Result of FASTA (omim) for
pFN21AE1458
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1458, 271 aa
1>>>pF1KE1458 271 - 271 aa - 271 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3705+/-0.000328; mu= 20.1569+/- 0.020
mean_var=56.1835+/-11.319, 0's: 0 Z-trim(115.0): 38 B-trim: 872 in 1/51
Lambda= 0.171108
statistics sampled from 25162 (25187) to 25162 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.295), width: 16
Scan time: 5.400
The best scores are: opt bits E(85289)
NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor ( 271) 1843 462.7 3.3e-130
XP_016884719 (OMIM: 300927) PREDICTED: peroxiredox ( 350) 1737 436.6 3e-122
XP_005274495 (OMIM: 300927) PREDICTED: peroxiredox ( 257) 1303 329.4 4.2e-90
XP_016884720 (OMIM: 300927) PREDICTED: peroxiredox ( 336) 1197 303.3 3.9e-82
NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sap ( 198) 957 243.9 1.8e-64
NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo ( 199) 951 242.4 5e-64
NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 951 242.4 5e-64
NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 951 242.4 5e-64
NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 951 242.4 5e-64
NP_006784 (OMIM: 604769) thioredoxin-dependent per ( 256) 911 232.6 5.6e-61
NP_001289201 (OMIM: 604769) thioredoxin-dependent ( 198) 580 150.8 1.8e-36
NP_004896 (OMIM: 602316) peroxiredoxin-6 [Homo sap ( 224) 142 42.7 0.00071
NP_036226 (OMIM: 606583) peroxiredoxin-5, mitochon ( 214) 136 41.2 0.0019
>>NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor [Ho (271 aa)
initn: 1843 init1: 1843 opt: 1843 Z-score: 2458.7 bits: 462.7 E(85289): 3.3e-130
Smith-Waterman score: 1843; 100.0% identity (100.0% similar) in 271 aa overlap (1-271:1-271)
10 20 30 40 50 60
pF1KE1 MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 THQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 THQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK
190 200 210 220 230 240
250 260 270
pF1KE1 HGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::::::::::::::::::::::::
NP_006 HGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
250 260 270
>>XP_016884719 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (350 aa)
initn: 1737 init1: 1737 opt: 1737 Z-score: 2315.8 bits: 436.6 E(85289): 3e-122
Smith-Waterman score: 1737; 99.6% identity (100.0% similar) in 256 aa overlap (1-256:1-256)
10 20 30 40 50 60
pF1KE1 MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 THQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK
190 200 210 220 230 240
250 260 270
pF1KE1 HGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::::::::.
XP_016 HGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPALWEAEAGRSRGQEM
250 260 270 280 290 300
>>XP_005274495 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (257 aa)
initn: 1303 init1: 1303 opt: 1303 Z-score: 1738.6 bits: 329.4 E(85289): 4.2e-90
Smith-Waterman score: 1303; 99.5% identity (100.0% similar) in 191 aa overlap (81-271:67-257)
60 70 80 90 100 110
pF1KE1 CHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKY
.:::::::::::::::::::::::::::::
XP_005 EGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYRGKY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
160 170 180 190 200 210
240 250 260 270
pF1KE1 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::::::::::::::::::::::::::::::::::
XP_005 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
220 230 240 250
>>XP_016884720 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (336 aa)
initn: 1193 init1: 1193 opt: 1197 Z-score: 1595.6 bits: 303.3 E(85289): 3.9e-82
Smith-Waterman score: 1197; 98.9% identity (100.0% similar) in 176 aa overlap (81-256:67-242)
60 70 80 90 100 110
pF1KE1 CHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKY
.:::::::::::::::::::::::::::::
XP_016 EGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYRGKY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
160 170 180 190 200 210
240 250 260 270
pF1KE1 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::::::::::::::::::.
XP_016 LVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPALWEA
220 230 240 250 260 270
>>NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sapiens (198 aa)
initn: 960 init1: 944 opt: 957 Z-score: 1278.5 bits: 243.9 E(85289): 1.8e-64
Smith-Waterman score: 957; 70.5% identity (90.2% similar) in 193 aa overlap (79-271:6-198)
50 60 70 80 90 100
pF1KE1 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRG
:.:.:::: ...:::.:: :::.::.::.:
NP_005 MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKG
10 20 30
110 120 130 140 150 160
pF1KE1 KYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGG
::.:.::::::::::::::::::..: :.::... ::.. ::::::::::::::::..::
NP_005 KYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 LGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDET
:::. ::::.:.:...:.:::: : : . ::::::: ::.:::::.:::::::::::.
NP_005 LGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEA
100 110 120 130 140 150
230 240 250 260 270
pF1KE1 LRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::::.:::::::::::::.:: :. . .::.: :
NP_005 LRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN
160 170 180 190
>>NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo sapi (199 aa)
initn: 966 init1: 905 opt: 951 Z-score: 1270.5 bits: 242.4 E(85289): 5e-64
Smith-Waterman score: 951; 70.3% identity (89.6% similar) in 192 aa overlap (79-269:6-197)
50 60 70 80 90 100
pF1KE1 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVI-DGEFKELKLTDYR
:::..::: ...:::. ::.::...:.::.
NP_001 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYK
10 20 30
110 120 130 140 150 160
pF1KE1 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..::
NP_001 GKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
::::. :::.:: . :..:::: : : ..::::::::::::::::.:::::::::::
NP_001 GLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDE
100 110 120 130 140 150
230 240 250 260 270
pF1KE1 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::.::::::::::::::::.:: :: . .::.:
NP_001 TLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 966 init1: 905 opt: 951 Z-score: 1270.5 bits: 242.4 E(85289): 5e-64
Smith-Waterman score: 951; 70.3% identity (89.6% similar) in 192 aa overlap (79-269:6-197)
50 60 70 80 90 100
pF1KE1 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVI-DGEFKELKLTDYR
:::..::: ...:::. ::.::...:.::.
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYK
10 20 30
110 120 130 140 150 160
pF1KE1 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..::
NP_859 GKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
::::. :::.:: . :..:::: : : ..::::::::::::::::.:::::::::::
NP_859 GLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDE
100 110 120 130 140 150
230 240 250 260 270
pF1KE1 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::.::::::::::::::::.:: :: . .::.:
NP_859 TLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 966 init1: 905 opt: 951 Z-score: 1270.5 bits: 242.4 E(85289): 5e-64
Smith-Waterman score: 951; 70.3% identity (89.6% similar) in 192 aa overlap (79-269:6-197)
50 60 70 80 90 100
pF1KE1 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVI-DGEFKELKLTDYR
:::..::: ...:::. ::.::...:.::.
NP_002 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYK
10 20 30
110 120 130 140 150 160
pF1KE1 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..::
NP_002 GKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
::::. :::.:: . :..:::: : : ..::::::::::::::::.:::::::::::
NP_002 GLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDE
100 110 120 130 140 150
230 240 250 260 270
pF1KE1 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::.::::::::::::::::.:: :: . .::.:
NP_002 TLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 966 init1: 905 opt: 951 Z-score: 1270.5 bits: 242.4 E(85289): 5e-64
Smith-Waterman score: 951; 70.3% identity (89.6% similar) in 192 aa overlap (79-269:6-197)
50 60 70 80 90 100
pF1KE1 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVI-DGEFKELKLTDYR
:::..::: ...:::. ::.::...:.::.
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYK
10 20 30
110 120 130 140 150 160
pF1KE1 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..::
NP_859 GKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
::::. :::.:: . :..:::: : : ..::::::::::::::::.:::::::::::
NP_859 GLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDE
100 110 120 130 140 150
230 240 250 260 270
pF1KE1 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
:::::::::.::::::::::::::::.:: :: . .::.:
NP_859 TLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_006784 (OMIM: 604769) thioredoxin-dependent peroxid (256 aa)
initn: 924 init1: 905 opt: 911 Z-score: 1215.7 bits: 232.6 E(85289): 5.6e-61
Smith-Waterman score: 911; 66.5% identity (90.6% similar) in 191 aa overlap (81-271:65-255)
60 70 80 90 100 110
pF1KE1 CHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKY
... :::..::::..::::.:.: :..:::
NP_006 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
NP_006 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
. : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
NP_006 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
160 170 180 190 200 210
240 250 260 270
pF1KE1 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
::.::::.. :::::::.: : : :: :.::.. .::.:.:
NP_006 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
220 230 240 250
271 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:20:03 2016 done: Sun Nov 6 23:20:04 2016
Total Scan time: 5.400 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]