Result of FASTA (omim) for
pFN21AE1446
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1446, 325 aa
1>>>pF1KE1446 325 - 325 aa - 325 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2022+/-0.000549; mu= 11.2456+/- 0.034
mean_var=130.4174+/-28.333, 0's: 0 Z-trim(110.8): 271 B-trim: 182 in 1/48
Lambda= 0.112307
statistics sampled from 18928 (19282) to 18928 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.226), width: 16
Scan time: 6.630
The best scores are: opt bits E(85289)
NP_003748 (OMIM: 603911) eukaryotic translation in ( 325) 2225 372.5 6.5e-103
XP_016858160 (OMIM: 603911) PREDICTED: eukaryotic ( 192) 991 172.4 6.9e-43
XP_011534221 (OMIM: 612870) PREDICTED: PH-interact (1001) 228 49.5 3.6e-05
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 219 47.5 4.6e-05
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 219 47.5 4.6e-05
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 219 47.5 4.6e-05
XP_011534220 (OMIM: 612870) PREDICTED: PH-interact (1649) 228 49.7 5.1e-05
XP_005248786 (OMIM: 612870) PREDICTED: PH-interact (1820) 228 49.7 5.4e-05
NP_060404 (OMIM: 612870) PH-interacting protein [H (1821) 228 49.7 5.4e-05
XP_016884874 (OMIM: 300553,300659) PREDICTED: brom ( 825) 212 46.8 0.00019
XP_005262170 (OMIM: 300553,300659) PREDICTED: brom (1752) 212 47.1 0.00032
NP_694984 (OMIM: 300553,300659) bromodomain and WD (1802) 212 47.1 0.00032
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 198 44.2 0.00051
NP_001078 (OMIM: 603488) angio-associated migrator ( 434) 197 44.1 0.00065
NP_001289474 (OMIM: 603488) angio-associated migra ( 435) 197 44.1 0.00065
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 176 40.8 0.008
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 176 40.8 0.0085
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 176 40.8 0.0089
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 176 40.9 0.0094
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 176 40.9 0.0094
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 176 40.9 0.0096
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 176 40.9 0.0096
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 176 40.9 0.0096
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 176 40.9 0.0096
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 176 40.9 0.0096
>>NP_003748 (OMIM: 603911) eukaryotic translation initia (325 aa)
initn: 2225 init1: 2225 opt: 2225 Z-score: 1968.7 bits: 372.5 E(85289): 6.5e-103
Smith-Waterman score: 2225; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 YDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSY
250 260 270 280 290 300
310 320
pF1KE1 SSGGEDGYVRIHYFDPQYFEFEFEA
:::::::::::::::::::::::::
NP_003 SSGGEDGYVRIHYFDPQYFEFEFEA
310 320
>>XP_016858160 (OMIM: 603911) PREDICTED: eukaryotic tran (192 aa)
initn: 991 init1: 991 opt: 991 Z-score: 891.0 bits: 172.4 E(85289): 6.9e-43
Smith-Waterman score: 991; 99.3% identity (100.0% similar) in 150 aa overlap (176-325:43-192)
150 160 170 180 190 200
pF1KE1 DSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVT
.:::::::::::::::::::::::::::::
XP_016 ELCGVWTLTGTPSMSSLAQLTTAVVSGTVKQSGEVLVNVKEHSRQINDIQLSRDMTMFVT
20 30 40 50 60 70
210 220 230 240 250 260
pF1KE1 ASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKF
80 90 100 110 120 130
270 280 290 300 310 320
pF1KE1 EARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA
140 150 160 170 180 190
>>XP_011534221 (OMIM: 612870) PREDICTED: PH-interacting (1001 aa)
initn: 230 init1: 165 opt: 228 Z-score: 213.9 bits: 49.5 E(85289): 3.6e-05
Smith-Waterman score: 240; 22.8% identity (54.7% similar) in 316 aa overlap (8-309:181-491)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVW
:: :. . ..: : .:: . : .:..:
XP_011 FSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIW
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE1 YSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSA-V
. .:. :.: ::.. . . ..... . .:: :. :.: .: ::.:. .:: .
XP_011 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE1 RTCGFD--FGGNIIMFSTDKQMGYQCFVSFFDLRDPSQID-NNEP--YMKIPCNDSKITS
. :. .:. ..:. : :: : : . . : .: . . : ..
XP_011 TSLQFSPLCSGSKRYLSSTGADGTICFW----LWDAGTLKINPRPAKFTERPRPGVQMIC
280 290 300 310 320
160 170 180 190 200
pF1KE1 AVWGPLGECIIAGHESGELNQYSAKSG--EVLVNVKEHSRQINDIQLSRDMTMFVTASKD
. .. : . .: . . : :: : . ... :. ....::.: . ::..:.:
XP_011 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD
330 340 350 360 370 380
210 220 230 240 250 260
pF1KE1 NTAKLFDSTTLEHQKTF--RTERPVNSAALSPNYDHVV-LGGGQEAMDV--TTTSTRIGK
.::.... : .. . . ::... :. :... . . : : .:. : ...
XP_011 GTARIWQFKRREWKSILLDMATRPAGQN-LQGIEDKITKMKVTMVAWDRHDNTVITAVNN
390 400 410 420 430 440
270 280 290 300 310 320
pF1KE1 FEARFFHLAFEEEFGRVKGHFGPINSVAFHP-DGKSYSSGGEDGYVRIHYFDPQYFEFEF
. . .. . . . :: . . :: : . :.:.:: :
XP_011 MTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSY
450 460 470 480 490 500
pF1KE1 EA
XP_011 FNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPL
510 520 530 540 550 560
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 255 init1: 197 opt: 219 Z-score: 212.0 bits: 47.5 E(85289): 4.6e-05
Smith-Waterman score: 246; 24.1% identity (59.0% similar) in 249 aa overlap (6-227:83-328)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVN
..::. .:... .. ...:: ... : ..
NP_060 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE1 VWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNS-
.: .:. : : ::.. :.: . . ... ...:: :.: :.:: .::: : : ..:
NP_060 IWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSD
120 130 140 150 160 170
100 110 120 130 140
pF1KE1 AVRTCGFDFGGNIIMFST--------DKQMGYQCFVSFFDLRDPS----QIDNNEPYMKI
: . :. :..:. :. : : ::. ...: .: ... : :.
NP_060 PVSAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPPVSFVKFSPNGKYILA
180 190 200 210 220 230
150 160 170 180 190
pF1KE1 PCNDSKITSAVWG-PLGECI--IAGHESGE---LNQYSAKSGEVLVNVKEHSR------Q
:. : .: :.:. .::.. . . ..:. .:. .:. .: . :
NP_060 ATLDN--TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQ
240 250 260 270 280
200 210 220 230 240
pF1KE1 INDI--QLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGG
..: .:. . .... : ... :..::..::..
NP_060 TKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
250 260 270 280 290 300
pF1KE1 GQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGY
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 255 init1: 197 opt: 219 Z-score: 212.0 bits: 47.5 E(85289): 4.6e-05
Smith-Waterman score: 246; 24.1% identity (59.0% similar) in 249 aa overlap (6-227:83-328)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVN
..::. .:... .. ...:: ... : ..
NP_438 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE1 VWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNS-
.: .:. : : ::.. :.: . . ... ...:: :.: :.:: .::: : : ..:
NP_438 IWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSD
120 130 140 150 160 170
100 110 120 130 140
pF1KE1 AVRTCGFDFGGNIIMFST--------DKQMGYQCFVSFFDLRDPS----QIDNNEPYMKI
: . :. :..:. :. : : ::. ...: .: ... : :.
NP_438 PVSAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPPVSFVKFSPNGKYILA
180 190 200 210 220 230
150 160 170 180 190
pF1KE1 PCNDSKITSAVWG-PLGECI--IAGHESGE---LNQYSAKSGEVLVNVKEHSR------Q
:. : .: :.:. .::.. . . ..:. .:. .:. .: . :
NP_438 ATLDN--TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQ
240 250 260 270 280
200 210 220 230 240
pF1KE1 INDI--QLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGG
..: .:. . .... : ... :..::..::..
NP_438 TKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
250 260 270 280 290 300
pF1KE1 GQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGY
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 255 init1: 197 opt: 219 Z-score: 212.0 bits: 47.5 E(85289): 4.6e-05
Smith-Waterman score: 246; 24.1% identity (59.0% similar) in 249 aa overlap (6-227:83-328)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVN
..::. .:... .. ...:: ... : ..
XP_005 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE1 VWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNS-
.: .:. : : ::.. :.: . . ... ...:: :.: :.:: .::: : : ..:
XP_005 IWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSD
120 130 140 150 160 170
100 110 120 130 140
pF1KE1 AVRTCGFDFGGNIIMFST--------DKQMGYQCFVSFFDLRDPS----QIDNNEPYMKI
: . :. :..:. :. : : ::. ...: .: ... : :.
XP_005 PVSAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLKTLIDDDNPPVSFVKFSPNGKYILA
180 190 200 210 220 230
150 160 170 180 190
pF1KE1 PCNDSKITSAVWG-PLGECI--IAGHESGE---LNQYSAKSGEVLVNVKEHSR------Q
:. : .: :.:. .::.. . . ..:. .:. .:. .: . :
XP_005 ATLDN--TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQ
240 250 260 270 280
200 210 220 230 240
pF1KE1 INDI--QLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGG
..: .:. . .... : ... :..::..::..
XP_005 TKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
250 260 270 280 290 300
pF1KE1 GQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGY
>>XP_011534220 (OMIM: 612870) PREDICTED: PH-interacting (1649 aa)
initn: 230 init1: 165 opt: 228 Z-score: 211.2 bits: 49.7 E(85289): 5.1e-05
Smith-Waterman score: 240; 22.8% identity (54.7% similar) in 316 aa overlap (8-309:9-319)
10 20 30 40 50
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVD
:: :. . ..: : .:: . : .:..: . .:. :.: ::.. . .
XP_011 MKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSA-VRTCGFD--FGGNIIMFSTDKQM
..... . .:: :. :.: .: ::.:. .:: . . :. .:. ..:.
XP_011 VNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGAD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 GYQCFVSFFDLRDPSQID-NNEP--YMKIPCNDSKITSAVWGPLGECIIAGHESGELNQY
: :: : : . . : .: . . : .. . .. : . .: . . :
XP_011 GTICFW----LWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY
130 140 150 160 170
180 190 200 210 220
pF1KE1 SAKSG--EVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTF--RTE
:: : . ... :. ....::.: . ::..:.:.::.... : .. . .
XP_011 FFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMAT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 RPVNSAALSPNYDHVV-LGGGQEAMDV--TTTSTRIGKFEARFFHLAFEEEFGRVKGHFG
::... :. :... . . : : .:. : .... . .. . . . ::
XP_011 RPAGQN-LQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHED
240 250 260 270 280 290
290 300 310 320
pF1KE1 PINSVAFHP-DGKSYSSGGEDGYVRIHYFDPQYFEFEFEA
. . :: : . :.:.:: :
XP_011 EVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQ
300 310 320 330 340 350
>>XP_005248786 (OMIM: 612870) PREDICTED: PH-interacting (1820 aa)
initn: 230 init1: 165 opt: 228 Z-score: 210.6 bits: 49.7 E(85289): 5.4e-05
Smith-Waterman score: 240; 22.8% identity (54.7% similar) in 316 aa overlap (8-309:181-491)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVW
:: :. . ..: : .:: . : .:..:
XP_005 FSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIW
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE1 YSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSA-V
. .:. :.: ::.. . . ..... . .:: :. :.: .: ::.:. .:: .
XP_005 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE1 RTCGFD--FGGNIIMFSTDKQMGYQCFVSFFDLRDPSQID-NNEP--YMKIPCNDSKITS
. :. .:. ..:. : :: : : . . : .: . . : ..
XP_005 TSLQFSPLCSGSKRYLSSTGADGTICFW----LWDAGTLKINPRPAKFTERPRPGVQMIC
280 290 300 310 320
160 170 180 190 200
pF1KE1 AVWGPLGECIIAGHESGELNQYSAKSG--EVLVNVKEHSRQINDIQLSRDMTMFVTASKD
. .. : . .: . . : :: : . ... :. ....::.: . ::..:.:
XP_005 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD
330 340 350 360 370 380
210 220 230 240 250 260
pF1KE1 NTAKLFDSTTLEHQKTF--RTERPVNSAALSPNYDHVV-LGGGQEAMDV--TTTSTRIGK
.::.... : .. . . ::... :. :... . . : : .:. : ...
XP_005 GTARIWQFKRREWKSILLDMATRPAGQN-LQGIEDKITKMKVTMVAWDRHDNTVITAVNN
390 400 410 420 430 440
270 280 290 300 310 320
pF1KE1 FEARFFHLAFEEEFGRVKGHFGPINSVAFHP-DGKSYSSGGEDGYVRIHYFDPQYFEFEF
. . .. . . . :: . . :: : . :.:.:: :
XP_005 MTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSY
450 460 470 480 490 500
pF1KE1 EA
XP_005 FNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPL
510 520 530 540 550 560
>>NP_060404 (OMIM: 612870) PH-interacting protein [Homo (1821 aa)
initn: 230 init1: 165 opt: 228 Z-score: 210.6 bits: 49.7 E(85289): 5.4e-05
Smith-Waterman score: 240; 22.8% identity (54.7% similar) in 316 aa overlap (8-309:181-491)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVW
:: :. . ..: : .:: . : .:..:
NP_060 FSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIW
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE1 YSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSA-V
. .:. :.: ::.. . . ..... . .:: :. :.: .: ::.:. .:: .
NP_060 ATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASI
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE1 RTCGFD--FGGNIIMFSTDKQMGYQCFVSFFDLRDPSQID-NNEP--YMKIPCNDSKITS
. :. .:. ..:. : :: : : . . : .: . . : ..
NP_060 TSLQFSPLCSGSKRYLSSTGADGTICFW----LWDAGTLKINPRPAKFTERPRPGVQMIC
280 290 300 310 320
160 170 180 190 200
pF1KE1 AVWGPLGECIIAGHESGELNQYSAKSG--EVLVNVKEHSRQINDIQLSRDMTMFVTASKD
. .. : . .: . . : :: : . ... :. ....::.: . ::..:.:
NP_060 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRD
330 340 350 360 370 380
210 220 230 240 250 260
pF1KE1 NTAKLFDSTTLEHQKTF--RTERPVNSAALSPNYDHVV-LGGGQEAMDV--TTTSTRIGK
.::.... : .. . . ::... :. :... . . : : .:. : ...
NP_060 GTARIWQFKRREWKSILLDMATRPAGQN-LQGIEDKITKMKVTMVAWDRHDNTVITAVNN
390 400 410 420 430 440
270 280 290 300 310 320
pF1KE1 FEARFFHLAFEEEFGRVKGHFGPINSVAFHP-DGKSYSSGGEDGYVRIHYFDPQYFEFEF
. . .. . . . :: . . :: : . :.:.:: :
NP_060 MTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSY
450 460 470 480 490 500
pF1KE1 EA
NP_060 FNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPL
510 520 530 540 550 560
>>XP_016884874 (OMIM: 300553,300659) PREDICTED: bromodom (825 aa)
initn: 193 init1: 162 opt: 212 Z-score: 200.9 bits: 46.8 E(85289): 0.00019
Smith-Waterman score: 267; 23.5% identity (55.0% similar) in 327 aa overlap (8-315:178-496)
10 20 30
pF1KE1 MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVW
:: :. . ..: : .:: . : .:..:
XP_016 SARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIW
150 160 170 180 190 200
40 50 60 70 80 90
pF1KE1 YSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSA--
. .:. :.: ::.. . . ..... . .:: :. :.: .: .:.:. .::
XP_016 ATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASI
210 220 230 240 250 260
100 110 120 130 140
pF1KE1 --VRTCGFDFGGNIIMFSTDKQMGYQCF----VSFFDLRD-PSQI-DNNEPYMKIPCNDS
.. : : : . :: . : :: :. . .:: : .. . ..: ..: : :
XP_016 TSIQFCPSTKGTNRYLTSTGAD-GTICFWQWHVKTMKFRDRPVKFTERSRPGVQISC--S
270 280 290 300 310 320
150 160 170 180 190 200
pF1KE1 KITSAVWGPLGECIIAGHESGELNQY--SAKSGEVLVNVKEHSRQINDIQLSR--DMTMF
...:. : : .: . . : ... : ..... :. .. .:. : :
XP_016 SFSSG-----GMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF
330 340 350 360 370
210 220 230 240 250
pF1KE1 VTASKDNTAKLFDSTTLEHQK-TFRTERPVNSAALSPNYDHVV-LGGGQEAMDV--TTTS
:..:.:.::.... : .. .. ... : . :... : . : : ::.
XP_016 VSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVI
380 390 400 410 420 430
260 270 280 290 300 310
pF1KE1 TRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHP-DGKSYSSGGEDGYVRIHYFDPQY
: ...: . .. . . ..:: . . :: : . :.:.:: . : .:
XP_016 TAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGT
440 450 460 470 480 490
320
pF1KE1 FEFEFEA
XP_016 KIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHT
500 510 520 530 540 550
325 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:36:45 2016 done: Sun Nov 6 23:36:46 2016
Total Scan time: 6.630 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]