Result of FASTA (omim) for
pFN21AE1321
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1321, 107 aa
1>>>pF1KE1321 107 - 107 aa - 107 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6028+/-0.000284; mu= 13.2488+/- 0.018
mean_var=55.2406+/-11.030, 0's: 0 Z-trim(118.2): 44 B-trim: 120 in 1/50
Lambda= 0.172562
statistics sampled from 30926 (30975) to 30926 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.363), width: 16
Scan time: 4.780
The best scores are: opt bits E(85289)
NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 679 176.2 9.1e-45
NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 610 159.0 1.3e-39
NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 602 157.0 5.4e-39
NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 p ( 114) 297 81.1 4.1e-16
NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 269 74.1 5.1e-14
NP_002695 (OMIM: 121010) platelet basic protein pr ( 128) 264 72.9 1.3e-13
NP_002610 (OMIM: 173460) platelet factor 4 precurs ( 101) 233 65.1 2.3e-11
NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 225 63.1 9e-11
NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 222 62.4 1.8e-10
XP_005265753 (OMIM: 173460) PREDICTED: platelet fa ( 110) 208 58.9 1.8e-09
NP_002611 (OMIM: 173461) platelet factor 4 variant ( 104) 207 58.6 2.1e-09
NP_004878 (OMIM: 604186) C-X-C motif chemokine 14 ( 111) 154 45.5 2.1e-05
NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 153 45.2 2.6e-05
XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 149 44.2 4.8e-05
NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 149 44.2 4.8e-05
NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 145 43.2 8.2e-05
NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 145 43.2 8.5e-05
NP_005400 (OMIM: 604852) C-X-C motif chemokine 11 ( 94) 142 42.4 0.00014
NP_001171605 (OMIM: 600835,609423) stromal cell-de ( 140) 139 41.8 0.00033
NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 ( 98) 135 40.7 0.0005
NP_001289052 (OMIM: 604852) C-X-C motif chemokine ( 106) 130 39.5 0.0013
>>NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 precu (107 aa)
initn: 679 init1: 679 opt: 679 Z-score: 924.7 bits: 176.2 E(85289): 9.1e-45
Smith-Waterman score: 679; 100.0% identity (100.0% similar) in 107 aa overlap (1-107:1-107)
10 20 30 40 50 60
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV
10 20 30 40 50 60
70 80 90 100
pF1KE1 NVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
70 80 90 100
>>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa)
initn: 696 init1: 610 opt: 610 Z-score: 831.9 bits: 159.0 E(85289): 1.3e-39
Smith-Waterman score: 610; 87.9% identity (99.1% similar) in 107 aa overlap (1-107:1-107)
10 20 30 40 50 60
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV
::.:::::::::::::::::::::::::::::::: ..::::::::::::::::::::::
NP_002 MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSV
10 20 30 40 50 60
70 80 90 100
pF1KE1 NVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
.:.::::::::::::::::::.:::::::::::.:::::.:..:..:
NP_002 KVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN
70 80 90 100
>>NP_001502 (OMIM: 155730) growth-regulated alpha protei (107 aa)
initn: 658 init1: 602 opt: 602 Z-score: 821.1 bits: 157.0 E(85289): 5.4e-39
Smith-Waterman score: 602; 86.9% identity (98.1% similar) in 107 aa overlap (1-107:1-107)
10 20 30 40 50 60
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV
::.:.:::::::::::::::::::::::.::::::::.::::::::::::::: ::::::
NP_001 MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSV
10 20 30 40 50 60
70 80 90 100
pF1KE1 NVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
::.::::::::::::::::::.:::::::::.:.:::::.::. ..:
NP_001 NVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
70 80 90 100
>>NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 precu (114 aa)
initn: 315 init1: 283 opt: 297 Z-score: 410.3 bits: 81.1 E(85289): 4.1e-16
Smith-Waterman score: 297; 46.9% identity (76.5% similar) in 98 aa overlap (10-105:14-111)
10 20 30 40 50
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAG--ASVVTELRCQCLQTLQGIHL
::. ..::::: . .:: :.:. :::: :::: ::.:
NP_002 MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHP
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 KNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
: :....: . ::.:...::.:.:::::. ::.: .:...:.:.:::. :.
NP_002 KMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
70 80 90 100 110
>>NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 precu (114 aa)
initn: 288 init1: 245 opt: 269 Z-score: 372.7 bits: 74.1 E(85289): 5.1e-14
Smith-Waterman score: 269; 42.9% identity (76.5% similar) in 98 aa overlap (10-105:14-111)
10 20 30 40 50
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAG--ASVVTELRCQCLQTLQGIHL
::. .:::::: . .:: ..:.::::: ::.. ..
NP_002 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 KNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
:.: ...: ::.:...::.:.:::::..::.: .:...:.:.:::..:.
NP_002 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
70 80 90 100 110
>>NP_002695 (OMIM: 121010) platelet basic protein prepro (128 aa)
initn: 336 init1: 261 opt: 264 Z-score: 365.2 bits: 72.9 E(85289): 1.3e-13
Smith-Waterman score: 264; 48.1% identity (81.8% similar) in 77 aa overlap (25-101:45-121)
10 20 30 40 50
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHL
:. ..... ... .::::.:..: .:::
NP_002 RPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHP
20 30 40 50 60 70
60 70 80 90 100
pF1KE1 KNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
:::::..: . : :: :.:::::::.:.: ::.: .: ..::..: :
NP_002 KNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
80 90 100 110 120
>>NP_002610 (OMIM: 173460) platelet factor 4 precursor [ (101 aa)
initn: 176 init1: 151 opt: 233 Z-score: 325.0 bits: 65.1 E(85289): 2.3e-11
Smith-Waterman score: 233; 44.0% identity (72.5% similar) in 91 aa overlap (11-101:10-99)
10 20 30 40 50 60
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV
: : :: ..:::: ::.: .: : .:.: :..: . .. ..: :.
NP_002 MSSAAGFCASRPGLLFLGLLLLPLVVAFA-SAEAEEDGDLQCLCVKTTSQVRPRHITSL
10 20 30 40 50
70 80 90 100
pF1KE1 NVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
.: . :::: ...:::::::.: ::. .:. .:::.:.:
NP_002 EVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
60 70 80 90 100
>>NP_000575 (OMIM: 146930) interleukin-8 precursor [Homo (99 aa)
initn: 215 init1: 150 opt: 225 Z-score: 314.3 bits: 63.1 E(85289): 9e-11
Smith-Waterman score: 225; 40.7% identity (70.3% similar) in 91 aa overlap (16-103:5-95)
10 20 30 40 50
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAAS--RRAAGASVVTELRCQCLQTL-QGIHLKNI
: :::: .:..:. . :. . ::::::..: . .: : :
NP_000 MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFI
10 20 30 40
60 70 80 90 100
pF1KE1 QSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
. . : :::::.::.:. :..:.. ::.: ::...::.:..
NP_000 KELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
50 60 70 80 90
>>NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 precu (125 aa)
initn: 193 init1: 143 opt: 222 Z-score: 308.9 bits: 62.4 E(85289): 1.8e-10
Smith-Waterman score: 222; 40.7% identity (77.9% similar) in 86 aa overlap (15-99:7-88)
10 20 30 40 50
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQG-IHLKNIQS
:. ....::.:.... :. :: . ::.:..: :: :::.....
NP_002 MKKSGVLFLLGIILLVLIGVQ----GTPVVRKGRCSCISTNQGTIHLQSLKD
10 20 30 40
60 70 80 90 100
pF1KE1 VNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
.. .:.: : . :.::::::: ..:::: : :...:.:
NP_002 LKQFAPSPSCEKIEIIATLKNGVQTCLNPDSADVKELIKKWEKQVSQKKKQKNGKKHQKK
50 60 70 80 90 100
NP_002 KVLKVRKSQRSRQKKTT
110 120
>>XP_005265753 (OMIM: 173460) PREDICTED: platelet factor (110 aa)
initn: 188 init1: 151 opt: 208 Z-score: 290.8 bits: 58.9 E(85289): 1.8e-09
Smith-Waterman score: 208; 37.2% identity (66.0% similar) in 94 aa overlap (8-101:20-108)
10 20 30 40
pF1KE1 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQT
:::. : :. : .. : . : .:.: :..:
XP_005 MITATLNGEPAECLATVPGAAPAPPTWLEQLLSGGGVIYAEAEEDG-----DLQCLCVKT
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 LQGIHLKNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
. .. ..: :..: . :::: ...:::::::.: ::. .:. .:::.:.:
XP_005 TSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
60 70 80 90 100 110
107 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:48:51 2016 done: Sun Nov 6 22:48:52 2016
Total Scan time: 4.780 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]