Result of FASTA (omim) for
pFN21AE1339
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1339, 520 aa
1>>>pF1KE1339 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4976+/-0.000492; mu= -0.8187+/- 0.031
mean_var=489.7052+/-100.228, 0's: 0 Z-trim(121.3): 558 B-trim: 42 in 1/60
Lambda= 0.057957
statistics sampled from 37151 (37729) to 37151 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.442), width: 16
Scan time: 11.780
The best scores are: opt bits E(85289)
XP_011510384 (OMIM: 604870) PREDICTED: macrophage ( 520) 3627 317.9 4.6e-86
NP_006761 (OMIM: 604870) macrophage receptor MARCO ( 520) 3627 317.9 4.6e-86
XP_011510385 (OMIM: 604870) PREDICTED: macrophage ( 399) 2645 235.6 2.1e-61
XP_016860660 (OMIM: 604870) PREDICTED: macrophage ( 322) 1774 162.7 1.5e-39
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 944 94.2 3e-18
XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 907 91.2 2.8e-17
NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 907 91.2 2.8e-17
NP_001281276 (OMIM: 120252,136800,609140) collagen ( 638) 889 89.1 4.3e-17
NP_005193 (OMIM: 120252,136800,609140) collagen al ( 703) 889 89.1 4.6e-17
XP_005270534 (OMIM: 120252,136800,609140) PREDICTE ( 780) 889 89.2 4.9e-17
XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 889 89.4 6.2e-17
XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 886 89.3 8.3e-17
XP_011539019 (OMIM: 120260,600204,603932,614284) P ( 508) 875 87.8 8.5e-17
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 886 89.3 8.5e-17
NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 886 89.3 8.6e-17
XP_011517442 (OMIM: 608461,615155) PREDICTED: coll (1842) 888 89.6 8.7e-17
XP_016855822 (OMIM: 120260,600204,603932,614284) P ( 595) 875 87.9 9.3e-17
XP_011539017 (OMIM: 120260,600204,603932,614284) P ( 599) 875 87.9 9.4e-17
XP_011539018 (OMIM: 120260,600204,603932,614284) P ( 599) 875 87.9 9.4e-17
XP_006710428 (OMIM: 120260,600204,603932,614284) P ( 689) 875 88.0 1e-16
NP_001843 (OMIM: 120260,600204,603932,614284) coll ( 689) 875 88.0 1e-16
XP_016855821 (OMIM: 120260,600204,603932,614284) P ( 693) 875 88.0 1e-16
XP_016855826 (OMIM: 120280,154780,228520,603932,60 (1323) 876 88.4 1.4e-16
NP_511040 (OMIM: 120210,614134,614135) collagen al ( 678) 868 87.4 1.5e-16
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 877 88.6 1.6e-16
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 877 88.7 1.6e-16
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 877 88.7 1.6e-16
NP_542197 (OMIM: 120280,154780,228520,603932,60484 (1690) 876 88.5 1.7e-16
NP_001177638 (OMIM: 120280,154780,228520,603932,60 (1767) 876 88.6 1.7e-16
NP_001845 (OMIM: 120280,154780,228520,603932,60484 (1806) 876 88.6 1.7e-16
NP_542196 (OMIM: 120280,154780,228520,603932,60484 (1818) 876 88.6 1.7e-16
XP_016855824 (OMIM: 120280,154780,228520,603932,60 (1855) 876 88.6 1.8e-16
XP_016855823 (OMIM: 120280,154780,228520,603932,60 (1857) 876 88.6 1.8e-16
XP_011517447 (OMIM: 608461,615155) PREDICTED: coll (1049) 870 87.8 1.8e-16
XP_006717373 (OMIM: 608461,615155) PREDICTED: coll (1087) 870 87.8 1.8e-16
NP_001842 (OMIM: 120210,614134,614135) collagen al ( 921) 868 87.5 1.8e-16
XP_016870728 (OMIM: 608461,615155) PREDICTED: coll (1214) 870 87.9 1.9e-16
XP_011517446 (OMIM: 608461,615155) PREDICTED: coll (1352) 870 87.9 2.1e-16
XP_011517445 (OMIM: 608461,615155) PREDICTED: coll (1353) 870 87.9 2.1e-16
XP_011517444 (OMIM: 608461,615155) PREDICTED: coll (1401) 870 87.9 2.1e-16
XP_006717371 (OMIM: 608461,615155) PREDICTED: coll (1842) 870 88.1 2.5e-16
XP_011517440 (OMIM: 608461,615155) PREDICTED: coll (1858) 870 88.1 2.5e-16
NP_116277 (OMIM: 608461,615155) collagen alpha-1(X (1860) 870 88.1 2.5e-16
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 865 87.5 2.8e-16
NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 865 87.5 2.9e-16
XP_016882338 (OMIM: 120216) PREDICTED: collagen al ( 966) 859 86.8 3.2e-16
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 861 87.1 3.4e-16
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 861 87.2 3.6e-16
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 861 87.2 3.6e-16
NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 861 87.2 3.7e-16
>>XP_011510384 (OMIM: 604870) PREDICTED: macrophage rece (520 aa)
initn: 3627 init1: 3627 opt: 3627 Z-score: 1666.1 bits: 317.9 E(85289): 4.6e-86
Smith-Waterman score: 3627; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE1 MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQ
430 440 450 460 470 480
490 500 510 520
pF1KE1 IWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
::::::::::::::::::::::::::::::::::::::::
XP_011 IWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
490 500 510 520
>>NP_006761 (OMIM: 604870) macrophage receptor MARCO [Ho (520 aa)
initn: 3627 init1: 3627 opt: 3627 Z-score: 1666.1 bits: 317.9 E(85289): 4.6e-86
Smith-Waterman score: 3627; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE1 MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQ
430 440 450 460 470 480
490 500 510 520
pF1KE1 IWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
::::::::::::::::::::::::::::::::::::::::
NP_006 IWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
490 500 510 520
>>XP_011510385 (OMIM: 604870) PREDICTED: macrophage rece (399 aa)
initn: 2645 init1: 2645 opt: 2645 Z-score: 1223.6 bits: 235.6 E(85289): 2.1e-61
Smith-Waterman score: 2645; 100.0% identity (100.0% similar) in 367 aa overlap (154-520:33-399)
130 140 150 160 170 180
pF1KE1 RVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAM
::::::::::::::::::::::::::::::
XP_011 NKKILKEDELLSETQQAAFHQIAMEPFEINGLQGHKGAMGMPGAPGPPGPPAEKGAKGAM
10 20 30 40 50 60
190 200 210 220 230 240
pF1KE1 GRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGET
70 80 90 100 110 120
250 260 270 280 290 300
pF1KE1 GTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQP
130 140 150 160 170 180
310 320 330 340 350 360
pF1KE1 GLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRK
190 200 210 220 230 240
370 380 390 400 410 420
pF1KE1 GESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVS
250 260 270 280 290 300
430 440 450 460 470 480
pF1KE1 VRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWL
310 320 330 340 350 360
490 500 510 520
pF1KE1 DNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
:::::::::::::::::::::::::::::::::::::
XP_011 DNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
370 380 390
>>XP_016860660 (OMIM: 604870) PREDICTED: macrophage rece (322 aa)
initn: 1758 init1: 1758 opt: 1774 Z-score: 831.0 bits: 162.7 E(85289): 1.5e-39
Smith-Waterman score: 1774; 90.0% identity (93.0% similar) in 301 aa overlap (1-298:1-300)
10 20 30 40 50 60
pF1KE1 MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPK
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 GETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGA-QGSKGDF--GRPGPPGLAGFPGAK
:::::::::::::::::.::. .: : .: : :.:: .: :: . : ..
XP_016 GETGTKGEKGDLGLPGSQGDE-ESGPALGLGKQGRLTGGKGKGIDSRRETPGSQNPPLTE
250 260 270 280 290
300 310 320 330 340 350
pF1KE1 GDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQ
:
XP_016 GAISRTVFLKPRANIIRAVWVLA
300 310 320
>>NP_000081 (OMIM: 120180,130020,130050) collagen alpha- (1466 aa)
initn: 2388 init1: 859 opt: 944 Z-score: 448.7 bits: 94.2 E(85289): 3e-18
Smith-Waterman score: 959; 50.3% identity (64.7% similar) in 286 aa overlap (148-418:717-993)
120 130 140 150 160 170
pF1KE1 AQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQG---HKGAMGMPGAPGPPGPP
: :.::::: ..:..: :: : : :
NP_000 GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP
690 700 710 720 730 740
180 190 200 210 220
pF1KE1 AEKGAKGAMGRDGATGPSGPQGPPGV------KGEAG------LQGPQGAPGKQGATGTP
. :: :. :.:: ::.:: :::: :::.: . ::.:.::..: :: :
NP_000 GGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPP
750 760 770 780 790 800
230 240 250 260 270 280
pF1KE1 GPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDF
:: : :. :..: : ::: :. ::::. : :: : : .: :: ::: :: ::.
NP_000 GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG---PPGPQGVKGER
810 820 830 840 850 860
290 300 310 320 330 340
pF1KE1 GRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSP
: :: :: ::::::.: : :: .: ::::: : :: : :: ::. : .::::
NP_000 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG------APGSP
870 880 890 900 910
350 360 370 380 390 400
pF1KE1 GATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVK
:..: ::. :. : .:. : .: :.::: :. : :. ::::: : :: :. : ::::
NP_000 GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK
920 930 940 950 960 970
410 420 430 440 450 460
pF1KE1 GSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRM
: ::. :..: .::::
NP_000 GESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN
980 990 1000 1010 1020 1030
>--
initn: 812 init1: 812 opt: 865 Z-score: 413.0 bits: 87.5 E(85289): 2.9e-16
Smith-Waterman score: 894; 46.1% identity (62.2% similar) in 304 aa overlap (136-418:150-453)
110 120 130 140 150 160
pF1KE1 LAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMP
:.. . . .:. .. :: :. : : :
NP_000 NGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPP
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 GAPGPPG----P--PAEKGAKGAMGRDGATGPSGPQGPPGV---KGEAGLQGPQGAPGKQ
: ::::: : :. : .: :. : .::::: ::::. .: :: .: .: ::.
NP_000 GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 GATGTPGPQGEKGSKGDGGLIGPKGETG---TKGEKGDLGLPGSKGDRGMKGDAGVMGPP
: : ::: : :: : :. : ::. : .::::. : :: ::. :. :. :. ::
NP_000 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 GAQGSKGDFGRPGPPGLAGF---PGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSP
: .:. :. :::: :: :: ::.:..:::: : :: : : :::::: : ::::
NP_000 GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP
300 310 320 330 340 350
340 350 360 370 380
pF1KE1 GRAGLPGS---PGSPGATGLKGSKGDTGLQGQQGRKGE---SGVPGPAGVKGEQGSPGLA
: : ::. :: : .: .: : :..:. : ::: .:.:: :. : .: :: :
NP_000 GSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE1 GPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWG
: .:::: : :. : .:..:: : .::.:: :
NP_000 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE1 TICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWG
NP_000 GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP
480 490 500 510 520 530
>--
initn: 1441 init1: 740 opt: 758 Z-score: 364.7 bits: 78.6 E(85289): 1.4e-13
Smith-Waterman score: 758; 46.7% identity (61.1% similar) in 244 aa overlap (142-382:477-714)
120 130 140 150 160 170
pF1KE1 RLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPP
:. ::.::::..: : :.:: ::
NP_000 GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPA
450 460 470 480 490 500
180 190 200 210 220 230
pF1KE1 GPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSK
: :.:: : : ::.: : .: :: : :. : :.::..: : :: :::.:
NP_000 G---ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP
510 520 530 540 550 560
240 250 260 270 280
pF1KE1 GDGGLIGPKGETGT---KGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPP
: : ::.:. :. : ::. : ::..:.:: : : .::: :..:. : :::
NP_000 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP---GKNGETGPQGPP
570 580 590 600 610 620
290 300 310 320 330 340
pF1KE1 GLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLK
: .: : ::: : :: ::. : ::. : :: .:.:: : : :: ::.::. : .:
NP_000 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP
630 640 650 660 670 680
350 360 370 380 390 400
pF1KE1 GSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQ
: .: :: : : .: .: ::: : :: : ::
NP_000 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK
690 700 710 720 730 740
410 420 430 440 450 460
pF1KE1 GVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKG
NP_000 GDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGER
750 760 770 780 790 800
>--
initn: 1153 init1: 616 opt: 638 Z-score: 310.5 bits: 68.6 E(85289): 1.5e-10
Smith-Waterman score: 638; 43.9% identity (57.0% similar) in 223 aa overlap (148-369:996-1218)
120 130 140 150 160 170
pF1KE1 AQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEK
: :: ::: : : : : :: : :..
NP_000 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRD
970 980 990 1000 1010 1020
180 190 200 210 220 230
pF1KE1 GAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLI
:. :. : : .: : : :: : : :: : : .: .: :: : : :. :
NP_000 GSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP
1030 1040 1050 1060 1070 1080
240 250 260 270 280 290
pF1KE1 GPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAK
::.: : ::: :. : : :: ::. :. :. : :: :..: .: ::: : : : .
NP_000 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS
1090 1100 1110 1120 1130 1140
300 310 320 330 340 350
pF1KE1 GDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATG-LKGSKGDTGL
: :. : .: ::: : : : .:: :: ::::. : :: :: ::: : :. : ...
NP_000 GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAI
1150 1160 1170 1180 1190 1200
360 370 380 390 400 410
pF1KE1 QGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGE
: :.:. . .:
NP_000 AGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDL
1210 1220 1230 1240 1250 1260
>>XP_011526344 (OMIM: 120216) PREDICTED: collagen alpha- (1744 aa)
initn: 4669 init1: 868 opt: 907 Z-score: 431.2 bits: 91.2 E(85289): 2.8e-17
Smith-Waterman score: 915; 46.8% identity (61.4% similar) in 293 aa overlap (141-418:495-787)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
:: .:::.:: : :: .: .: : ::
XP_011 AQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR
470 480 490 500 510 520
180 190 200 210
pF1KE1 PGPPAEKGAKGAMGRDGATGPSGPQG----P--PGVKGE------AGLQGPQGAPGKQGA
: .. :: :: : : :::.: .: : :: ::. .: :: : :..::
XP_011 VGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGA
530 540 550 560 570 580
220 230 240 250 260 270
pF1KE1 TGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGS
: ::: :. : : ::.::.: : :. : :. :. : .: : : :::: ::.
XP_011 EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGN
590 600 610 620 630 640
280 290 300 310 320 330
pF1KE1 KGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGS
.:. : ::: :: : :: :: :.::. :.:: : .:::: .: : :. : : :
XP_011 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP
650 660 670 680 690 700
340 350 360 370 380 390
pF1KE1 PGSPGATGLKGSKGDTGLQGQQGRKGESGVPG---PAGVKGEQGSPGLAGPKGAPGQAGQ
:: :: :.::..:. ::::..:.:::.: :: .:.::.::.:: ::.: : :
XP_011 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGP
710 720 730 740 750 760
400 410 420 430 440 450
pF1KE1 KGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSD
::. : : : : ::::. :
XP_011 KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQ
770 780 790 800 810 820
>--
initn: 1602 init1: 858 opt: 859 Z-score: 409.5 bits: 87.1 E(85289): 4.5e-16
Smith-Waterman score: 862; 45.3% identity (56.0% similar) in 318 aa overlap (141-418:1125-1441)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
::.: ::..:. :. : : :. : :::
XP_011 AGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGP
1100 1110 1120 1130 1140 1150
180 190 200 210
pF1KE1 PGPPAEKGAKGAMGRDGATGPSGPQGP---------------PGVKGEAGLQGPQGAPGK
:: .: : :.:: :: :: ::::: ::. :: : .: : ::
XP_011 PGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP
1160 1170 1180 1190 1200 1210
220 230 240 250 260
pF1KE1 QGATGTPGPQGEKGSKGDGG---------LIGPKGETGTKGEKGDLGLPGSKGDRGMKGD
:: : :::.:. : :::.: :: :: :.:: : ::::. : : :
XP_011 PGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGV
1220 1230 1240 1250 1260 1270
270 280 290 300 310 320
pF1KE1 AGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGS
.:. : :: .:. :: : ::::: .: ::: : :. : .: : : :. :::::::
XP_011 SGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGP
1280 1290 1300 1310 1320 1330
330 340 350 360 370
pF1KE1 AGSPGRAGLP----GSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGP-----------
: :::.: : : :: : ::.: : .: : : :. : :::
XP_011 DGPPGRTG-PMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKG
1340 1350 1360 1370 1380 1390
380 390 400 410 420 430
pF1KE1 -AGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSS
.: :::.: :: : : ::.::.:::::. : .: : ::. : :
XP_011 DTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPG
1400 1410 1420 1430 1440 1450
440 450 460 470 480 490
pF1KE1 NRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWLDNVQCRG
XP_011 VAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGLE
1460 1470 1480 1490 1500 1510
>--
initn: 1424 init1: 757 opt: 835 Z-score: 398.7 bits: 85.1 E(85289): 1.8e-15
Smith-Waterman score: 835; 44.3% identity (59.1% similar) in 296 aa overlap (138-418:822-1111)
110 120 130 140 150 160
pF1KE1 QGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGA
: .::. .::.: :: .:..: : :
XP_011 PGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL---EGERGPPGSRGERGQPGATGQ
800 810 820 830 840
170 180 190 200 210 220
pF1KE1 PGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGE
::: : .. :: : :. : : .:: : :: :: : :: .: ::. : : : ::.
XP_011 PGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQ
850 860 870 880 890 900
230 240 250 260 270 280
pF1KE1 KGSKGDGGLIGPKGETGTKG---EKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGR
: : .:..::.:.:: : :.: : :: :..:. : : : : : : .:.
XP_011 TGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGK
910 920 930 940 950 960
290 300 310 320 330 340
pF1KE1 PGPPGLAGFPGAKGDQGQPG---LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGS
:: :: :::: :: :.:: :.: :::: :: :. :: : : : ::::. ::
XP_011 EGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGS
970 980 990 1000 1010 1020
350 360 370 380 390
pF1KE1 PGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKG---------APGQ
: .: :.::. : .: : :..:.::: : : :: :::.: :::.
XP_011 EGPVGPAGKKGSRGERGPPGPTGKDGIPGPLG---PLGPPGAAGPSGEEGDKGDVGAPGH
1030 1040 1050 1060 1070 1080
400 410 420 430 440 450
pF1KE1 AGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQ
:.:::.: : :. :..: :. :
XP_011 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGP
1090 1100 1110 1120 1130 1140
>>NP_056534 (OMIM: 120216) collagen alpha-3(V) chain pre (1745 aa)
initn: 4669 init1: 868 opt: 907 Z-score: 431.2 bits: 91.2 E(85289): 2.8e-17
Smith-Waterman score: 915; 46.8% identity (61.4% similar) in 293 aa overlap (141-418:496-788)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
:: .:::.:: : :: .: .: : ::
NP_056 AQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR
470 480 490 500 510 520
180 190 200 210
pF1KE1 PGPPAEKGAKGAMGRDGATGPSGPQG----P--PGVKGE------AGLQGPQGAPGKQGA
: .. :: :: : : :::.: .: : :: ::. .: :: : :..::
NP_056 VGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGA
530 540 550 560 570 580
220 230 240 250 260 270
pF1KE1 TGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGS
: ::: :. : : ::.::.: : :. : :. :. : .: : : :::: ::.
NP_056 EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGN
590 600 610 620 630 640
280 290 300 310 320 330
pF1KE1 KGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGS
.:. : ::: :: : :: :: :.::. :.:: : .:::: .: : :. : : :
NP_056 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP
650 660 670 680 690 700
340 350 360 370 380 390
pF1KE1 PGSPGATGLKGSKGDTGLQGQQGRKGESGVPG---PAGVKGEQGSPGLAGPKGAPGQAGQ
:: :: :.::..:. ::::..:.:::.: :: .:.::.::.:: ::.: : :
NP_056 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGP
710 720 730 740 750 760
400 410 420 430 440 450
pF1KE1 KGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSD
::. : : : : ::::. :
NP_056 KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQ
770 780 790 800 810 820
>--
initn: 1602 init1: 858 opt: 859 Z-score: 409.5 bits: 87.1 E(85289): 4.5e-16
Smith-Waterman score: 862; 45.3% identity (56.0% similar) in 318 aa overlap (141-418:1126-1442)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
::.: ::..:. :. : : :. : :::
NP_056 AGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGP
1100 1110 1120 1130 1140 1150
180 190 200 210
pF1KE1 PGPPAEKGAKGAMGRDGATGPSGPQGP---------------PGVKGEAGLQGPQGAPGK
:: .: : :.:: :: :: ::::: ::. :: : .: : ::
NP_056 PGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP
1160 1170 1180 1190 1200 1210
220 230 240 250 260
pF1KE1 QGATGTPGPQGEKGSKGDGG---------LIGPKGETGTKGEKGDLGLPGSKGDRGMKGD
:: : :::.:. : :::.: :: :: :.:: : ::::. : : :
NP_056 PGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGV
1220 1230 1240 1250 1260 1270
270 280 290 300 310 320
pF1KE1 AGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGS
.:. : :: .:. :: : ::::: .: ::: : :. : .: : : :. :::::::
NP_056 SGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGP
1280 1290 1300 1310 1320 1330
330 340 350 360 370
pF1KE1 AGSPGRAGLP----GSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGP-----------
: :::.: : : :: : ::.: : .: : : :. : :::
NP_056 DGPPGRTG-PMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKG
1340 1350 1360 1370 1380 1390
380 390 400 410 420 430
pF1KE1 -AGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSS
.: :::.: :: : : ::.::.:::::. : .: : ::. : :
NP_056 DTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPG
1400 1410 1420 1430 1440 1450
440 450 460 470 480 490
pF1KE1 NRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWLDNVQCRG
NP_056 VAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGLE
1460 1470 1480 1490 1500 1510
>--
initn: 1424 init1: 757 opt: 835 Z-score: 398.6 bits: 85.1 E(85289): 1.8e-15
Smith-Waterman score: 835; 44.3% identity (59.1% similar) in 296 aa overlap (138-418:823-1112)
110 120 130 140 150 160
pF1KE1 QGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGA
: .::. .::.: :: .:..: : :
NP_056 PGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL---EGERGPPGSRGERGQPGATGQ
800 810 820 830 840
170 180 190 200 210 220
pF1KE1 PGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGE
::: : .. :: : :. : : .:: : :: :: : :: .: ::. : : : ::.
NP_056 PGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQ
850 860 870 880 890 900
230 240 250 260 270 280
pF1KE1 KGSKGDGGLIGPKGETGTKG---EKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGR
: : .:..::.:.:: : :.: : :: :..:. : : : : : : .:.
NP_056 TGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGK
910 920 930 940 950 960
290 300 310 320 330 340
pF1KE1 PGPPGLAGFPGAKGDQGQPG---LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGS
:: :: :::: :: :.:: :.: :::: :: :. :: : : : ::::. ::
NP_056 EGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGS
970 980 990 1000 1010 1020
350 360 370 380 390
pF1KE1 PGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKG---------APGQ
: .: :.::. : .: : :..:.::: : : :: :::.: :::.
NP_056 EGPVGPAGKKGSRGERGPPGPTGKDGIPGPLG---PLGPPGAAGPSGEEGDKGDVGAPGH
1030 1040 1050 1060 1070 1080
400 410 420 430 440 450
pF1KE1 AGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQ
:.:::.: : :. :..: :. :
NP_056 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGP
1090 1100 1110 1120 1130 1140
>>NP_001281276 (OMIM: 120252,136800,609140) collagen alp (638 aa)
initn: 1622 init1: 562 opt: 889 Z-score: 427.8 bits: 89.1 E(85289): 4.3e-17
Smith-Waterman score: 889; 47.6% identity (59.7% similar) in 290 aa overlap (141-418:168-454)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
:. . : .: :: : :: : ::.:::
NP_001 GLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP
140 150 160 170 180 190
180 190 200 210 220
pF1KE1 PGPPAEKGAKGAMGRDG-----ATGPSGPQGPPGVKGEAGLQGPQG--APGKQGATGTPG
: :. : :: : :: :.: ::::: :.::: : .:: : .: : : ::
NP_001 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG
:.:..: : ::.: .:: : :: :. : : : :. :.::. : : : ::. :
NP_001 PKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG
::::. :: .:::: :: : :: :: : :::.: :: .: :. :. : ::.::
NP_001 PGGPPGV---PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPG
320 330 340 350 360 370
350 360 370 380 390
pF1KE1 ATGLKGSKGDTGLQGQQGRKGESGVPG---PAGVKGEQGSPGLAGPKGAPGQAGQ--KGD
..: :.::: :: :: : .: ::.:: ::: : :: ::: : : :: :. :.
NP_001 VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGE
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE1 QGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIV
:. : .: :: : : :
NP_001 PGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKG
440 450 460 470 480 490
>--
initn: 465 init1: 186 opt: 482 Z-score: 243.9 bits: 55.1 E(85289): 7.6e-07
Smith-Waterman score: 527; 49.4% identity (59.5% similar) in 168 aa overlap (155-322:10-167)
130 140 150 160 170 180
pF1KE1 VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG
:.:. : : :: ::::::. : : ::
NP_001 MPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPG-MG
10 20 30
190 200 210 220 230 240
pF1KE1 RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG
. : : :: :::: . . : :: : ::: : : :: .:: : .:: :: :: : :
NP_001 KPGLHGQPGPAGPPGFS-RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG
: .: . .::. : .: : :::: :: : :.::::: :. : .: ::::
NP_001 LPGPSG-ITIPGKPGAQG------VPGPPGFQGEPGPQGEPGPPGDRGLKGDNG-VGQPG
100 110 120 130 140
310 320 330 340 350 360
pF1KE1 LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKG
: :.:: :: : :: :
NP_001 LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGP
150 160 170 180 190 200
>>NP_005193 (OMIM: 120252,136800,609140) collagen alpha- (703 aa)
initn: 1622 init1: 562 opt: 889 Z-score: 427.4 bits: 89.1 E(85289): 4.6e-17
Smith-Waterman score: 889; 47.6% identity (59.7% similar) in 290 aa overlap (141-418:233-519)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
:. . : .: :: : :: : ::.:::
NP_005 GLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP
210 220 230 240 250 260
180 190 200 210 220
pF1KE1 PGPPAEKGAKGAMGRDG-----ATGPSGPQGPPGVKGEAGLQGPQG--APGKQGATGTPG
: :. : :: : :: :.: ::::: :.::: : .:: : .: : : ::
NP_005 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG
270 280 290 300 310 320
230 240 250 260 270 280
pF1KE1 PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG
:.:..: : ::.: .:: : :: :. : : : :. :.::. : : : ::. :
NP_005 PKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG
330 340 350 360 370 380
290 300 310 320 330 340
pF1KE1 RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG
::::. :: .:::: :: : :: :: : :::.: :: .: :. :. : ::.::
NP_005 PGGPPGV---PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPG
390 400 410 420 430
350 360 370 380 390
pF1KE1 ATGLKGSKGDTGLQGQQGRKGESGVPG---PAGVKGEQGSPGLAGPKGAPGQAGQ--KGD
..: :.::: :: :: : .: ::.:: ::: : :: ::: : : :: :. :.
NP_005 VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGE
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE1 QGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIV
:. : .: :: : : :
NP_005 PGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKG
500 510 520 530 540 550
>--
initn: 647 init1: 200 opt: 519 Z-score: 260.2 bits: 58.2 E(85289): 9.4e-08
Smith-Waterman score: 533; 42.1% identity (54.1% similar) in 209 aa overlap (145-343:25-232)
120 130 140 150 160 170
pF1KE1 VLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGM-PGAPGPPGP
: .. :: : :. . . : :: ::
NP_005 MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGP
10 20 30 40 50
180 190 200 210 220 230
pF1KE1 PAEKGAKGAMGRDGATGP---SGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGS
: ..: . : .: :::: : : :: : ::: : : :: .:. :
NP_005 PFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGP
60 70 80 90 100 110
240 250 260 270 280
pF1KE1 KGDGGL--IGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGR--PG
: :. .: : : :. : : :: .:. :..:: :. :::: : : : ::
NP_005 AGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPG
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE1 PPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKG--EPGSAGSPGRAGLPGSPGSPGA
:: : :: : ::.:: :: ::::: : : .: .:: :.::..: :: :: ::
NP_005 KPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGP
180 190 200 210 220 230
350 360 370 380 390 400
pF1KE1 TGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGS
NP_005 AGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQG
240 250 260 270 280 290
>>XP_005270534 (OMIM: 120252,136800,609140) PREDICTED: c (780 aa)
initn: 1622 init1: 562 opt: 889 Z-score: 426.9 bits: 89.2 E(85289): 4.9e-17
Smith-Waterman score: 889; 47.6% identity (59.7% similar) in 290 aa overlap (141-418:310-596)
120 130 140 150 160 170
pF1KE1 SRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGP
:. . : .: :: : :: : ::.:::
XP_005 GLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP
280 290 300 310 320 330
180 190 200 210 220
pF1KE1 PGPPAEKGAKGAMGRDG-----ATGPSGPQGPPGVKGEAGLQGPQG--APGKQGATGTPG
: :. : :: : :: :.: ::::: :.::: : .:: : .: : : ::
XP_005 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG
340 350 360 370 380 390
230 240 250 260 270 280
pF1KE1 PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG
:.:..: : ::.: .:: : :: :. : : : :. :.::. : : : ::. :
XP_005 PKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG
400 410 420 430 440 450
290 300 310 320 330 340
pF1KE1 RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG
::::. :: .:::: :: : :: :: : :::.: :: .: :. :. : ::.::
XP_005 PGGPPGV---PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPG
460 470 480 490 500 510
350 360 370 380 390
pF1KE1 ATGLKGSKGDTGLQGQQGRKGESGVPG---PAGVKGEQGSPGLAGPKGAPGQAGQ--KGD
..: :.::: :: :: : .: ::.:: ::: : :: ::: : : :: :. :.
XP_005 VAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGE
520 530 540 550 560 570
400 410 420 430 440 450
pF1KE1 QGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIV
:. : .: :: : : :
XP_005 PGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKG
580 590 600 610 620 630
>--
initn: 647 init1: 200 opt: 519 Z-score: 259.7 bits: 58.3 E(85289): 1e-07
Smith-Waterman score: 533; 42.1% identity (54.1% similar) in 209 aa overlap (145-343:102-309)
120 130 140 150 160 170
pF1KE1 VLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGM-PGAPGPPGP
: .. :: : :. . . : :: ::
XP_005 STSTDAMLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGP
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE1 PAEKGAKGAMGRDGATGP---SGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGS
: ..: . : .: :::: : : :: : ::: : : :: .:. :
XP_005 PFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGLHGQPGP
140 150 160 170 180 190
240 250 260 270 280
pF1KE1 KGDGGL--IGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGR--PG
: :. .: : : :. : : :: .:. :..:: :. :::: : : : ::
XP_005 AGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPG
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE1 PPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKG--EPGSAGSPGRAGLPGSPGSPGA
:: : :: : ::.:: :: ::::: : : .: .:: :.::..: :: :: ::
XP_005 KPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGP
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE1 TGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGS
XP_005 AGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQG
320 330 340 350 360 370
520 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:50:04 2016 done: Sun Nov 6 22:50:06 2016
Total Scan time: 11.780 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]