :...:.. :::::
NP_001 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
130 140 150 160 170 180
180
pF1KE1 VNQDST
::...:
NP_001 VNKSKTT
>>NP_004106 (OMIM: 601515,609307) fibroblast growth fact (247 aa)
initn: 917 init1: 879 opt: 926 Z-score: 1215.1 bits: 231.9 E(85289): 6.1e-61
Smith-Waterman score: 926; 73.1% identity (90.3% similar) in 186 aa overlap (1-181:61-246)
10 20 30
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGT
.. ..::::::::::. .:::.:::::::.
NP_004 SSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGA
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE1 IDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVF
.:::::.... :::::::::::::::::::..::.::::::::: :..::::::::::::
NP_004 LDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVF
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE1 ENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREQS
::::::::: :::::::::::::::::::: :::::::::::..::.:::.:: :::: :
NP_004 ENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPS
160 170 180 190 200 210
160 170 180
pF1KE1 LHEIGE---KQGR--SRKSSGTPTMNGGKVVNQDST
::..:: : : :...:.. ::::: ::...:
NP_004 LHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
220 230 240
>>NP_001308870 (OMIM: 601515,609307) fibroblast growth f (185 aa)
initn: 913 init1: 875 opt: 922 Z-score: 1211.8 bits: 230.8 E(85289): 9.3e-61
Smith-Waterman score: 922; 74.7% identity (90.7% similar) in 182 aa overlap (5-181:3-184)
10 20 30 40 50 60
pF1KE1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
.::::::::::. .:::.:::::::..:::::.... :::::::::::::::::::
NP_001 MTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
..::.::::::::: :..::::::::::::::::::::: ::::::::::::::::::::
NP_001 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
60 70 80 90 100 110
130 140 150 160 170
pF1KE1 IMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGE---KQGR--SRKSSGTPTMNGGKV
:::::::::::..::.:::.:: :::: :::..:: : : :...:.. :::::
NP_001 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
120 130 140 150 160 170
180
pF1KE1 VNQDST
::...:
NP_001 VNKSKTT
180
181 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:38:42 2016 done: Mon Nov 7 00:38:43 2016
Total Scan time: 5.450 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]