FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1362, 312 aa
  1>>>pF1KE1362 312 - 312 aa - 312 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.1235+/-0.000287; mu= 4.9605+/- 0.018
 mean_var=189.8847+/-38.623, 0's: 0 Z-trim(123.5): 4  B-trim: 0 in 0/61
 Lambda= 0.093074
 statistics sampled from 43456 (43460) to 43456 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.813), E-opt: 0.2 (0.51), width:  16
 Scan time:  8.860

The best scores are:                                      opt bits E(85289)
XP_016879304 (OMIM: 603500) PREDICTED: tumor necro ( 312) 2065 288.7   1e-77
NP_001310481 (OMIM: 603500) tumor necrosis factor  ( 312) 2065 288.7   1e-77
NP_003780 (OMIM: 603500) tumor necrosis factor rec ( 312) 2065 288.7   1e-77
XP_005256270 (OMIM: 603500) PREDICTED: tumor necro ( 252) 1677 236.6 4.1e-62


>>XP_016879304 (OMIM: 603500) PREDICTED: tumor necrosis   (312 aa)
 initn: 2065 init1: 2065 opt: 2065  Z-score: 1516.4  bits: 288.7 E(85289): 1e-77
Smith-Waterman score: 2065; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)

               10        20        30        40        50        60
pF1KE1 MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
              250       260       270       280       290       300

              310  
pF1KE1 LLGLTDPNGGLA
       ::::::::::::
XP_016 LLGLTDPNGGLA
              310  

>>NP_001310481 (OMIM: 603500) tumor necrosis factor rece  (312 aa)
 initn: 2065 init1: 2065 opt: 2065  Z-score: 1516.4  bits: 288.7 E(85289): 1e-77
Smith-Waterman score: 2065; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)

               10        20        30        40        50        60
pF1KE1 MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
              250       260       270       280       290       300

              310  
pF1KE1 LLGLTDPNGGLA
       ::::::::::::
NP_001 LLGLTDPNGGLA
              310  

>>NP_003780 (OMIM: 603500) tumor necrosis factor recepto  (312 aa)
 initn: 2065 init1: 2065 opt: 2065  Z-score: 1516.4  bits: 288.7 E(85289): 1e-77
Smith-Waterman score: 2065; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)

               10        20        30        40        50        60
pF1KE1 MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
              250       260       270       280       290       300

              310  
pF1KE1 LLGLTDPNGGLA
       ::::::::::::
NP_003 LLGLTDPNGGLA
              310  

>>XP_005256270 (OMIM: 603500) PREDICTED: tumor necrosis   (252 aa)
 initn: 1677 init1: 1677 opt: 1677  Z-score: 1236.1  bits: 236.6 E(85289): 4.1e-62
Smith-Waterman score: 1677; 100.0% identity (100.0% similar) in 252 aa overlap (61-312:1-252)

               40        50        60        70        80        90
pF1KE1 AYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAY
                                     ::::::::::::::::::::::::::::::
XP_005                               MLKIHRSDPQLIVQLRFCGRQPCGRFLRAY
                                             10        20        30

              100       110       120       130       140       150
pF1KE1 REGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REGALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDE
               40        50        60        70        80        90

              160       170       180       190       200       210
pF1KE1 ELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVV
              100       110       120       130       140       150

              220       230       240       250       260       270
pF1KE1 NRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLR
              160       170       180       190       200       210

              280       290       300       310  
pF1KE1 RFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA
       ::::::::::::::::::::::::::::::::::::::::::
XP_005 RFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA
              220       230       240       250  




312 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 02:25:40 2016 done: Mon Nov  7 02:25:42 2016
 Total Scan time:  8.860 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]