Result of FASTA (omim) for
pFN21AE1344
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1344, 560 aa
1>>>pF1KE1344 560 - 560 aa - 560 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6836+/-0.000365; mu= 12.7634+/- 0.023
mean_var=99.9060+/-19.984, 0's: 0 Z-trim(115.5): 25 B-trim: 0 in 0/54
Lambda= 0.128315
statistics sampled from 25926 (25949) to 25926 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.304), width: 16
Scan time: 11.140
The best scores are: opt bits E(85289)
NP_001245 (OMIM: 602627,613805) cell division cont ( 560) 3658 687.8 2.4e-197
XP_011523844 (OMIM: 602627,613805) PREDICTED: cell ( 600) 2634 498.2 3e-140
XP_011523843 (OMIM: 602627,613805) PREDICTED: cell ( 600) 2634 498.2 3e-140
NP_001177748 (OMIM: 224690,601902) origin recognit ( 856) 531 109.0 6.3e-23
XP_011539829 (OMIM: 224690,601902) PREDICTED: orig ( 501) 516 106.1 2.7e-22
XP_016856878 (OMIM: 224690,601902) PREDICTED: orig ( 615) 516 106.2 3.2e-22
NP_004144 (OMIM: 224690,601902) origin recognition ( 861) 516 106.2 4.3e-22
NP_001177747 (OMIM: 224690,601902) origin recognit ( 861) 516 106.2 4.3e-22
XP_016856877 (OMIM: 224690,601902) PREDICTED: orig ( 825) 206 48.8 7.9e-05
>>NP_001245 (OMIM: 602627,613805) cell division control (560 aa)
initn: 3658 init1: 3658 opt: 3658 Z-score: 3663.9 bits: 687.8 E(85289): 2.4e-197
Smith-Waterman score: 3658; 99.8% identity (100.0% similar) in 560 aa overlap (1-560:1-560)
10 20 30 40 50 60
pF1KE1 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEV
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_001 SEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 TLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKE
490 500 510 520 530 540
550 560
pF1KE1 IEHALKDKALIGNILATGLP
::::::::::::::::::::
NP_001 IEHALKDKALIGNILATGLP
550 560
>>XP_011523844 (OMIM: 602627,613805) PREDICTED: cell div (600 aa)
initn: 2633 init1: 2633 opt: 2634 Z-score: 2639.0 bits: 498.2 E(85289): 3e-140
Smith-Waterman score: 3518; 93.1% identity (93.2% similar) in 592 aa overlap (1-552:1-592)
10 20 30 40 50 60
pF1KE1 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
310 320 330 340 350 360
370 380 390
pF1KE1 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCR-------------------------
:::::::::::::::::::::::::::::::::::
XP_011 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRKEDLFLSGELWISTVLMSETLSVHY
370 380 390 400 410 420
400 410 420 430 440
pF1KE1 ---------------RAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISE
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQREKQMRCCWHSLWRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISE
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE1 IDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAA
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAA
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE1 VDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
550 560 570 580 590 600
>>XP_011523843 (OMIM: 602627,613805) PREDICTED: cell div (600 aa)
initn: 2633 init1: 2633 opt: 2634 Z-score: 2639.0 bits: 498.2 E(85289): 3e-140
Smith-Waterman score: 3518; 93.1% identity (93.2% similar) in 592 aa overlap (1-552:1-592)
10 20 30 40 50 60
pF1KE1 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN
310 320 330 340 350 360
370 380 390
pF1KE1 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCR-------------------------
:::::::::::::::::::::::::::::::::::
XP_011 QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRKEDLFLSGELWISTVLMSETLSVHY
370 380 390 400 410 420
400 410 420 430 440
pF1KE1 ---------------RAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISE
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQREKQMRCCWHSLWRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISE
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE1 IDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAA
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAA
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE1 VDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
550 560 570 580 590 600
>>NP_001177748 (OMIM: 224690,601902) origin recognition (856 aa)
initn: 353 init1: 167 opt: 531 Z-score: 532.6 bits: 109.0 E(85289): 6.3e-23
Smith-Waterman score: 613; 28.5% identity (63.1% similar) in 463 aa overlap (99-548:422-856)
70 80 90 100 110 120
pF1KE1 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
:.. . : :. .. . .. ::...:
NP_001 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
400 410 420 430 440 450
130 140 150 160 170 180
pF1KE1 EITTNSEQRCPLKKESACVR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREMDVIR
. :. . : : . . .: : :: .. ..:.: :. .:::. :: ::.:.. :
NP_001 HTLTKLKPRTP-RCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEFQDIY
460 470 480 490 500 510
190 200 210 220 230
pF1KE1 NFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCMSLRT
::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: :.:
NP_001 NFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTE
520 530 540 550 560 570
240 250 260 270 280 290
pF1KE1 AQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSKGQDV
. :. : :.. .... . .. : :.. .. .:. ::..::.: : .. ::.
NP_001 PHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTHKQDI
580 590 600 610 620
300 310 320 330 340 350
pF1KE1 LYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQIVTIL
.:.::.:: ....::...::::.:: .::. :...: . : ::: .:. ::
NP_001 MYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQLQQIL
630 640 650 660 670 680
360 370 380 390 400 410
pF1KE1 QDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLS
..::... ..... :.:. ::::.:.:::.:. ::.:::: :: : ::
NP_001 RSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ-------
690 700 710 720 730
420 430 440 450 460 470
pF1KE1 ECKSPSEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQL
..:. : ::. :.. . .: . . ..: :.:..: ... .:.
NP_001 --QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAEFRRS
740 750 760 770 780
480 490 500 510 520 530
pF1KE1 KIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFK
..:.:. ..: . .:: . . .:: ... . : . .: .. ... : .: ..
NP_001 GLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLN
790 800 810 820 830 840
540 550 560
pF1KE1 IEEKEIEHALKDKALIGNILATGLP
. . .. .::::.
NP_001 VSQDDVLYALKDE
850
>>XP_011539829 (OMIM: 224690,601902) PREDICTED: origin r (501 aa)
initn: 404 init1: 167 opt: 516 Z-score: 521.2 bits: 106.1 E(85289): 2.7e-22
Smith-Waterman score: 603; 28.1% identity (62.3% similar) in 467 aa overlap (99-548:62-501)
70 80 90 100 110 120
pF1KE1 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
:.. . : :. .. . .. ::...:
XP_011 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM
. :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:.
XP_011 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM
. : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: :
XP_011 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK
.: . :. : :.. .... . .. : :.. .. .:. ::..::.: : ..
XP_011 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH
220 230 240 250 260
300 310 320 330 340 350
pF1KE1 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI
::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:.
XP_011 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE1 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTIL
::..::... ..... :.:. ::::.:.:::.:. ::.:::: :: : ::
XP_011 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ---
330 340 350 360 370
420 430 440 450 460 470
pF1KE1 KPLSECKSPSEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLL
..:. : ::. :.. . .: . . ..: :.:..: ...
XP_011 ------QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAE
380 390 400 410 420
480 490 500 510 520 530
pF1KE1 IRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTK
.:. ..:.:. ..: . .:: . . .:: ... . : . .: .. ... : .
XP_011 FRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLR
430 440 450 460 470 480
540 550 560
pF1KE1 VFFKIEEKEIEHALKDKALIGNILATGLP
: ... . .. .::::.
XP_011 VRLNVSQDDVLYALKDE
490 500
>>XP_016856878 (OMIM: 224690,601902) PREDICTED: origin r (615 aa)
initn: 404 init1: 167 opt: 516 Z-score: 519.8 bits: 106.2 E(85289): 3.2e-22
Smith-Waterman score: 603; 28.1% identity (62.3% similar) in 467 aa overlap (99-548:176-615)
70 80 90 100 110 120
pF1KE1 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
:.. . : :. .. . .. ::...:
XP_016 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
150 160 170 180 190 200
130 140 150 160 170
pF1KE1 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM
. :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:.
XP_016 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE1 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM
. : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: :
XP_016 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE1 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK
.: . :. : :.. .... . .. : :.. .. .:. ::..::.: : ..
XP_016 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE1 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI
::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:.
XP_016 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL
390 400 410 420 430 440
360 370 380 390 400 410
pF1KE1 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTIL
::..::... ..... :.:. ::::.:.:::.:. ::.:::: :: : ::
XP_016 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ---
450 460 470 480 490
420 430 440 450 460 470
pF1KE1 KPLSECKSPSEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLL
..:. : ::. :.. . .: . . ..: :.:..: ...
XP_016 ------QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAE
500 510 520 530
480 490 500 510 520 530
pF1KE1 IRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTK
.:. ..:.:. ..: . .:: . . .:: ... . : . .: .. ... : .
XP_016 FRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLR
540 550 560 570 580 590
540 550 560
pF1KE1 VFFKIEEKEIEHALKDKALIGNILATGLP
: ... . .. .::::.
XP_016 VRLNVSQDDVLYALKDE
600 610
>>NP_004144 (OMIM: 224690,601902) origin recognition com (861 aa)
initn: 353 init1: 167 opt: 516 Z-score: 517.6 bits: 106.2 E(85289): 4.3e-22
Smith-Waterman score: 603; 28.1% identity (62.3% similar) in 467 aa overlap (99-548:422-861)
70 80 90 100 110 120
pF1KE1 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
:.. . : :. .. . .. ::...:
NP_004 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
400 410 420 430 440 450
130 140 150 160 170
pF1KE1 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM
. :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:.
NP_004 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF
460 470 480 490 500 510
180 190 200 210 220 230
pF1KE1 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM
. : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: :
NP_004 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM
520 530 540 550 560 570
240 250 260 270 280 290
pF1KE1 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK
.: . :. : :.. .... . .. : :.. .. .:. ::..::.: : ..
NP_004 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH
580 590 600 610 620
300 310 320 330 340 350
pF1KE1 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI
::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:.
NP_004 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL
630 640 650 660 670 680
360 370 380 390 400 410
pF1KE1 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTIL
::..::... ..... :.:. ::::.:.:::.:. ::.:::: :: : ::
NP_004 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ---
690 700 710 720 730
420 430 440 450 460 470
pF1KE1 KPLSECKSPSEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLL
..:. : ::. :.. . .: . . ..: :.:..: ...
NP_004 ------QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAE
740 750 760 770 780
480 490 500 510 520 530
pF1KE1 IRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTK
.:. ..:.:. ..: . .:: . . .:: ... . : . .: .. ... : .
NP_004 FRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLR
790 800 810 820 830 840
540 550 560
pF1KE1 VFFKIEEKEIEHALKDKALIGNILATGLP
: ... . .. .::::.
NP_004 VRLNVSQDDVLYALKDE
850 860
>>NP_001177747 (OMIM: 224690,601902) origin recognition (861 aa)
initn: 353 init1: 167 opt: 516 Z-score: 517.6 bits: 106.2 E(85289): 4.3e-22
Smith-Waterman score: 603; 28.1% identity (62.3% similar) in 467 aa overlap (99-548:422-861)
70 80 90 100 110 120
pF1KE1 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
:.. . : :. .. . .. ::...:
NP_001 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
400 410 420 430 440 450
130 140 150 160 170
pF1KE1 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM
. :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:.
NP_001 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF
460 470 480 490 500 510
180 190 200 210 220 230
pF1KE1 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM
. : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: :
NP_001 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM
520 530 540 550 560 570
240 250 260 270 280 290
pF1KE1 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK
.: . :. : :.. .... . .. : :.. .. .:. ::..::.: : ..
NP_001 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH
580 590 600 610 620
300 310 320 330 340 350
pF1KE1 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI
::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:.
NP_001 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL
630 640 650 660 670 680
360 370 380 390 400 410
pF1KE1 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTIL
::..::... ..... :.:. ::::.:.:::.:. ::.:::: :: : ::
NP_001 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ---
690 700 710 720 730
420 430 440 450 460 470
pF1KE1 KPLSECKSPSEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLL
..:. : ::. :.. . .: . . ..: :.:..: ...
NP_001 ------QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAE
740 750 760 770 780
480 490 500 510 520 530
pF1KE1 IRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTK
.:. ..:.:. ..: . .:: . . .:: ... . : . .: .. ... : .
NP_001 FRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLR
790 800 810 820 830 840
540 550 560
pF1KE1 VFFKIEEKEIEHALKDKALIGNILATGLP
: ... . .. .::::.
NP_001 VRLNVSQDDVLYALKDE
850 860
>>XP_016856877 (OMIM: 224690,601902) PREDICTED: origin r (825 aa)
initn: 426 init1: 159 opt: 206 Z-score: 207.7 bits: 48.8 E(85289): 7.9e-05
Smith-Waterman score: 509; 28.0% identity (59.3% similar) in 460 aa overlap (99-548:422-825)
70 80 90 100 110 120
pF1KE1 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
:.. . : :. .. . .. ::...:
XP_016 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
400 410 420 430 440 450
130 140 150 160 170
pF1KE1 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM
. :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:.
XP_016 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF
460 470 480 490 500 510
180 190 200 210 220 230
pF1KE1 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTA
. : ::.. .. . .: .:.::.::::::: . .... :.. ..:
XP_016 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIR---------------CLQ-QAA
520 530 540 550
240 250 260 270 280 290
pF1KE1 QAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYT
:: : : ::. : :. : :. . : .: ..: : .. ::..:.
XP_016 QANDVPPFQYI---EVN---G---MKLTEPHQ------VYVQIL-QLDLLWTHKQDIMYN
560 570 580 590
300 310 320 330 340 350
pF1KE1 LFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQIVTILQDR
::.:: ....::...::::.:: .::. :...: . : ::: .:. ::..:
XP_016 LFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQLQQILRSR
600 610 620 630 640 650
360 370 380 390 400 410
pF1KE1 LNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECK
:... ..... :.:. ::::.:.:::.:. ::.:::: :: : :: .
XP_016 LKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ---------Q
660 670 680 690 700
420 430 440 450 460 470
pF1KE1 SPSEPLIPKRVGLIHISQVISEIDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIK
.:. : ::. :.. . .: . . ..: :.:..: ... .:. ..
XP_016 KPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAEFRRSGLE
710 720 730 740 750
480 490 500 510 520 530
pF1KE1 EVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEE
:.:. ..: . .:: . . .:: ... . : . .: .. ... : .: ... .
XP_016 EATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQ
760 770 780 790 800 810
540 550 560
pF1KE1 KEIEHALKDKALIGNILATGLP
.. .::::.
XP_016 DDVLYALKDE
820
560 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:39:50 2016 done: Sun Nov 6 22:39:51 2016
Total Scan time: 11.140 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]