Result of FASTA (omim) for
pFN21AE1337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1337, 158 aa
1>>>pF1KE1337 158 - 158 aa - 158 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7752+/-0.00029; mu= 14.9432+/- 0.018
mean_var=64.6876+/-13.069, 0's: 0 Z-trim(119.0): 100 B-trim: 3177 in 2/51
Lambda= 0.159464
statistics sampled from 32368 (32506) to 32368 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.381), width: 16
Scan time: 5.440
The best scores are: opt bits E(85289)
NP_038459 (OMIM: 602893) NKG2-F type II integral m ( 158) 1088 258.1 4.2e-69
NP_002251 (OMIM: 602891) NKG2-C type II integral m ( 231) 823 197.3 1.3e-50
NP_002252 (OMIM: 602892) NKG2-E type II integral m ( 240) 810 194.3 1e-49
NP_031359 (OMIM: 602892) NKG2-E type II integral m ( 257) 810 194.3 1.1e-49
NP_001291377 (OMIM: 161555) NKG2-A/NKG2-B type II ( 228) 645 156.3 2.6e-38
NP_002250 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 233) 645 156.4 2.7e-38
NP_998823 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 233) 645 156.4 2.7e-38
NP_998822 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 215) 364 91.7 7.3e-19
NP_015567 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 215) 364 91.7 7.3e-19
NP_001107868 (OMIM: 602894) natural killer cells a ( 179) 163 45.4 5.3e-05
NP_002253 (OMIM: 602894) natural killer cells anti ( 179) 163 45.4 5.3e-05
XP_016874780 (OMIM: 602894) PREDICTED: natural kil ( 179) 159 44.5 0.0001
XP_016874779 (OMIM: 602894) PREDICTED: natural kil ( 185) 159 44.5 0.0001
XP_006719130 (OMIM: 602894) PREDICTED: natural kil ( 185) 159 44.5 0.0001
XP_011518953 (OMIM: 602894) PREDICTED: natural kil ( 186) 159 44.5 0.0001
XP_016874776 (OMIM: 602894) PREDICTED: natural kil ( 219) 159 44.5 0.00012
XP_016874774 (OMIM: 602894) PREDICTED: natural kil ( 220) 159 44.5 0.00012
XP_016874775 (OMIM: 602894) PREDICTED: natural kil ( 220) 159 44.5 0.00012
XP_011518952 (OMIM: 602894) PREDICTED: natural kil ( 220) 159 44.5 0.00012
NP_031386 (OMIM: 611817) NKG2-D type II integral m ( 216) 148 42.0 0.00067
NP_005801 (OMIM: 604874) killer cell lectin-like r ( 189) 136 39.2 0.0041
NP_001316028 (OMIM: 604874) killer cell lectin-lik ( 195) 136 39.2 0.0042
XP_016874173 (OMIM: 604874) PREDICTED: killer cell ( 199) 136 39.2 0.0042
XP_016874171 (OMIM: 604874) PREDICTED: killer cell ( 199) 136 39.2 0.0042
XP_016874174 (OMIM: 604874) PREDICTED: killer cell ( 199) 136 39.2 0.0042
XP_016874172 (OMIM: 604874) PREDICTED: killer cell ( 199) 136 39.2 0.0042
NP_031360 (OMIM: 602894) natural killer cells anti ( 148) 132 38.2 0.0064
XP_016874778 (OMIM: 602894) PREDICTED: natural kil ( 188) 132 38.3 0.0077
XP_016874777 (OMIM: 602894) PREDICTED: natural kil ( 189) 132 38.3 0.0077
>>NP_038459 (OMIM: 602893) NKG2-F type II integral membr (158 aa)
initn: 1088 init1: 1088 opt: 1088 Z-score: 1361.6 bits: 258.1 E(85289): 4.2e-69
Smith-Waterman score: 1088; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
70 80 90 100 110 120
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
::::::::::::::::::::::::::::::::::::::
NP_038 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
130 140 150
>>NP_002251 (OMIM: 602891) NKG2-C type II integral membr (231 aa)
initn: 556 init1: 539 opt: 823 Z-score: 1029.9 bits: 197.3 E(85289): 1.3e-50
Smith-Waterman score: 823; 87.4% identity (90.2% similar) in 143 aa overlap (1-143:1-140)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:::::::.::::::::::::::: :::: :::::.:::::::::::: : .::: :: :
NP_002 MNKQRGTFSEVSLAQDPKRQQRKPKGNKSSISGTEQEIFQVELNLQNPSLNHQGIDKIYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:.::::::::::::::::::::::::::::::::: ::::::: : : :::::::::
NP_002 CQGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIP---FLEQNNFSPNTRTQKARHCGHC
70 80 90 100 110
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
:::::::::::::::::::::::
NP_002 PEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLASILPSSWIGVFR
120 130 140 150 160 170
>>NP_002252 (OMIM: 602892) NKG2-E type II integral membr (240 aa)
initn: 532 init1: 532 opt: 810 Z-score: 1013.5 bits: 194.3 E(85289): 1e-49
Smith-Waterman score: 810; 79.7% identity (85.4% similar) in 158 aa overlap (1-156:1-155)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:.:::::.:::::::::: :::: :::: :::::.:::::::::::::: .::: :: :
NP_002 MSKQRGTFSEVSLAQDPKWQQRKPKGNKSSISGTEQEIFQVELNLQNASLNHQGIDKIYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:.::::::::::::::::::::::::::::::::: ::::: : : : :::::::::
NP_002 CQGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIP---FLEQNNSSPNARTQKARHCGHC
70 80 90 100 110
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEE--RVCWPVLRRTLICFL
::::::::::::::::::::::: ..: .:.:
NP_002 PEEWITYSNSCYYIGKERRTWEESLQACASKNSSSLLCIDNEEEMKFLASILPSSWIGVF
120 130 140 150 160 170
NP_002 RNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLV
180 190 200 210 220 230
>>NP_031359 (OMIM: 602892) NKG2-E type II integral membr (257 aa)
initn: 532 init1: 532 opt: 810 Z-score: 1013.1 bits: 194.3 E(85289): 1.1e-49
Smith-Waterman score: 810; 79.7% identity (85.4% similar) in 158 aa overlap (1-156:1-155)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:.:::::.:::::::::: :::: :::: :::::.:::::::::::::: .::: :: :
NP_031 MSKQRGTFSEVSLAQDPKWQQRKPKGNKSSISGTEQEIFQVELNLQNASLNHQGIDKIYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:.::::::::::::::::::::::::::::::::: ::::: : : : :::::::::
NP_031 CQGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIP---FLEQNNSSPNARTQKARHCGHC
70 80 90 100 110
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEE--RVCWPVLRRTLICFL
::::::::::::::::::::::: ..: .:.:
NP_031 PEEWITYSNSCYYIGKERRTWEESLQACASKNSSSLLCIDNEEEMKFLASILPSSWIGVF
120 130 140 150 160 170
NP_031 RNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIVSISFRIKALE
180 190 200 210 220 230
>>NP_001291377 (OMIM: 161555) NKG2-A/NKG2-B type II inte (228 aa)
initn: 378 init1: 346 opt: 645 Z-score: 808.7 bits: 156.3 E(85289): 2.6e-38
Smith-Waterman score: 645; 67.8% identity (82.5% similar) in 143 aa overlap (1-143:1-142)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:..: ::...: .::::::: :::: :: .:.::: .:::::.::.: ::::::::
NP_001 MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:: : :::: . .:::::..:::.:. :::.:: . ..:: ::: : :::::::::
NP_001 CKDLPSAPEKLIVGILGIICLILMASVV-TIVVIPSTLIQRHNNSSLNTRTQKARHCGHC
70 80 90 100 110
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
:::::::::::::::::::::::
NP_001 PEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFR
120 130 140 150 160 170
>>NP_002250 (OMIM: 161555) NKG2-A/NKG2-B type II integra (233 aa)
initn: 378 init1: 346 opt: 645 Z-score: 808.5 bits: 156.4 E(85289): 2.7e-38
Smith-Waterman score: 645; 67.8% identity (82.5% similar) in 143 aa overlap (1-143:1-142)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:..: ::...: .::::::: :::: :: .:.::: .:::::.::.: ::::::::
NP_002 MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:: : :::: . .:::::..:::.:. :::.:: . ..:: ::: : :::::::::
NP_002 CKDLPSAPEKLIVGILGIICLILMASVV-TIVVIPSTLIQRHNNSSLNTRTQKARHCGHC
70 80 90 100 110
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
:::::::::::::::::::::::
NP_002 PEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFR
120 130 140 150 160 170
>>NP_998823 (OMIM: 161555) NKG2-A/NKG2-B type II integra (233 aa)
initn: 378 init1: 346 opt: 645 Z-score: 808.5 bits: 156.4 E(85289): 2.7e-38
Smith-Waterman score: 645; 67.8% identity (82.5% similar) in 143 aa overlap (1-143:1-142)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:..: ::...: .::::::: :::: :: .:.::: .:::::.::.: ::::::::
NP_998 MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:: : :::: . .:::::..:::.:. :::.:: . ..:: ::: : :::::::::
NP_998 CKDLPSAPEKLIVGILGIICLILMASVV-TIVVIPSTLIQRHNNSSLNTRTQKARHCGHC
70 80 90 100 110
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
:::::::::::::::::::::::
NP_998 PEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFR
120 130 140 150 160 170
>>NP_998822 (OMIM: 161555) NKG2-A/NKG2-B type II integra (215 aa)
initn: 566 init1: 346 opt: 364 Z-score: 459.6 bits: 91.7 E(85289): 7.3e-19
Smith-Waterman score: 552; 61.5% identity (74.8% similar) in 143 aa overlap (1-143:1-124)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:..: ::...: .::::::: :::: :: .:.::: .:::::.::.: ::::::::
NP_998 MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:: : :::: . .:::::..:::.:. :::.:: .::::::
NP_998 CKDLPSAPEKLIVGILGIICLILMASVV-TIVVIP------------------SRHCGHC
70 80 90 100
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
:::::::::::::::::::::::
NP_998 PEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFR
110 120 130 140 150 160
>>NP_015567 (OMIM: 161555) NKG2-A/NKG2-B type II integra (215 aa)
initn: 566 init1: 346 opt: 364 Z-score: 459.6 bits: 91.7 E(85289): 7.3e-19
Smith-Waterman score: 552; 61.5% identity (74.8% similar) in 143 aa overlap (1-143:1-124)
10 20 30 40 50 60
pF1KE1 MNKQRGTYSEVSLAQDPKRQQRKLKGNKISISGTKQEIFQVELNLQNASSDHQGNDKTYH
:..: ::...: .::::::: :::: :: .:.::: .:::::.::.: ::::::::
NP_015 MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKARHCGHC
:: : :::: . .:::::..:::.:. :::.:: .::::::
NP_015 CKDLPSAPEKLIVGILGIICLILMASVV-TIVVIP------------------SRHCGHC
70 80 90 100
130 140 150
pF1KE1 PEEWITYSNSCYYIGKERRTWEERVCWPVLRRTLICFL
:::::::::::::::::::::::
NP_015 PEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFR
110 120 130 140 150 160
>>NP_001107868 (OMIM: 602894) natural killer cells antig (179 aa)
initn: 171 init1: 126 opt: 163 Z-score: 210.8 bits: 45.4 E(85289): 5.3e-05
Smith-Waterman score: 166; 34.1% identity (57.6% similar) in 85 aa overlap (70-143:10-84)
40 50 60 70 80 90
pF1KE1 QVELNLQNASSDHQGNDKTYHCKGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPCIGV
.: . .:::::. :::: .:.
NP_001 MAVFKTTLWRLISGTLGIICLSLMAT----------LGI
10 20
100 110 120 130 140
pF1KE1 LEQNNFSL-----------NRRMQKARHCGHCPEEWITYSNSCYYIGKERRTWEERVCWP
: .:.:. : ..:: : : :.:. : .::.:..:..::.:
NP_001 LLKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLC
30 40 50 60 70 80
150
pF1KE1 VLRRTLICFL
NP_001 ASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSALSQYLFPSFETFNT
90 100 110 120 130 140
158 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:59:17 2016 done: Mon Nov 7 00:59:17 2016
Total Scan time: 5.440 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]