Result of FASTA (omim) for
pFN21AE1366
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1366, 297 aa
1>>>pF1KE1366 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8557+/-0.000324; mu= 14.1195+/- 0.020
mean_var=87.4836+/-17.416, 0's: 0 Z-trim(117.1): 38 B-trim: 516 in 2/48
Lambda= 0.137123
statistics sampled from 28706 (28745) to 28706 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.337), width: 16
Scan time: 7.860
The best scores are: opt bits E(85289)
NP_690605 (OMIM: 112210,613495) B-lymphocyte antig ( 297) 1946 394.4 1.4e-109
NP_068769 (OMIM: 112210,613495) B-lymphocyte antig ( 297) 1946 394.4 1.4e-109
NP_113645 (OMIM: 606549) membrane-spanning 4-domai ( 250) 244 57.7 2.8e-08
XP_011543419 (OMIM: 606550) PREDICTED: membrane-sp ( 267) 237 56.3 7.6e-08
NP_060186 (OMIM: 606550) membrane-spanning 4-domai ( 267) 237 56.3 7.6e-08
XP_016873398 (OMIM: 606547) PREDICTED: membrane-sp ( 220) 227 54.3 2.6e-07
NP_076926 (OMIM: 606547) membrane-spanning 4-domai ( 220) 227 54.3 2.6e-07
NP_683876 (OMIM: 606547) membrane-spanning 4-domai ( 239) 227 54.3 2.8e-07
NP_076434 (OMIM: 606499) membrane-spanning 4-domai ( 200) 202 49.3 7.4e-06
NP_001230195 (OMIM: 606547) membrane-spanning 4-do ( 186) 184 45.7 8.2e-05
NP_996776 (OMIM: 608403) membrane-spanning 4-domai ( 267) 181 45.2 0.00017
XP_011543291 (OMIM: 608403) PREDICTED: membrane-sp ( 290) 181 45.2 0.00018
NP_071744 (OMIM: 606548) membrane-spanning 4-domai ( 225) 172 43.4 0.00049
NP_690591 (OMIM: 606548) membrane-spanning 4-domai ( 248) 172 43.4 0.00054
NP_001234928 (OMIM: 606548) membrane-spanning 4-do ( 253) 172 43.4 0.00054
NP_001317204 (OMIM: 606548) membrane-spanning 4-do ( 276) 172 43.4 0.00058
XP_005274234 (OMIM: 606548) PREDICTED: membrane-sp ( 276) 172 43.4 0.00058
NP_690590 (OMIM: 606548) membrane-spanning 4-domai ( 178) 160 40.9 0.0021
NP_067024 (OMIM: 606502) membrane-spanning 4-domai ( 240) 155 40.0 0.0054
NP_996822 (OMIM: 606502) membrane-spanning 4-domai ( 240) 155 40.0 0.0054
>>NP_690605 (OMIM: 112210,613495) B-lymphocyte antigen C (297 aa)
initn: 1946 init1: 1946 opt: 1946 Z-score: 2088.3 bits: 394.4 E(85289): 1.4e-109
Smith-Waterman score: 1946; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KE1 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 SLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 QYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTI
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 EIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 EIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
250 260 270 280 290
>>NP_068769 (OMIM: 112210,613495) B-lymphocyte antigen C (297 aa)
initn: 1946 init1: 1946 opt: 1946 Z-score: 2088.3 bits: 394.4 E(85289): 1.4e-109
Smith-Waterman score: 1946; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KE1 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTI
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 EIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
250 260 270 280 290
>>NP_113645 (OMIM: 606549) membrane-spanning 4-domains s (250 aa)
initn: 204 init1: 87 opt: 244 Z-score: 269.7 bits: 57.7 E(85289): 2.8e-08
Smith-Waterman score: 244; 36.9% identity (66.9% similar) in 130 aa overlap (13-138:34-160)
10 20 30 40
pF1KE1 MTTPRNSVNGTFPAEPMKGP-IAMQSGPKPLFRRMSSLVG-P
: : . : . . : : . .:.. : :
NP_113 MTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSL--VSNVNGQP
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 TQSFFMRESKTLGAVQIMNGLFHIALGGLLM-IPAGIYAPICVTVWYPLWGGIMYIISGS
.:. ..:.:::::.::. :: ::.::... . .: : : .:.:::. .:::::
NP_113 VQKA-LKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 LLAATEKNSRK-CLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAH
: .:.:.. . ::..:.. .: .: . . :.:: : :.
NP_113 LSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 TPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKR
NP_113 GMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPP
190 200 210 220 230 240
>>XP_011543419 (OMIM: 606550) PREDICTED: membrane-spanni (267 aa)
initn: 290 init1: 168 opt: 237 Z-score: 261.8 bits: 56.3 E(85289): 7.6e-08
Smith-Waterman score: 243; 36.4% identity (67.1% similar) in 143 aa overlap (6-138:41-183)
10 20 30
pF1KE1 MTTPRNSVNGTFPAEP--MKGP-IAMQSGP-KPLF
:...:. :.: . .: : .: : . .
XP_011 EVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIFASSQPGQGNI
20 30 40 50 60 70
40 50 60 70 80
pF1KE1 RRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLL-MIPAGI-----YAPICVTVW
. .. :: . : .:.:.::..::: ::.::..: .: .: .. .: :
XP_011 QMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGG
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 YPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISH
::.:::. .:::::: ... :. .:::::.. :: .: . :. :.:: ..:.
XP_011 YPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAG
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQE
XP_011 QDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPNMYESNPVTPA
200 210 220 230 240 250
>>NP_060186 (OMIM: 606550) membrane-spanning 4-domains s (267 aa)
initn: 290 init1: 168 opt: 237 Z-score: 261.8 bits: 56.3 E(85289): 7.6e-08
Smith-Waterman score: 243; 36.4% identity (67.1% similar) in 143 aa overlap (6-138:41-183)
10 20 30
pF1KE1 MTTPRNSVNGTFPAEP--MKGP-IAMQSGP-KPLF
:...:. :.: . .: : .: : . .
NP_060 EVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIFASSQPGQGNI
20 30 40 50 60 70
40 50 60 70 80
pF1KE1 RRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLL-MIPAGI-----YAPICVTVW
. .. :: . : .:.:.::..::: ::.::..: .: .: .. .: :
NP_060 QMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGG
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 YPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISH
::.:::. .:::::: ... :. .:::::.. :: .: . :. :.:: ..:.
NP_060 YPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAG
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQE
NP_060 QDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPNMYESNPVTPA
200 210 220 230 240 250
>>XP_016873398 (OMIM: 606547) PREDICTED: membrane-spanni (220 aa)
initn: 223 init1: 150 opt: 227 Z-score: 252.3 bits: 54.3 E(85289): 2.6e-07
Smith-Waterman score: 264; 26.6% identity (55.7% similar) in 237 aa overlap (7-239:3-211)
10 20 30 40 50
pF1KE1 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMR-ESKTLGAVQIMN
...: : : :: . : : ... : : : :.. : :.::.:::..
XP_016 MTTMQGMEQAMPGAGPGVPQLGNMAVIH--SHLWKGLQEKFLKGEPKVLGVVQILT
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 GLFHIALGGLLM-IPAGIYA--PICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGK
.:. ...: .: . .. :. :: : . : .::..:.:::::: :. . : ::.:.
XP_016 ALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 MIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKN
. :: : : ::.... . :: : : :: : :.
XP_016 LGMNITSSVLAASGILINTF--------------SLAFYSFHHPYCNYYG----------
120 130 140 150
180 190 200 210 220 230
pF1KE1 SPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKK
... :.. .:...:. ...:... .. . ... : : : . ...: .. .
XP_016 --NSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHM
160 170 180 190 200
240 250 260 270 280 290
pF1KE1 EQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSS
.:
XP_016 AETASPTPLNEV
210 220
>>NP_076926 (OMIM: 606547) membrane-spanning 4-domains s (220 aa)
initn: 223 init1: 150 opt: 227 Z-score: 252.3 bits: 54.3 E(85289): 2.6e-07
Smith-Waterman score: 264; 26.6% identity (55.7% similar) in 237 aa overlap (7-239:3-211)
10 20 30 40 50
pF1KE1 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMR-ESKTLGAVQIMN
...: : : :: . : : ... : : : :.. : :.::.:::..
NP_076 MTTMQGMEQAMPGAGPGVPQLGNMAVIH--SHLWKGLQEKFLKGEPKVLGVVQILT
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 GLFHIALGGLLM-IPAGIYA--PICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGK
.:. ...: .: . .. :. :: : . : .::..:.:::::: :. . : ::.:.
NP_076 ALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 MIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKN
. :: : : ::.... . :: : : :: : :.
NP_076 LGMNITSSVLAASGILINTF--------------SLAFYSFHHPYCNYYG----------
120 130 140 150
180 190 200 210 220 230
pF1KE1 SPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKK
... :.. .:...:. ...:... .. . ... : : : . ...: .. .
NP_076 --NSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHM
160 170 180 190 200
240 250 260 270 280 290
pF1KE1 EQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSS
.:
NP_076 AETASPTPLNEV
210 220
>>NP_683876 (OMIM: 606547) membrane-spanning 4-domains s (239 aa)
initn: 223 init1: 150 opt: 227 Z-score: 251.8 bits: 54.3 E(85289): 2.8e-07
Smith-Waterman score: 264; 26.6% identity (55.7% similar) in 237 aa overlap (7-239:22-230)
10 20 30 40
pF1KE1 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFF
...: : : :: . : : ... : : : :
NP_683 MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIH--SHLWKGLQEKF
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 MR-ESKTLGAVQIMNGLFHIALGGLLM-IPAGIYA--PICVTVWYPLWGGIMYIISGSLL
.. : :.::.:::...:. ...: .: . .. :. :: : . : .::..:.::::::
NP_683 LKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 AATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPY
:. . : ::.:.. :: : : ::.... . :: : : ::
NP_683 IAAGIRTTKGLVRGSLGMNITSSVLAASGILINTF--------------SLAFYSFHHPY
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 INIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCS
: :. ... :.. .:...:. ...:... .. . ... : :
NP_683 CNYYG------------NSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCC
170 180 190 200 210
230 240 250 260 270 280
pF1KE1 RPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPE
: . ...: .. . .:
NP_683 TPGGVVLILPSHSHMAETASPTPLNEV
220 230
>>NP_076434 (OMIM: 606499) membrane-spanning 4-domains s (200 aa)
initn: 240 init1: 140 opt: 202 Z-score: 226.2 bits: 49.3 E(85289): 7.4e-06
Smith-Waterman score: 212; 28.4% identity (59.1% similar) in 176 aa overlap (36-207:34-180)
10 20 30 40 50 60
pF1KE1 NSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIA
: .: :..: :. : ::..::. :.. ..
NP_076 STAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LGGL----LMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNS
.: . :. : . :. ::.::....: ::..: :..... . :. . :::
NP_076 FGVIFLFTLLKPYPRF-PFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQ
:: ..::.:.:: ...:: .. : : . :..::
NP_076 LSALGAIAGIILL----------------TFGFILDQN-----YIC---GYSHQNSQ---
130 140 150
190 200 210 220 230 240
pF1KE1 YCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIE
: .. :::::: ... :.... ..
NP_076 -CKAVTVLFLGILITLMTFSIIELFISLPFSILGCHSEDCDCEQCC
160 170 180 190 200
>>NP_001230195 (OMIM: 606547) membrane-spanning 4-domain (186 aa)
initn: 136 init1: 99 opt: 184 Z-score: 207.4 bits: 45.7 E(85289): 8.2e-05
Smith-Waterman score: 184; 32.6% identity (62.8% similar) in 129 aa overlap (7-129:22-148)
10 20 30 40
pF1KE1 MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFF
...: : : :: . : : ... : : : :
NP_001 MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIH--SHLWKGLQEKF
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 MR-ESKTLGAVQIMNGLFHIALGGLLM-IPAGIYA--PICVTVWYPLWGGIMYIISGSL-
.. : :.::.:::...:. ...: .: . .. :. :: : . : .::..:.::::::
NP_001 LKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLS
60 70 80 90 100 110
110 120 130 140 150
pF1KE1 LAATEKNSRKCLVKGKMIMNSLSLFA-AISGMILSIMDILNIKISHFLKMESLNFIRAHT
.:: .... . : ... :. : :.:
NP_001 IAAGIRTTKGLGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETA
120 130 140 150 160 170
297 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:23:34 2016 done: Sun Nov 6 23:23:35 2016
Total Scan time: 7.860 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]