Result of FASTA (omim) for
pFN21AE1383
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1383, 689 aa
1>>>pF1KE1383 689 - 689 aa - 689 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6652+/-0.000639; mu= -0.9033+/- 0.038
mean_var=681.7127+/-154.017, 0's: 0 Z-trim(115.2): 1405 B-trim: 33 in 1/51
Lambda= 0.049122
statistics sampled from 23710 (25463) to 23710 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.299), width: 16
Scan time: 12.140
The best scores are: opt bits E(85289)
NP_001610 (OMIM: 109635) beta-adrenergic receptor ( 689) 4654 346.8 1.6e-94
XP_011543075 (OMIM: 109635) PREDICTED: beta-adrene ( 659) 4430 330.9 9.3e-90
NP_005151 (OMIM: 109636) beta-adrenergic receptor ( 688) 4042 303.5 1.8e-81
XP_011528277 (OMIM: 109636) PREDICTED: beta-adrene ( 523) 3166 241.2 7.7e-63
NP_001004105 (OMIM: 600869) G protein-coupled rece ( 560) 1108 95.4 6.4e-19
NP_001004106 (OMIM: 600869) G protein-coupled rece ( 576) 1108 95.4 6.4e-19
NP_002073 (OMIM: 600869) G protein-coupled recepto ( 589) 1108 95.4 6.5e-19
XP_006714922 (OMIM: 600869) PREDICTED: G protein-c ( 557) 1092 94.2 1.4e-18
XP_006714921 (OMIM: 600869) PREDICTED: G protein-c ( 559) 1092 94.3 1.4e-18
NP_005299 (OMIM: 600870) G protein-coupled recepto ( 590) 1089 94.1 1.7e-18
XP_005269765 (OMIM: 600870) PREDICTED: G protein-c ( 558) 1082 93.5 2.3e-18
NP_892027 (OMIM: 137026) G protein-coupled recepto ( 578) 1055 91.7 8.7e-18
NP_001004057 (OMIM: 137026) G protein-coupled rece ( 532) 1042 90.7 1.6e-17
NP_001004056 (OMIM: 137026) G protein-coupled rece ( 546) 1036 90.3 2.2e-17
XP_011532839 (OMIM: 600869) PREDICTED: G protein-c ( 550) 1032 90.0 2.6e-17
NP_005298 (OMIM: 137026) G protein-coupled recepto ( 500) 1023 89.3 3.9e-17
NP_002920 (OMIM: 180381,613411) rhodopsin kinase [ ( 563) 973 85.8 4.8e-16
XP_016861206 (OMIM: 606987) PREDICTED: rhodopsin k ( 553) 930 82.8 4e-15
NP_631948 (OMIM: 606987) rhodopsin kinase [Homo sa ( 553) 930 82.8 4e-15
XP_016863545 (OMIM: 137026) PREDICTED: G protein-c ( 440) 865 78.0 8.7e-14
XP_016863543 (OMIM: 137026) PREDICTED: G protein-c ( 486) 865 78.1 9.1e-14
XP_016863544 (OMIM: 137026) PREDICTED: G protein-c ( 454) 846 76.7 2.2e-13
XP_016863549 (OMIM: 137026) PREDICTED: G protein-c ( 384) 828 75.3 5e-13
XP_016863546 (OMIM: 137026) PREDICTED: G protein-c ( 384) 828 75.3 5e-13
XP_016863548 (OMIM: 137026) PREDICTED: G protein-c ( 384) 828 75.3 5e-13
XP_016863547 (OMIM: 137026) PREDICTED: G protein-c ( 384) 828 75.3 5e-13
XP_016863552 (OMIM: 137026) PREDICTED: G protein-c ( 338) 815 74.2 8.9e-13
XP_011511751 (OMIM: 137026) PREDICTED: G protein-c ( 585) 819 74.9 9.5e-13
XP_016863541 (OMIM: 137026) PREDICTED: G protein-c ( 591) 819 74.9 9.5e-13
XP_011511750 (OMIM: 137026) PREDICTED: G protein-c ( 611) 819 75.0 9.7e-13
XP_011511749 (OMIM: 137026) PREDICTED: G protein-c ( 617) 819 75.0 9.7e-13
XP_011511752 (OMIM: 137026) PREDICTED: G protein-c ( 571) 806 74.0 1.8e-12
XP_016863551 (OMIM: 137026) PREDICTED: G protein-c ( 367) 791 72.6 3e-12
XP_016863550 (OMIM: 137026) PREDICTED: G protein-c ( 367) 791 72.6 3e-12
XP_005248019 (OMIM: 137026) PREDICTED: G protein-c ( 367) 791 72.6 3e-12
XP_006713943 (OMIM: 137026) PREDICTED: G protein-c ( 367) 791 72.6 3e-12
XP_011511755 (OMIM: 137026) PREDICTED: G protein-c ( 525) 743 69.5 3.8e-11
NP_001006945 (OMIM: 603606) ribosomal protein S6 k ( 766) 745 69.9 4.1e-11
NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 744 69.8 4.2e-11
NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 744 69.8 4.2e-11
NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 744 69.8 4.2e-11
NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 743 69.7 4.4e-11
NP_001006933 (OMIM: 601685) ribosomal protein S6 k ( 741) 743 69.7 4.4e-11
NP_001305865 (OMIM: 601685) ribosomal protein S6 k ( 758) 743 69.7 4.5e-11
XP_006715612 (OMIM: 601685) PREDICTED: ribosomal p ( 761) 743 69.8 4.5e-11
NP_001287731 (OMIM: 603606) ribosomal protein S6 k ( 765) 742 69.7 4.7e-11
NP_003933 (OMIM: 603606) ribosomal protein S6 kina ( 772) 742 69.7 4.8e-11
XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710) 738 69.3 5.6e-11
XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711) 738 69.3 5.6e-11
XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711) 738 69.3 5.6e-11
>>NP_001610 (OMIM: 109635) beta-adrenergic receptor kina (689 aa)
initn: 4654 init1: 4654 opt: 4654 Z-score: 1818.1 bits: 346.8 E(85289): 1.6e-94
Smith-Waterman score: 4654; 100.0% identity (100.0% similar) in 689 aa overlap (1-689:1-689)
10 20 30 40 50 60
pF1KE1 MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR
610 620 630 640 650 660
670 680
pF1KE1 VPKMKNKPRSPVVELSKVPLVQRGSANGL
:::::::::::::::::::::::::::::
NP_001 VPKMKNKPRSPVVELSKVPLVQRGSANGL
670 680
>>XP_011543075 (OMIM: 109635) PREDICTED: beta-adrenergic (659 aa)
initn: 4430 init1: 4430 opt: 4430 Z-score: 1732.4 bits: 330.9 E(85289): 9.3e-90
Smith-Waterman score: 4430; 100.0% identity (100.0% similar) in 652 aa overlap (38-689:8-659)
10 20 30 40 50 60
pF1KE1 LADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLL
::::::::::::::::::::::::::::::
XP_011 MGKLKLQSIRSVMQKYLEDRGEVTFEKIFSQKLGYLL
10 20 30
70 80 90 100 110 120
pF1KE1 FRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 ATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLT
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 TGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 MHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 YDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 LLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 FDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 GHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 SVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNK
580 590 600 610 620 630
670 680
pF1KE1 PRSPVVELSKVPLVQRGSANGL
::::::::::::::::::::::
XP_011 PRSPVVELSKVPLVQRGSANGL
640 650
>>NP_005151 (OMIM: 109636) beta-adrenergic receptor kina (688 aa)
initn: 4034 init1: 4034 opt: 4042 Z-score: 1583.7 bits: 303.5 E(85289): 1.8e-81
Smith-Waterman score: 4042; 84.0% identity (96.1% similar) in 689 aa overlap (1-689:1-688)
10 20 30 40 50 60
pF1KE1 MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
::::::::::::::::::::::::::::::.:.:::::::::::::: .:.:.::.:::.
NP_005 MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
::.:.:::.:::::...:: : :.::::::.::::..::.:. :::.:.:.:::::::.:
NP_005 QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
::::::.:.::::.::.:::: ::::::::::..::::.::::.::::::::::::::
NP_005 SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
:::::::::::::::::.::::::::: ::::::::::::::::::::::: .:::::.:
NP_005 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_005 IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
:::::.::::::::::::::::::::::::::::::::::::::::::. :::::.::::
NP_005 VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
:.:::::::::::..:::: : :.::::: ::...::: :.::::::::::::::::::
NP_005 LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
:::::::::::::::::::: :::::.::::.:::::::::.:::....::.::..::::
NP_005 DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
.:::::::::::::::::::::::: :.:::::::::::::::::::::::::::. :.:
NP_005 RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR
::::.: ::::::::..::.:..:.:::::.:::.::::.::::::: ....:::.:..:
NP_005 LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
610 620 630 640 650 660
670 680
pF1KE1 VPKMKNKPRSPVVELSKVPLVQRGSANGL
.::. ::::: .::: : : .:.: :::
NP_005 APKFLNKPRSGTVELPKPSLCHRNS-NGL
670 680
>>XP_011528277 (OMIM: 109636) PREDICTED: beta-adrenergic (523 aa)
initn: 3156 init1: 3156 opt: 3166 Z-score: 1249.2 bits: 241.2 E(85289): 7.7e-63
Smith-Waterman score: 3166; 86.1% identity (96.2% similar) in 524 aa overlap (166-689:1-523)
140 150 160 170 180 190
pF1KE1 LGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHR
.:::::::::::::::::::::::.:::::
XP_011 MESDKFTRFCQWKNVELNIHLTMNEFSVHR
10 20 30
200 210 220 230 240 250
pF1KE1 IIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIV
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE1 CMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVY
::.::::::::: ::::::::::::::::::::::: .:::::.::::::::::::::::
XP_011 CMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVY
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE1 RDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWF
:::::::::::::::.::::::::::::::::::::::::::::::::::.:::::::::
XP_011 RDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWF
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE1 SLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNR
:::::::::::::::::::::::::::::::::. :::::.:::::.:::::::::::..
XP_011 SLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSK
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE1 RLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKG
:::: : :.::::: ::...::: :.:::::::::::::::::::::::::::::::::
XP_011 RLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKG
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE1 IKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYAL
::::: :::::.::::.:::::::::.:::....::.::..::::.::::::::::::::
XP_011 IKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYAL
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE1 GKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIK
:::::::::: :.:::::::::::::::::::::::::::. :.:::::.: ::::::::
XP_011 GKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIK
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE1 ERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVEL
..::.:..:.:::::.:::.::::.::::::: ....:::.:..:.::. ::::: .:::
XP_011 DKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRSGTVEL
460 470 480 490 500 510
680
pF1KE1 SKVPLVQRGSANGL
: : .:.: :::
XP_011 PKPSLCHRNS-NGL
520
>>NP_001004105 (OMIM: 600869) G protein-coupled receptor (560 aa)
initn: 851 init1: 336 opt: 1108 Z-score: 460.7 bits: 95.4 E(85289): 6.4e-19
Smith-Waterman score: 1108; 38.6% identity (64.6% similar) in 539 aa overlap (3-530:2-525)
10 20 30 40 50
pF1KE1 MADLEAVLADVSYLMAMEKSKATPAARASK-KILLPEPSIRSV--MQKYLEDRGEVTFEK
.:: ..:.. : : : . .. ....: . .: : : . .. :: . :.
NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCER
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 IFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKEL
: .: ::::.:: .. : .: : : . . .:: . ...: : .:.. .... .
NP_001 ---QPIGRLLFREFCATRPELSR-CVAFLDGVAEYE-VTPDDKRKACGRQLTQNFLSHTG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LACSHPFSKSATEHVQGHLGKKQVP-PDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQ
.. . . .: .: : :::: . . : : ...: :.:: :
NP_001 PDLIPEVPRQLVTNCTQRL--EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 WKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLA
:: .: . .: : : .:..:.:::::: .:. :::::: : :.::::: ..::..:
NP_001 WKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 LNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHLSQHGVFSEAD
:::. .: :.. :.: ..::..: : : ..: :::::::. ::..: : : ::
NP_001 LNEKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG-FPEAR
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 MRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKP-HASVG
:::::: ::: .: . .::::::: :::::.:::.:::::::: . . .. ::
NP_001 AVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 THGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTMAV
: :::::::. :. : : ::..:::.:.... :.:::.:.: : :.: ..:.. .
NP_001 TVGYMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPE
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 ELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLI
: . :::. ::: :: .: .:::: : .:.:::: :.:..:... . ::.
NP_001 EYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFK
410 420 430 440 450 460
480 490 500 510 520
pF1KE1 PPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET-VFDTI
: . :..:: .:. .::..: .::..:..: .. ::.:..:: :. .
NP_001 PDPQAIYCKDVLDIEQFST--VKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQEL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE1 NAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLE
:
NP_001 NVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQR
530 540 550 560
>>NP_001004106 (OMIM: 600869) G protein-coupled receptor (576 aa)
initn: 851 init1: 336 opt: 1108 Z-score: 460.6 bits: 95.4 E(85289): 6.4e-19
Smith-Waterman score: 1108; 38.6% identity (64.6% similar) in 539 aa overlap (3-530:2-525)
10 20 30 40 50
pF1KE1 MADLEAVLADVSYLMAMEKSKATPAARASK-KILLPEPSIRSV--MQKYLEDRGEVTFEK
.:: ..:.. : : : . .. ....: . .: : : . .. :: . :.
NP_001 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCER
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 IFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKEL
: .: ::::.:: .. : .: : : . . .:: . ...: : .:.. .... .
NP_001 ---QPIGRLLFREFCATRPELSR-CVAFLDGVAEYE-VTPDDKRKACGRQLTQNFLSHTG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LACSHPFSKSATEHVQGHLGKKQVP-PDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQ
.. . . .: .: : :::: . . : : ...: :.:: :
NP_001 PDLIPEVPRQLVTNCTQRL--EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 WKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLA
:: .: . .: : : .:..:.:::::: .:. :::::: : :.::::: ..::..:
NP_001 WKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 LNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHLSQHGVFSEAD
:::. .: :.. :.: ..::..: : : ..: :::::::. ::..: : : ::
NP_001 LNEKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG-FPEAR
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 MRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKP-HASVG
:::::: ::: .: . .::::::: :::::.:::.:::::::: . . .. ::
NP_001 AVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 THGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTMAV
: :::::::. :. : : ::..:::.:.... :.:::.:.: : :.: ..:.. .
NP_001 TVGYMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPE
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 ELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLI
: . :::. ::: :: .: .:::: : .:.:::: :.:..:... . ::.
NP_001 EYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFK
410 420 430 440 450 460
480 490 500 510 520
pF1KE1 PPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET-VFDTI
: . :..:: .:. .::..: .::..:..: .. ::.:..:: :. .
NP_001 PDPQAIYCKDVLDIEQFST--VKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQEL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE1 NAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLE
:
NP_001 NVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL
530 540 550 560 570
>>NP_002073 (OMIM: 600869) G protein-coupled receptor ki (589 aa)
initn: 851 init1: 336 opt: 1108 Z-score: 460.5 bits: 95.4 E(85289): 6.5e-19
Smith-Waterman score: 1108; 38.6% identity (64.6% similar) in 539 aa overlap (3-530:2-525)
10 20 30 40 50
pF1KE1 MADLEAVLADVSYLMAMEKSKATPAARASK-KILLPEPSIRSV--MQKYLEDRGEVTFEK
.:: ..:.. : : : . .. ....: . .: : : . .. :: . :.
NP_002 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCER
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 IFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKEL
: .: ::::.:: .. : .: : : . . .:: . ...: : .:.. .... .
NP_002 ---QPIGRLLFREFCATRPELSR-CVAFLDGVAEYE-VTPDDKRKACGRQLTQNFLSHTG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LACSHPFSKSATEHVQGHLGKKQVP-PDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQ
.. . . .: .: : :::: . . : : ...: :.:: :
NP_002 PDLIPEVPRQLVTNCTQRL--EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 WKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLA
:: .: . .: : : .:..:.:::::: .:. :::::: : :.::::: ..::..:
NP_002 WKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 LNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHLSQHGVFSEAD
:::. .: :.. :.: ..::..: : : ..: :::::::. ::..: : : ::
NP_002 LNEKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG-FPEAR
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 MRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKP-HASVG
:::::: ::: .: . .::::::: :::::.:::.:::::::: . . .. ::
NP_002 AVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 THGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTMAV
: :::::::. :. : : ::..:::.:.... :.:::.:.: : :.: ..:.. .
NP_002 TVGYMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPE
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 ELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLI
: . :::. ::: :: .: .:::: : .:.:::: :.:..:... . ::.
NP_002 EYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFK
410 420 430 440 450 460
480 490 500 510 520
pF1KE1 PPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET-VFDTI
: . :..:: .:. .::..: .::..:..: .. ::.:..:: :. .
NP_002 PDPQAIYCKDVLDIEQFST--VKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQEL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE1 NAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLE
:
NP_002 NVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAP
530 540 550 560 570 580
>>XP_006714922 (OMIM: 600869) PREDICTED: G protein-coupl (557 aa)
initn: 851 init1: 336 opt: 1092 Z-score: 454.6 bits: 94.2 E(85289): 1.4e-18
Smith-Waterman score: 1092; 40.8% identity (66.1% similar) in 478 aa overlap (61-530:28-493)
40 50 60 70 80 90
pF1KE1 KILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIK
: .: ::::.:: .. : .: : : . .
XP_006 MLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELSR-CVAFLDGVA
10 20 30 40 50
100 110 120 130 140
pF1KE1 KYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVP-PDLFQPY
.:: . ...: : .:.. .... . .. . . .: .: : ::::
XP_006 EYE-VTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRL--EQGPCKDLFQEL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE1 IEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCR
. . : : ...: :.:: ::: .: . .: : : .:..:.:::::: .:.
XP_006 TRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQ
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE1 KADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSF
:::::: : :.::::: ..::..::::. .: :.. :.: ..::..: : : .
XP_006 VRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR---FVVSLAYAYETKDALCL
180 190 200 210 220
270 280 290 300 310 320
pF1KE1 ILDLMNGGDLH---YHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLD
.: :::::::. ::..: : : :: :::::: ::: .: . .::::::: :::::
XP_006 VLTLMNGGDLKFHIYHMGQAG-FPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLD
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE1 EHGHVRISDLGLACDFSKKKP-HASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLL
.:::.:::::::: . . .. ::: :::::::. :. : : ::..:::.:....
XP_006 DHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVV-KNERYTFSPDWWALGCLLYEMI
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE1 RGHSPFRQHKTKDKHE-IDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGA
:.:::.:.: : :.: ..:.. . : . :::. ::: :: .: .:::: : .:
XP_006 AGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSA
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE1 QEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQE
.:::: :.:..:... . ::. : . :..:: .:. .::..: .::.
XP_006 REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFST--VKGVELEPTDQD
410 420 430 440 450 460
510 520 530 540 550 560
pF1KE1 LYRNFPL-TISERWQQEVAET-VFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMH
.:..: .. ::.:..:: :. .:
XP_006 FYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS
470 480 490 500 510 520
>>XP_006714921 (OMIM: 600869) PREDICTED: G protein-coupl (559 aa)
initn: 851 init1: 336 opt: 1092 Z-score: 454.6 bits: 94.3 E(85289): 1.4e-18
Smith-Waterman score: 1092; 40.8% identity (66.1% similar) in 478 aa overlap (61-530:30-495)
40 50 60 70 80 90
pF1KE1 KILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIK
: .: ::::.:: .. : .: : : . .
XP_006 MPHPCALGLWTQQLPSLPTERDYHSLCERQPIGRLLFREFCATRPELSR-CVAFLDGVA
10 20 30 40 50
100 110 120 130 140
pF1KE1 KYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVP-PDLFQPY
.:: . ...: : .:.. .... . .. . . .: .: : ::::
XP_006 EYE-VTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRL--EQGPCKDLFQEL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE1 IEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCR
. . : : ...: :.:: ::: .: . .: : : .:..:.:::::: .:.
XP_006 TRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQ
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE1 KADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSF
:::::: : :.::::: ..::..::::. .: :.. :.: ..::..: : : .
XP_006 VRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR---FVVSLAYAYETKDALCL
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE1 ILDLMNGGDLH---YHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLD
.: :::::::. ::..: : : :: :::::: ::: .: . .::::::: :::::
XP_006 VLTLMNGGDLKFHIYHMGQAG-FPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLD
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE1 EHGHVRISDLGLACDFSKKKP-HASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLL
.:::.:::::::: . . .. ::: :::::::. :. : : ::..:::.:....
XP_006 DHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVV-KNERYTFSPDWWALGCLLYEMI
300 310 320 330 340
390 400 410 420 430 440
pF1KE1 RGHSPFRQHKTKDKHE-IDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGA
:.:::.:.: : :.: ..:.. . : . :::. ::: :: .: .:::: : .:
XP_006 AGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSA
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE1 QEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQE
.:::: :.:..:... . ::. : . :..:: .:. .::..: .::.
XP_006 REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFST--VKGVELEPTDQD
410 420 430 440 450 460
510 520 530 540 550 560
pF1KE1 LYRNFPL-TISERWQQEVAET-VFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMH
.:..: .. ::.:..:: :. .:
XP_006 FYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFS
470 480 490 500 510 520
>>NP_005299 (OMIM: 600870) G protein-coupled receptor ki (590 aa)
initn: 792 init1: 299 opt: 1089 Z-score: 453.2 bits: 94.1 E(85289): 1.7e-18
Smith-Waterman score: 1089; 37.5% identity (65.4% similar) in 541 aa overlap (3-530:2-525)
10 20 30 40 50
pF1KE1 MADLEAVLADVSYLMAMEKSKATPAARASK-KILLPEPSIRSVMQ-KYLEDRGEVTFEKI
.:: ..:.. : : : . . ....: : .: : : . . . :: ..
NP_005 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCD-
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 FSQKLGYLLFRDFCLNHLEEARP----LVEFYEEIKKYEKLETEEERVARSREIFDSYIM
.: .: ::::.:: :.:: ..: . . .:: . .:. ...::. .:.
NP_005 -KQPIGRLLFRQFC-----ETRPGLECYIQFLDSVAEYE-VTPDEKLGEKGKEIMTKYLT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 KELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRF
. . ... . ... .: .: .::. . . . :::. :.....: : ::
NP_005 PKSPVFIAQVGQDLVSQTEEKLLQKPCK-ELFSACAQSVHEYLRGEPFHEYLDSMFFDRF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGET
::: .: . .: : : .:..:.:::::: .:. :::::: : :.::::: ..::.
NP_005 LQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGES
180 190 200 210 220
240 250 260 270 280 290
pF1KE1 LALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGV--FSEA
.::::. .: :.. :.: ..::..: : : ..: .::::::..:. . : : :
NP_005 MALNEKQILEKVNS---QFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 DMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKK-PHASV
::::::. ::: .: . .::::::: :::::..::.:::::::: . . .. :
NP_005 RALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTMA
:: ::::::::.. : : :...:::.......:.:::: .: : :.: .:: .:
NP_005 GTVGYMAPEVLNNQ-RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 VELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPL
.:: : .:. . :: .:...:::: .:: :::. ::::..... . ::.
NP_005 EVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPF
410 420 430 440 450 460
480 490 500 510 520
pF1KE1 IP-PRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET-VFD
.: ::. : :..:: .:. .::..: .:...: .: ..: ::.:. :: :
NP_005 VPDPRA-VYCKDVLDIEQFST--VKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFK
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE1 TINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNR
.:
NP_005 ELNVFGPNGTLPPDLNRNHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHV
530 540 550 560 570 580
689 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:44:38 2016 done: Sun Nov 6 23:44:40 2016
Total Scan time: 12.140 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]