Result of FASTA (ccds) for
pFN21AE1387
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1387, 982 aa
1>>>pF1KE1387 982 - 982 aa - 982 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.0724+/-0.00112; mu= -6.8691+/- 0.068
mean_var=457.1890+/-93.916, 0's: 0 Z-trim(115.8): 18 B-trim: 520 in 2/54
Lambda= 0.059983
statistics sampled from 16373 (16388) to 16373 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.503), width: 16
Scan time: 4.120
The best scores are: opt bits E(32554)
CCDS2948.1 CBLB gene_id:868|Hs108|chr3 ( 982) 6926 614.5 3.4e-175
CCDS8418.1 CBL gene_id:867|Hs108|chr11 ( 906) 2587 238.9 3.4e-62
CCDS12643.1 CBLC gene_id:23624|Hs108|chr19 ( 474) 1408 136.7 1.1e-31
CCDS46109.1 CBLC gene_id:23624|Hs108|chr19 ( 428) 700 75.3 2.9e-13
>>CCDS2948.1 CBLB gene_id:868|Hs108|chr3 (982 aa)
initn: 6926 init1: 6926 opt: 6926 Z-score: 3258.8 bits: 614.5 E(32554): 3.4e-175
Smith-Waterman score: 6926; 99.9% identity (100.0% similar) in 982 aa overlap (1-982:1-982)
10 20 30 40 50 60
pF1KE1 MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 QNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 AIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 FWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 QPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 TGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 ELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 IIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 IIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 PGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSKDPPMPLEAWCPRDVFG
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
CCDS29 DKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 TNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 TNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 GSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 GSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 SQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 SQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 ARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 ARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 SSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 SSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 APARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS29 APARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNV
910 920 930 940 950 960
970 980
pF1KE1 EVARSILREFAFPPPVSPRLNL
::::::::::::::::::::::
CCDS29 EVARSILREFAFPPPVSPRLNL
970 980
>>CCDS8418.1 CBL gene_id:867|Hs108|chr11 (906 aa)
initn: 2823 init1: 2118 opt: 2587 Z-score: 1230.0 bits: 238.9 E(32554): 3.4e-62
Smith-Waterman score: 2878; 50.6% identity (66.6% similar) in 998 aa overlap (11-970:13-895)
10 20 30 40 50
pF1KE1 MANSMNGRNPGGRG-GNPRKGRILGII-DAIQDA------VGPPKQAAADRRTVEKTW
:: : :. .: ..:.. ::.: ..: ...:.. ::: :
CCDS84 MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIY
::::::::::::::: ::::::::::.::::::::: :::.:. :. :.:::::...
CCDS84 KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEG--KMETLGENEYFRVF
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 IDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDN
...::::.:..: ::::::::::::.:: :::::::::::::::::.:.:::.: ::::.
CCDS84 MENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 FRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISV
:::::::::::::: ::.::::::: ::: ::::: ::::::::::::::::::::::::
CCDS84 FRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 FEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCT
:::::::::::::.:.::::: :::::::::::::::::::::::. ::::::::::::
CCDS84 FEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 RLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPH
:::::::::::.::::::::::::::::::::: ::::::.::::. ::::::::::::.
CCDS84 RLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 DHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPF
::::::::::::::::::::::::::::::::::::::::::::::::.::::.::::::
CCDS84 DHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPF
360 370 380 390 400 410
420 430 440 450 460
pF1KE1 CRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDR--EESL-MMNRLANV
:::::::::::.::::::: :: . . : : . :::::. ...: ::..::.
CCDS84 CRCEIKGTEPIVVDPFDPRGSGSLLRQGAE--GAPSPNYDDDDDERADDTLFMMKELAG-
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 RKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQI-PHLSLPPVPPRLDLIQKGIVRSPCGSP
:. ..: :.:... :. :::::::::::. . . .:
CCDS84 -------------------AKVERP-PSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASA
480 490 500 510
530 540 550 560 570 580
pF1KE1 TGSPKSSPCMVRKQDKPLPAPPPPLRD-PPPPPPERPPPIPPDNRLSRHIHHVE--SVPS
:. ... ..:::::.:: ::: ::::::.:: . ..: .:. . ::
CCDS84 LGTASKAASGSLHKDKPLPVPPT-LRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPS
520 530 540 550 560 570
590 600 610 620 630
pF1KE1 KD--PPMPL----EAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPV
.: ::.: ..: :: . :: ..: :. :::
CCDS84 RDKLPPVPSSRLGDSWLPRPI----------------PKVPVSAPSS---------SDPW
580 590 600
640 650 660 670 680 690
pF1KE1 LMRK-HRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSE
:. ::.:: ...: .. : : : : . : : .:.:
CCDS84 TGRELTNRHSLP----------------FSLPSQMEPRPDV----PRLGSTFSLDTSMSM
610 620 630 640
700 710 720 730 740 750
pF1KE1 KTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSN
.. : . : :: ..:: : :. : . :
CCDS84 NSSPLVGPECD-------HP-----------KIKP--SSSANAIYSLAARPLP-------
650 660 670 680
760 770 780 790 800 810
pF1KE1 IPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAF--
.: : :. .. : . :. : : : :. .:. : : : .:.
CCDS84 VPKLP---PGEQCEGEEDTEYMTPSSRPLR--PLDTSQSSRA-CDCDQQIDSCTYEAMYN
690 700 710 720 730
820 830 840 850 860 870
pF1KE1 -DALPPSLPPPPPPARHSLIE-HSKP-PGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPP
.. ::. .. .: :.. : : ..: : .:. : ::
CCDS84 IQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYD---VPKPP--------VPAVL
740 750 760 770 780
880 890 900 910 920
pF1KE1 ARRLPGENVKTNRT----SQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHH---RKPHG
::: .. ... . : : : . ..:::.: ::::: ::: : . .. :
CCDS84 ARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSG
790 800 810 820 830 840
930 940 950 960 970 980
pF1KE1 PEA----ALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRL
: : : .....: .::..::.......:: :::::.:.:..:::::
CCDS84 PAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISSPAHVA
850 860 870 880 890 900
pF1KE1 NL
CCDS84 T
>>CCDS12643.1 CBLC gene_id:23624|Hs108|chr19 (474 aa)
initn: 1428 init1: 1310 opt: 1408 Z-score: 682.3 bits: 136.7 E(32554): 1.1e-31
Smith-Waterman score: 1408; 49.4% identity (76.4% similar) in 403 aa overlap (32-426:4-404)
10 20 30 40 50 60
pF1KE1 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
::.: . . :.. .. ...... . :
CCDS12 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
10 20 30
70 80 90 100 110
pF1KE1 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
CCDS12 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
CCDS12 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
CCDS12 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::::: ::::::
CCDS12 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
:::::::..::.:::::: :::: :.:..:...::::::::...::::: : . :...:
CCDS12 QWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRI
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
CCDS12 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE1 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
:::: : . . :
CCDS12 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
400 410 420 430 440 450
>>CCDS46109.1 CBLC gene_id:23624|Hs108|chr19 (428 aa)
initn: 1184 init1: 602 opt: 700 Z-score: 351.7 bits: 75.3 E(32554): 2.9e-13
Smith-Waterman score: 1062; 40.9% identity (65.8% similar) in 403 aa overlap (32-426:4-358)
10 20 30 40 50 60
pF1KE1 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
::.: . . :.. .. ...... . :
CCDS46 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
10 20 30
70 80 90 100 110
pF1KE1 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
CCDS46 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
CCDS46 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
CCDS46 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::
CCDS46 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSY----------
220 230 240 250 260
300 310 320 330 340 350
pF1KE1 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
:::::...::::: : . :...:
CCDS46 ------------------------------------LYPDGKTHNPDLTELGQAEPQQRI
270 280
360 370 380 390 400 410
pF1KE1 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
CCDS46 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
290 300 310 320 330 340
420 430 440 450 460 470
pF1KE1 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
:::: : . . :
CCDS46 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
350 360 370 380 390 400
982 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:02:01 2016 done: Mon Nov 7 00:02:01 2016
Total Scan time: 4.120 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]