Result of FASTA (omim) for
pFN21AE1409
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1409, 468 aa
1>>>pF1KE1409 468 - 468 aa - 468 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7064+/-0.000342; mu= 13.6283+/- 0.021
mean_var=152.5965+/-30.483, 0's: 0 Z-trim(120.2): 57 B-trim: 516 in 2/49
Lambda= 0.103825
statistics sampled from 34982 (35039) to 34982 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.411), width: 16
Scan time: 9.840
The best scores are: opt bits E(85289)
NP_003835 (OMIM: 603611) tumor necrosis factor rec ( 468) 3235 496.2 7.9e-140
NP_671716 (OMIM: 275355,603612) tumor necrosis fac ( 411) 1333 211.2 4.2e-54
XP_016869433 (OMIM: 275355,603612) PREDICTED: tumo ( 375) 713 118.3 3.6e-26
NP_003833 (OMIM: 275355,603612) tumor necrosis fac ( 440) 713 118.4 4e-26
NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259) 644 107.8 3.6e-23
NP_003831 (OMIM: 603614) tumor necrosis factor rec ( 386) 632 106.2 1.6e-22
NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 256 49.6 9.2e-06
NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 256 49.7 9.9e-06
NP_000034 (OMIM: 134637,601859) tumor necrosis fac ( 335) 256 49.8 1.3e-05
XP_011538069 (OMIM: 134637,601859) PREDICTED: tumo ( 350) 256 49.9 1.4e-05
XP_006717882 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 256 49.9 1.4e-05
XP_011538068 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 256 49.9 1.4e-05
XP_011538066 (OMIM: 134637,601859) PREDICTED: tumo ( 389) 256 49.9 1.5e-05
NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314) 224 45.0 0.00035
XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368) 224 45.1 0.00039
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 216 43.7 0.0007
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 218 44.2 0.0008
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 216 43.9 0.00095
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 216 44.0 0.001
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 206 42.5 0.003
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 206 42.5 0.003
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 206 42.5 0.0031
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 206 42.5 0.0031
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 203 42.0 0.0039
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 203 42.0 0.0039
>>NP_003835 (OMIM: 603611) tumor necrosis factor recepto (468 aa)
initn: 3235 init1: 3235 opt: 3235 Z-score: 2631.3 bits: 496.2 E(85289): 7.9e-140
Smith-Waterman score: 3235; 99.8% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KE1 MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTG
370 380 390 400 410 420
430 440 450 460
pF1KE1 RNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::::::::::::::::::::.:::::::::::::::::::::::::::
NP_003 RNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
430 440 450 460
>>NP_671716 (OMIM: 275355,603612) tumor necrosis factor (411 aa)
initn: 1334 init1: 648 opt: 1333 Z-score: 1092.3 bits: 211.2 E(85289): 4.2e-54
Smith-Waterman score: 1374; 56.1% identity (71.5% similar) in 417 aa overlap (60-466:5-411)
30 40 50 60 70 80
pF1KE1 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
::..:.: :: ..:::: :: : : ::
NP_671 MEQRGQNAPAASGARKRHGPGPREARGARPGPRV
10 20 30
90 100 110 120 130 140
pF1KE1 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
::. .::..::: .: . .: : .: : . :: . :: ::::: : ::
NP_671 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
: : : :.. :.:. :: :: : : : : :::::::::.:::. ::::...: :::
NP_671 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
100 110 120 130 140 150
210 220 230 240 250
pF1KE1 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGN--GHNIW-VILVVTLVV--PLLLVAVLI
::: ::::::::: :::::::::::::::: : .. :.:.:.. : :: ::
NP_671 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLP
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 VCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQE
: :: ::::. .:: . ::::::. :::.: . : : ::.:: ::
NP_671 YLKGICSGGGGDPERVDRSS-------QRPGAEDNVLNEIVSILQ--PTQVPEQEMEVQE
220 230 240 250 260
320 330 340 350 360 370
pF1KE1 PADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDKFANIVPFDS
::. :::.. ::::.. :: ::::: ::::::::::: .:::::: :: ::..:::::
NP_671 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE1 WDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERH
:. :::.: : ::: :..: .:: :.::.::.::::::::.::.:::::::: . ::
NP_671 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
330 340 350 360 370 380
440 450 460
pF1KE1 AKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::.::.: :..::::.::: .. ::.:
NP_671 AKQKIEDHLLSSGKFMYLEGNADSAMS
390 400 410
>>XP_016869433 (OMIM: 275355,603612) PREDICTED: tumor ne (375 aa)
initn: 1182 init1: 648 opt: 713 Z-score: 590.9 bits: 118.3 E(85289): 3.6e-26
Smith-Waterman score: 1167; 53.6% identity (68.9% similar) in 366 aa overlap (135-466:19-375)
110 120 130 140 150 160
pF1KE1 PSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFAC
: : :: : : : :.. :.:. :
XP_016 MDDVWGMRTIEAPNSTAQGHHISEDGRDCISCKYGQDYSTHWNDLLFC
10 20 30 40
170 180 190 200 210 220
pF1KE1 LPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPW
: :: : : : : :::::::::.:::. ::::...: :::::: ::::::::: :::::
XP_016 LRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPW
50 60 70 80 90 100
230 240 250 260
pF1KE1 SDIECVHKESGNGHNIWV----------------------ILVVTLVVPLLLVAVLIVCC
:::::::::::. :. : :.. . :. ..:.....::
XP_016 SDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCK
110 120 130 140 150 160
270 280 290 300 310
pF1KE1 C------------IGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFV
: :: ::::. .:: . ::::::. :::.: . : :
XP_016 SLLWKKVLPYLKGICSGGGGDPERVDRSS-------QRPGAEDNVLNEIVSILQP--TQV
170 180 190 200 210
320 330 340 350 360 370
pF1KE1 SEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDK
::.:: ::::. :::.. ::::.. :: ::::: ::::::::::: .:::::: ::
XP_016 PEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDD
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 FANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLD
::..::::::. :::.: : ::: :..: .:: :.::.::.::::::::.::.:::::
XP_016 FADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLD
280 290 300 310 320 330
440 450 460
pF1KE1 ALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::: . :: ::.::.: :..::::.::: .. ::.:
XP_016 ALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
340 350 360 370
>>NP_003833 (OMIM: 275355,603612) tumor necrosis factor (440 aa)
initn: 1381 init1: 648 opt: 713 Z-score: 590.0 bits: 118.4 E(85289): 4e-26
Smith-Waterman score: 1338; 52.0% identity (67.9% similar) in 446 aa overlap (60-466:5-440)
30 40 50 60 70 80
pF1KE1 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
::..:.: :: ..:::: :: : : ::
NP_003 MEQRGQNAPAASGARKRHGPGPREARGARPGPRV
10 20 30
90 100 110 120 130 140
pF1KE1 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
::. .::..::: .: . .: : .: : . :: . :: ::::: : ::
NP_003 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
: : : :.. :.:. :: :: : : : : :::::::::.:::. ::::...: :::
NP_003 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
100 110 120 130 140 150
210 220 230 240
pF1KE1 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNIWV----------------------
::: ::::::::: ::::::::::::::::. :. :
NP_003 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSG
160 170 180 190 200 210
250 260 270 280 290
pF1KE1 ILVVTLVVPLLLVAVLIVCCC------------IGSGCGGDPKCMDRVCFWRLGLLRGPG
:.. . :. ..:.....:: : :: ::::. .:: . ::
NP_003 IIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSS-------QRPG
220 230 240 250 260
300 310 320 330 340 350
pF1KE1 AEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRR
::::. :::.: . : : ::.:: ::::. :::.. ::::.. :: ::::: :::::
NP_003 AEDNVLNEIVSILQ--PTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRR
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE1 LLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYA
:::::: .:::::: :: ::..::::::. :::.: : ::: :..: .:: :.::.
NP_003 LLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYT
330 340 350 360 370 380
420 430 440 450 460
pF1KE1 MLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::.::::::::.::.:::::::: . :: ::.::.: :..::::.::: .. ::.:
NP_003 MLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
390 400 410 420 430 440
>>NP_003832 (OMIM: 603613) tumor necrosis factor recepto (259 aa)
initn: 616 init1: 490 opt: 644 Z-score: 537.1 bits: 107.8 E(85289): 3.6e-23
Smith-Waterman score: 644; 60.0% identity (80.0% similar) in 155 aa overlap (87-236:3-156)
60 70 80 90 100 110
pF1KE1 TSMGQHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVV--GVLLQVVPSSAATIKLH
:. ::.::::: .::: :. ::.: . .
NP_003 MARIPKTLKFVVVIVAVLLPVLAYSATTARQE
10 20 30
120 130 140 150 160 170
pF1KE1 D---QSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACK
. :... :: .:: :: :: ::::::: :::: ::::: ::::::: .:.:::.::
NP_003 EVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCK
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 SDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVH
::....: :: ::.:.:::: :::::.:: :::::::: :: : :.:..:: :.::.::.
NP_003 SDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSR-CPSGEVQVSNCTSWDDIQCVE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 KESGNGHNIWVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGA
. ..:
NP_003 EFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEE
160 170 180 190 200 210
>>NP_003831 (OMIM: 603614) tumor necrosis factor recepto (386 aa)
initn: 1038 init1: 517 opt: 632 Z-score: 525.2 bits: 106.2 E(85289): 1.6e-22
Smith-Waterman score: 913; 44.2% identity (57.6% similar) in 443 aa overlap (60-466:5-384)
30 40 50 60 70 80
pF1KE1 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
:: :.: ::::: :: : : . : :
NP_003 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLD
10 20 30
90 100 110 120 130 140
pF1KE1 HKTFKFVV--VGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHP
: .:::: :.::: : .:: :: .: :... :: ..: : :: ::::::.
NP_003 PKILKFVVFIVAVLLPVRVDSA-TIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYT
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 GACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAE
:::: ::::: :: ::::: .:: ::.::: . ..: :::::.:.:::. :.:.. :: :
NP_003 GACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPE
100 110 120 130 140 150
210 220 230 240
pF1KE1 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKE--SGNGHNI------------------WV
::: : :::::::::..::: :::.: .. :..:.. ..
NP_003 MCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYHYL
160 170 180 190 200 210
250 260 270 280 290
pF1KE1 ILVVTLVVPLLLVAVLIVC--------CCIGSGCGGDPKCMDRVCFWRLGL-LRGPGAED
:..:.::. : .:.: . : : :: :: :. . :: : : . : :::::
NP_003 IIIVVLVIILAVVVVGFSCRKKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAED
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 NAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLV
::.:: ::: : ::::....:: :.::::::. : : : :: ::::: :::::::
NP_003 NARNETLSNRYLQPTQVSEQEIQGQELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 PANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLM
:.: ::
NP_003 PVNDAD------------------------------------------------------
420 430 440 450 460
pF1KE1 KWVNKTGRNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
.:.: ::::: .:: :::: ::: :: : :..: :: .:::.:
NP_003 --------SADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
340 350 360 370 380
>>NP_001307548 (OMIM: 134637,601859) tumor necrosis fact (197 aa)
initn: 176 init1: 116 opt: 256 Z-score: 224.5 bits: 49.6 E(85289): 9.2e-06
Smith-Waterman score: 256; 33.6% identity (56.6% similar) in 143 aa overlap (122-254:57-188)
100 110 120 130 140
pF1KE1 FKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRS-------EHPGA
:. :.: :::: ... ..:
NP_001 VTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKP----CPPGERKARDCTVNGDEPD-
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDE--EERSPCTTTRNTACQCKPGTFRNDNSAE
: : :: ::. .. : : : . : . :: :.:: :.:::. : :.. :
NP_001 CVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCE
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE1 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI-WVILVVTLVVPLLLVAVLIVC
: :.. : .:..: .:: :. .: :: :. :. :. :.. : .::..
NP_001 HCDPCTK-CEHGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLL-LPIPLIVWGNSGNK
150 160 170 180 190
270 280 290 300 310 320
pF1KE1 CCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPA
NP_001 FI
>>NP_690611 (OMIM: 134637,601859) tumor necrosis factor (220 aa)
initn: 176 init1: 116 opt: 256 Z-score: 223.9 bits: 49.7 E(85289): 9.9e-06
Smith-Waterman score: 256; 33.6% identity (56.6% similar) in 143 aa overlap (122-254:57-188)
100 110 120 130 140
pF1KE1 FKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRS-------EHPGA
:. :.: :::: ... ..:
NP_690 VTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKP----CPPGERKARDCTVNGDEPD-
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDE--EERSPCTTTRNTACQCKPGTFRNDNSAE
: : :: ::. .. : : : . : . :: :.:: :.:::. : :.. :
NP_690 CVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCE
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE1 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI-WVILVVTLVVPLLLVAVLIVC
: :.. : .:..: .:: :. .: :: :. :. :. :.. : .::..
NP_690 HCDPCTK-CEHGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLL-LPIPLIVWVKRKEV
150 160 170 180 190
270 280 290 300 310 320
pF1KE1 CCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPA
NP_690 QKTCRKHRKENQGSHESPTLNPMLT
200 210 220
>>NP_000034 (OMIM: 134637,601859) tumor necrosis factor (335 aa)
initn: 176 init1: 116 opt: 256 Z-score: 221.6 bits: 49.8 E(85289): 1.3e-05
Smith-Waterman score: 256; 33.6% identity (56.6% similar) in 143 aa overlap (122-254:57-188)
100 110 120 130 140
pF1KE1 FKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRS-------EHPGA
:. :.: :::: ... ..:
NP_000 VTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKP----CPPGERKARDCTVNGDEPD-
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDE--EERSPCTTTRNTACQCKPGTFRNDNSAE
: : :: ::. .. : : : . : . :: :.:: :.:::. : :.. :
NP_000 CVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCE
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE1 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI-WVILVVTLVVPLLLVAVLIVC
: :.. : .:..: .:: :. .: :: :. :. :. :.. : .::..
NP_000 HCDPCTK-CEHGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLL-LPIPLIVWVKRKEV
150 160 170 180 190
270 280 290 300 310 320
pF1KE1 CCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPA
NP_000 QKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVN
200 210 220 230 240 250
>>XP_011538069 (OMIM: 134637,601859) PREDICTED: tumor ne (350 aa)
initn: 176 init1: 116 opt: 256 Z-score: 221.3 bits: 49.9 E(85289): 1.4e-05
Smith-Waterman score: 256; 33.6% identity (56.6% similar) in 143 aa overlap (122-254:72-203)
100 110 120 130 140
pF1KE1 FKFVVVGVLLQVVPSSAATIKLHDQSIGTQQWEHSPLGELCPPGSHRS-------EHPGA
:. :.: :::: ... ..:
XP_011 VTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKP----CPPGERKARDCTVNGDEPD-
50 60 70 80 90
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDE--EERSPCTTTRNTACQCKPGTFRNDNSAE
: : :: ::. .. : : : . : . :: :.:: :.:::. : :.. :
XP_011 CVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCE
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI-WVILVVTLVVPLLLVAVLIVC
: :.. : .:..: .:: :. .: :: :. :. :. :.. : .::..
XP_011 HCDPCTK-CEHGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLL-LPIPLIVWVKRKEV
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 CCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPA
XP_011 QKTCRKHRKENQGSHESPTLNPETVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVN
220 230 240 250 260 270
468 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:39:12 2016 done: Mon Nov 7 01:39:14 2016
Total Scan time: 9.840 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]