Result of FASTA (omim) for
pFN21AE1456
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1456, 170 aa
1>>>pF1KE1456 170 - 170 aa - 170 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0729+/-0.000259; mu= 14.9706+/- 0.016
mean_var=72.3819+/-14.286, 0's: 0 Z-trim(122.0): 39 B-trim: 0 in 0/50
Lambda= 0.150751
statistics sampled from 39288 (39329) to 39288 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.461), width: 16
Scan time: 5.600
The best scores are: opt bits E(85289)
NP_002623 (OMIM: 601121) placenta growth factor is ( 170) 1212 271.4 4.8e-73
NP_001280572 (OMIM: 601121) placenta growth factor ( 169) 1193 267.3 8.4e-72
NP_001193941 (OMIM: 601121) placenta growth factor ( 149) 992 223.5 1.1e-58
NP_001165096 (OMIM: 192240,603933) vascular endoth ( 209) 499 116.4 2.7e-26
NP_001020538 (OMIM: 192240,603933) vascular endoth ( 389) 499 116.7 4.3e-26
NP_001191313 (OMIM: 192240,603933) vascular endoth ( 171) 491 114.6 7.7e-26
NP_001191314 (OMIM: 192240,603933) vascular endoth ( 351) 491 114.9 1.3e-25
NP_001165095 (OMIM: 192240,603933) vascular endoth ( 215) 488 114.1 1.4e-25
NP_003367 (OMIM: 192240,603933) vascular endotheli ( 395) 488 114.3 2.3e-25
NP_001165094 (OMIM: 192240,603933) vascular endoth ( 232) 479 112.1 5.9e-25
NP_001020537 (OMIM: 192240,603933) vascular endoth ( 412) 479 112.3 9.2e-25
NP_001165098 (OMIM: 192240,603933) vascular endoth ( 174) 452 106.2 2.8e-23
NP_001165100 (OMIM: 192240,603933) vascular endoth ( 191) 452 106.2 3e-23
NP_001165097 (OMIM: 192240,603933) vascular endoth ( 191) 452 106.2 3e-23
NP_001303939 (OMIM: 192240,603933) vascular endoth ( 213) 452 106.2 3.3e-23
NP_001273973 (OMIM: 192240,603933) vascular endoth ( 163) 450 105.7 3.6e-23
NP_001020540 (OMIM: 192240,603933) vascular endoth ( 354) 452 106.4 4.8e-23
NP_001020539 (OMIM: 192240,603933) vascular endoth ( 371) 452 106.4 5e-23
NP_001028928 (OMIM: 192240,603933) vascular endoth ( 371) 452 106.4 5e-23
NP_001165099 (OMIM: 192240,603933) vascular endoth ( 147) 437 102.8 2.4e-22
NP_001020541 (OMIM: 192240,603933) vascular endoth ( 327) 437 103.1 4.3e-22
NP_001165101 (OMIM: 192240,603933) vascular endoth ( 137) 410 96.9 1.3e-20
NP_001165093 (OMIM: 192240,603933) vascular endoth ( 317) 410 97.2 2.5e-20
NP_001230662 (OMIM: 601398) vascular endothelial g ( 188) 291 71.2 1e-12
NP_003368 (OMIM: 601398) vascular endothelial grow ( 207) 278 68.4 7.8e-12
NP_004460 (OMIM: 300091) vascular endothelial grow ( 354) 226 57.2 3e-08
NP_005420 (OMIM: 601528,615907) vascular endotheli ( 419) 210 53.8 3.8e-07
XP_011513721 (OMIM: 173430) PREDICTED: platelet-de ( 210) 189 49.0 5.3e-06
NP_002598 (OMIM: 173430) platelet-derived growth f ( 211) 189 49.0 5.3e-06
XP_016867778 (OMIM: 173430) PREDICTED: platelet-de ( 224) 189 49.0 5.6e-06
XP_011513718 (OMIM: 173430) PREDICTED: platelet-de ( 249) 189 49.1 6.1e-06
XP_011513717 (OMIM: 173430) PREDICTED: platelet-de ( 256) 189 49.1 6.2e-06
NP_148937 (OMIM: 190040,213600,607174,607907,61548 ( 226) 167 44.3 0.00016
NP_002599 (OMIM: 190040,213600,607174,607907,61548 ( 241) 167 44.3 0.00016
NP_148983 (OMIM: 173430) platelet-derived growth f ( 196) 153 41.2 0.0011
XP_011513720 (OMIM: 173430) PREDICTED: platelet-de ( 234) 153 41.2 0.0013
XP_011513719 (OMIM: 173430) PREDICTED: platelet-de ( 241) 153 41.2 0.0013
>>NP_002623 (OMIM: 601121) placenta growth factor isofor (170 aa)
initn: 1212 init1: 1212 opt: 1212 Z-score: 1432.4 bits: 271.4 E(85289): 4.8e-73
Smith-Waterman score: 1212; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR
130 140 150 160 170
>>NP_001280572 (OMIM: 601121) placenta growth factor iso (169 aa)
initn: 1044 init1: 1044 opt: 1193 Z-score: 1410.1 bits: 267.3 E(85289): 8.4e-72
Smith-Waterman score: 1193; 99.4% identity (99.4% similar) in 170 aa overlap (1-170:1-169)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 MPVMRLFPCFLQLLAGLALPAVPPQ-WALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
60 70 80 90 100 110
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR
120 130 140 150 160
>>NP_001193941 (OMIM: 601121) placenta growth factor iso (149 aa)
initn: 1041 init1: 992 opt: 992 Z-score: 1174.6 bits: 223.5 E(85289): 1.1e-58
Smith-Waterman score: 1003; 87.6% identity (87.6% similar) in 170 aa overlap (1-170:1-149)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR
::::::::::::::::::::: ::::::::
NP_001 TFSQHVRCECRPLREKMKPER---------------------CGDAVPRR
130 140
>>NP_001165096 (OMIM: 192240,603933) vascular endothelia (209 aa)
initn: 488 init1: 456 opt: 499 Z-score: 593.1 bits: 116.4 E(85289): 2.7e-26
Smith-Waterman score: 499; 45.6% identity (74.5% similar) in 149 aa overlap (25-170:25-168)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
: .. :.:... ::: :..:. ::::. .: :::
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. . :.
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHLCGDAVPRR
.: :: .::::: ... . :.. : ::.: ::.:.:.:: :: ::
NP_001 SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRP-----CGPCSERRKHLFVQD
130 140 150 160 170
NP_001 PQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
180 190 200
>>NP_001020538 (OMIM: 192240,603933) vascular endothelia (389 aa)
initn: 473 init1: 456 opt: 499 Z-score: 589.4 bits: 116.7 E(85289): 4.3e-26
Smith-Waterman score: 499; 45.6% identity (74.5% similar) in 149 aa overlap (25-170:205-348)
10 20 30 40 50
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRA
: .. :.:... ::: :..:. ::::.
NP_001 GRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHP
180 190 200 210 220 230
60 70 80 90 100 110
pF1KE1 LERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDR
.: :::. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. .
NP_001 IETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQG
240 250 260 270 280 290
120 130 140 150 160 170
pF1KE1 PSYVELTFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHLCGDAVPRR
:..: :: .::::: ... . :.. : ::.: ::.:.:.:: :: ::
NP_001 QHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRP-----CGPCSERRK
300 310 320 330 340
NP_001 HLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
350 360 370 380
>>NP_001191313 (OMIM: 192240,603933) vascular endothelia (171 aa)
initn: 487 init1: 456 opt: 491 Z-score: 584.9 bits: 114.6 E(85289): 7.7e-26
Smith-Waterman score: 491; 45.0% identity (75.2% similar) in 149 aa overlap (25-170:25-171)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
: .. :.:... ::: :..:. ::::. .: :::
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. . :.
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHLCGDAVPRR
.: :: .::::: ... . :.. : ::.: ::.:.:.: . .: :::
NP_001 SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVCDK--PRR
130 140 150 160 170
>>NP_001191314 (OMIM: 192240,603933) vascular endothelia (351 aa)
initn: 456 init1: 456 opt: 491 Z-score: 580.6 bits: 114.9 E(85289): 1.3e-25
Smith-Waterman score: 491; 45.0% identity (75.2% similar) in 149 aa overlap (25-170:205-351)
10 20 30 40 50
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRA
: .. :.:... ::: :..:. ::::.
NP_001 GRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHP
180 190 200 210 220 230
60 70 80 90 100 110
pF1KE1 LERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDR
.: :::. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. .
NP_001 IETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQG
240 250 260 270 280 290
120 130 140 150 160 170
pF1KE1 PSYVELTFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHLCGDAVPRR
:..: :: .::::: ... . :.. : ::.: ::.:.:.: . .: :::
NP_001 QHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVCDK--PRR
300 310 320 330 340 350
>>NP_001165095 (OMIM: 192240,603933) vascular endothelia (215 aa)
initn: 471 init1: 456 opt: 488 Z-score: 580.0 bits: 114.1 E(85289): 1.4e-25
Smith-Waterman score: 488; 44.7% identity (74.7% similar) in 150 aa overlap (25-170:25-174)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
: .. :.:... ::: :..:. ::::. .: :::
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. . :.
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHL-CGDAVPRR
.: :: .::::: ... . :.. : ::.: ::.:.:.: . . :: ::
NP_001 SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQ
130 140 150 160 170 180
NP_001 DPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
190 200 210
>>NP_003367 (OMIM: 192240,603933) vascular endothelial g (395 aa)
initn: 456 init1: 456 opt: 488 Z-score: 576.4 bits: 114.3 E(85289): 2.3e-25
Smith-Waterman score: 488; 44.7% identity (74.7% similar) in 150 aa overlap (25-170:205-354)
10 20 30 40 50
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRA
: .. :.:... ::: :..:. ::::.
NP_003 GRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHP
180 190 200 210 220 230
60 70 80 90 100 110
pF1KE1 LERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDR
.: :::. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. .
NP_003 IETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQG
240 250 260 270 280 290
120 130 140 150 160 170
pF1KE1 PSYVELTFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHL-CGDAVPRR
:..: :: .::::: ... . :.. : ::.: ::.:.:.: . . :: ::
NP_003 QHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERR
300 310 320 330 340 350
NP_003 KHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
360 370 380 390
>>NP_001165094 (OMIM: 192240,603933) vascular endothelia (232 aa)
initn: 493 init1: 456 opt: 479 Z-score: 569.0 bits: 112.1 E(85289): 5.9e-25
Smith-Waterman score: 479; 46.7% identity (78.5% similar) in 135 aa overlap (25-156:25-159)
10 20 30 40 50 60
pF1KE1 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
: .. :.:... ::: :..:. ::::. .: :::
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
. .:::.:.:..:.:::: :.:: :::.::.:.:::.: .:.:::...:. . :.
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 TFSQHVRCECRPLREKMKPERR--RPKGRG-KRRREKQRPTDCHLCGDAVPRR
.: :: .::::: ... . :.. : ::.: ::.:.:.:
NP_001 SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSLPG
130 140 150 160 170 180
NP_001 PHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
190 200 210 220 230
170 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:50:49 2016 done: Mon Nov 7 02:50:50 2016
Total Scan time: 5.600 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]