Result of FASTA (omim) for
pFN21AE1422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1422, 425 aa
1>>>pF1KE1422 425 - 425 aa - 425 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0237+/-0.000373; mu= 6.7423+/- 0.024
mean_var=180.8963+/-35.265, 0's: 0 Z-trim(118.8): 9 B-trim: 0 in 0/54
Lambda= 0.095358
statistics sampled from 32197 (32206) to 32197 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.378), width: 16
Scan time: 8.330
The best scores are: opt bits E(85289)
NP_004648 (OMIM: 606728) serum deprivation-respons ( 425) 2664 378.6 1.7e-104
NP_036364 (OMIM: 603198,613327) polymerase I and t ( 390) 647 101.1 5.3e-21
XP_005257299 (OMIM: 603198,613327) PREDICTED: poly ( 225) 425 70.3 5.4e-12
>>NP_004648 (OMIM: 606728) serum deprivation-response pr (425 aa)
initn: 2664 init1: 2664 opt: 2664 Z-score: 1997.2 bits: 378.6 E(85289): 1.7e-104
Smith-Waterman score: 2664; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425)
10 20 30 40 50 60
pF1KE1 MGEDAAQAEKFQHPGSDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGEDAAQAEKFQHPGSDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KVREGESHAENETKSEDLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KVREGESHAENETKSEDLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQ
370 380 390 400 410 420
pF1KE1 VHQTS
:::::
NP_004 VHQTS
>>NP_036364 (OMIM: 603198,613327) polymerase I and trans (390 aa)
initn: 680 init1: 418 opt: 647 Z-score: 498.0 bits: 101.1 E(85289): 5.3e-21
Smith-Waterman score: 703; 38.5% identity (67.5% similar) in 382 aa overlap (14-355:14-379)
10 20 30 40 50
pF1KE1 MGEDAAQAEKFQHPG-SDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVL
:: : . .::: . . . :: . ..:: :... :::.: ::
NP_036 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGA----GSEELIKSD-QVNGVLVL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSR
.::::... .: .: .: ..:.:: .::.:..::..:.::.: .:.::::::::::: :
NP_036 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 KVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPV--S
:::.....:. ..:: .:.:.:: :.:.:::: .:::.:.:.: ..::.. ... . :
NP_036 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 GAVEGKE-ELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSL
:. :: : :.. :: ...:::: ::.: .:: .::::::.::::.:
NP_036 EALPEKEGEELGEGERPEEDAAALELSSD-------EAVE--VEEVIEESRAERIKRSGL
180 190 200 210 220
240 250 260
pF1KE1 KKVDSLKKAFS-----------------------------RQNIEKKMNKLGTKIVSVER
..::..::::: :...::.::::::..: .::
NP_036 RRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE1 REKIK-------KSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPS
:::.: ::.: .: . .:.. .:: :.:: ::.:::. .. . :. .. .
NP_036 REKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGA
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE1 SEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTIVEDE
... . .. :. .. . . ::. ::.::.
NP_036 DDDEGGAERGEAGDLRRGSSPDVHALL--EITEESDAVLVDKSDSD
350 360 370 380 390
390 400 410 420
pF1KE1 EEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQVHQTS
>>XP_005257299 (OMIM: 603198,613327) PREDICTED: polymera (225 aa)
initn: 416 init1: 393 opt: 425 Z-score: 336.3 bits: 70.3 E(85289): 5.4e-12
Smith-Waterman score: 425; 44.2% identity (76.1% similar) in 163 aa overlap (14-175:14-171)
10 20 30 40 50
pF1KE1 MGEDAAQAEKFQHPG-SDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVL
:: : . .::: . . . :: . ..:: :... :::.: ::
XP_005 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGA----GSEELIKSD-QVNGVLVL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSR
.::::... .: .: .: ..:.:: .::.:..::..:.::.: .:.::::::::::: :
XP_005 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 KVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGA
:::.....:. ..:: .:.:.:: :.:.:::: .:::.:.: ... : . :
XP_005 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQPKKKPNAPSDLATPKIVP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 VEGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKV
XP_005 FDLPETEPFDLKPETVPELPPFDQTPRALPYYPEPGPRPTPEELTAGGSV
180 190 200 210 220
425 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:11:27 2016 done: Mon Nov 7 01:11:28 2016
Total Scan time: 8.330 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]