Result of FASTA (omim) for
pFN21AE1433
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1433, 499 aa
1>>>pF1KE1433 499 - 499 aa - 499 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3469+/-0.000412; mu= 11.1622+/- 0.026
mean_var=223.4676+/-49.203, 0's: 0 Z-trim(118.3): 197 B-trim: 1506 in 1/55
Lambda= 0.085796
statistics sampled from 30833 (31116) to 30833 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.365), width: 16
Scan time: 10.680
The best scores are: opt bits E(85289)
NP_001246 (OMIM: 603618) cell division cycle prote ( 499) 3401 434.1 4.3e-121
XP_016882352 (OMIM: 603619) PREDICTED: fizzy-relat ( 528) 1096 148.9 3.4e-35
NP_001129670 (OMIM: 603619) fizzy-related protein ( 496) 1095 148.7 3.6e-35
XP_005259630 (OMIM: 603619) PREDICTED: fizzy-relat ( 496) 1095 148.7 3.6e-35
NP_057347 (OMIM: 603619) fizzy-related protein hom ( 493) 1094 148.6 3.9e-35
NP_001129669 (OMIM: 603619) fizzy-related protein ( 404) 876 121.5 4.6e-27
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 343 55.7 4e-07
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 343 55.7 4.2e-07
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 337 55.0 7.5e-07
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 337 55.0 7.5e-07
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 337 55.0 7.5e-07
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 337 55.0 7.5e-07
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 337 55.1 7.6e-07
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 337 55.1 7.6e-07
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 337 55.1 7.6e-07
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 337 55.1 7.7e-07
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 337 55.1 7.7e-07
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 337 55.1 7.7e-07
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 337 55.1 7.7e-07
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 334 54.5 8.4e-07
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 334 54.5 8.4e-07
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 334 54.5 8.4e-07
XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 334 54.6 8.6e-07
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 328 53.7 1.2e-06
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 328 53.8 1.4e-06
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 328 53.8 1.4e-06
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 328 53.8 1.4e-06
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 328 53.8 1.4e-06
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 328 53.8 1.4e-06
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 328 53.8 1.4e-06
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 328 53.8 1.4e-06
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 328 53.8 1.4e-06
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 328 53.8 1.4e-06
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 323 53.2 2.2e-06
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 323 53.2 2.2e-06
NP_001132940 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 322 53.1 2.4e-06
XP_011543873 (OMIM: 300196) PREDICTED: F-box-like/ ( 526) 322 53.1 2.4e-06
NP_001132939 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 322 53.1 2.4e-06
NP_001132938 (OMIM: 300196) F-box-like/WD repeat-c ( 577) 322 53.1 2.5e-06
NP_005638 (OMIM: 300196) F-box-like/WD repeat-cont ( 577) 322 53.1 2.5e-06
NP_008882 (OMIM: 601787) transcription initiation ( 800) 314 52.3 6.1e-06
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 294 49.3 1.8e-05
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 294 49.3 1.8e-05
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 261 46.0 0.00076
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 261 46.0 0.00077
NP_620640 (OMIM: 601787) transcription initiation ( 745) 255 45.0 0.00093
NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212) 245 43.1 0.00099
XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 245 43.2 0.0012
NP_079510 (OMIM: 609540) WD repeat-containing prot ( 305) 245 43.2 0.0012
XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-c ( 305) 245 43.2 0.0012
>>NP_001246 (OMIM: 603618) cell division cycle protein 2 (499 aa)
initn: 3401 init1: 3401 opt: 3401 Z-score: 2295.0 bits: 434.1 E(85289): 4.3e-121
Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KE1 MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARR
430 440 450 460 470 480
490
pF1KE1 REREKASAAKSSLIHQGIR
:::::::::::::::::::
NP_001 REREKASAAKSSLIHQGIR
490
>>XP_016882352 (OMIM: 603619) PREDICTED: fizzy-related p (528 aa)
initn: 1157 init1: 490 opt: 1096 Z-score: 752.8 bits: 148.9 E(85289): 3.4e-35
Smith-Waterman score: 1114; 40.5% identity (66.7% similar) in 472 aa overlap (58-487:61-519)
30 40 50 60 70 80
pF1KE1 WQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQ
:: .:: : ..::: : ::.:: :..:.
XP_016 LAMDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPV-SSPSKHG-DRFIPSRAGAN
40 50 60 70 80
90 100 110 120 130 140
pF1KE1 MEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFD-VEEAKILR--LSG----KPQNA
: .. :: ..:..... : : . :: : . . .:. : : : :.
XP_016 WSVNFHRIN-----ENEKSPSQNRKAKD-ATSDNGKDGLAYSALLKNELLGAGIEKVQD-
90 100 110 120 130 140
150 160
pF1KE1 PEGYQNRLK------------VLYSQKATPG----------------------SSRKTCR
:. . ::. : .....: : :: :
XP_016 PQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTR
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE1 YIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPG
: ..: ..:::::...:.::::::::: :::.:.: . :::::: .... .: .. :
XP_016 KISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEG
210 220 230 240 250 260
230 240 250 260 270 280
pF1KE1 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSR
. ..::.: ..:: .:::: .. ::.::. :.: . .:.::::.:.::. ::::::
XP_016 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE1 SGHIHHHDVRVAEHHVAT-LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW
. : ..:.:. . :.:: ::::::.:. : . :::::::: . :: ....
XP_016 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSL
330 340 350 360 370
350 360 370 380 390 400
pF1KE1 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSI
:.: .:.: .::::.:: : : ..::.::::.:: ::.::. .: :. .:. ::::..
XP_016 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL
380 390 400 410 420 430
410 420 430 440 450 460
pF1KE1 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE
:: : .::.: ::..:::...::::....::.: ::. ::: :.::::: .....:.::
XP_016 AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE
440 450 460 470 480 490
470 480 490
pF1KE1 TLRLWRCFELDPARRREREKASAAKSSLIHQGIR
:::.: : . . . :..:
XP_016 TLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
500 510 520
>>NP_001129670 (OMIM: 603619) fizzy-related protein homo (496 aa)
initn: 1157 init1: 490 opt: 1095 Z-score: 752.4 bits: 148.7 E(85289): 3.6e-35
Smith-Waterman score: 1114; 40.5% identity (66.7% similar) in 472 aa overlap (58-487:29-487)
30 40 50 60 70 80
pF1KE1 WQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQ
:: .:: : ..::: : ::.:: :..:.
NP_001 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPV-SSPSKHG-DRFIPSRAGAN
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 MEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFD-VEEAKILR--LSG----KPQNA
: .. :: ..:..... : : . :: : . . .:. : : : :.
NP_001 WSVNFHRIN-----ENEKSPSQNRKAKD-ATSDNGKDGLAYSALLKNELLGAGIEKVQD-
60 70 80 90 100
150 160
pF1KE1 PEGYQNRLK------------VLYSQKATPG----------------------SSRKTCR
:. . ::. : .....: : :: :
NP_001 PQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 YIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPG
: ..: ..:::::...:.::::::::: :::.:.: . :::::: .... .: .. :
NP_001 KISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEG
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSR
. ..::.: ..:: .:::: .. ::.::. :.: . .:.::::.:.::. ::::::
NP_001 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 SGHIHHHDVRVAEHHVAT-LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW
. : ..:.:. . :.:: ::::::.:. : . :::::::: . :: ....
NP_001 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE1 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSI
:.: .:.: .::::.:: : : ..::.::::.:: ::.::. .: :. .:. ::::..
NP_001 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE1 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE
:: : .::.: ::..:::...::::....::.: ::. ::: :.::::: .....:.::
NP_001 AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE
410 420 430 440 450 460
470 480 490
pF1KE1 TLRLWRCFELDPARRREREKASAAKSSLIHQGIR
:::.: : . . . :..:
NP_001 TLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
470 480 490
>>XP_005259630 (OMIM: 603619) PREDICTED: fizzy-related p (496 aa)
initn: 1157 init1: 490 opt: 1095 Z-score: 752.4 bits: 148.7 E(85289): 3.6e-35
Smith-Waterman score: 1114; 40.5% identity (66.7% similar) in 472 aa overlap (58-487:29-487)
30 40 50 60 70 80
pF1KE1 WQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQ
:: .:: : ..::: : ::.:: :..:.
XP_005 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPV-SSPSKHG-DRFIPSRAGAN
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 MEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFD-VEEAKILR--LSG----KPQNA
: .. :: ..:..... : : . :: : . . .:. : : : :.
XP_005 WSVNFHRIN-----ENEKSPSQNRKAKD-ATSDNGKDGLAYSALLKNELLGAGIEKVQD-
60 70 80 90 100
150 160
pF1KE1 PEGYQNRLK------------VLYSQKATPG----------------------SSRKTCR
:. . ::. : .....: : :: :
XP_005 PQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 YIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPG
: ..: ..:::::...:.::::::::: :::.:.: . :::::: .... .: .. :
XP_005 KISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEG
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSR
. ..::.: ..:: .:::: .. ::.::. :.: . .:.::::.:.::. ::::::
XP_005 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 SGHIHHHDVRVAEHHVAT-LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW
. : ..:.:. . :.:: ::::::.:. : . :::::::: . :: ....
XP_005 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE1 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSI
:.: .:.: .::::.:: : : ..::.::::.:: ::.::. .: :. .:. ::::..
XP_005 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE1 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE
:: : .::.: ::..:::...::::....::.: ::. ::: :.::::: .....:.::
XP_005 AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE
410 420 430 440 450 460
470 480 490
pF1KE1 TLRLWRCFELDPARRREREKASAAKSSLIHQGIR
:::.: : . . . :..:
XP_005 TLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
470 480 490
>>NP_057347 (OMIM: 603619) fizzy-related protein homolog (493 aa)
initn: 1157 init1: 490 opt: 1094 Z-score: 751.8 bits: 148.6 E(85289): 3.9e-35
Smith-Waterman score: 1113; 41.3% identity (67.2% similar) in 458 aa overlap (58-473:29-473)
30 40 50 60 70 80
pF1KE1 WQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQ
:: .:: : ..::: : ::.:: :..:.
NP_057 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPV-SSPSKHG-DRFIPSRAGAN
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 MEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFD-VEEAKILR--LSG----KPQNA
: .. :: ..:..... : : . :: : . . .:. : : : :.
NP_057 WSVNFHRIN-----ENEKSPSQNRKAKD-ATSDNGKDGLAYSALLKNELLGAGIEKVQD-
60 70 80 90 100
150 160
pF1KE1 PEGYQNRLK------------VLYSQKATPG----------------------SSRKTCR
:. . ::. : .....: : :: :
NP_057 PQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 YIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPG
: ..: ..:::::...:.::::::::: :::.:.: . :::::: .... .: .. :
NP_057 KISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEG
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSR
. ..::.: ..:: .:::: .. ::.::. :.: . .:.::::.:.::. ::::::
NP_057 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 SGHIHHHDVRVAEHHVAT-LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW
. : ..:.:. . :.:: ::::::.:. : . :::::::: . :: ....
NP_057 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE1 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSI
:.: .:.: .::::.:: : : ..::.::::.:: ::.::. .: :. .:. ::::..
NP_057 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE1 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE
:: : .::.: ::..:::...::::....::.: ::. ::: :.::::: .....:.::
NP_057 AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE
410 420 430 440 450 460
470 480 490
pF1KE1 TLRLWRCFELDPARRREREKASAAKSSLIHQGIR
:::.: :
NP_057 TLRFWNVFSKTRSTKESVSVLNLFTRIR
470 480 490
>>NP_001129669 (OMIM: 603619) fizzy-related protein homo (404 aa)
initn: 934 init1: 490 opt: 876 Z-score: 606.9 bits: 121.5 E(85289): 4.6e-27
Smith-Waterman score: 876; 47.5% identity (76.4% similar) in 259 aa overlap (216-473:130-384)
190 200 210 220 230 240
pF1KE1 YLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGT
. .: .. :. ..::.: ..:: .::::
NP_001 LGAGIEKVQDPQTEDRRLQPSTPEKKGLFTVTRLCDLSVEGDSVTSVGWSERGNLVAVGT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 SSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVAT-
.. ::.::. :.: . .:.::::.:.::. ::::::. : ..:.:. .
NP_001 HKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWC
:.:: ::::::.:. : . :::::::: . :: .... :.: .:.: .::::.::
NP_001 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSLSPVQQYTEHLAAVKAIAWS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 PWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQ
: : ..::.::::.:: ::.::. .: :. .:. ::::.. :: : .::.: ::..:::
NP_001 PHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQ
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 LVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRRERE
...::::....::.: ::. ::: :.::::: .....:.:::::.: :
NP_001 ILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVS
340 350 360 370 380 390
490
pF1KE1 KASAAKSSLIHQGIR
NP_001 VLNLFTRIR
400
>>XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/WD r (540 aa)
initn: 364 init1: 156 opt: 343 Z-score: 248.9 bits: 55.7 E(85289): 4e-07
Smith-Waterman score: 343; 26.9% identity (61.3% similar) in 305 aa overlap (177-470:231-522)
150 160 170 180 190 200
pF1KE1 RLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSS-GNVLAV-ALDN
:.: .. .. .::.: :..::. . :.
XP_016 STARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD---VTSLDWNSDGTLLAMGSYDG
210 220 230 240 250
210 220 230 240 250 260
pF1KE1 SVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNY-LAVGTSSAEVQLWDVQQQKRLRN
. .:. ... : : . : : .. : :.::: :..:.... . .::.. . ..
XP_016 FARIWTENGNLASTLGQHKGP---IFALKWNKKGNYVLSAGVDKTTI-IWDAHTGEAKQQ
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 MTSHSARVGSLSW-NSYILSSGSRSGHIHHHDVRVA-EHHVATLSGHSQEVCGLRWAPDG
. ::: . ...: :.. ..: : . :: :.. .: : :..::..:: ...: :.:
XP_016 FPFHSAPALDVDWQNNMTFASCSTDMCIHV--CRLGCDHPVKTFQGHTNEVNAIKWDPSG
320 330 340 350 360 370
330 340 350 360 370
pF1KE1 RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSN---VLATGGGTS
::: ..: ...: : .. ::. ... ..: : :: . ....
XP_016 MLLASCSDDMTLKIW-SMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASF
380 390 400 410 420 430
380 390 400 410 420 430
pF1KE1 DRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVA
: .:.:.: .:.: .. :.. : :. .:: : : :: .: .. . ::. . . :
XP_016 DSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASG-SF-DKYVHIWNTQSGSLVH
440 450 460 470 480
440 450 460 470 480 490
pF1KE1 ELKGHTSRVLSLTMSPDGATVASAAAD--ETLRLWRCFELDPARRREREKASAAKSSLIH
.: :. .. . . : :...:.: ..: .:
XP_016 SYQG-TGGIFEVCWNARGDKVGASASDGSDSLAVWISNVLASEPEEEKTKIEH
490 500 510 520 530 540
pF1KE1 QGIR
>>XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/WD r (577 aa)
initn: 364 init1: 156 opt: 343 Z-score: 248.6 bits: 55.7 E(85289): 4.2e-07
Smith-Waterman score: 343; 26.9% identity (61.3% similar) in 305 aa overlap (177-470:231-522)
150 160 170 180 190 200
pF1KE1 RLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSS-GNVLAV-ALDN
:.: .. .. .::.: :..::. . :.
XP_016 STARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD---VTSLDWNSDGTLLAMGSYDG
210 220 230 240 250
210 220 230 240 250 260
pF1KE1 SVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNY-LAVGTSSAEVQLWDVQQQKRLRN
. .:. ... : : . : : .. : :.::: :..:.... . .::.. . ..
XP_016 FARIWTENGNLASTLGQHKGP---IFALKWNKKGNYVLSAGVDKTTI-IWDAHTGEAKQQ
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 MTSHSARVGSLSW-NSYILSSGSRSGHIHHHDVRVA-EHHVATLSGHSQEVCGLRWAPDG
. ::: . ...: :.. ..: : . :: :.. .: : :..::..:: ...: :.:
XP_016 FPFHSAPALDVDWQNNMTFASCSTDMCIHV--CRLGCDHPVKTFQGHTNEVNAIKWDPSG
320 330 340 350 360 370
330 340 350 360 370
pF1KE1 RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSN---VLATGGGTS
::: ..: ...: : .. ::. ... ..: : :: . ....
XP_016 MLLASCSDDMTLKIW-SMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASF
380 390 400 410 420 430
380 390 400 410 420 430
pF1KE1 DRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVA
: .:.:.: .:.: .. :.. : :. .:: : : :: .: .. . ::. . . :
XP_016 DSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASG-SF-DKYVHIWNTQSGSLVH
440 450 460 470 480
440 450 460 470 480 490
pF1KE1 ELKGHTSRVLSLTMSPDGATVASAAAD--ETLRLWRCFELDPARRREREKASAAKSSLIH
.: :. .. . . : :...:.: ..: .:
XP_016 SYQG-TGGIFEVCWNARGDKVGASASDGSDSLAVWISNVLASEPEEEKTKIVSVHLFASL
490 500 510 520 530 540
pF1KE1 QGIR
XP_016 SSASENALSTHCTEFFMWQLWSKLQHSFHL
550 560 570
>>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea (655 aa)
initn: 368 init1: 113 opt: 337 Z-score: 244.0 bits: 55.0 E(85289): 7.5e-07
Smith-Waterman score: 337; 31.7% identity (63.9% similar) in 230 aa overlap (193-417:31-249)
170 180 190 200 210 220
pF1KE1 KTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNS-VYLWSASSGD-ILQLL
.:: .::.. :. : ::: .. . :..:
NP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT
10 20 30 40 50 60
230 240 250 260 270
pF1KE1 QMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSY-
.: . :: . ...:..:. ...::.. : ::.. .:.: . ::... :
NP_005 GHTSP---VESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG
70 80 90 100 110
280 290 300 310 320 330
pF1KE1 -ILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPS
...:::.. .:. :.: . : :::: : ::..:::. :::...:. :..:
NP_005 EFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL
120 130 140 150 160 170
340 350 360 370 380 390
pF1KE1 APGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDA
. :. .. : : : :..: . : . .::.: .::: ::.:.. . .: ...
NP_005 TAGK----MMSEFPGHTGPVNVVEFHP-NEYLLASG--SSDRTIRFWDLEKFQVVSCIEG
180 190 200 210 220
400 410 420 430 440 450
pF1KE1 H-SQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGAT
. . : :.:..: : ::
NP_005 EPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVA
230 240 250 260 270 280
>>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa)
initn: 368 init1: 113 opt: 337 Z-score: 244.0 bits: 55.0 E(85289): 7.5e-07
Smith-Waterman score: 337; 31.7% identity (63.9% similar) in 230 aa overlap (193-417:31-249)
170 180 190 200 210 220
pF1KE1 KTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNS-VYLWSASSGD-ILQLL
.:: .::.. :. : ::: .. . :..:
XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT
10 20 30 40 50 60
230 240 250 260 270
pF1KE1 QMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSY-
.: . :: . ...:..:. ...::.. : ::.. .:.: . ::... :
XP_016 GHTSP---VESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG
70 80 90 100 110
280 290 300 310 320 330
pF1KE1 -ILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPS
...:::.. .:. :.: . : :::: : ::..:::. :::...:. :..:
XP_016 EFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL
120 130 140 150 160 170
340 350 360 370 380 390
pF1KE1 APGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDA
. :. .. : : : :..: . : . .::.: .::: ::.:.. . .: ...
XP_016 TAGK----MMSEFPGHTGPVNVVEFHP-NEYLLASG--SSDRTIRFWDLEKFQVVSCIEG
180 190 200 210 220
400 410 420 430 440 450
pF1KE1 H-SQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGAT
. . : :.:..: : ::
XP_016 EPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVA
230 240 250 260 270 280
499 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:30:54 2016 done: Sun Nov 6 23:30:55 2016
Total Scan time: 10.680 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]