Result of FASTA (omim) for
pFN21AE1410
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1410, 113 aa
1>>>pF1KE1410 113 - 113 aa - 113 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3240+/-0.000298; mu= 10.8572+/- 0.018
mean_var=100.6681+/-20.642, 0's: 0 Z-trim(119.6): 93 B-trim: 315 in 1/55
Lambda= 0.127829
statistics sampled from 33590 (33781) to 33590 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.396), width: 16
Scan time: 4.460
The best scores are: opt bits E(85289)
NP_055060 (OMIM: 603863) RING-box protein 2 isofor ( 113) 850 165.9 1.2e-41
NP_001188299 (OMIM: 603863) RING-box protein 2 iso ( 97) 439 90.1 7.3e-19
NP_899060 (OMIM: 603863) RING-box protein 2 isofor ( 90) 411 84.9 2.5e-17
NP_055063 (OMIM: 603814) E3 ubiquitin-protein liga ( 108) 392 81.4 3.2e-16
NP_001002246 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001002249 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001276345 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_057560 (OMIM: 614534) anaphase-promoting comple ( 84) 256 56.2 9.5e-09
NP_001002248 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001002247 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001002245 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001276343 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001276346 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
NP_001276344 (OMIM: 614534) anaphase-promoting com ( 84) 256 56.2 9.5e-09
>>NP_055060 (OMIM: 603863) RING-box protein 2 isoform 1 (113 aa)
initn: 850 init1: 850 opt: 850 Z-score: 868.5 bits: 165.9 E(85289): 1.2e-41
Smith-Waterman score: 850; 100.0% identity (100.0% similar) in 113 aa overlap (1-113:1-113)
10 20 30 40 50 60
pF1KE1 MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDA
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 CLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
70 80 90 100 110
>>NP_001188299 (OMIM: 603863) RING-box protein 2 isoform (97 aa)
initn: 422 init1: 412 opt: 439 Z-score: 459.7 bits: 90.1 E(85289): 7.3e-19
Smith-Waterman score: 687; 85.8% identity (85.8% similar) in 113 aa overlap (1-113:1-97)
10 20 30 40 50 60
pF1KE1 MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVM--
10 20 30 40 50
70 80 90 100 110
pF1KE1 CLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
:::::::::::::::::::::::::::::::::::::::
NP_001 --------------VVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
60 70 80 90
>>NP_899060 (OMIM: 603863) RING-box protein 2 isoform 3 (90 aa)
initn: 432 init1: 401 opt: 411 Z-score: 432.2 bits: 84.9 E(85289): 2.5e-17
Smith-Waterman score: 411; 79.3% identity (86.6% similar) in 82 aa overlap (1-79:1-76)
10 20 30 40 50
pF1KE1 MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQ--VM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.
NP_899 MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQMPVL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DACLRCQAENKQEDCVVVW-GECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
:. :. ::. .:.: ::
NP_899 DVKLKT---NKR---TVLWSGENVIIPSTTAACPCG
70 80 90
>>NP_055063 (OMIM: 603814) E3 ubiquitin-protein ligase R (108 aa)
initn: 392 init1: 220 opt: 392 Z-score: 412.3 bits: 81.4 E(85289): 3.2e-16
Smith-Waterman score: 392; 50.5% identity (76.3% similar) in 97 aa overlap (20-112:11-107)
10 20 30 40 50
pF1KE1 MADVEDGEETCALASHSGSSGSKSG-GDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMD
::..:: : : : .:::::::.:.::. :.::::: ..::
NP_055 MAAAMDVDTPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMD
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 ACLRCQAENKQ---EDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
:..:::.. . :.:.:.:: :::.:: :.: :.: . ::: ...: :. :
NP_055 LCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
60 70 80 90 100
>>NP_001002246 (OMIM: 614534) anaphase-promoting complex (84 aa)
initn: 219 init1: 92 opt: 256 Z-score: 278.0 bits: 56.2 E(85289): 9.5e-09
Smith-Waterman score: 256; 37.2% identity (67.9% similar) in 78 aa overlap (32-106:5-80)
10 20 30 40 50 60
pF1KE1 ADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDAC
.: ::.:: : : .. ..:.:::. :
NP_001 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCC
10 20 30
70 80 90 100 110
pF1KE1 LRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNN---RCPLCQQDWVVQRIGK
:.. . .:: .:::.:.: :: :. :.. .. .::.:.:.:
NP_001 PDCKVPG--DDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE
40 50 60 70 80
>>NP_001002249 (OMIM: 614534) anaphase-promoting complex (84 aa)
initn: 219 init1: 92 opt: 256 Z-score: 278.0 bits: 56.2 E(85289): 9.5e-09
Smith-Waterman score: 256; 37.2% identity (67.9% similar) in 78 aa overlap (32-106:5-80)
10 20 30 40 50 60
pF1KE1 ADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDAC
.: ::.:: : : .. ..:.:::. :
NP_001 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCC
10 20 30
70 80 90 100 110
pF1KE1 LRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNN---RCPLCQQDWVVQRIGK
:.. . .:: .:::.:.: :: :. :.. .. .::.:.:.:
NP_001 PDCKVPG--DDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE
40 50 60 70 80
>>NP_001276345 (OMIM: 614534) anaphase-promoting complex (84 aa)
initn: 219 init1: 92 opt: 256 Z-score: 278.0 bits: 56.2 E(85289): 9.5e-09
Smith-Waterman score: 256; 37.2% identity (67.9% similar) in 78 aa overlap (32-106:5-80)
10 20 30 40 50 60
pF1KE1 ADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDAC
.: ::.:: : : .. ..:.:::. :
NP_001 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCC
10 20 30
70 80 90 100 110
pF1KE1 LRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNN---RCPLCQQDWVVQRIGK
:.. . .:: .:::.:.: :: :. :.. .. .::.:.:.:
NP_001 PDCKVPG--DDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE
40 50 60 70 80
>>NP_057560 (OMIM: 614534) anaphase-promoting complex su (84 aa)
initn: 219 init1: 92 opt: 256 Z-score: 278.0 bits: 56.2 E(85289): 9.5e-09
Smith-Waterman score: 256; 37.2% identity (67.9% similar) in 78 aa overlap (32-106:5-80)
10 20 30 40 50 60
pF1KE1 ADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDAC
.: ::.:: : : .. ..:.:::. :
NP_057 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCC
10 20 30
70 80 90 100 110
pF1KE1 LRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNN---RCPLCQQDWVVQRIGK
:.. . .:: .:::.:.: :: :. :.. .. .::.:.:.:
NP_057 PDCKVPG--DDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE
40 50 60 70 80
>>NP_001002248 (OMIM: 614534) anaphase-promoting complex (84 aa)
initn: 219 init1: 92 opt: 256 Z-score: 278.0 bits: 56.2 E(85289): 9.5e-09
Smith-Waterman score: 256; 37.2% identity (67.9% similar) in 78 aa overlap (32-106:5-80)
10 20 30 40 50 60
pF1KE1 ADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDAC
.: ::.:: : : .. ..:.:::. :
NP_001 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCC
10 20 30
70 80 90 100 110
pF1KE1 LRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNN---RCPLCQQDWVVQRIGK
:.. . .:: .:::.:.: :: :. :.. .. .::.:.:.:
NP_001 PDCKVPG--DDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE
40 50 60 70 80
>>NP_001002247 (OMIM: 614534) anaphase-promoting complex (84 aa)
initn: 219 init1: 92 opt: 256 Z-score: 278.0 bits: 56.2 E(85289): 9.5e-09
Smith-Waterman score: 256; 37.2% identity (67.9% similar) in 78 aa overlap (32-106:5-80)
10 20 30 40 50 60
pF1KE1 ADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDAC
.: ::.:: : : .. ..:.:::. :
NP_001 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCC
10 20 30
70 80 90 100 110
pF1KE1 LRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNN---RCPLCQQDWVVQRIGK
:.. . .:: .:::.:.: :: :. :.. .. .::.:.:.:
NP_001 PDCKVPG--DDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE
40 50 60 70 80
113 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:07:45 2016 done: Mon Nov 7 02:07:45 2016
Total Scan time: 4.460 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]