Result of FASTA (omim) for
pFN21AE1340
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1340, 802 aa
1>>>pF1KE1340 802 - 802 aa - 802 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.0682+/-0.000577; mu= -22.7470+/- 0.035
mean_var=889.3169+/-199.744, 0's: 0 Z-trim(118.8): 715 B-trim: 0 in 0/60
Lambda= 0.043008
statistics sampled from 31258 (32046) to 31258 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.376), width: 16
Scan time: 14.560
The best scores are: opt bits E(85289)
NP_998812 (OMIM: 134935) fibroblast growth factor ( 802) 5442 354.8 8.7e-97
XP_005265895 (OMIM: 134935) PREDICTED: fibroblast ( 802) 5442 354.8 8.7e-97
NP_002002 (OMIM: 134935) fibroblast growth factor ( 802) 5442 354.8 8.7e-97
XP_011532766 (OMIM: 134935) PREDICTED: fibroblast ( 833) 5442 354.8 8.9e-97
XP_011532767 (OMIM: 134935) PREDICTED: fibroblast ( 696) 4722 310.0 2.3e-83
NP_000133 (OMIM: 100800,109800,114500,134934,14600 ( 806) 3134 211.6 1.1e-53
XP_006713936 (OMIM: 100800,109800,114500,134934,14 ( 807) 3132 211.4 1.2e-53
XP_006713935 (OMIM: 100800,109800,114500,134934,14 ( 807) 3122 210.8 1.9e-53
XP_011511724 (OMIM: 100800,109800,114500,134934,14 ( 808) 3120 210.7 2.1e-53
XP_011511722 (OMIM: 100800,109800,114500,134934,14 ( 809) 3118 210.6 2.2e-53
NP_001307587 (OMIM: 101200,101400,101600,123150,12 ( 819) 3055 206.7 3.4e-52
NP_000132 (OMIM: 101200,101400,101600,123150,12350 ( 821) 3035 205.4 8.1e-52
NP_001156685 (OMIM: 100800,109800,114500,134934,14 ( 808) 3022 204.6 1.4e-51
XP_006713934 (OMIM: 100800,109800,114500,134934,14 ( 809) 3020 204.5 1.5e-51
XP_016868713 (OMIM: 101600,123150,136350,147950,16 ( 818) 3018 204.4 1.7e-51
XP_016868714 (OMIM: 101600,123150,136350,147950,16 ( 818) 3018 204.4 1.7e-51
XP_016868709 (OMIM: 101600,123150,136350,147950,16 ( 851) 3018 204.4 1.7e-51
XP_016871412 (OMIM: 101200,101400,101600,123150,12 ( 749) 3016 204.2 1.7e-51
XP_006713933 (OMIM: 100800,109800,114500,134934,14 ( 810) 3008 203.8 2.6e-51
XP_006713932 (OMIM: 100800,109800,114500,134934,14 ( 810) 3008 203.8 2.6e-51
XP_006713931 (OMIM: 100800,109800,114500,134934,14 ( 811) 3006 203.6 2.8e-51
NP_075418 (OMIM: 101200,101400,101600,123150,12350 ( 732) 3002 203.3 3.1e-51
XP_006717771 (OMIM: 101200,101400,101600,123150,12 ( 839) 2997 203.1 4.2e-51
XP_016871410 (OMIM: 101200,101400,101600,123150,12 ( 804) 2983 202.2 7.4e-51
XP_016868717 (OMIM: 101600,123150,136350,147950,16 ( 729) 2961 200.8 1.8e-50
XP_016868716 (OMIM: 101600,123150,136350,147950,16 ( 762) 2961 200.8 1.9e-50
XP_016868715 (OMIM: 101600,123150,136350,147950,16 ( 764) 2959 200.7 2e-50
XP_016871411 (OMIM: 101200,101400,101600,123150,12 ( 750) 2958 200.6 2.1e-50
NP_001138390 (OMIM: 101200,101400,101600,123150,12 ( 704) 2954 200.3 2.4e-50
NP_075594 (OMIM: 101600,123150,136350,147950,16625 ( 731) 2950 200.1 2.9e-50
XP_011542752 (OMIM: 101600,123150,136350,147950,16 ( 764) 2950 200.1 3e-50
NP_001167535 (OMIM: 101600,123150,136350,147950,16 ( 812) 2949 200.1 3.2e-50
NP_001167534 (OMIM: 101600,123150,136350,147950,16 ( 820) 2949 200.1 3.2e-50
XP_011542749 (OMIM: 101600,123150,136350,147950,16 ( 853) 2949 200.1 3.3e-50
XP_006717774 (OMIM: 101200,101400,101600,123150,12 ( 752) 2944 199.7 3.8e-50
NP_001138388 (OMIM: 101200,101400,101600,123150,12 ( 706) 2940 199.5 4.4e-50
XP_016871413 (OMIM: 101200,101400,101600,123150,12 ( 725) 2940 199.5 4.4e-50
NP_001167537 (OMIM: 101600,123150,136350,147950,16 ( 733) 2939 199.4 4.7e-50
NP_075593 (OMIM: 101600,123150,136350,147950,16625 ( 733) 2939 199.4 4.7e-50
NP_001167536 (OMIM: 101600,123150,136350,147950,16 ( 820) 2940 199.5 4.8e-50
NP_056934 (OMIM: 101600,123150,136350,147950,16625 ( 820) 2940 199.5 4.8e-50
NP_001167538 (OMIM: 101600,123150,136350,147950,16 ( 853) 2940 199.6 4.9e-50
NP_075598 (OMIM: 101600,123150,136350,147950,16625 ( 822) 2929 198.9 7.7e-50
XP_011542748 (OMIM: 101600,123150,136350,147950,16 ( 855) 2929 198.9 7.9e-50
XP_016871409 (OMIM: 101200,101400,101600,123150,12 ( 805) 2925 198.6 9e-50
NP_075259 (OMIM: 101200,101400,101600,123150,12350 ( 822) 2916 198.1 1.3e-49
XP_016868712 (OMIM: 101600,123150,136350,147950,16 ( 828) 2890 196.4 4.1e-49
XP_016868708 (OMIM: 101600,123150,136350,147950,16 ( 861) 2890 196.5 4.2e-49
XP_006717775 (OMIM: 101200,101400,101600,123150,12 ( 726) 2886 196.1 4.5e-49
XP_016871414 (OMIM: 101200,101400,101600,123150,12 ( 689) 2882 195.8 5.2e-49
>>NP_998812 (OMIM: 134935) fibroblast growth factor rece (802 aa)
initn: 5442 init1: 5442 opt: 5442 Z-score: 1858.6 bits: 354.8 E(85289): 8.7e-97
Smith-Waterman score: 5442; 100.0% identity (100.0% similar) in 802 aa overlap (1-802:1-802)
10 20 30 40 50 60
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
730 740 750 760 770 780
790 800
pF1KE1 VFSHDPLPLGSSSFPFGSGVQT
::::::::::::::::::::::
NP_998 VFSHDPLPLGSSSFPFGSGVQT
790 800
>>XP_005265895 (OMIM: 134935) PREDICTED: fibroblast grow (802 aa)
initn: 5442 init1: 5442 opt: 5442 Z-score: 1858.6 bits: 354.8 E(85289): 8.7e-97
Smith-Waterman score: 5442; 100.0% identity (100.0% similar) in 802 aa overlap (1-802:1-802)
10 20 30 40 50 60
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
730 740 750 760 770 780
790 800
pF1KE1 VFSHDPLPLGSSSFPFGSGVQT
::::::::::::::::::::::
XP_005 VFSHDPLPLGSSSFPFGSGVQT
790 800
>>NP_002002 (OMIM: 134935) fibroblast growth factor rece (802 aa)
initn: 5442 init1: 5442 opt: 5442 Z-score: 1858.6 bits: 354.8 E(85289): 8.7e-97
Smith-Waterman score: 5442; 100.0% identity (100.0% similar) in 802 aa overlap (1-802:1-802)
10 20 30 40 50 60
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
730 740 750 760 770 780
790 800
pF1KE1 VFSHDPLPLGSSSFPFGSGVQT
::::::::::::::::::::::
NP_002 VFSHDPLPLGSSSFPFGSGVQT
790 800
>>XP_011532766 (OMIM: 134935) PREDICTED: fibroblast grow (833 aa)
initn: 5442 init1: 5442 opt: 5442 Z-score: 1858.4 bits: 354.8 E(85289): 8.9e-97
Smith-Waterman score: 5442; 100.0% identity (100.0% similar) in 802 aa overlap (1-802:32-833)
10 20 30
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVEL
::::::::::::::::::::::::::::::
XP_011 DWKWSGSDQGGGGRQLVGSPAWVPESCEKEMRLLLALLGVLLSVPGPPVLSLEASEEVEL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 EPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIAS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 FLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWT
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 HPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 MESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 CKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 YTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE1 RGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLV
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE1 SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNAS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE1 DKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE1 DLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIAD
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE1 FGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPY
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE1 PGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV
730 740 750 760 770 780
760 770 780 790 800
pF1KE1 SEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
790 800 810 820 830
>>XP_011532767 (OMIM: 134935) PREDICTED: fibroblast grow (696 aa)
initn: 4722 init1: 4722 opt: 4722 Z-score: 1617.8 bits: 310.0 E(85289): 2.3e-83
Smith-Waterman score: 4722; 100.0% identity (100.0% similar) in 696 aa overlap (107-802:1-696)
80 90 100 110 120 130
pF1KE1 GRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDP
::::::::::::::::::::::::::::::
XP_011 MIVLQNLTLITGDSLTSSNDDEDPKSHRDP
10 20 30
140 150 160 170 180 190
pF1KE1 SNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENR
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 IGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLP
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 ANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 VLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 SLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGV
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 RLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQ
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 ASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKG
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE1 NLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAAR
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE1 NVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFG
520 530 540 550 560 570
680 690 700 710 720 730
pF1KE1 ILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTF
580 590 600 610 620 630
740 750 760 770 780 790
pF1KE1 KQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPF
640 650 660 670 680 690
800
pF1KE1 GSGVQT
::::::
XP_011 GSGVQT
>>NP_000133 (OMIM: 100800,109800,114500,134934,146000,14 (806 aa)
initn: 2737 init1: 1760 opt: 3134 Z-score: 1084.6 bits: 211.6 E(85289): 1.1e-53
Smith-Waterman score: 3134; 63.0% identity (79.0% similar) in 795 aa overlap (5-788:8-795)
10 20 30 40 50
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLE--QQEQELTVALGQPVRL
::: .. : : :: . ..: . .:. : :::: :. . :. :.:
NP_000 MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQ-LVFGSGDAVEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CC---GRAERGGH-WYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQ
: : . : : :.:. :.:. :: ::.. . ::.: : : : .. ::
NP_000 SCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 NLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFR
.... . :. ::.:::: . : .. . :::::.:.::.::: ::::.:::.::
NP_000 HFSVRVTDA-PSSGDDEDGE---DEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVG
:::::::::.: :::.:. :.::.:::::.::::.::::::::::::::.:::.::: :
NP_000 CPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 SIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVING
::: .: :::::::::::::::::::: :::.:::::. ::::::::::::::::. .::
NP_000 SIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNG
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 SSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLT
:. : :: ::: ::::: :.. :.::: :.::. :::::::::::::::.:..::::.
NP_000 SKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 VLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKL
::: :. : . :. :. :. : . . ... . : : .. . : ::.:.
NP_000 VLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSP-TVHKI
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 SRFPLARQFSLESGSSGKSSSSLVRGVRLSSS-GPALLAGLVSLDLPLDPLWEFPRDRLV
::::: :: ::::..: .:.. ::: .::::. ::.: :.. :.:: :: ::. : ::.
NP_000 SRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTL-ANVSELELPADPKWELSRARLT
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 LGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIG
:::::::::::::: :::.:.: : . :::::::::.:.::::.:::::::.::.::
NP_000 LGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIG
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE1 RHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPV
.:::::::::.::: :::::.:: ::::::::::::::::: : : : . : :.:
NP_000 KHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKD
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE1 LVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSN
::::::::::::.:: :.::::::::::::::::::::::::::::: ::..::::::.:
NP_000 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTN
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE1 GRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRM
::::::::::::::::::::::::::::.::::::::::::::::::::::.::.:::::
NP_000 GRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRM
660 670 680 690 700 710
710 720 730 740 750 760
pF1KE1 DRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS-EEYLDLRLTFGPYSPS
:.: .: .:: .:::::::::::::::::::: ::.:: ..: .::::: : :::.
NP_000 DKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPG
720 730 740 750 760 770
770 780 790 800
pF1KE1 GGDA-SSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
: :. ::. :..::::.:: ::
NP_000 GQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
780 790 800
>>XP_006713936 (OMIM: 100800,109800,114500,134934,146000 (807 aa)
initn: 2692 init1: 1773 opt: 3132 Z-score: 1083.9 bits: 211.4 E(85289): 1.2e-53
Smith-Waterman score: 3132; 62.9% identity (78.9% similar) in 796 aa overlap (5-788:8-796)
10 20 30 40 50
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLE--QQEQELTVALGQPVRL
::: .. : : :: . ..: . .:. : :::: :. . :. :.:
XP_006 MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQ-LVFGSGDAVEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CC---GRAERGGH-WYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQ
: : . : : :.:. :.:. :: ::.. . ::.: : : : .. ::
XP_006 SCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 NLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFR
.... . :. ::.:::: . : .. . :::::.:.::.::: ::::.:::.::
XP_006 HFSVRVTDA-PSSGDDEDGE---DEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVG
:::::::::.: :::.:. :.::.:::::.::::.::::::::::::::.:::.::: :
XP_006 CPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 SIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVING
::: .: :::::::::::::::::::: :::.:::::. ::::::::::::::::. .::
XP_006 SIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNG
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 SSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLT
:. : :: ::: ::::: :.. :.::: :.::. :::::::::::::::.:..::::.
XP_006 SKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 VLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKL
::: :. : . :. :. :. : . . ... . : : .. . : ::.:.
XP_006 VLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSP-TVHKI
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 SRFPLARQFSLESGSSGKSSSSLVRGVRLSSS-GPALLAGLVSLDLPLDPLWEFPRDRLV
::::: :: ::::..: .:.. ::: .::::. ::.: :.. :.:: :: ::. : ::.
XP_006 SRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTL-ANVSELELPADPKWELSRARLT
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 LGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIG
:::::::::::::: :::.:.: : . :::::::::.:.::::.:::::::.::.::
XP_006 LGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIG
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE1 RHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPV
.:::::::::.::: :::::.:: ::::::::::::::::: : : : . : :.:
XP_006 KHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKD
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE1 LVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSN
::::::::::::.:: :.::::::::::::::::::::::::::::: ::..::::::.:
XP_006 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTN
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE1 GRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRM
::::::::::::::::::::::::::::.::::::::::::::::::::::.::.:::::
XP_006 GRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRM
660 670 680 690 700 710
710 720 730 740 750 760
pF1KE1 DRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS--EEYLDLRLTFGPYSP
:.: .: .:: .:::::::::::::::::::: ::.:: ..: .::::: : :::
XP_006 DKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDQEYLDLSAPFEQYSP
720 730 740 750 760 770
770 780 790 800
pF1KE1 SGGDA-SSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
.: :. ::. :..::::.:: ::
XP_006 GGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
780 790 800
>>XP_006713935 (OMIM: 100800,109800,114500,134934,146000 (807 aa)
initn: 1955 init1: 1897 opt: 3122 Z-score: 1080.6 bits: 210.8 E(85289): 1.9e-53
Smith-Waterman score: 3122; 62.9% identity (78.9% similar) in 796 aa overlap (5-788:8-796)
10 20 30 40 50
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLE--QQEQELTVALGQPVRL
::: .. : : :: . ..: . .:. : :::: :. . :. :.:
XP_006 MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQ-LVFGSGDAVEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CC---GRAERGGH-WYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQ
: : . : : :.:. :.:. :: ::.. . ::.: : : : .. ::
XP_006 SCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 NLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFR
.... . :. ::.:::: . : .. . :::::.:.::.::: ::::.:::.::
XP_006 HFSVRVTDA-PSSGDDEDGE---DEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVG
:::::::::.: :::.:. :.::.:::::.::::.::::::::::::::.:::.::: :
XP_006 CPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 SIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVING
::: .: :::::::::::::::::::: :::.:::::. ::::::::::::::::. .::
XP_006 SIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNG
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 SSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLT
:. : :: ::: ::::: :.. :.::: :.::. :::::::::::::::.:..::::.
XP_006 SKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 VLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKL
::: :. : . :. :. :. : . . ... . : : .. . : ::.:.
XP_006 VLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSP-TVHKI
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 SRFPLARQ-FSLESGSSGKSSSSLVRGVRLSSS-GPALLAGLVSLDLPLDPLWEFPRDRL
::::: :: ::::..: .:.. ::: .::::. ::.: :.. :.:: :: ::. : ::
XP_006 SRFPLKRQQVSLESNASMSSNTPLVRIARLSSGEGPTL-ANVSELELPADPKWELSRARL
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 VLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLI
.:::::::::::::: :::.:.: : . :::::::::.:.::::.:::::::.::.:
XP_006 TLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMI
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE1 GRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFP
:.:::::::::.::: :::::.:: ::::::::::::::::: : : : . : :.:
XP_006 GKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFK
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE1 VLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTS
::::::::::::.:: :.::::::::::::::::::::::::::::: ::..::::::.
XP_006 DLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTT
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE1 NGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHR
:::::::::::::::::::::::::::::.::::::::::::::::::::::.::.::::
XP_006 NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHR
660 670 680 690 700 710
710 720 730 740 750 760
pF1KE1 MDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS-EEYLDLRLTFGPYSP
::.: .: .:: .:::::::::::::::::::: ::.:: ..: .::::: : :::
XP_006 MDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSP
720 730 740 750 760 770
770 780 790 800
pF1KE1 SGGDA-SSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
.: :. ::. :..::::.:: ::
XP_006 GGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
780 790 800
>>XP_011511724 (OMIM: 100800,109800,114500,134934,146000 (808 aa)
initn: 1910 init1: 1910 opt: 3120 Z-score: 1079.9 bits: 210.7 E(85289): 2.1e-53
Smith-Waterman score: 3120; 62.9% identity (78.8% similar) in 797 aa overlap (5-788:8-797)
10 20 30 40 50
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLE--QQEQELTVALGQPVRL
::: .. : : :: . ..: . .:. : :::: :. . :. :.:
XP_011 MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQ-LVFGSGDAVEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CC---GRAERGGH-WYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQ
: : . : : :.:. :.:. :: ::.. . ::.: : : : .. ::
XP_011 SCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 NLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFR
.... . :. ::.:::: . : .. . :::::.:.::.::: ::::.:::.::
XP_011 HFSVRVTDA-PSSGDDEDGE---DEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVG
:::::::::.: :::.:. :.::.:::::.::::.::::::::::::::.:::.::: :
XP_011 CPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 SIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVING
::: .: :::::::::::::::::::: :::.:::::. ::::::::::::::::. .::
XP_011 SIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNG
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 SSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLT
:. : :: ::: ::::: :.. :.::: :.::. :::::::::::::::.:..::::.
XP_011 SKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 VLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKL
::: :. : . :. :. :. : . . ... . : : .. . : ::.:.
XP_011 VLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSP-TVHKI
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 SRFPLARQ-FSLESGSSGKSSSSLVRGVRLSSS-GPALLAGLVSLDLPLDPLWEFPRDRL
::::: :: ::::..: .:.. ::: .::::. ::.: :.. :.:: :: ::. : ::
XP_011 SRFPLKRQQVSLESNASMSSNTPLVRIARLSSGEGPTL-ANVSELELPADPKWELSRARL
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 VLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLI
.:::::::::::::: :::.:.: : . :::::::::.:.::::.:::::::.::.:
XP_011 TLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMI
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE1 GRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFP
:.:::::::::.::: :::::.:: ::::::::::::::::: : : : . : :.:
XP_011 GKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFK
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE1 VLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTS
::::::::::::.:: :.::::::::::::::::::::::::::::: ::..::::::.
XP_011 DLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTT
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE1 NGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHR
:::::::::::::::::::::::::::::.::::::::::::::::::::::.::.::::
XP_011 NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHR
660 670 680 690 700 710
710 720 730 740 750 760
pF1KE1 MDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS--EEYLDLRLTFGPYS
::.: .: .:: .:::::::::::::::::::: ::.:: ..: .::::: : ::
XP_011 MDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDQEYLDLSAPFEQYS
720 730 740 750 760 770
770 780 790 800
pF1KE1 PSGGDA-SSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
:.: :. ::. :..::::.:: ::
XP_011 PGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
780 790 800
>>XP_011511722 (OMIM: 100800,109800,114500,134934,146000 (809 aa)
initn: 2626 init1: 1707 opt: 3118 Z-score: 1079.2 bits: 210.6 E(85289): 2.2e-53
Smith-Waterman score: 3118; 62.8% identity (78.7% similar) in 798 aa overlap (5-788:8-798)
10 20 30 40 50
pF1KE1 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLE--QQEQELTVALGQPVRL
::: .. : : :: . ..: . .:. : :::: :. . :. :.:
XP_011 MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQ-LVFGSGDAVEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CC---GRAERGGH-WYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQ
: : . : : :.:. :.:. :: ::.. . ::.: : : : .. ::
XP_011 SCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 NLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFR
.... . :. ::.:::: . : .. . :::::.:.::.::: ::::.:::.::
XP_011 HFSVRVTDA-PSSGDDEDGE---DEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVG
:::::::::.: :::.:. :.::.:::::.::::.::::::::::::::.:::.::: :
XP_011 CPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 SIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVING
::: .: :::::::::::::::::::: :::.:::::. ::::::::::::::::. .::
XP_011 SIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNG
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 SSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLT
:. : :: ::: ::::: :.. :.::: :.::. :::::::::::::::.:..::::.
XP_011 SKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 VLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKL
::: :. : . :. :. :. : . . ... . : : .. . : ::.:.
XP_011 VLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSP-TVHKI
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 SRFPLARQF--SLESGSSGKSSSSLVRGVRLSSS-GPALLAGLVSLDLPLDPLWEFPRDR
::::: :: ::::..: .:.. ::: .::::. ::.: :.. :.:: :: ::. : :
XP_011 SRFPLKRQVTVSLESNASMSSNTPLVRIARLSSGEGPTL-ANVSELELPADPKWELSRAR
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 LVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKL
:.:::::::::::::: :::.:.: : . :::::::::.:.::::.:::::::.::.
XP_011 LTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKM
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE1 IGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSF
::.:::::::::.::: :::::.:: ::::::::::::::::: : : : . : :.:
XP_011 IGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTF
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE1 PVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKT
::::::::::::.:: :.::::::::::::::::::::::::::::: ::..::::::
XP_011 KDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKT
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE1 SNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGH
.:::::::::::::::::::::::::::::.::::::::::::::::::::::.::.:::
XP_011 TNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGH
660 670 680 690 700 710
710 720 730 740 750 760
pF1KE1 RMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS--EEYLDLRLTFGPY
:::.: .: .:: .:::::::::::::::::::: ::.:: ..: .::::: : :
XP_011 RMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDQEYLDLSAPFEQY
720 730 740 750 760 770
770 780 790 800
pF1KE1 SPSGGDA-SSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT
::.: :. ::. :..::::.:: ::
XP_011 SPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT
780 790 800
802 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:04:22 2016 done: Sun Nov 6 23:04:24 2016
Total Scan time: 14.560 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]