Result of FASTA (ccds) for
pFN21AE1363
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1363, 585 aa
1>>>pF1KE1363 585 - 585 aa - 585 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7460+/-0.000911; mu= 8.8608+/- 0.055
mean_var=148.0087+/-29.609, 0's: 0 Z-trim(110.1): 18 B-trim: 40 in 1/52
Lambda= 0.105422
statistics sampled from 11351 (11359) to 11351 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.349), width: 16
Scan time: 3.680
The best scores are: opt bits E(32554)
CCDS46935.1 EIF2A gene_id:83939|Hs108|chr3 ( 585) 3956 613.6 2.2e-175
CCDS82860.1 EIF2A gene_id:83939|Hs108|chr3 ( 580) 3904 605.6 5.3e-173
CCDS82861.1 EIF2A gene_id:83939|Hs108|chr3 ( 560) 3552 552.1 6.7e-157
CCDS82859.1 EIF2A gene_id:83939|Hs108|chr3 ( 524) 2862 447.1 2.5e-125
>>CCDS46935.1 EIF2A gene_id:83939|Hs108|chr3 (585 aa)
initn: 3956 init1: 3956 opt: 3956 Z-score: 3262.1 bits: 613.6 E(32554): 2.2e-175
Smith-Waterman score: 3956; 99.8% identity (100.0% similar) in 585 aa overlap (1-585:1-585)
10 20 30 40 50 60
pF1KE1 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
490 500 510 520 530 540
550 560 570 580
pF1KE1 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLKLGI
:::::::::::::::::::::::::::::::::::::::::.:::
CCDS46 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI
550 560 570 580
>>CCDS82860.1 EIF2A gene_id:83939|Hs108|chr3 (580 aa)
initn: 3523 init1: 3523 opt: 3904 Z-score: 3219.4 bits: 605.6 E(32554): 5.3e-173
Smith-Waterman score: 3904; 98.8% identity (99.1% similar) in 585 aa overlap (1-585:1-580)
10 20 30 40 50 60
pF1KE1 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGE---
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 --NVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE1 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE1 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
480 490 500 510 520 530
550 560 570 580
pF1KE1 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLKLGI
:::::::::::::::::::::::::::::::::::::::::.:::
CCDS82 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI
540 550 560 570 580
>>CCDS82861.1 EIF2A gene_id:83939|Hs108|chr3 (560 aa)
initn: 3552 init1: 3552 opt: 3552 Z-score: 2930.3 bits: 552.1 E(32554): 6.7e-157
Smith-Waterman score: 3714; 95.6% identity (95.7% similar) in 585 aa overlap (1-585:1-560)
10 20 30 40 50 60
pF1KE1 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
::::::::::::::::::::::::::::::::: ::
CCDS82 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPR-------------------------VN
10 20 30
70 80 90 100 110 120
pF1KE1 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
460 470 480 490 500 510
550 560 570 580
pF1KE1 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLKLGI
:::::::::::::::::::::::::::::::::::::::::.:::
CCDS82 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI
520 530 540 550 560
>>CCDS82859.1 EIF2A gene_id:83939|Hs108|chr3 (524 aa)
initn: 2862 init1: 2862 opt: 2862 Z-score: 2363.5 bits: 447.1 E(32554): 2.5e-125
Smith-Waterman score: 3392; 89.4% identity (89.6% similar) in 585 aa overlap (1-585:1-524)
10 20 30 40 50 60
pF1KE1 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
:::::::::::::::::::::::::::::::::::::
CCDS82 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYT-----------------------
70 80 90
130 140 150 160 170 180
pF1KE1 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
::::::::::::::::::::::
CCDS82 --------------------------------------NTIANKLHLQKINDFVLSPGPQ
100 110
190 200 210 220 230 240
pF1KE1 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE1 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE1 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE1 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE1 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE1 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
420 430 440 450 460 470
550 560 570 580
pF1KE1 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLKLGI
:::::::::::::::::::::::::::::::::::::::::.:::
CCDS82 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI
480 490 500 510 520
585 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:48:07 2016 done: Mon Nov 7 01:48:07 2016
Total Scan time: 3.680 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]