FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1342, 187 aa
  1>>>pF1KE1342 187 - 187 aa - 187 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2255+/-0.000645; mu= 13.0419+/- 0.039
 mean_var=57.5999+/-11.509, 0's: 0 Z-trim(109.1): 10  B-trim: 0 in 0/51
 Lambda= 0.168991
 statistics sampled from 10643 (10648) to 10643 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.327), width:  16
 Scan time:  2.030

The best scores are:                                      opt bits E(32554)
CCDS47240.1 DHFR gene_id:1719|Hs108|chr5           ( 187) 1256 313.9 3.6e-86
CCDS2926.1 DHFR2 gene_id:200895|Hs108|chr3         ( 187) 1130 283.2 6.4e-77
CCDS78028.1 DHFR gene_id:1719|Hs108|chr5           ( 135)  904 228.0 1.9e-60
CCDS78029.1 DHFR gene_id:1719|Hs108|chr5           ( 129)  825 208.8 1.1e-54


>>CCDS47240.1 DHFR gene_id:1719|Hs108|chr5                (187 aa)
 initn: 1256 init1: 1256 opt: 1256  Z-score: 1660.4  bits: 313.9 E(32554): 3.6e-86
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)

               10        20        30        40        50        60
pF1KE1 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
              130       140       150       160       170       180

              
pF1KE1 EVYEKND
       :::::::
CCDS47 EVYEKND
              

>>CCDS2926.1 DHFR2 gene_id:200895|Hs108|chr3              (187 aa)
 initn: 1130 init1: 1130 opt: 1130  Z-score: 1494.4  bits: 283.2 E(32554): 6.4e-77
Smith-Waterman score: 1130; 93.4% identity (96.2% similar) in 183 aa overlap (5-187:5-187)

               10        20        30        40        50        60
pF1KE1 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
           :::::::::::::::::::: :::::::::::::::::::::::::::::.:::::
CCDS29 MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
       ::::::::: ::::::::::::::::::::.:::::::::::.:::::::::.:::::::
CCDS29 IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
       :::::::: :::::::::::::::::::: :::::::::::::::::::::: : :::::
CCDS29 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
              130       140       150       160       170       180

              
pF1KE1 EVYEKND
       :: ::.:
CCDS29 EVCEKDD
              

>>CCDS78028.1 DHFR gene_id:1719|Hs108|chr5                (135 aa)
 initn: 904 init1: 904 opt: 904  Z-score: 1198.9  bits: 228.0 E(32554): 1.9e-60
Smith-Waterman score: 904; 100.0% identity (100.0% similar) in 135 aa overlap (53-187:1-135)

             30        40        50        60        70        80  
pF1KE1 LPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKE
                                     ::::::::::::::::::::::::::::::
CCDS78                               MGKKTWFSIPEKNRPLKGRINLVLSRELKE
                                             10        20        30

             90       100       110       120       130       140  
pF1KE1 PPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQD
               40        50        60        70        80        90

            150       160       170       180       
pF1KE1 FESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
       :::::::::::::::::::::::::::::::::::::::::::::
CCDS78 FESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
              100       110       120       130     

>>CCDS78029.1 DHFR gene_id:1719|Hs108|chr5                (129 aa)
 initn: 825 init1: 825 opt: 825  Z-score: 1095.1  bits: 208.8 E(32554): 1.1e-54
Smith-Waterman score: 825; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123)

               10        20        30        40        50        60
pF1KE1 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
       :::                                                         
CCDS78 VYKIPRCSL                                                   
                                                                   




187 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 03:08:32 2016 done: Mon Nov  7 03:08:33 2016
 Total Scan time:  2.030 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]