Result of FASTA (omim) for
pFN21AE1402
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1402, 599 aa
1>>>pF1KE1402 599 - 599 aa - 599 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0429+/-0.000368; mu= 15.5360+/- 0.023
mean_var=93.7326+/-18.091, 0's: 0 Z-trim(115.4): 187 B-trim: 38 in 1/56
Lambda= 0.132473
statistics sampled from 25598 (25804) to 25598 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.303), width: 16
Scan time: 10.870
The best scores are: opt bits E(85289)
NP_000953 (OMIM: 176805) prostaglandin G/H synthas ( 599) 4161 805.9 0
XP_011517177 (OMIM: 176805) PREDICTED: prostagland ( 574) 3969 769.2 0
XP_005252162 (OMIM: 176805) PREDICTED: prostagland ( 574) 3969 769.2 0
XP_016870418 (OMIM: 176805) PREDICTED: prostagland ( 574) 3969 769.2 0
XP_011517178 (OMIM: 176805) PREDICTED: prostagland ( 490) 3353 651.4 2e-186
NP_001258094 (OMIM: 176805) prostaglandin G/H synt ( 490) 3353 651.4 2e-186
NP_001258093 (OMIM: 176805) prostaglandin G/H synt ( 551) 2980 580.2 6.3e-165
NP_542158 (OMIM: 176805) prostaglandin G/H synthas ( 562) 2799 545.6 1.7e-154
NP_000954 (OMIM: 600262) prostaglandin G/H synthas ( 604) 2660 519.0 1.8e-146
NP_001258297 (OMIM: 176805) prostaglandin G/H synt ( 537) 2607 508.9 1.8e-143
NP_001258296 (OMIM: 176805) prostaglandin G/H synt ( 453) 1991 391.1 4.3e-108
NP_001258095 (OMIM: 176805) prostaglandin G/H synt ( 453) 1991 391.1 4.3e-108
>>NP_000953 (OMIM: 176805) prostaglandin G/H synthase 1 (599 aa)
initn: 4161 init1: 4161 opt: 4161 Z-score: 4301.2 bits: 805.9 E(85289): 0
Smith-Waterman score: 4161; 99.8% identity (99.8% similar) in 599 aa overlap (1-599:1-599)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
490 500 510 520 530 540
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
550 560 570 580 590
>>XP_011517177 (OMIM: 176805) PREDICTED: prostaglandin G (574 aa)
initn: 3964 init1: 3964 opt: 3969 Z-score: 4103.2 bits: 769.2 E(85289): 0
Smith-Waterman score: 3969; 99.5% identity (99.6% similar) in 571 aa overlap (29-599:4-574)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
: .::::::::::::::::::::::::::::
XP_011 MRKPRLMNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
460 470 480 490 500 510
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
520 530 540 550 560 570
>>XP_005252162 (OMIM: 176805) PREDICTED: prostaglandin G (574 aa)
initn: 3964 init1: 3964 opt: 3969 Z-score: 4103.2 bits: 769.2 E(85289): 0
Smith-Waterman score: 3969; 99.5% identity (99.6% similar) in 571 aa overlap (29-599:4-574)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
: .::::::::::::::::::::::::::::
XP_005 MRKPRLMNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
460 470 480 490 500 510
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
520 530 540 550 560 570
>>XP_016870418 (OMIM: 176805) PREDICTED: prostaglandin G (574 aa)
initn: 3964 init1: 3964 opt: 3969 Z-score: 4103.2 bits: 769.2 E(85289): 0
Smith-Waterman score: 3969; 99.5% identity (99.6% similar) in 571 aa overlap (29-599:4-574)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
: .::::::::::::::::::::::::::::
XP_016 MRKPRLMNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
460 470 480 490 500 510
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
520 530 540 550 560 570
>>XP_011517178 (OMIM: 176805) PREDICTED: prostaglandin G (490 aa)
initn: 3353 init1: 3353 opt: 3353 Z-score: 3467.9 bits: 651.4 E(85289): 2e-186
Smith-Waterman score: 3353; 100.0% identity (100.0% similar) in 490 aa overlap (110-599:1-490)
80 90 100 110 120 130
pF1KE1 SLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWE
::::::::::::::::::::::::::::::
XP_011 MLMRLVLTVRSNLIPSPPTYNSAHDYISWE
10 20 30
140 150 160 170 180 190
pF1KE1 SFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 FAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 MYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEH
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 PTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAME
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNM
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 DHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 LEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVK
400 410 420 430 440 450
560 570 580 590
pF1KE1 TATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
::::::::::::::::::::::::::::::::::::::::
XP_011 TATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
460 470 480 490
>>NP_001258094 (OMIM: 176805) prostaglandin G/H synthase (490 aa)
initn: 3353 init1: 3353 opt: 3353 Z-score: 3467.9 bits: 651.4 E(85289): 2e-186
Smith-Waterman score: 3353; 100.0% identity (100.0% similar) in 490 aa overlap (110-599:1-490)
80 90 100 110 120 130
pF1KE1 SLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWE
::::::::::::::::::::::::::::::
NP_001 MLMRLVLTVRSNLIPSPPTYNSAHDYISWE
10 20 30
140 150 160 170 180 190
pF1KE1 SFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 FAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 MYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEH
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 PTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAME
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNM
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 DHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 LEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVK
400 410 420 430 440 450
560 570 580 590
pF1KE1 TATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
::::::::::::::::::::::::::::::::::::::::
NP_001 TATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
460 470 480 490
>>NP_001258093 (OMIM: 176805) prostaglandin G/H synthase (551 aa)
initn: 2970 init1: 2970 opt: 2980 Z-score: 3081.9 bits: 580.2 E(85289): 6.3e-165
Smith-Waterman score: 3718; 91.8% identity (91.8% similar) in 599 aa overlap (1-599:1-551)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLT---
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
:::::::::::::::
NP_001 ---------------------------------------------GKKQLPDAQLLARRF
120 130
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
440 450 460 470 480 490
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
500 510 520 530 540 550
>>NP_542158 (OMIM: 176805) prostaglandin G/H synthase 1 (562 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 2894.8 bits: 545.6 E(85289): 1.7e-154
Smith-Waterman score: 3842; 93.7% identity (93.7% similar) in 599 aa overlap (1-599:1-562)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
:::::::::::::::::::::::::::::::::::
NP_542 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK-------------------------
370 380 390
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 ------------IGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
400 410 420 430 440
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
450 460 470 480 490 500
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
510 520 530 540 550 560
>>NP_000954 (OMIM: 600262) prostaglandin G/H synthase 2 (604 aa)
initn: 2362 init1: 2362 opt: 2660 Z-score: 2750.8 bits: 519.0 E(85289): 1.8e-146
Smith-Waterman score: 2660; 64.7% identity (87.5% similar) in 552 aa overlap (33-583:19-570)
10 20 30 40 50 60
pF1KE1 RSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTG
:::: .:::..:.:. :.:.:.:::::::
NP_000 MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTG
10 20 30 40
70 80 90 100 110 120
pF1KE1 YSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNAT-FIREMLMRLVLTVRSN
. : ::. : . : .. :.:.:. .:..::: . ::. :: :.:. .: ::: ::.
NP_000 FYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 LIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFL
:: ::::::. . : :::.:::.::::: :: :: :::::.:.::::::::.. .....:
NP_000 LIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 LRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQY
:::::::::::.:.::::::::::::::::. : ::.::..:::::::.::::..: ::
NP_000 LRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 QLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYA
.::::::::.:::..:::::::.:... . : :: .: . ..:::::::::.::::.::
NP_000 KLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD
:.::::::::::.:: ::: :::::::::.::::::::::::::.:::.:::: ..::::
NP_000 TIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE1 PELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEAL
:::::. ::::.:::: ::: :::::::.::.:.. .:.:.:.::..:.:.:...:. .
NP_000 PELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQF
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE1 VDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELV
:..:.::::::..::::. . .:. : .::.:. : :::::::: .::: ::.::.
NP_000 VESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELT
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE1 GEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSP
:::::.:::: :::::::.:.::.::.:: .:..::::.:.:.:::::::::.:: ::::
NP_000 GEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSP
470 480 490 500 510 520
550 560 570 580 590
pF1KE1 EYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::.:..::....:.: :.: ::..:: :::
NP_000 AYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGL
530 540 550 560 570 580
NP_000 DDINPTVLLKERSTEL
590 600
>>NP_001258297 (OMIM: 176805) prostaglandin G/H synthase (537 aa)
initn: 2601 init1: 2601 opt: 2607 Z-score: 2696.8 bits: 508.9 E(85289): 1.8e-143
Smith-Waterman score: 3650; 93.0% identity (93.2% similar) in 571 aa overlap (29-599:4-537)
10 20 30 40 50 60
pF1KE1 MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
: .::::::::::::::::::::::::::::
NP_001 MRKPRLMNPCCYYPCQHQGICVRFGLDRYQCDCTR
10 20 30
70 80 90 100 110 120
pF1KE1 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
:::::::::::::::::::::::::::::::::::
NP_001 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK-------------------------
340 350 360 370
430 440 450 460 470 480
pF1KE1 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------IGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
380 390 400 410
490 500 510 520 530 540
pF1KE1 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
420 430 440 450 460 470
550 560 570 580 590
pF1KE1 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
480 490 500 510 520 530
599 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:30:37 2016 done: Sun Nov 6 22:30:38 2016
Total Scan time: 10.870 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]