Result of FASTA (omim) for
pFN21AE1435
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1435, 277 aa
1>>>pF1KE1435 277 - 277 aa - 277 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2251+/-0.000415; mu= 15.5346+/- 0.026
mean_var=62.9882+/-12.580, 0's: 0 Z-trim(109.8): 88 B-trim: 0 in 0/52
Lambda= 0.161601
statistics sampled from 17947 (18038) to 17947 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.211), width: 16
Scan time: 6.350
The best scores are: opt bits E(85289)
NP_004337 (OMIM: 600636) caspase-3 preproprotein [ ( 277) 1855 441.3 9.3e-124
XP_011530603 (OMIM: 600636) PREDICTED: caspase-3 i ( 277) 1855 441.3 9.3e-124
NP_116786 (OMIM: 600636) caspase-3 preproprotein [ ( 277) 1855 441.3 9.3e-124
XP_011538562 (OMIM: 601761) PREDICTED: caspase-7 i ( 270) 942 228.4 1.1e-59
NP_001253987 (OMIM: 601761) caspase-7 isoform f [H ( 278) 942 228.4 1.1e-59
NP_001253985 (OMIM: 601761) caspase-7 isoform alph ( 303) 942 228.5 1.2e-59
NP_001218 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 942 228.5 1.2e-59
NP_203125 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 942 228.5 1.2e-59
XP_016872253 (OMIM: 601761) PREDICTED: caspase-7 i ( 311) 942 228.5 1.2e-59
NP_001307840 (OMIM: 601761) caspase-7 isoform g [H ( 311) 942 228.5 1.2e-59
XP_006718080 (OMIM: 601761) PREDICTED: caspase-7 i ( 317) 942 228.5 1.2e-59
XP_016872252 (OMIM: 601761) PREDICTED: caspase-7 i ( 322) 942 228.5 1.3e-59
NP_203124 (OMIM: 601761) caspase-7 isoform delta [ ( 336) 942 228.5 1.3e-59
NP_001253986 (OMIM: 601761) caspase-7 isoform e [H ( 388) 942 228.5 1.5e-59
XP_006712859 (OMIM: 601762,603909,605027,613659) P ( 272) 461 116.3 6.3e-26
NP_001221 (OMIM: 601762,603909,605027,613659) casp ( 479) 461 116.4 1e-25
XP_005246964 (OMIM: 601762,603909,605027,613659) P ( 521) 461 116.4 1.1e-25
NP_116759 (OMIM: 601762,603909,605027,613659) casp ( 522) 461 116.4 1.1e-25
NP_001193471 (OMIM: 601762,603909,605027,613659) c ( 478) 428 108.7 2.1e-23
NP_116756 (OMIM: 601762,603909,605027,613659) casp ( 521) 428 108.8 2.2e-23
XP_005246951 (OMIM: 114480,114550,211980,601763,60 ( 280) 409 104.2 2.9e-22
XP_011510271 (OMIM: 114480,114550,211980,601763,60 ( 334) 403 102.8 8.8e-22
NP_001073593 (OMIM: 114480,114550,211980,601763,60 ( 464) 403 102.9 1.2e-21
XP_005246949 (OMIM: 114480,114550,211980,601763,60 ( 464) 403 102.9 1.2e-21
NP_203520 (OMIM: 114480,114550,211980,601763,60727 ( 464) 403 102.9 1.2e-21
XP_005246944 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_005246947 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_005246946 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_005246948 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_005246943 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_006712853 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_006712852 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
XP_005246945 (OMIM: 114480,114550,211980,601763,60 ( 479) 403 102.9 1.2e-21
NP_203519 (OMIM: 114480,114550,211980,601763,60727 ( 479) 403 102.9 1.2e-21
NP_001219 (OMIM: 114480,114550,211980,601763,60727 ( 496) 403 102.9 1.2e-21
XP_005246942 (OMIM: 114480,114550,211980,601763,60 ( 523) 403 102.9 1.3e-21
NP_001073594 (OMIM: 114480,114550,211980,601763,60 ( 538) 403 102.9 1.3e-21
NP_127463 (OMIM: 602234) caspase-9 isoform 3 [Homo ( 333) 392 100.3 5.2e-21
XP_005246071 (OMIM: 602234) PREDICTED: caspase-9 i ( 333) 392 100.3 5.2e-21
NP_001220 (OMIM: 602234) caspase-9 isoform alpha p ( 416) 392 100.3 6.2e-21
XP_011540575 (OMIM: 602234) PREDICTED: caspase-9 i ( 421) 392 100.3 6.3e-21
NP_001217 (OMIM: 601532) caspase-6 isoform alpha p ( 293) 386 98.8 1.2e-20
NP_001193453 (OMIM: 601762,603909,605027,613659) c ( 455) 368 94.7 3.3e-19
NP_036246 (OMIM: 605848) caspase-14 precursor [Hom ( 242) 356 91.8 1.3e-18
NP_116787 (OMIM: 601532) caspase-6 isoform beta [H ( 204) 322 83.8 2.8e-16
NP_203126 (OMIM: 601761) caspase-7 isoform beta [H ( 253) 295 77.6 2.6e-14
NP_001215 (OMIM: 600639) caspase-2 isoform 2 [Homo ( 312) 278 73.7 4.9e-13
XP_011526163 (OMIM: 605848) PREDICTED: caspase-14 ( 230) 259 69.2 8.2e-12
NP_001177945 (OMIM: 608633) inactive caspase-12 [H ( 341) 224 61.1 3.3e-09
NP_150636 (OMIM: 147678) caspase-1 isoform delta [ ( 263) 195 54.3 2.8e-07
>>NP_004337 (OMIM: 600636) caspase-3 preproprotein [Homo (277 aa)
initn: 1855 init1: 1855 opt: 1855 Z-score: 2342.8 bits: 441.3 E(85289): 9.3e-124
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277)
10 20 30 40 50 60
pF1KE1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
190 200 210 220 230 240
250 260 270
pF1KE1 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
:::::::::::::::::::::::::::::::::::::
NP_004 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
250 260 270
>>XP_011530603 (OMIM: 600636) PREDICTED: caspase-3 isofo (277 aa)
initn: 1855 init1: 1855 opt: 1855 Z-score: 2342.8 bits: 441.3 E(85289): 9.3e-124
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277)
10 20 30 40 50 60
pF1KE1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
190 200 210 220 230 240
250 260 270
pF1KE1 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
:::::::::::::::::::::::::::::::::::::
XP_011 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
250 260 270
>>NP_116786 (OMIM: 600636) caspase-3 preproprotein [Homo (277 aa)
initn: 1855 init1: 1855 opt: 1855 Z-score: 2342.8 bits: 441.3 E(85289): 9.3e-124
Smith-Waterman score: 1855; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277)
10 20 30 40 50 60
pF1KE1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
190 200 210 220 230 240
250 260 270
pF1KE1 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
:::::::::::::::::::::::::::::::::::::
NP_116 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
250 260 270
>>XP_011538562 (OMIM: 601761) PREDICTED: caspase-7 isofo (270 aa)
initn: 942 init1: 524 opt: 942 Z-score: 1192.6 bits: 228.4 E(85289): 1.1e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:27-268)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
XP_011 MFVSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
XP_011 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
XP_011 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
XP_011 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
180 190 200 210 220 230
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
XP_011 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
240 250 260 270
>>NP_001253987 (OMIM: 601761) caspase-7 isoform f [Homo (278 aa)
initn: 942 init1: 524 opt: 942 Z-score: 1192.4 bits: 228.4 E(85289): 1.1e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:35-276)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
NP_001 LFSDGDTSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
NP_001 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
NP_001 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
NP_001 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
190 200 210 220 230 240
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
NP_001 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
250 260 270
>>NP_001253985 (OMIM: 601761) caspase-7 isoform alpha pr (303 aa)
initn: 942 init1: 524 opt: 942 Z-score: 1191.8 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:60-301)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
NP_001 SFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
NP_001 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
NP_001 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
NP_001 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
210 220 230 240 250 260
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
NP_001 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
270 280 290 300
>>NP_001218 (OMIM: 601761) caspase-7 isoform alpha precu (303 aa)
initn: 942 init1: 524 opt: 942 Z-score: 1191.8 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:60-301)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
NP_001 SFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
NP_001 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
NP_001 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
NP_001 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
210 220 230 240 250 260
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
NP_001 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
270 280 290 300
>>NP_203125 (OMIM: 601761) caspase-7 isoform alpha precu (303 aa)
initn: 942 init1: 524 opt: 942 Z-score: 1191.8 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:60-301)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
NP_203 SFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
NP_203 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
NP_203 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
NP_203 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
210 220 230 240 250 260
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
NP_203 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
270 280 290 300
>>XP_016872253 (OMIM: 601761) PREDICTED: caspase-7 isofo (311 aa)
initn: 963 init1: 524 opt: 942 Z-score: 1191.7 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:68-309)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
XP_016 SGTLYFTSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
XP_016 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
XP_016 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
XP_016 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
220 230 240 250 260 270
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
XP_016 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
280 290 300 310
>>NP_001307840 (OMIM: 601761) caspase-7 isoform g [Homo (311 aa)
initn: 963 init1: 524 opt: 942 Z-score: 1191.7 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 942; 57.4% identity (79.8% similar) in 242 aa overlap (37-275:68-309)
10 20 30 40 50 60
pF1KE1 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG
:.:.. ..: ::::::::: : ::: :.:
NP_001 SGTLYFTSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI
:: :: : . ::.: ..: :: . .. .:.. .:.:::.. . :.:.:::::::..
NP_001 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE1 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG-VDDDMAC-
:.: .: . .: .: ::::::..: :::::.:::::::::: ::..::: ..: :
NP_001 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE1 -HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV
.:::::::::.::::.:::::::. ::::.:.::..:.... ::.:.:::::: .:
NP_001 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV
220 230 240 250 260 270
250 260 270
pF1KE1 ATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
: .::: : : :: ::::::.::::::::::
NP_001 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
280 290 300 310
277 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:08:09 2016 done: Mon Nov 7 01:08:10 2016
Total Scan time: 6.350 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]