Result of FASTA (omim) for
pFN21AE1424
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1424, 556 aa
1>>>pF1KE1424 556 - 556 aa - 556 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3722+/-0.000561; mu= 17.9923+/- 0.035
mean_var=70.4658+/-14.266, 0's: 0 Z-trim(105.3): 36 B-trim: 0 in 0/51
Lambda= 0.152787
statistics sampled from 13458 (13491) to 13458 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.497), E-opt: 0.2 (0.158), width: 16
Scan time: 9.480
The best scores are: opt bits E(85289)
NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 3500 781.8 0
NP_001008897 (OMIM: 186980) T-complex protein 1 su ( 401) 2534 568.8 1.2e-161
NP_006420 (OMIM: 605140) T-complex protein 1 subun ( 543) 903 209.3 2.5e-53
NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 874 202.9 2.1e-51
NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 848 197.2 1.1e-49
NP_001293082 (OMIM: 256840,610150) T-complex prote ( 520) 844 196.3 2e-49
NP_036205 (OMIM: 256840,610150) T-complex protein ( 541) 842 195.9 2.8e-49
NP_001159757 (OMIM: 605140) T-complex protein 1 su ( 499) 838 195.0 4.8e-49
XP_011530781 (OMIM: 605140) PREDICTED: T-complex p ( 499) 838 195.0 4.8e-49
XP_011530780 (OMIM: 605140) PREDICTED: T-complex p ( 499) 838 195.0 4.8e-49
NP_001293085 (OMIM: 256840,610150) T-complex prote ( 503) 833 193.9 1e-48
NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 755 176.7 1.6e-43
NP_006575 (OMIM: 610730) T-complex protein 1 subun ( 530) 742 173.8 1.2e-42
NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 707 166.1 2.4e-40
XP_016879512 (OMIM: 610730) PREDICTED: T-complex p ( 464) 691 162.5 2.6e-39
NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 683 160.8 9.4e-39
NP_001159756 (OMIM: 605140) T-complex protein 1 su ( 456) 675 159.0 2.9e-38
NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 653 154.2 9.6e-37
NP_001293084 (OMIM: 256840,610150) T-complex prote ( 448) 598 142.0 3.7e-33
NP_001293083 (OMIM: 256840,610150) T-complex prote ( 486) 598 142.1 4e-33
NP_001009186 (OMIM: 104613) T-complex protein 1 su ( 486) 578 137.7 8.4e-32
NP_001009570 (OMIM: 605140) T-complex protein 1 su ( 339) 572 136.2 1.6e-31
NP_001180459 (OMIM: 610730) T-complex protein 1 su ( 485) 573 136.5 1.8e-31
NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 564 134.6 7.2e-31
XP_011522505 (OMIM: 610730) PREDICTED: T-complex p ( 388) 519 124.6 5.8e-28
XP_016879513 (OMIM: 610730) PREDICTED: T-complex p ( 351) 395 97.2 9e-20
NP_001180458 (OMIM: 610730) T-complex protein 1 su ( 493) 386 95.3 4.7e-19
NP_955472 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 195 53.3 2.5e-06
NP_002147 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 195 53.3 2.5e-06
NP_078961 (OMIM: 610148,615987) Bardet-Biedl syndr ( 723) 149 43.2 0.0034
>>NP_110379 (OMIM: 186980) T-complex protein 1 subunit a (556 aa)
initn: 3500 init1: 3500 opt: 3500 Z-score: 4171.9 bits: 781.8 E(85289): 0
Smith-Waterman score: 3500; 100.0% identity (100.0% similar) in 556 aa overlap (1-556:1-556)
10 20 30 40 50 60
pF1KE1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD
490 500 510 520 530 540
550
pF1KE1 KHGSYEDAVHSGALND
::::::::::::::::
NP_110 KHGSYEDAVHSGALND
550
>>NP_001008897 (OMIM: 186980) T-complex protein 1 subuni (401 aa)
initn: 2534 init1: 2534 opt: 2534 Z-score: 3023.3 bits: 568.8 E(85289): 1.2e-161
Smith-Waterman score: 2534; 100.0% identity (100.0% similar) in 401 aa overlap (156-556:1-401)
130 140 150 160 170 180
pF1KE1 KEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIR
::::::::::::::::::::::::::::::
NP_001 MSSKIIGINGDFFANMVVDAVLAIKYTDIR
10 20 30
190 200 210 220 230 240
pF1KE1 GQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTK
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 MKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE1 MAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIK
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE1 NTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLEN
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE1 YATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKW
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE1 IGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSY
340 350 360 370 380 390
550
pF1KE1 EDAVHSGALND
:::::::::::
NP_001 EDAVHSGALND
400
>>NP_006420 (OMIM: 605140) T-complex protein 1 subunit e (543 aa)
initn: 991 init1: 377 opt: 903 Z-score: 1078.4 bits: 209.3 E(85289): 2.5e-53
Smith-Waterman score: 1015; 36.8% identity (65.6% similar) in 538 aa overlap (10-540:14-528)
10 20 30 40 50
pF1KE1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITN
: : : .:. : ::. :...::: :.::..:: : .::.:
NP_006 MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTS
:::::::::.: :::::.: ..: :: :::::::::...:::.::.. :.. .::
NP_006 DGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 VISGYRLACKEAVRYINENLIV--NTDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVV
.: ..: : . :: :.: .. ..:.. : : . : :..:::.:. . :::.:::
NP_006 IIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 DAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALN---CVVGSQGMPKRIV
:::. . :. .. ..: :..: . .:.:..: :.. .: . .::.
NP_006 DAVMMLD--DL-----LQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYH
190 200 210 220 230
240 250 260 270 280 290
pF1KE1 NAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTG
: ::: :. :. : .... . : . : . : .: ....:: .::.:.:.
NP_006 NPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 GIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEE
: :. .::.. . . :: ..:::: : :..: ... : : .::. .
NP_006 PIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNAL------SADVLGRCQV
300 310 320 330 340
360 370 380 390 400
pF1KE1 VVQERICDDELILIKNT-KARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVV
. .: .. .. . ::.: . :. ::..:: .: :::::::. .:.:.... :::
NP_006 FEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFM-EETERSLHDAIMIVRRAIKNDSVV
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE1 PGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRA
::::.: :: ::..:. .. ...:: :. .:..: .:: : ::. :.:... ::::
NP_006 AGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRA
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE1 FHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDD
: .. . : :.:..: :: .: :.::..:....: :.::: :. .:.
NP_006 RHAQGGT--------WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDE
470 480 490 500 510
530 540 550
pF1KE1 LIKLHPESKDDKHGSYEDAVHSGALND
:: .:.: :
NP_006 TIK-NPRSTVDAPTAAGRGRGRGRPH
520 530 540
>>NP_006421 (OMIM: 605142) T-complex protein 1 subunit d (539 aa)
initn: 695 init1: 395 opt: 874 Z-score: 1043.9 bits: 202.9 E(85289): 2.1e-51
Smith-Waterman score: 943; 33.0% identity (66.0% similar) in 533 aa overlap (8-531:24-536)
10 20 30 40
pF1KE1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKM
. ::. :: .:. :: ..:. ...:::: :.:::
NP_006 MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNA
. : :::::::::::::: ..: ::::..: ::. :: :.:::::::::::. :: .
NP_006 IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 DELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELG-RDCLINAAKTSMSSKIIGI
.:... :::: . ... : ..... ... . ::. :. :.:.: ::..::...
NP_006 TKLLQKGIHPTIISESFQKALEKGIEILTD--MSRPVELSDRETLLNSATTSLNSKVVSQ
130 140 150 160 170
170 180 190 200 210 220
pF1KE1 NGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQ
..... : :.::. : : . ...:.: : . . :. : .:. :...
NP_006 YSSLLSPMSVNAVM--KVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 GMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGA
:. :. .:::. ..: :. : . :.:..: ..:.. ..: . ...: ::
NP_006 GIT-RVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGC
240 250 260 270 280 290
290 300 310 320 330
pF1KE1 NVILTTGGI-----DDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEE
::.: .: .:. :... . :... . ..:.. : :. :. . .:...
NP_006 NVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGT---KPVAHID---
300 310 320 330 340
340 350 360 370 380 390
pF1KE1 TFEAAMLGQAEEVVQERICDDELILIKNTKART---SASIILRGANDFMCDEMERSLHDA
: : :::.:: ...: . :.: : . ...:..::.: .. .: :::.:::
NP_006 QFTADMLGSAE-LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDA
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE1 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN
:::.. ........ :::: : :.. : .:. .... :. . :: .. :::.::: :
NP_006 LCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAEN
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE1 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK
:. . . :..:: : ... : :... .: . . : .: .:.:..:
NP_006 AGLNPISTVTELRNRHAQGE--------KTAGINVRKGGISNILEELVVQPLLVSVSALT
470 480 490 500 510 520
520 530 540 550
pF1KE1 FATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND
.:::.. .::.:::..
NP_006 LATETVRSILKIDDVVNTR
530
>>NP_005989 (OMIM: 600114) T-complex protein 1 subunit g (545 aa)
initn: 844 init1: 393 opt: 848 Z-score: 1012.8 bits: 197.2 E(85289): 1.1e-49
Smith-Waterman score: 981; 34.0% identity (65.1% similar) in 541 aa overlap (11-548:16-542)
10 20 30 40 50
pF1KE1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTIT
: .:. ..: :. :: .::.:... ::: .. :::.: .: ...:
NP_005 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 NDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPT
::: .::. ..:.::::: . :.. ::.:::::::::.:.:.:.:. :.....:..:::
NP_005 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 SVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDA
:::.:: : . . . ... . .: : ..: ..:...: :. ... :...::
NP_005 VVISAYRKALDDMISTL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDA
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 VLAIKYTDIRGQPRYPVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKI
: ... . :. . ... . . : : .: .. : .: : : . : : .:
NP_005 VKMVQFEE-NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDD
. :: ::. : . ... :: : . .: : : . .. . :. .:..: ::.:
NP_005 VLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 MCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQE
. .:...:. :.::: : : .:::.: :: :.: .:. ... .: : . .
NP_005 LAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK-----
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 RICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGA
.: :. . .: . : . .:.::::. . .:.::.:.::. : . :: . ..::::::
NP_005 KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE1 VEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEA
: :.. : . . .: . :: :..: ::: :: : . .. :...::: : .
NP_005 SEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKH--T
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE1 QVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLH
: : : : :.. .: : :. :..:: ::... : :.:.:. .:::::... :
NP_005 QENCET----W-GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGH
480 490 500 510 520
540 550
pF1KE1 PESKDD--KHGSYEDAVHSGALND
.. :: ..:. ::
NP_005 KKKGDDQSRQGGAPDAGQE
530 540
>>NP_001293082 (OMIM: 256840,610150) T-complex protein 1 (520 aa)
initn: 912 init1: 403 opt: 844 Z-score: 1008.4 bits: 196.3 E(85289): 2e-49
Smith-Waterman score: 909; 33.3% identity (67.5% similar) in 532 aa overlap (10-532:2-514)
10 20 30 40 50
pF1KE1 MEGPLSVFGDRSTGETIRS---QNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITND
. : : ::.. ...::: ..:: ...:::: :::::.:: ::::.:::
NP_001 MNSSLGPTIEKLSVSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTND
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 GATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSV
:::::....:.: ::.. ::. :: :.:::::.::..:. ::..:..:. . ::: .
NP_001 GATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 ISGYRLACKEAVRY---INENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVD
.::. : . :... :.....:. . . ::..:::...::... .:...:.
NP_001 ADGYEQAARVAIEHLDKISDSVLVDIKDT--EPLIQTAKTTLGSKVVNSCHRQMAEIAVN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 AVLAIKYTDIRGQPRYPVNSVNILKAHGR--SQME-SMLISGYALNCVVGSQGMPKRIVN
:::.. .:.. : :. ...:..:. ...: . ::.: .. . :::.. .
NP_001 AVLTV--ADME---RRDVD-FELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVED
180 190 200 210 220
240 250 260 270 280 290
pF1KE1 AKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGG
:::: : .. : : .. .:. : ... :.. .: ::.: ::::. . :
NP_001 AKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 IDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEV
.:: . ... . ::: : ... :: :.:. :. ...: .:. .. : ..:.
NP_001 FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKL---GFAGLVQEI
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 VQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPG
. :....:.. : ...:..::.: .. .: .:::::::::.. ..... :: :
NP_001 -SFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYG
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 GGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFH
:::.: . .. . . : . . :: :. :: .: ::: .:. :.... . ....:: .
NP_001 GGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQ
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE1 NEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI
. ..:: .:.: . : :: :.: : : .....::. . ::.:::.
NP_001 VK-EMNPA------LGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIR
470 480 490 500 510
540 550
pF1KE1 KLHPESKDDKHGSYEDAVHSGALND
:
NP_001 KPGESEE
520
>>NP_036205 (OMIM: 256840,610150) T-complex protein 1 su (541 aa)
initn: 907 init1: 398 opt: 842 Z-score: 1005.7 bits: 195.9 E(85289): 2.8e-49
Smith-Waterman score: 907; 33.6% identity (67.7% similar) in 524 aa overlap (15-532:32-535)
10 20 30 40
pF1KE1 MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKM
:...:. .::: ..:: ...:::: :::::
NP_036 ASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSH-IMAAKAVANTMRTSLGPNGLDKM
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNA
.:: ::::.::::::::....:.: ::.. ::. :: :.:::::.::..:. ::..:
NP_036 MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 DELVKQKIHPTSVISGYRLACKEAVRY---INENLIVNTDELGRDCLINAAKTSMSSKII
..:. . ::: . .::. : . :... :.....:. . . ::..:::...::..
NP_036 EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDT--EPLIQTAKTTLGSKVV
130 140 150 160 170
170 180 190 200 210
pF1KE1 GINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGR--SQME-SMLISGYALNC
. .:...:.:::.. .:.. : :. ...:..:. ...: . ::.: ..
NP_036 NSCHRQMAEIAVNAVLTV--ADME---RRDVD-FELIKVEGKVGGRLEDTKLIKGVIVDK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 VVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKI
. :::.. .:::: : .. : : .. .:. : ... :.. .: ::.:
NP_036 DFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQI
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 LATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEE
::::. . :.:: . ... . ::: : ... :: :.:. :. ...: .:.
NP_036 KETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEK
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE1 TFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCV
: : ..:. . :....:.. : ...:..::.: .. .: .:::::::::
NP_036 LGFA---GLVQEI-SFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCV
360 370 380 390 400
400 410 420 430 440 450
pF1KE1 VKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQ
.. ..... :: ::::.: . .. . . : . . :: :. :: .: ::: .:. :...
NP_036 IRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGM
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE1 DSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFAT
. . ....:: .. ..:: .:.: . : :: :.: : : .....::
NP_036 NPIQTMTEVRA-RQVKEMNPA------LGIDCLHKGTNDMKQQHVIETLIGKKQQISLAT
470 480 490 500 510 520
520 530 540 550
pF1KE1 EAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND
. . ::.:::. :
NP_036 QMVRMILKIDDIRKPGESEE
530 540
>>NP_001159757 (OMIM: 605140) T-complex protein 1 subuni (499 aa)
initn: 932 init1: 318 opt: 838 Z-score: 1001.5 bits: 195.0 E(85289): 4.8e-49
Smith-Waterman score: 950; 36.7% identity (66.1% similar) in 507 aa overlap (41-540:1-484)
20 30 40 50 60 70
pF1KE1 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP
.::..:: : .::.::::::::::.: ::
NP_001 MDKLIVDGRGKATISNDGATILKLLDVVHP
10 20 30
80 90 100 110 120 130
pF1KE1 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR
:::.: ..: :: :::::::::...:::.::.. :.. .:: .: ..: : . ::
NP_001 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN
40 50 60 70 80 90
140 150 160 170 180
pF1KE1 YINENLIV--NTDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ
:.: .. ..:.. : : . : :..:::.:. . :::.::::::. . :.
NP_001 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLD--DL---
100 110 120 130 140
190 200 210 220 230 240
pF1KE1 PRYPVNSVNILKAHGRSQMESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQKT
.. ..: :..: . .:.:..: :.. .: . .::. : ::: :. :.
NP_001 --LQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 KMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAG
: .... . : . : . : .: ....:: .::.:.:. : :. .::..
NP_001 AEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRD
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 AMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILI
. . :: ..:::: : :..: ... : : .::. . . .: .. ..
NP_001 MFCAGRVPEEDLKRTMMACGGSIQTSVNALS------ADVLGRCQVFEETQIGGERYNFF
270 280 290 300 310
370 380 390 400 410 420
pF1KE1 KNT-KARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL
. ::.: . :. ::..:: .: :::::::. .:.:.... ::: ::::.: :: ::
NP_001 TGCPKAKTCTFILRGGAEQFM-EETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL
..:. .. ...:: :. .:..: .:: : ::. :.:... :::: : .. .
NP_001 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT-------
380 390 400 410 420
490 500 510 520 530 540
pF1KE1 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHG
: :.:..: :: .: :.::..:....: :.::: :. .:. :: .:.: :
NP_001 -WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVDAPT
430 440 450 460 470 480
550
pF1KE1 SYEDAVHSGALND
NP_001 AAGRGRGRGRPH
490
>>XP_011530781 (OMIM: 605140) PREDICTED: T-complex prote (499 aa)
initn: 932 init1: 318 opt: 838 Z-score: 1001.5 bits: 195.0 E(85289): 4.8e-49
Smith-Waterman score: 950; 36.7% identity (66.1% similar) in 507 aa overlap (41-540:1-484)
20 30 40 50 60 70
pF1KE1 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP
.::..:: : .::.::::::::::.: ::
XP_011 MDKLIVDGRGKATISNDGATILKLLDVVHP
10 20 30
80 90 100 110 120 130
pF1KE1 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR
:::.: ..: :: :::::::::...:::.::.. :.. .:: .: ..: : . ::
XP_011 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN
40 50 60 70 80 90
140 150 160 170 180
pF1KE1 YINENLIV--NTDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ
:.: .. ..:.. : : . : :..:::.:. . :::.::::::. . :.
XP_011 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLD--DL---
100 110 120 130 140
190 200 210 220 230 240
pF1KE1 PRYPVNSVNILKAHGRSQMESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQKT
.. ..: :..: . .:.:..: :.. .: . .::. : ::: :. :.
XP_011 --LQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 KMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAG
: .... . : . : . : .: ....:: .::.:.:. : :. .::..
XP_011 AEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRD
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 AMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILI
. . :: ..:::: : :..: ... : : .::. . . .: .. ..
XP_011 MFCAGRVPEEDLKRTMMACGGSIQTSVNALS------ADVLGRCQVFEETQIGGERYNFF
270 280 290 300 310
370 380 390 400 410 420
pF1KE1 KNT-KARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL
. ::.: . :. ::..:: .: :::::::. .:.:.... ::: ::::.: :: ::
XP_011 TGCPKAKTCTFILRGGAEQFM-EETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL
..:. .. ...:: :. .:..: .:: : ::. :.:... :::: : .. .
XP_011 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT-------
380 390 400 410 420
490 500 510 520 530 540
pF1KE1 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHG
: :.:..: :: .: :.::..:....: :.::: :. .:. :: .:.: :
XP_011 -WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVDAPT
430 440 450 460 470 480
550
pF1KE1 SYEDAVHSGALND
XP_011 AAGRGRGRGRPH
490
>>XP_011530780 (OMIM: 605140) PREDICTED: T-complex prote (499 aa)
initn: 932 init1: 318 opt: 838 Z-score: 1001.5 bits: 195.0 E(85289): 4.8e-49
Smith-Waterman score: 950; 36.7% identity (66.1% similar) in 507 aa overlap (41-540:1-484)
20 30 40 50 60 70
pF1KE1 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP
.::..:: : .::.::::::::::.: ::
XP_011 MDKLIVDGRGKATISNDGATILKLLDVVHP
10 20 30
80 90 100 110 120 130
pF1KE1 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR
:::.: ..: :: :::::::::...:::.::.. :.. .:: .: ..: : . ::
XP_011 AAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVN
40 50 60 70 80 90
140 150 160 170 180
pF1KE1 YINENLIV--NTDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ
:.: .. ..:.. : : . : :..:::.:. . :::.::::::. . :.
XP_011 KIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLD--DL---
100 110 120 130 140
190 200 210 220 230 240
pF1KE1 PRYPVNSVNILKAHGRSQMESMLISGYALN---CVVGSQGMPKRIVNAKIACLDFSLQKT
.. ..: :..: . .:.:..: :.. .: . .::. : ::: :. :.
XP_011 --LQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 KMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAG
: .... . : . : . : .: ....:: .::.:.:. : :. .::..
XP_011 AEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRD
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 AMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILI
. . :: ..:::: : :..: ... : : .::. . . .: .. ..
XP_011 MFCAGRVPEEDLKRTMMACGGSIQTSVNALS------ADVLGRCQVFEETQIGGERYNFF
270 280 290 300 310
370 380 390 400 410 420
pF1KE1 KNT-KARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL
. ::.: . :. ::..:: .: :::::::. .:.:.... ::: ::::.: :: ::
XP_011 TGCPKAKTCTFILRGGAEQFM-EETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 ENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNL
..:. .. ...:: :. .:..: .:: : ::. :.:... :::: : .. .
XP_011 RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT-------
380 390 400 410 420
490 500 510 520 530 540
pF1KE1 KWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHG
: :.:..: :: .: :.::..:....: :.::: :. .:. :: .:.: :
XP_011 -WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK-NPRSTVDAPT
430 440 450 460 470 480
550
pF1KE1 SYEDAVHSGALND
XP_011 AAGRGRGRGRPH
490
556 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:36:14 2016 done: Mon Nov 7 15:36:16 2016
Total Scan time: 9.480 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]