Result of FASTA (ccds) for
pFN21AE1409
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1409, 468 aa
1>>>pF1KE1409 468 - 468 aa - 468 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7169+/-0.000835; mu= 13.6354+/- 0.050
mean_var=148.6885+/-28.652, 0's: 0 Z-trim(113.0): 25 B-trim: 0 in 0/51
Lambda= 0.105181
statistics sampled from 13683 (13706) to 13683 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.421), width: 16
Scan time: 3.370
The best scores are: opt bits E(32554)
CCDS6039.1 TNFRSF10A gene_id:8797|Hs108|chr8 ( 468) 3235 502.4 4.2e-142
CCDS6036.1 TNFRSF10B gene_id:8795|Hs108|chr8 ( 411) 1333 213.7 2.9e-55
CCDS6035.1 TNFRSF10B gene_id:8795|Hs108|chr8 ( 440) 713 119.7 6.4e-27
CCDS6037.1 TNFRSF10C gene_id:8794|Hs108|chr8 ( 259) 644 109.0 6.3e-24
CCDS6038.1 TNFRSF10D gene_id:8793|Hs108|chr8 ( 386) 632 107.3 2.9e-23
>>CCDS6039.1 TNFRSF10A gene_id:8797|Hs108|chr8 (468 aa)
initn: 3235 init1: 3235 opt: 3235 Z-score: 2664.7 bits: 502.4 E(32554): 4.2e-142
Smith-Waterman score: 3235; 99.8% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KE1 MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 QHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 QQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 TTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 WVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 WVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 SNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 TETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTG
370 380 390 400 410 420
430 440 450 460
pF1KE1 RNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::::::::::::::::::::.:::::::::::::::::::::::::::
CCDS60 RNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
430 440 450 460
>>CCDS6036.1 TNFRSF10B gene_id:8795|Hs108|chr8 (411 aa)
initn: 1334 init1: 648 opt: 1333 Z-score: 1105.6 bits: 213.7 E(32554): 2.9e-55
Smith-Waterman score: 1374; 56.1% identity (71.5% similar) in 417 aa overlap (60-466:5-411)
30 40 50 60 70 80
pF1KE1 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
::..:.: :: ..:::: :: : : ::
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARPGPRV
10 20 30
90 100 110 120 130 140
pF1KE1 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
::. .::..::: .: . .: : .: : . :: . :: ::::: : ::
CCDS60 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
: : : :.. :.:. :: :: : : : : :::::::::.:::. ::::...: :::
CCDS60 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
100 110 120 130 140 150
210 220 230 240 250
pF1KE1 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGN--GHNIW-VILVVTLVV--PLLLVAVLI
::: ::::::::: :::::::::::::::: : .. :.:.:.. : :: ::
CCDS60 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLP
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 VCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEILSNADSLSTFVSEQQMESQE
: :: ::::. .:: . ::::::. :::.: . : : ::.:: ::
CCDS60 YLKGICSGGGGDPERVDRSS-------QRPGAEDNVLNEIVSILQ--PTQVPEQEMEVQE
220 230 240 250 260
320 330 340 350 360 370
pF1KE1 PADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDKFANIVPFDS
::. :::.. ::::.. :: ::::: ::::::::::: .:::::: :: ::..:::::
CCDS60 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE1 WDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERH
:. :::.: : ::: :..: .:: :.::.::.::::::::.::.:::::::: . ::
CCDS60 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
330 340 350 360 370 380
440 450 460
pF1KE1 AKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::.::.: :..::::.::: .. ::.:
CCDS60 AKQKIEDHLLSSGKFMYLEGNADSAMS
390 400 410
>>CCDS6035.1 TNFRSF10B gene_id:8795|Hs108|chr8 (440 aa)
initn: 1381 init1: 648 opt: 713 Z-score: 596.8 bits: 119.7 E(32554): 6.4e-27
Smith-Waterman score: 1338; 52.0% identity (67.9% similar) in 446 aa overlap (60-466:5-440)
30 40 50 60 70 80
pF1KE1 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
::..:.: :: ..:::: :: : : ::
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARPGPRV
10 20 30
90 100 110 120 130 140
pF1KE1 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
::. .::..::: .: . .: : .: : . :: . :: ::::: : ::
CCDS60 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
: : : :.. :.:. :: :: : : : : :::::::::.:::. ::::...: :::
CCDS60 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
100 110 120 130 140 150
210 220 230 240
pF1KE1 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNIWV----------------------
::: ::::::::: ::::::::::::::::. :. :
CCDS60 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSG
160 170 180 190 200 210
250 260 270 280 290
pF1KE1 ILVVTLVVPLLLVAVLIVCCC------------IGSGCGGDPKCMDRVCFWRLGLLRGPG
:.. . :. ..:.....:: : :: ::::. .:: . ::
CCDS60 IIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSS-------QRPG
220 230 240 250 260
300 310 320 330 340 350
pF1KE1 AEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRR
::::. :::.: . : : ::.:: ::::. :::.. ::::.. :: ::::: :::::
CCDS60 AEDNVLNEIVSILQ--PTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRR
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE1 LLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYA
:::::: .:::::: :: ::..::::::. :::.: : ::: :..: .:: :.::.
CCDS60 LLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYT
330 340 350 360 370 380
420 430 440 450 460
pF1KE1 MLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
::.::::::::.::.:::::::: . :: ::.::.: :..::::.::: .. ::.:
CCDS60 MLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
390 400 410 420 430 440
>>CCDS6037.1 TNFRSF10C gene_id:8794|Hs108|chr8 (259 aa)
initn: 616 init1: 490 opt: 644 Z-score: 543.1 bits: 109.0 E(32554): 6.3e-24
Smith-Waterman score: 644; 60.0% identity (80.0% similar) in 155 aa overlap (87-236:3-156)
60 70 80 90 100 110
pF1KE1 TSMGQHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVV--GVLLQVVPSSAATIKLH
:. ::.::::: .::: :. ::.: . .
CCDS60 MARIPKTLKFVVVIVAVLLPVLAYSATTARQE
10 20 30
120 130 140 150 160 170
pF1KE1 D---QSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACK
. :... :: .:: :: :: ::::::: :::: ::::: ::::::: .:.:::.::
CCDS60 EVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCK
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 SDEEERSPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVH
::....: :: ::.:.:::: :::::.:: :::::::: :: : :.:..:: :.::.::.
CCDS60 SDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSR-CPSGEVQVSNCTSWDDIQCVE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 KESGNGHNIWVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGA
. ..:
CCDS60 EFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEE
160 170 180 190 200 210
>>CCDS6038.1 TNFRSF10D gene_id:8793|Hs108|chr8 (386 aa)
initn: 1038 init1: 517 opt: 632 Z-score: 531.1 bits: 107.3 E(32554): 2.9e-23
Smith-Waterman score: 913; 44.2% identity (57.6% similar) in 443 aa overlap (60-466:5-384)
30 40 50 60 70 80
pF1KE1 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
:: :.: ::::: :: : : . : :
CCDS60 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLD
10 20 30
90 100 110 120 130 140
pF1KE1 HKTFKFVV--VGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHP
: .:::: :.::: : .:: :: .: :... :: ..: : :: ::::::.
CCDS60 PKILKFVVFIVAVLLPVRVDSA-TIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYT
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 GACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAE
:::: ::::: :: ::::: .:: ::.::: . ..: :::::.:.:::. :.:.. :: :
CCDS60 GACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPE
100 110 120 130 140 150
210 220 230 240
pF1KE1 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKE--SGNGHNI------------------WV
::: : :::::::::..::: :::.: .. :..:.. ..
CCDS60 MCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYHYL
160 170 180 190 200 210
250 260 270 280 290
pF1KE1 ILVVTLVVPLLLVAVLIVC--------CCIGSGCGGDPKCMDRVCFWRLGL-LRGPGAED
:..:.::. : .:.: . : : :: :: :. . :: : : . : :::::
CCDS60 IIIVVLVIILAVVVVGFSCRKKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAED
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 NAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLV
::.:: ::: : ::::....:: :.::::::. : : : :: ::::: :::::::
CCDS60 NARNETLSNRYLQPTQVSEQEIQGQELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 PANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLM
:.: ::
CCDS60 PVNDAD------------------------------------------------------
420 430 440 450 460
pF1KE1 KWVNKTGRNASIHTLLDALERMEERHAKEKIQDLLVDSGKFIYLEDGTGSAVSLE
.:.: ::::: .:: :::: ::: :: : :..: :: .:::.:
CCDS60 --------SADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
340 350 360 370 380
468 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:39:11 2016 done: Mon Nov 7 01:39:12 2016
Total Scan time: 3.370 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]