Result of FASTA (omim) for
pFN21AE1353
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1353, 207 aa
1>>>pF1KE1353 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5967+/-0.000327; mu= -4.1029+/- 0.020
mean_var=251.0693+/-50.971, 0's: 0 Z-trim(124.2): 37 B-trim: 342 in 1/56
Lambda= 0.080943
statistics sampled from 45279 (45316) to 45279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.823), E-opt: 0.2 (0.531), width: 16
Scan time: 6.870
The best scores are: opt bits E(85289)
NP_003368 (OMIM: 601398) vascular endothelial grow ( 207) 1435 179.2 4.1e-45
NP_001230662 (OMIM: 601398) vascular endothelial g ( 188) 970 124.9 8.5e-29
NP_001165094 (OMIM: 192240,603933) vascular endoth ( 232) 380 56.0 5.5e-08
NP_001165095 (OMIM: 192240,603933) vascular endoth ( 215) 375 55.4 7.8e-08
NP_001191313 (OMIM: 192240,603933) vascular endoth ( 171) 372 55.0 8.3e-08
NP_001020537 (OMIM: 192240,603933) vascular endoth ( 412) 380 56.2 8.6e-08
NP_001165096 (OMIM: 192240,603933) vascular endoth ( 209) 373 55.2 8.9e-08
NP_003367 (OMIM: 192240,603933) vascular endotheli ( 395) 375 55.6 1.2e-07
NP_001165099 (OMIM: 192240,603933) vascular endoth ( 147) 364 54.0 1.4e-07
NP_001020538 (OMIM: 192240,603933) vascular endoth ( 389) 373 55.4 1.4e-07
NP_001191314 (OMIM: 192240,603933) vascular endoth ( 351) 372 55.2 1.5e-07
NP_001165098 (OMIM: 192240,603933) vascular endoth ( 174) 362 53.9 1.9e-07
NP_001165100 (OMIM: 192240,603933) vascular endoth ( 191) 362 53.9 2e-07
NP_001165097 (OMIM: 192240,603933) vascular endoth ( 191) 362 53.9 2e-07
NP_001303939 (OMIM: 192240,603933) vascular endoth ( 213) 362 53.9 2.2e-07
NP_001020541 (OMIM: 192240,603933) vascular endoth ( 327) 364 54.3 2.6e-07
NP_001020540 (OMIM: 192240,603933) vascular endoth ( 354) 362 54.1 3.3e-07
NP_001020539 (OMIM: 192240,603933) vascular endoth ( 371) 362 54.1 3.4e-07
NP_001028928 (OMIM: 192240,603933) vascular endoth ( 371) 362 54.1 3.4e-07
NP_001165101 (OMIM: 192240,603933) vascular endoth ( 137) 341 51.3 8.6e-07
NP_001273973 (OMIM: 192240,603933) vascular endoth ( 163) 342 51.5 9.1e-07
NP_001165093 (OMIM: 192240,603933) vascular endoth ( 317) 341 51.6 1.6e-06
NP_001280572 (OMIM: 601121) placenta growth factor ( 169) 280 44.3 0.00014
NP_002623 (OMIM: 601121) placenta growth factor is ( 170) 278 44.0 0.00017
NP_001193941 (OMIM: 601121) placenta growth factor ( 149) 274 43.5 0.00021
>>NP_003368 (OMIM: 601398) vascular endothelial growth f (207 aa)
initn: 1435 init1: 1435 opt: 1435 Z-score: 930.9 bits: 179.2 E(85289): 4.1e-45
Smith-Waterman score: 1435; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAP
130 140 150 160 170 180
190 200
pF1KE1 STTSALTPGPAAAAADAAASSVAKGGA
:::::::::::::::::::::::::::
NP_003 STTSALTPGPAAAAADAAASSVAKGGA
190 200
>>NP_001230662 (OMIM: 601398) vascular endothelial growt (188 aa)
initn: 966 init1: 944 opt: 970 Z-score: 638.0 bits: 124.9 E(85289): 8.5e-29
Smith-Waterman score: 970; 91.7% identity (93.6% similar) in 156 aa overlap (1-149:1-156)
10 20 30 40 50 60
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QCECRPKKKDSAVKPD--RAATP-----HHRPQPRSVPGWDSAPGAPSPADITHPTPAPG
:::::::::::::::: : : :.::.::.
NP_001 QCECRPKKKDSAVKPDSPRPLCPRCTQHHQRPDPRTCRCRCRRRSFLRCQGRGLELNPDT
130 140 150 160 170 180
180 190 200
pF1KE1 PSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
NP_001 CRCRKLRR
>>NP_001165094 (OMIM: 192240,603933) vascular endothelia (232 aa)
initn: 254 init1: 254 opt: 380 Z-score: 264.4 bits: 56.0 E(85289): 5.5e-08
Smith-Waterman score: 380; 37.9% identity (61.6% similar) in 177 aa overlap (10-174:12-186)
10 20 30 40 50
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVVSWIDVYTRATCQPREVVVP
:: :: : :. . : : : ....::...::: :. :.: :..:
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQ-LGEM
. : . . :::: ..:::::: :.::::::: . .. :::. :. ..: .:::
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
120 130 140 150 160
pF1KE1 SLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRS-----VPGWDSAPGAPS---PADIT
:. .:..::::::: : : . ... . . : :. .:. :: : ..
NP_001 SFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSLP
130 140 150 160 170
170 180 190 200
pF1KE1 HPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
: : ::
NP_001 GPHPC-GPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
180 190 200 210 220 230
>>NP_001165095 (OMIM: 192240,603933) vascular endothelia (215 aa)
initn: 254 init1: 254 opt: 375 Z-score: 261.7 bits: 55.4 E(85289): 7.8e-08
Smith-Waterman score: 375; 39.4% identity (65.0% similar) in 160 aa overlap (10-160:12-169)
10 20 30 40 50
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVVSWIDVYTRATCQPREVVVP
:: :: : :. . : : : ....::...::: :. :.: :..:
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQ-LGEM
. : . . :::: ..:::::: :.::::::: . .. :::. :. ..: .:::
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
120 130 140 150 160
pF1KE1 SLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRS-----VPGWDSAPGAPSPADITHPT
:. .:..::::::: : : . ... . . : :. .: :.: .:
NP_001 SFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRKKSRYKSW-SVPCGPCSERRKHLF
130 140 150 160 170
170 180 190 200
pF1KE1 PAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
NP_001 VQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
180 190 200 210
>>NP_001191313 (OMIM: 192240,603933) vascular endothelia (171 aa)
initn: 254 init1: 254 opt: 372 Z-score: 261.2 bits: 55.0 E(85289): 8.3e-08
Smith-Waterman score: 372; 41.3% identity (67.1% similar) in 143 aa overlap (10-148:12-153)
10 20 30 40 50
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVVSWIDVYTRATCQPREVVVP
:: :: : :. . : : : ....::...::: :. :.: :..:
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQ-LGEM
. : . . :::: ..:::::: :.::::::: . .. :::. :. ..: .:::
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 SLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGP
:. .:..::::::: : : . ... . . : :
NP_001 SFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRKKSRYKSWSVCDKPRR
130 140 150 160 170
180 190 200
pF1KE1 SAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
>>NP_001020537 (OMIM: 192240,603933) vascular endothelia (412 aa)
initn: 254 init1: 254 opt: 380 Z-score: 260.9 bits: 56.2 E(85289): 8.6e-08
Smith-Waterman score: 380; 37.9% identity (61.6% similar) in 177 aa overlap (10-174:192-366)
10 20 30
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVV
:: :: : :. . : : : ....::
NP_001 SPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVV
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE1 SWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQ
...::: :. :.: :..: . : . . :::: ..:::::: :.::::::: . .
NP_001 KFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESN
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE1 VRMQILMIRYPSSQ-LGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRS-----V
. :::. :. ..: .::::. .:..::::::: : : . ... . . : :.
NP_001 ITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRKKSRY
290 300 310 320 330 340
160 170 180 190 200
pF1KE1 PGWDSAPGAPS---PADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
.:. :: : .. : : ::
NP_001 KSWSVYVGARCCLMPWSLPGPHPC-GPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLE
350 360 370 380 390
>>NP_001165096 (OMIM: 192240,603933) vascular endothelia (209 aa)
initn: 254 init1: 254 opt: 373 Z-score: 260.6 bits: 55.2 E(85289): 8.9e-08
Smith-Waterman score: 373; 40.0% identity (65.2% similar) in 155 aa overlap (10-160:12-163)
10 20 30 40 50
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVVSWIDVYTRATCQPREVVVP
:: :: : :. . : : : ....::...::: :. :.: :..:
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQ-LGEM
. : . . :::: ..:::::: :.::::::: . .. :::. :. ..: .:::
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 SLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGP
:. .:..::::::: : : . ... . . : :. : : .:
NP_001 SFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRK--KSRPCGPCSERRKHLFVQDPQ
130 140 150 160 170
180 190 200
pF1KE1 SAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
NP_001 TCKCSCKNTDSRCKARQLELNERTCRCDKPRR
180 190 200
>>NP_003367 (OMIM: 192240,603933) vascular endothelial g (395 aa)
initn: 254 init1: 254 opt: 375 Z-score: 258.0 bits: 55.6 E(85289): 1.2e-07
Smith-Waterman score: 375; 39.4% identity (65.0% similar) in 160 aa overlap (10-160:192-349)
10 20 30
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVV
:: :: : :. . : : : ....::
NP_003 SPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVV
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE1 SWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQ
...::: :. :.: :..: . : . . :::: ..:::::: :.::::::: . .
NP_003 KFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESN
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE1 VRMQILMIRYPSSQ-LGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRS-----V
. :::. :. ..: .::::. .:..::::::: : : . ... . . : :.
NP_003 ITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRKKSRY
290 300 310 320 330 340
160 170 180 190 200
pF1KE1 PGWDSAPGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
.: :.: .:
NP_003 KSW-SVPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
350 360 370 380 390
>>NP_001165099 (OMIM: 192240,603933) vascular endothelia (147 aa)
initn: 254 init1: 254 opt: 364 Z-score: 257.0 bits: 54.0 E(85289): 1.4e-07
Smith-Waterman score: 364; 42.6% identity (67.6% similar) in 136 aa overlap (10-137:12-147)
10 20 30 40 50
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVVSWIDVYTRATCQPREVVVP
:: :: : :. . : : : ....::...::: :. :.: :..:
NP_001 MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQ-LGEM
. : . . :::: ..:::::: :.::::::: . .. :::. :. ..: .:::
NP_001 IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 SLEEHSQCECRPKK----KDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTP
:. .:..::::::: ... :: :
NP_001 SFLQHNKCECRPKKDRARQEKCDKPRR
130 140
>>NP_001020538 (OMIM: 192240,603933) vascular endothelia (389 aa)
initn: 254 init1: 254 opt: 373 Z-score: 256.8 bits: 55.4 E(85289): 1.4e-07
Smith-Waterman score: 373; 40.0% identity (65.2% similar) in 155 aa overlap (10-160:192-343)
10 20 30
pF1KE1 MSPLLRRLLLAALLQLAPAQAPVSQPDAPG---HQRKVV
:: :: : :. . : : : ....::
NP_001 SPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVV
170 180 190 200 210 220
40 50 60 70 80 90
pF1KE1 SWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQ
...::: :. :.: :..: . : . . :::: ..:::::: :.::::::: . .
NP_001 KFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESN
230 240 250 260 270 280
100 110 120 130 140 150
pF1KE1 VRMQILMIRYPSSQ-LGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDS
. :::. :. ..: .::::. .:..::::::: : : . ... . . : :. :
NP_001 ITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKK-DRARQEKKSVRGKGKGQKRKRK--KS
290 300 310 320 330
160 170 180 190 200
pF1KE1 APGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
: .:
NP_001 RPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
340 350 360 370 380
207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:09:15 2016 done: Sun Nov 6 23:09:16 2016
Total Scan time: 6.870 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]